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US20110237563 |
FAST DISSOLVING DRUG DELIVERY SYSTEMS
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,... |
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US20130231311 |
NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,... |
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US20110124694 |
BIOAVAILABLE COMPOSITIONS OF METAXALONE AND PROCESSES FOR PRODUCING THE SAME
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of... |
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US20130245082 |
BIOAVAILABLE COMPOSITIONS OF METAXOLONE COMPRISING NONVOLATILE LIQUIDS AND PROCESSES FOR PRODUCING THE SAME
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of... |
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US20130004444 |
COMPOSITION CONTAINING AT LEAST ONE C7 SUGAR FOR ALOPECIA TREATMENT, COSMETIC TREATMENT OF HAIR AND NAILS, AND CARE OF HAIR, EYELASHES, OR NAILS
The present invention relates to a composition including at least one C7 sugar, or derivative from esterification of said sugar, and a pharmaceutically acceptable carrier for treating alopecia.... |
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US20130344116 |
Oral particle consisting of an amorphous structure and a submicron domain
The present invention relates to compositions and methods of the preparation of an oral particle essentially consisting of an amorphous structure and a submicron domain, wherein both amorphous... |
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US20120035124 |
USE OF NIFURATEL TO TREAT INFECTIONS CAUSED BY ATOPOBIUM SPECIES
The present invention is directed to the use of nifuratel, or a physiologically acceptable salt thereof, to treat' infections caused by Atopobium species. The invention is further directed to the... |
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US20140315808 |
INHIBITION OF THE RENIN-ANGIOTENSIN SYSTEM FOR THE TREATMENT OF RENAL, VASCULAR AND CARTILAGE PATHOLOGY
A method of treating a disease or condition in which up-regulating GAGs is therapeutically beneficial is disclosed. The method comprises locally administering to a subject a therapeutically... |
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US20110305640 |
METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS
Soluble adenylyl cyclase (sAC) is implicated in proliferation of keratinocytes. Inhibitors of sAC are useful for the treatment and/or prevention of psoriasis and other hyperproliferative skin... |
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US20110195944 |
MODIFIED RELEASE EMULSIONS FOR APPLICATION TO SKIN OR VAGINAL MUCOSA
Modified release oil in water emulsions that delivers drugs to a target tissue. The emulsions according to the present invention contain the lipophilic active ingredient completely dissolved into... |
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US20110319398 |
INHIBITION OF YOPS TRANSLOCATION
The disclosure relates to compounds and methods of inhibiting type three secretion system effector molecules, to methods of detecting compounds that inhibit Yops translocation, and to methods of... |
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US20130245083 |
METHODS OF TREATMENT WITH BIOAVAILABLE COMPOSITIONS OF METAXALONE COMPRISING NONVOLATILE LIQUIDS
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of... |
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US20110288080 |
Nitrofuran Compounds for the Treatment of Cancer and Angiogenesis
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The... |
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US20110081428 |
Use of thioflavin-like compounds to increase life span and/or health span
The present invention provides a method of using thioflavin and functionally similar compounds to increase life span and/or health span. |
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US20100331330 |
METHODS AND COMPOSITIONS FOR TREATING ISCHEMIC STROKE
A method of treating a cerebrovascular accident in a subject includes administering a therapeutically effective amount of at least one PPARγ agonist or a derivative thereof to the subject after... |
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US20100297031 |
ORODISPERSIBLE TABLETS
This invention relates to a an orally disintegrating tablet obtainable by direct compression of a dry powdered mixture, said mixture comprising up to 15% by weight of calcium silicate, at least... |
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US20130131042 |
SPIROXAZOLIDINONE COMPOUNDS
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of... |
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US20120115912 |
RXR AGONIST COMPOUNDS AND METHODS
A method of treating a PPARγ and/or RXR related disease or disorder in a subject includes adminstering to the subject an RXR agonist alone or in combination with a PPARγ agonist. |
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US20150033373 |
Canola Variety Hybrid VR 9561 GS
A novel canola variety designated VR 9561 GS and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred canola varieties. Methods for... |
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US20130121978 |
CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS
Compositions and methods for controlling molluscs, members of the Gastropoda and Bivalvia classes which includes but is not limited to lactones, lactams, carbamates, amides, and/or carboxylic acid... |
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US20130045967 |
COMPOUNDS FOR MODULATING INTEGRIN CDIIb/CDI8
The application describes an assay for the identification of small molecule modulators of integrin CD11b/CD18 and small molecules capable of modulating activity of this receptor. Such compounds... |
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US20110218223 |
TOPICAL VASOCONSTRICTOR PREPARATIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY
Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages... |
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US20140051689 |
Polycyclic Agents for the Treatment of Respiratory Syncytial Virus Infections
Compounds of formula (I), and their use as in the treatment of infections involving viruses of the Pneumovirinae sub-family (RSV) are disclosed. In the formula ring (A) may be phenyl, pyridyl... |
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US20100016363 |
Fixed Combination Dosage Forms for the Treatment of Migraine
Therapeutic regimens and dosage forms are disclosed for the treatment of migraine headache. The regimens preferably combine a serotonin receptor agonist, such as sumatriptan, eletriptan or... |
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US20120108570 |
Pharmacological Treatment for Sleep Apnea
