Match Document Document Title
US20150126507 COMPOUNDS TO TREAT HEARING LOSS  
The invention is directed, in part, to compounds of structure (I) to treat or prevent hearing loss. Compounds of the present invention also promote sensory hair cell regeneration. Particular...
US20110098303 Method of promoting nail growth using thyromimetic compounds  
The present invention provides methods and compositions for increasing the rate of nail growth in mammals, especially humans, using thyromimetic compounds.
US20140348811 COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS  
The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.
US20140187607 METHODS OF MODULATING COMPLIANCE OF THE TRABECULAR MESHWORK  
The present invention relates to method, system, and composition for modulating the compliance of the trabecular meshwork, which may provide treatment to glaucoma.
US20140348774 METHOD FOR TREATING WOUNDS AND TISSUE REPAIR  
The present inventions relate to a number of fields including wound healing, a waterless antibacterial disinfectant, a surgical scrub, insect repellant, and methods of treating traumatic injuries,...
US20140187595 Methods and Compositions Comprising AMPK Activator (Metformin/Troglitazone) for the Treatment of Myotonic Dystrophy Type 1 (DM1)  
The present invention relates to methods and compositions for the treatment of Myotonic Dystrophy type 1 (DM1) with an AMPK activator .
US20130085169 METHODS AND COMPOSITIONS COMPRISING AMPK ACTIVATOR (METFORMIN/TROGLITAZONE) FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 (DM1)  
The present invention relates to methods and compositions for the treatment of Myotonic Dystrophy type 1 (DM1) with an AMPK activator .
US20130338165 Use of Compounds Elevating Glutathione Levels for the Treatment of Parkinson's Disease  
Methods of treating Parkinson's Disease comprising administering compounds that up-regulate cystine-glutamate exchange (system Xc−) and/or increase glutathione levels in the brain cells. Preferred...
US20140066458 METHODS FOR TREATING VASCULAR LEAK SYNDROME  
Disclosed are methods for treating Vascular Leak Syndrome. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, inter alia, sepsis, lupus, irritable bowel...
US20130331386 METHODS FOR TREATING VASCULAR LEAK SYNDROME  
Disclosed are methods for treating Vascular Leak Syndrome. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, inter alia, sepsis, lupus, irritable bowel...
US20140294804 METHODS OF TREATING PAIN  
The invention relates to methods for treating pain disorders including neuropathic and inflammatory pain and to methods to reduce or eliminate nociceptive tolerance induced by opiate analgesic use...
US20120129847 COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES  
Disclosed are methods for the treatment of diseases or conditions of the eye, especially retinopathies, ocular edema and ocular neovascularization. Non-limiting examples of these diseases or...
US20110065761 METHODS OF TREATING NERVE-RELATED VISION DISORDERS  
This invention provides reagents and methods for delivering insulin, insulinomimetic agents, and the like to a vertebrate eye via subconjunctival routes, sub-Tenon's routes, or intravitreal routes...
US20140023615 THERMO-SENSITIVE, MUCOADHESIVE OR DERMOADHESIVE, AND PENETRATION-ENHANCING FORMULATIONS FOR TOPICAL DELIVERY OF THERAPEUTICS  
The present invention provides thermo-sensitive, mucoadhesive biopolymer formulations that enhance the penetration of therapeutics across the skin or mucosal surfaces. In a preferred embodiment,...
US20110135716 DELIVERY OF H2 ANTAGONISTS  
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist...
US20140364461 METHOD OF TREATING DERMATOLOGICAL DISORDERS  
A method of treating a dermatological disorder in a subject includes the step of administering a therapeutically effective amount of at least one PPARγ agonist or derivative thereof to the subject.
US20150005352 REACTIVE OXYGEN SPECIES-BASED PRODRUGS  
Provided herein are ROS-sensitive prodrug compositions and methods of treating ROS-associated diseases by administering the ROS-sensitive prodrug compositions.
US20090298745 Treatment of Diabetes with Glycogen Phosphorylase Inhibitors  
The invention provides a method of treatment of diabetes, particularly type II diabetes, or a diabetes related condition, comprising night time dosing of an inhibitor of glycogen phosphorylase,...
US20110251216 COMPOSITIONS AND METHODS FOR INHIBITING EZH2  
The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target EZH2 expression in cancer (e.g.,...
US20130261092 METHOD OF SYNERGISTICALLY ENHANCING THE THERAPEUTIC EFFICACY AND SAFETY OF MEDICATION THROUGH A COMBINATION THERAPY  
The present invention provides combinations, for treatment of subjects suffering from or at high risk of developing diseases and disorders involving expression of peroxisome proliferator-activated...
US20130005718 COMPOSITIONS AND METHODS OF TREATING CHRONIC PAIN BY ADMINISTERING PROPOFOL DERIVATIVES  
Compositions and methods for managing or treating chronic pain are provided. More particularly, methods are provided for managing or treating chronic pain by administering to a patient in need...
US20100305175 PHARMACEUTICAL LATRUNCULIN FORMULATIONS  
The present invention relates to an aqueous pharmaceutical formulation comprising at least one latrunculin and the formulation does not contain a substantial amount of dimethyl sulfoxide. In one...
US20120315303 METHODS AND INTRAVASCULAR TREATMENT DEVICES USING PACLITAXEL FOR TREATMENT OF ATHEROSCLEROSIS  
Methods and intravascular treatment devices for treating atherosclerosis are provided.
US20110293556 TREATMENT OF INSULIN RESISTANCE/METABOLIC SYNDROME TO ALLEVIATE THE RISKS OF DEMENTIA  
This invention relates to Applicant's discovery that Metabolic Syndrome , a cluster of disorders stemming from a resistance to insulin, contributes directly to dementia, particularly Alzheimer's...
