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US20150045403 Pharmaceutical Cream Compositions and Methods of Use  
Embodiments relating to cream formulations as well as oxymetazoline creams and methods for treating rosacea and symptoms associated with rosacea, including, for example, papules, pustules, phymas...
US20130303564 METHOD FOR TREATING A NEURODEGENERATIVE DISORDER  
Provided herein are methods and materials for treating neurodegenerative disorders. The methods may use inhibitors of small G-proteins, such as p21rac, p21ras, or the combination thereof. The...
US20140309195 SMALL MOLECULES THAT PROMOTE SKIN REGENERATION  
Provided herein are small molecules for the induction of fibroblast proliferation and increased secretion or production of proteins. The small molecules described herein can be used for the...
US20110237563 FAST DISSOLVING DRUG DELIVERY SYSTEMS  
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,...
US20110300227 MALIGNANT NEOPLASM TREATMENT PROTOCOL  
Methods, compositions, and strategies for the treatment of malignant neoplasms are presented herein. The treatment modalities are directed towards exploiting characteristics of cancer cells as...
US20150023955 Treatment and Diagnosis of Melanoma  
The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.
US20150209331 HISTAMINE BALANCE RESTORATION METHODS  
Several embodiments provided herein relate to histamine dosing regimens are and uses of such regimens in the restoration of histamine balance in subjects suffering from, for example, histapenia...
US20140309268 METHODS FOR RESTORATION OF HISTAMINE BALANCE  
Several embodiments provided herein relate to histamine dosing regimens are and uses of such regimens in the restoration of histamine balance in subjects suffering from, for example, histapenia...
US20130023573 ALPHA-2 ADRENERGIC MODULATORS FOR TREATING VISUAL DISORDERS MEDIATED BY CENTRAL VISUAL PROJECTIONS FROM THE EYE  
The present invention relates to a method for treating visual disorders mediated by lateral geniculate nucleus, superior colliculus and the visual cortex by administering to a patient in need of...
US20110293520 NEW DRUG FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES LINKED TO PROTEIN AGGREGATION AND/OR NEURODEGENERATIVE DISEASES  
The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of...
US20130108688 Delivery of H2 Antagonists  
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist...
US20110135716 DELIVERY OF H2 ANTAGONISTS  
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist...
US20150094318 METHODS OF COLCHICINE ADMINISTRATION  
The invention provides improved methods for coadministration of colchicine with drugs metabolized by CYP3A4 (anciently referred to as cytochrome P450 isozyme 3A4) or the P-glycoprotein...
US20150094317 METHODS OF COLCHICINE ADMINISTRATION  
The invention provides improved methods for coadministration of colchicine with drugs metabolized by CYP3A4 (anciently referred to as cytochrome P450 isozyme 3A4) or the P-glycoprotein...
US20120065152 PRODRUGS OF GUANFACINE  
Prodrugs of guanfacine, pharmaceutical compositions containing such prodrugs and a method for providing therapeutic benefit in the treatment of ADHD/ODD (attention deficient hyperactivity disorder...
US20130142768 Method for Improving Eye Health  
The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of...
US20060116355 Eye care kit for treating periocular disease  
A care compliance kit is revealed to minimize and prevent the spreading of highly contagious bacterial and viral ocular diseases, to improve conditions for healing, to optimize the functioning of...
US20110076244 SURFACE COATINGS FOR SKIN  
The present invention relates to skin coating compositions and methods and, in particular, to coatings containing an active agent. In some embodiments, the coating may be applied to a skin surface...
US20150017260 COMPOSITIONS OF NUTRITION SUPPLEMENTATION FOR NUTRITIONAL DEFICIENCIES AND METHOD OF USE THEREOF  
A nutritional supplement composition for treating nutritional deficiencies caused by a medical condition in subjects is disclosed. The present application further discloses a method of using a...
US20150087677 METHODS FOR TREATING VESTIBULOTOXICTY  
The present invention relates to a method for treating platinum drugs induced vestibulotoxicity, comprising administering a compound that impairs or prevents accumulation of platinum drugs within...
US20060039935 Composition of a transdermal delivery system, which modulates inflammation, via insitu systems, thereby promoting repair of injured, damaged or diseased joints, and soft tissue.  
The present invention relates to a composition comprising a mixture of nutritional co-factors synergistically combined and applied as a transdermal surfactant. Said surfactant has the ability to...
US20130005775 METHODS OF TREATING ULCERATIVE COLITIS  
Methods of treating and managing ulcerative colitis, using imidazole-based compounds that inhibit S1P lyase, are disclosed.
US20110200597 SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE  
The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of...
US20120178672 Compositions and Methods for Sparing Muscle in Renal Insufficiency and During Hemodialysis  
A nutritional composition and method of use that improves the net balance in skeletal muscle by targeting both the synthetic and breakdown processes. The disclosed composition provides for...
US20120322769 METHODS OF REDUCING VIRULENCE IN BACTERIA  
A method of reducing virulence in a bacterium comprising at least one of a GacS/GacA-type system, a HrpX/HrpY-type system, a T3SS-type system, and a Rsm-type system, the method comprising...
