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US20110092532 |
APOMORPHINE PHARMACEUTICAL DOSAGE SECURITY SYSTEM
An apomorphine pharmaceutical dosage security system embodied in multiple dosage forms including oral dosage forms, transdermal delivery patches, nasal delivery forms, and transdermal dosage... |
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US20130345164 |
TREATMENTS FOR CELLULAR PROLIFERATIVE DISORDERS AND IDENTIFICATION THEREOF
This invention concerns methods of identifying treatments for treating various disorders and related computer products and systems. Also disclosed are methods for treating cellular proliferative... |
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US20120041015 |
METHOD AND COMPOSITION FOR TREATING NODULOCYSTIC AND CONGLOBATE ACNE VULGARIS
Methods and compositions are described for the treatment of very severe acne vulgaris, including nodulocystic acne and conglobate acne. Compounds which inhibit either or both type 1 and type 2... |
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US20140037710 |
METHOD FOR PRODUCING PATCH, AND PATCH
A method for producing a patch including a support layer and an adhesive layer, comprising the step of forming the adhesive layer with use of an adhesive layer composition obtained by mixing an... |
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US20130231311 |
NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,... |
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US20140309247 |
Systems And Methods For Detecting Scalp Follicular Inflammation In Humans
Methods, processes, systems, and apparatuses are disclosed for detecting biomarkers associated with the inflammation response in the pilosebaceous unit of the human scalp using plucked human hair... |
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US20110150946 |
Transdermal Delivery of Apomorphine Using Microneedles
The present invention relates generally to methods for transdermal delivery of a therapeutically effective amount of apomorphine using microneedles. The invention also provides methods for... |
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US20120316111 |
BMP-2 Upregulating Compounds For Healing Bone Tissue And Screening Methods For Selecting Such Compounds
The present disclosure relates to a method to stimulate endogenous BMP-2 up-regulation in a subject which method comprises administering to a subject an effective amount of one or more of the... |
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US20130345230 |
METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting)... |
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US20120264808 |
METHODS AND COMPOSITIONS FOR MODULATING CALCIUM CHANNELS
The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting)... |
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US20120264766 |
PSEUDOBASE BENZO[C]PHENANTRIDINES WITH IMPROVED EFFICACY, STABILITY AND SAFETY
Pseudobase benzo[c]phenanthridines and the pharmaceutically acceptable salts thereof of Formula I are provided herein. The variables R, R1, R2, R3, and R4 are defined herein. Certain pseudobase... |
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US20130252983 |
ACTIVATING PHOSPHORYLATION SITE ON GLUTAMINASE C
A method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting activating phosphorylation of glutaminase C under conditions... |
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US20150216859 |
SUBLINGUAL APOMORPHINE
The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith. |
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US20110111011 |
SUBLINGUAL APOMORPHINE
The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith. |
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US20110190332 |
DOPAMINE RECEPTOR LIGANDS WITH ENHANCED DURATION OF ACTION
Trans-hexahydrobenzoaphenanthridines of the formula (I) wherein X, Y, R1, R2, R3, R4, R5, R6, and R7 are as defined herein, are disclosed. Pharmaceutical formulations including such compounds, and... |
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US20120034171 |
ABUSE-PROOFED DOSAGE FORM
The invention relates to a dosage form that is thermoshaped without being extruded and that is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking... |
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US20120220610 |
INHIBITIONS OF GLUTAMINASE C
The present invention relates to a method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting glutaminase C activity in the... |
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US20130324508 |
BIOMARKER FOR PROSTATE CANCER AND METHOD OF USING THE SAME
The present invention relates to a biomarker for characterizing prostate cancer and method of using the same. More particularly, the invention relates to method of using a membrane-associated C... |
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US20150119324 |
METHODS OF DELIVERING PHARMACEUTICAL AGENTS
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include... |
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US20140256627 |
METHODS OF DELIVERING PHARMACEUTICAL AGENTS
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include... |
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US20140315808 |
INHIBITION OF THE RENIN-ANGIOTENSIN SYSTEM FOR THE TREATMENT OF RENAL, VASCULAR AND CARTILAGE PATHOLOGY
A method of treating a disease or condition in which up-regulating GAGs is therapeutically beneficial is disclosed. The method comprises locally administering to a subject a therapeutically... |
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US20150125389 |
HALOGENATED COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE
Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R5, X1, X2, X3 and X4 are as defined herein, and wherein... |
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US20110158983 |
COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any... |
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US20130217685 |
COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR
The invention relates to compositions and methods for inhibiting RNA binding proteins (e.g., MEX-3, MEX-5 and POS-1), as well as methods for treating and preventing disorders associated with... |
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US20140194450 |
TOPICAL TREATMENT FOR CHEMOTHERAPY INDUCED EYELASH LOSS OR HYPOTRICHOSIS USING PROSTAMIDE F2 ALPHA AGONISTS
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of... |
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US20130131097 |
TOPICAL TREATMENT FOR CHEMOTHERAPY INDUCED EYELASH LOSS OR HYPOTRICHOSIS USING PROSTAMIDE F2 ALPHA AGONISTS
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of... |
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US20120004223 |
COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS
