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US20110237563 FAST DISSOLVING DRUG DELIVERY SYSTEMS  
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,...
US20130231311 NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE  
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,...
US20110124694 BIOAVAILABLE COMPOSITIONS OF METAXALONE AND PROCESSES FOR PRODUCING THE SAME  
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of...
US20130245082 BIOAVAILABLE COMPOSITIONS OF METAXOLONE COMPRISING NONVOLATILE LIQUIDS AND PROCESSES FOR PRODUCING THE SAME  
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of...
US20130004444 COMPOSITION CONTAINING AT LEAST ONE C7 SUGAR FOR ALOPECIA TREATMENT, COSMETIC TREATMENT OF HAIR AND NAILS, AND CARE OF HAIR, EYELASHES, OR NAILS  
The present invention relates to a composition including at least one C7 sugar, or derivative from esterification of said sugar, and a pharmaceutically acceptable carrier for treating alopecia....
US20130344116 Oral particle consisting of an amorphous structure and a submicron domain  
The present invention relates to compositions and methods of the preparation of an oral particle essentially consisting of an amorphous structure and a submicron domain, wherein both amorphous...
US20120035124 USE OF NIFURATEL TO TREAT INFECTIONS CAUSED BY ATOPOBIUM SPECIES  
The present invention is directed to the use of nifuratel, or a physiologically acceptable salt thereof, to treat' infections caused by Atopobium species. The invention is further directed to the...
US20140315808 INHIBITION OF THE RENIN-ANGIOTENSIN SYSTEM FOR THE TREATMENT OF RENAL, VASCULAR AND CARTILAGE PATHOLOGY  
A method of treating a disease or condition in which up-regulating GAGs is therapeutically beneficial is disclosed. The method comprises locally administering to a subject a therapeutically...
US20110305640 METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS  
Soluble adenylyl cyclase (sAC) is implicated in proliferation of keratinocytes. Inhibitors of sAC are useful for the treatment and/or prevention of psoriasis and other hyperproliferative skin...
US20110195944 MODIFIED RELEASE EMULSIONS FOR APPLICATION TO SKIN OR VAGINAL MUCOSA  
Modified release oil in water emulsions that delivers drugs to a target tissue. The emulsions according to the present invention contain the lipophilic active ingredient completely dissolved into...
US20110319398 INHIBITION OF YOPS TRANSLOCATION  
The disclosure relates to compounds and methods of inhibiting type three secretion system effector molecules, to methods of detecting compounds that inhibit Yops translocation, and to methods of...
US20130245083 METHODS OF TREATMENT WITH BIOAVAILABLE COMPOSITIONS OF METAXALONE COMPRISING NONVOLATILE LIQUIDS  
Pharmaceutical compositions comprising metaxalone which demonstrate improved dissolution and bioavailability characteristics compared to the commercially available product, and methods of...
US20110288080 Nitrofuran Compounds for the Treatment of Cancer and Angiogenesis  
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The...
US20110081428 Use of thioflavin-like compounds to increase life span and/or health span  
The present invention provides a method of using thioflavin and functionally similar compounds to increase life span and/or health span.
US20100331330 METHODS AND COMPOSITIONS FOR TREATING ISCHEMIC STROKE  
A method of treating a cerebrovascular accident in a subject includes administering a therapeutically effective amount of at least one PPARγ agonist or a derivative thereof to the subject after...
US20100297031 ORODISPERSIBLE TABLETS  
This invention relates to a an orally disintegrating tablet obtainable by direct compression of a dry powdered mixture, said mixture comprising up to 15% by weight of calcium silicate, at least...
US20130131042 SPIROXAZOLIDINONE COMPOUNDS  
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of...
US20120115912 RXR AGONIST COMPOUNDS AND METHODS  
A method of treating a PPARγ and/or RXR related disease or disorder in a subject includes adminstering to the subject an RXR agonist alone or in combination with a PPARγ agonist.
US20150033373 Canola Variety Hybrid VR 9561 GS  
A novel canola variety designated VR 9561 GS and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred canola varieties. Methods for...
US20130121978 CHEMICAL AND BIOLOGICAL AGENTS FOR THE CONTROL OF MOLLUSCS  
Compositions and methods for controlling molluscs, members of the Gastropoda and Bivalvia classes which includes but is not limited to lactones, lactams, carbamates, amides, and/or carboxylic acid...
US20130045967 COMPOUNDS FOR MODULATING INTEGRIN CDIIb/CDI8  
The application describes an assay for the identification of small molecule modulators of integrin CD11b/CD18 and small molecules capable of modulating activity of this receptor. Such compounds...
US20110218223 TOPICAL VASOCONSTRICTOR PREPARATIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY  
Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages...
US20140051689 Polycyclic Agents for the Treatment of Respiratory Syncytial Virus Infections  
Compounds of formula (I), and their use as in the treatment of infections involving viruses of the Pneumovirinae sub-family (RSV) are disclosed. In the formula ring (A) may be phenyl, pyridyl...