US20140004082 METHODS FOR TREATING LEUKEMIA AND DISORDERS MEDIATED BY CBFBETA AND RUNX1 PROTEINS  
A method for treating core binding factor (CBF) leukemia in a subject, comprising administering to a subject having CBF leukemia a therapeutically effective amount of a compound, or a...
US20150133370 Dietary Compositions and Methods for Protection Against Chemotherapy, Radiotherapy, Oxidative Stress, and Aging  
The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for...
US20120009183 METHOD FOR TREATMENT OF PANCREATITIS  
A method for treating acute or chronic pancreatitis in a subject comprises administering to the subject a therapeutically effective amount of an ACE2 inhibitor.
US20130090307 BACLOFEN AND ACAMPROSATE BASED THERAPY OF NEUROLOGICAL DISORDERS  
The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present...
US20140051738 Oxymetazoline For The Treatment Of Ano-Rectal Disorders  
Methods for treating fecal incontinence by administering to a subject in need thereof compositions including oxymetazoline as an active ingredient. Kits including compositions of oxymetazoline...
US20120083516 Nasal sinus spray for treatment of sinus headache and method of using same  
Disclosed is a nasal spray containing the combination of a vasoconstrictor and a topical local anesthetic.
US20140121256 METHOD OF TREATING MUSCULAR WEAKNESS COMPRISING ADMINISTERING A COMPOSITION COMPRISING AN EFFECTIVE AMOUNT OF HISTAMINE AND/OR SEROTONIN  
The present invention relates to a treatment of muscle weakness resulting from a disease state or injury in a subject suffering therefrom by administering a composition including histamine in an...
US20120088788 SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS  
Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore...
US20120277245 Method of Increasing Intratumoral pHe and Reducing Acid-Mediated Invasion  
A method of treating cancer or inhibiting metastasis in a subject by increasing intratumoral extracellular pH is presented. The method includes administering to the subject a therapeutically...
US20140051729 COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE MUSCLE CONDITIONS  
Methods and compositions for treating degenerative muscle conditions are disclosed. The compositions disclosed herein include S1P promoting compositions that include an S1P promoting agent....
US20140271955 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS  
Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes.
US20120108592 PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES  
A new class of salicylanilides is described. These compounds show strong activity against hepatitis viruses.
US20110288076 Sphingosine-1-Phosphate Receptor Antagonists  
This disclosure relates to sphingosine-1-phosphate (S1P) receptor antagonists, compositions comprising the S1P receptor antagonists and methods for using and processes for making the S1P receptor...
US20110104305 COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT  
Methods for therapy of cystic fibrosis and other conditions such as cancer are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a...
US20130040904 METHOD OF TREATMENT USING ALPHA-1-ADRENERGIC AGONIST COMPOUNDS  
Methods for treating or preventing cardiomyopathy in a subject by administering an α1 adrenergic receptor agonist, wherein the treatment does not result in increased blood pressure are provided.
US20120164139 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders  
Provided herein are methods of treating gastrointestinal motility disorders by targeting the dopamine 3 receptor (D3R). A D3R agonist is administered to a subject to decrease gastrointestinal...
US20100331235 Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases  
Histidine and/or a derivative thereof. In some embodiments, the histidine and/or a derivative thereof is used in maintaining and/or improving barrier function of the skin of a subject. In some...
US20060165814 Amines, combination of amines and vanadium and amine vanadium salts for the treatment or prevention of dyslipidemia  
Combinations comprising vanadium (IV)/(V) compounds and pharmaceutically acceptable amines are provided. Combinations thereof are provided for the treatment or prevention of dyslipidemia,...
US20110053942 ORALLY DISINTEGRATING TABLETS  
The present invention relates to an orally disintegrating tablet containing (1) an active ingredient, (2) mannitol, (3) crystalline cellulose and (4) at least two kinds of particular ingredients...
US20140038974 Compositions and Methods for Eye Whitening  
The invention provides compositions and methods for whitening of eyes and/or reducing redness of eyes. The provided compositions and methods utilize low concentrations of selective α-2 adrenergic...
US20140155449 NEW USE OF L-HISTIDINE AND DERIVATIVES THEREOF  
The present invention discloses the use of L-Histidine to reduce Gadolinium accumulation into target organs, preventing its toxic effects, after administration of gadolinium based contrast agents....
US20110288111 INHIBITION OF INFLUENZA M2 PROTON CHANNEL  
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza...
US20140287988 MACROGOL 15 HYDROXYSTEARATE FORMULATIONS  
Provided herein are compositions, which include an active pharmaceutical ingredient and macrogol 15 hydroxystearate, and methods for using the same for treating diseases or disorder.
US20130035362 Stable Anti-inflammatory Solutions for Injection  
The present invention relates to stable liquid formulations of ketoprofen, amitriptyline, and oxymetazoline.
US20140005244 FAMILY OF POLYAMINE ARYLETHYLAMIDE COMPOUNDS, AND THEIR COSMETIC OR DERMOCOSMETIC USE  
The invention relates to a family of stable polyamine arylethylamide compounds, and to the use of these compounds as agents inhibiting DNA damages induced by by-products of the non-enzymatic...