US20090099238 USE OF A PPAR-ALPHA AGONIST TO TREAT PATIENTS SUFFERING FROM WEIGHT GAIN ASSOCIATED WITH A PPAR-GAMMA AGONIST TREATMENT  
The present invention relates to the use of a pparα agonist to treat patients suffering from weight gain associated with a pparγ agonist treatment.
US20120046242 MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY  
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant...
US20140335170 Reduced Mass Metformin Formulations  
The present invention relates to metformin extended release (XR) formulations with improved compactability to provide reduced mass tablets, granulations, and capsules.
US20120294936 REDUCED MASS METFORMIN FORMULATIONS  
The present invention relates to metformin extended release (XR) formulations with improved compactability to provide reduced mass tablets, granulations, and capsules.
US20130101553 INDUCING INACTIVATION OF FIBROGENIC MYOFIBROBLASTS  
Provided are methods of treating fibrotic conditions in a subject and diagnostic methods for determining fibrosis and appropriate treatments for the fibrosis by the identification of specific...
US20120322728 PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF DIABETES MELLITUS AND OTHER METABOLIC DISEASES  
The present invention relates to thiazolidinedione analogues and pharmaceutical compositions that are useful for treating and/or preventing diabetes mellitis, optionally in combination with a...
US20140206693 COMPOSITIONS AND METHODS FOR TREATING COLON CANCER  
Certain embodiments are directed to methods of treating a pathophysiological state or symptoms thereof resulting from aldose reductase-mediated signaling in a cytotoxic pathway using an aldose...
US20110172234 METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS  
This invention describes a series of methods and compositions for prevention and treatment of diseases such as cancer. One aspect of the invention describes small molecule-based drugs that can be...
US20130345268 Methods and Compositions for the Treatment of RAS Associated Disorders  
The instant disclosure relates to compositions that may be useful as therapeutic agents for the treatment of disorders associated or caused by Ras deregulation or dysregulation, for example,...
US20120302581 Methods and Compositions for the Treatment of RAS Associated Disorders  
The instant disclosure relates to compositions that may be useful as therapeutic agents for the treatment of disorders associated or caused by Ras deregulation or dysregulation, for example,...
US20060122174 Antiviral treatment  
A diuretic, e.g. loop diuretic or thiazide, or a sulphylurea is useful in the treatment of DNA viral infections.
US20120101067 METHODS FOR ENHANCING HEMATOPOIETIC PROGENITOR CELL ENGRAFTMENT  
Described herein are methods for improving engraftment of hematopoietic cells in an individual following hematopoietic progenitor cell transplantation (e.g., via bone marrow or cord blood...
US20130281414 THIAZOLIDINEDIONE ANALOGUES  
The present invention relates to thiazolidinedione analogues that are useful for treating liver afflictions such as nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH).
US20120129896 THIAZOLIDINEDIONE ANALOGUES FOR THE TREATMENT OF METABOLIC DISEASES  
The present invention relates to thiazolidinedione analogues that are useful for treating hypertension, diabetes, and inflammatory diseases.
US20150073025 METHOD FOR IDENTIFYING DISEASE RISK FACTORS  
Provided herein is a method for identifying a genetic variant that is associated with development of a condition of interest (e.g., Alzheimer's disease), and genetic variants so identified....
US20110223158 ASSOCIATION OF LEVELS OF HDL-CHOLESTEROL APOLIPOPROTEIN CIII WITH THE RISK OF CORONARY HEART DISEASE AND CARDIOVASCULAR EVENTS  
Presented herein are methods of diagnosing, assessing, and treating an individual at increased risk if developing coronary heart disease or cardiovascular event, based on the individual's level of...
US20110263545 HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS  
The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against...
US20140186295 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
Described herein are methods for the treatment of cancer (e.g. melanoma, lung cancer, or other cancers). The methods involve administrating to a subject in need thereof an agonist of the IL-9...
US20130225629 TARGETING PI3K/MTOR SIGNALLING AND NEUTROPHIL RECRUITMENT FOR TREATMENT OF ENTERITIS  
The presently disclosed subject matter generally relates to methods and compositions for treating enteritis. More particularly, the presently disclosed subject matter relates to methods and...
US20140140997 Methods of Treating Retroviral Infections in Felines  
Provided are methods for treating or reducing the likelihood of developing a retroviral infection in a feline, decreasing retroviral virion entry into a feline cell, decreasing retroviral virion...
US20150051161 Methods for the Detection of Advanced Glycation Endproducts and Markers for Disease  
The present invention provides compositions and methods for detecting carboxymethyl-lysine (CML) and circulating receptor for advanced glycation end (RAGE) products, and methods for correlating...
US20150111933 Deuterated Thiazolidinone Analogues as Agonists for Follicle Stimulating Hormone Receptor  
The present invention relates to deuterated thiazolidinone analogues as agonists for follicle stimulating hormone receptor and their use for treating fertility disorders.
US20110275558 LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS  
The present invention relates to the field of medical treatments for diseases and disorders. More specifically, the present invention relates to the use of the lanthionine synthetase component...
US20130253007 Compounds That Modulate Oxidative Stress  
The present invention provides methods of identifying compounds that selectively induce an oxidative stress response in a biological sample. The present invention further provides methods of...
US20100256204 MOLD-RESISTANT WALLBOARD  
Wallboard and facing paper that provides increased mold resistance at lower biocide loadings. The biocide is: (a) an n-alkyl isothiazolinone such as octylisothiazolinone (OIT), a monohalo and...
US20120264771 Method for Treating Androgen Receptor Positive Cancers  
Provided is a method of inhibiting growth of androgen receptor positive cancer cells. The method entails administering to an individual diagnosed with or suspected of having an androgen receptor...