US20100016363 Fixed Combination Dosage Forms for the Treatment of Migraine  
Therapeutic regimens and dosage forms are disclosed for the treatment of migraine headache. The regimens preferably combine a serotonin receptor agonist, such as sumatriptan, eletriptan or...
US20120108570 Pharmacological Treatment for Sleep Apnea  
The present invention relates generally to pharmacological methods for the prevention of amelioration of sleep-related breathing disorders via administration of agents or combinations of agents...
US20110002967 Methods of Transdermally Administering an Indole Serotonin Receptor Agonist and Transdermal Compositions for Use in the Same  
Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin...
US20100136024 Selective Inhibition of Histone Deacetylase 6 for Ocular Neuroprotection or for Treatment or Control of Glaucoma  
A composition comprises a material capable of selectively controlling a level or activity of HDAC6 in an ocular environment for effecting ocular neuroprotection in subjects in risk of developing...
US20120283264 Oxazolidinones as Modulators of MGLUR5  
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands, agonists and partial...
US20060167045 Combination therapy using a dual ppar alpha/gamma agonist and an angiotensin II type I receptor antagonist  
The present invention relates to the treatment of hypertension and type 2 diabetes, Metabolic Syndrome or a pre-diabetic state, by the administration of a therapeutically effective amount of a...
US20080021021 Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist  
(1) A preventive and/or a remedy for lower urinary tract diseases such as inflammation in the lower urinary tract, cystitis (interstitial cystitis, etc.) and urethritis; (2) an agent for improving...
US20110293673 ORAL FILM-FORM BASE AND ORAL FILM-FORM PREPARATION  
The present invention provides a film-form base having one or more sugars or sugar alcohols dispersed as fine particles therein, and also provides a film-form preparation containing the base and a...
US20100087422 TREATMENT OF ADHD  
A method is described for treating attention deficit hyperactivity disorder (ADHD), by administering to the individual an anti-epileptic mood stabiliser at a dose which is sub-therapeutic for mood...
US20110077272 PULMONARY FORMULATIONS OF TRIPTANS  
A pharmaceutical composition includes triptans, such as sumatriptan, and may be used in therapy. The composition may be administered via the inhaled route.
US20080249148 Synthesis and characterization of polymorph form III 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzonitrile  
A polymorph Form III of 4-(2-(4,4-dimethyl-2-oxooxazolidin-3-yl)thiazol-4-yl)benzoni trile and methods of preparing Form III are described. Also provided are methods of contraception, treating or...
US20130065885 ORAL THERAPEUTIC COMPOUND DELIVERY SYSTEM  
The present invention relates generally to therapeutic formulations. More particularly, this present invention provides an oral delivery system for a therapeutic compound that is a base, a salt of...
US20120238607 SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF  
The present application relates to new, substituted 2-acetamido-5-aryl-1,2,4-triazolones, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention...
US20130184301 Methods of Treating Post-Traumatic Stress Disorder Using Pro-Neurogenic Compounds  
This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death.
US20140315953 METHOD AND COMPOSITION FOR TREATING MIGRAINES  
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and...
US20120071510 Method and Composition for Treating Migraines  
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and...
US20110288138 ORALLY DISINTEGRATING TABLETS OF ZOLMITRIPTAN AND PROCESS FOR PREPARING THE SAME  
Silicon dioxide free orally disintegrating tablet formulations of zolmitriptan or a pharmaceutically acceptable salt thereof having magnesium carbonate heavy and sodium stearyl fumarate with one...
US20110237625 SUBSTITUTED PHENOXY THIAZOLIDINEDIONES AS ESTROGEN RELATED RECEPTOR-á MODULATORS  
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not...
US20120083500 OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X 2/3 ANTAGONISTS  
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, X, Y, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of using the compounds for...
US20100247606 INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS  
Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to...
US20090028802 ORGANOLEPTICALLY ACCEPTABLE INDOLE SEROTONIN RECEPTOR AGONIST ORAL DOSAGE FORMULATIONS AND METHODS OF USING THE SAME  
Organoleptically acceptable oral dosage formulations of an indole receptor serotonin agonist, and methods of making and using the same, are provided. An aspect of the formulations is that they...
US20130217732 Selective Androgen Receptor Modulators  
This invention provides compounds of formula I, pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable excipient, methods of modulating the androgen...
US20140343018 Anti-depression Compounds  
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or...
US20150031685 SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS  
The present invention relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3,...
US20090215775 Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer  
Compounds of formula (I) are disclosed for treatment of cancer.
US20120301439 INHIBITION OF CHOROIDAL NEOVASCULARIZATION  
Methods of treatment of diseases that include or are characterized by inappropriate or pathological neovascularization are disclosed. These diseases include diseases of the eye, such as diabetic...
US20070123569 THERAPEUTIC METHODS USING PROSTAGLANDIN EP4 AGONIST COMPONENTS  
Methods are provided directed to adminstering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to affliction with a disease or...

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