The present invention relates generally to pharmacological methods for the prevention of amelioration of sleep-related breathing disorders via administration of agents or combinations of agents... |
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US20110002967 |
Methods of Transdermally Administering an Indole Serotonin Receptor Agonist and Transdermal Compositions for Use in the Same
Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin... |
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US20100136024 |
Selective Inhibition of Histone Deacetylase 6 for Ocular Neuroprotection or for Treatment or Control of Glaucoma
A composition comprises a material capable of selectively controlling a level or activity of HDAC6 in an ocular environment for effecting ocular neuroprotection in subjects in risk of developing... |
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US20120283264 |
Oxazolidinones as Modulators of MGLUR5
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands, agonists and partial... |
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US20060167045 |
Combination therapy using a dual ppar alpha/gamma agonist and an angiotensin II type I receptor antagonist
The present invention relates to the treatment of hypertension and type 2 diabetes, Metabolic Syndrome or a pre-diabetic state, by the administration of a therapeutically effective amount of a... |
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US20080021021 |
Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist
(1) A preventive and/or a remedy for lower urinary tract diseases such as inflammation in the lower urinary tract, cystitis (interstitial cystitis, etc.) and urethritis; (2) an agent for improving... |
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US20110293673 |
ORAL FILM-FORM BASE AND ORAL FILM-FORM PREPARATION
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a... |
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US20100087422 |
TREATMENT OF ADHD
A method is described for treating attention deficit hyperactivity disorder (ADHD), by administering to the individual an anti-epileptic mood stabiliser at a dose which is sub-therapeutic for mood... |
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US20110077272 |
PULMONARY FORMULATIONS OF TRIPTANS
A pharmaceutical composition includes triptans, such as sumatriptan, and may be used in therapy. The composition may be administered via the inhaled route. |
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US20080249148 |
Synthesis and characterization of polymorph form III 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile
A polymorph Form III of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzoni
trile and methods of preparing Form III are described. Also provided are methods of contraception, treating or... |
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US20130065885 |
ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM
The present invention relates generally to therapeutic formulations. More particularly, this present invention provides an oral delivery system for a therapeutic compound that is a base, a salt of... |
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US20120238607 |
SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF
The present application relates to new, substituted 2-acetamido-5-aryl-1,2,4-triazolones, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention... |
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US20130184301 |
Methods of Treating Post-Traumatic Stress Disorder Using Pro-Neurogenic Compounds
This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. |
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US20140315953 |
METHOD AND COMPOSITION FOR TREATING MIGRAINES
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and... |
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US20120071510 |
Method and Composition for Treating Migraines
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and... |
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US20110288138 |
ORALLY DISINTEGRATING TABLETS OF ZOLMITRIPTAN AND PROCESS FOR PREPARING THE SAME
Silicon dioxide free orally disintegrating tablet formulations of zolmitriptan or a pharmaceutically acceptable salt thereof having magnesium carbonate heavy and sodium stearyl fumarate with one... |
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US20110237625 |
SUBSTITUTED PHENOXY THIAZOLIDINEDIONES AS ESTROGEN RELATED RECEPTOR-á MODULATORS
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not... |
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US20120083500 |
OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X 2/3 ANTAGONISTS
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, X, Y, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of using the compounds for... |
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US20100247606 |
INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS
Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to... |
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US20090028802 |
ORGANOLEPTICALLY ACCEPTABLE INDOLE SEROTONIN RECEPTOR AGONIST ORAL DOSAGE FORMULATIONS AND METHODS OF USING THE SAME
Organoleptically acceptable oral dosage formulations of an indole receptor serotonin agonist, and methods of making and using the same, are provided. An aspect of the formulations is that they... |
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US20130217732 |
Selective Androgen Receptor Modulators
This invention provides compounds of formula I, pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable excipient, methods of modulating the androgen... |
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US20140343018 |
Anti-depression Compounds
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or... |
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US20150031685 |
SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS
The present invention relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3,... |
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US20090215775 |
Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer
Compounds of formula (I) are disclosed for treatment of cancer. |
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US20120301439 |
INHIBITION OF CHOROIDAL NEOVASCULARIZATION
Methods of treatment of diseases that include or are characterized by inappropriate or pathological neovascularization are disclosed. These diseases include diseases of the eye, such as diabetic... |
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US20070123569 |
THERAPEUTIC METHODS USING PROSTAGLANDIN EP4 AGONIST COMPONENTS
Methods are provided directed to adminstering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to affliction with a disease or... |