The present technology relates to compounds of Formulas (V) and (VI) and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia,... |
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US20130023498 |
MicroRNA Modulators and Method for Identifying and Using the Same
The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is... |
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US20120010177 |
MicroRNA Modulators and Method for Identifying And Using The Same
The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is... |
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US20110244033 |
TAMSULOSIN PELLETS FOR FIXED DOSE COMBINATION
The invention relates to a population of tamsulosin-comprising pellets for oral administration of a combination dosage form containing physically separated a tamsulosin dose in the form of the... |
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US20150044284 |
DOSAGE FORM COMPRISING A STEROID 5-ALPHA-REDUCTASE INHIBITOR AND AN ALPHA BLOCKER, PROCESS FOR PREPARING OF A DOSAGE FORM, USE OF DOSAGE FORM, METHOD FOR THE TREATMENT OR PROPHYLAXIS OF A DISEASE OR CONDITION MEDIATED BY ANDROGEN
The present invention describes new and improved dosage forms containing a steroid 5-alpha-reductase inhibitor, in combination with an alpha blocker, for the treatment or prophylaxis of an... |
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US20130190321 |
METHODS AND COMPOSITIONS RELATING TO PROLIFERATIVE DISORDERS OF THE PROSTATE
Methods and kits for aiding in detection, assessment and treatment of a proliferative disorder of the prostate gland in a subject are provided according to aspects of the present invention which... |
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US20150151029 |
IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST
The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial.... |
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US20120258161 |
IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST
The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial.... |
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US20110269754 |
COMPOUNDS AND COMPOSITIONS FOR REDUCING LIPID LEVELS
Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia,... |
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US20140309185 |
Inhibiting G Protein Coupled Receptor 6 Kinase Polypeptides
This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies,... |
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US20150011516 |
PHARMACEUTICAL COMPOSITIONS WHICH INHIBIT FKBP52-MEDIATED REGULATION OF ANDROGEN RECEPTOR FUNCTION AND METHODS OF USING SAME
Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain, otherwise known as FKBP52 Targeting... |
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US20120283215 |
PHARMACEUTICAL COMPOSITIONS WHICH INHIBIT FKBP52-MEDIATED REGULATION OF ANDROGEN RECEPTOR FUNCTION AND METHODS OF USING SAME
Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain, otherwise known as FKBP52 Targeting... |
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US20130101514 |
COMPOSITIONS AND METHODS FOR TREATING NEPHROPATHY
Activated fatty acids, pharmaceutical composition compositions including activated fatty acids, methods for using activated fatty acids to treat nephropathy, and methods for preparing activated... |
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US20110092533 |
COMPOUNDS FOR BINDING TO ER ALPHA/BETA AND GPR30, METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS AND IDENTIFICATION THEREOF
The current invention is in the field of molecular biology/pharmacology and provides compounds which modulate the effects of GPR30 as well as the classical estrogen receptors alpha and beta (ERα... |
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US20150198613 |
SOLUBLE MANF IN PANCREATIC BETA-CELL DISORDERS
The invention provides, in part, methods for diagnosing a pancreatic β-cell disorder, predicting a subject's risk of developing a pancreatic β-cell disorder, monitoring pancreatic β-cell function... |
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US20070015763 |
Treatment of psychosis associated with parkinson's disease and subcortical dementias using a combination of an atypical antipsychotic with a dopamine agonist
This invention relates to combinations of an atypical antipsychotic, for example ziprasidone, and a dopamine agonist, kits containing such combinations, pharmaceutical compositions comprising such... |
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US20120115891 |
METHOD FOR THE INDUCTION OF A REWARD RESPONSE BY MODULATION OF DOPAMINERGIC SYSTEMS IN THE CENTRAL NERVOUS SYSTEM
A method of modulating the dopaminergic system of the central nervous system comprising administering to a subject a dopamine precursor and/or a dopamine agonist in an amount effective to induce a... |
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US20120244097 |
REVERSELY THERMO-REVERSIBLE HYDROGEL COMPOSITIONS
A reversely thermo-reversible hydrogel composition comprising a water soluble block copolymer comprising at least two blocks of polyethylene oxide and at least one block of polypropylene oxide,... |
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US20130251647 |
LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF
The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators... |
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US20100324079 |
Medicament for prophylaxis and treatment of Alzheimer disease
A medicament effective for inhibiting onset of Alzheimer disease via intracellular aggregation mechanism is provided. A medicament for prophylaxis and treatment of Alzheimer disease comprising as... |
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US20070254906 |
Method of Administration of Dopamine Receptor Agonists
Methods for treating a patient having pulmonary edema are described. The methods include administering to the lung endobronchial space of the airways of the patient an effective amount of a... |
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US20140323420 |
REDUCING TRANSMISSION OF SEXUALLY TRANSMITTED INFECTIONS
Described herein are compositions and methods for treating or preventing a sexually transmitted infection in a subject |
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US20080300225 |
PESTICIDAL FORMULATION CONTAINING OXYMATRINE OR MATRINE
Compositions and methods are provided for a water-soluble insecticidal or pesticidal comprising at least one alkaloid, particularly at least one tetracyclo-quinolizindine alkaloid derived from... |
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US20130072463 |
PHARMACEUTICAL COMPOSITIONS USEFUL FOR PREVENTING AND TREATING CANCER
Disclosed is a method of treating a cancer on a mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of a compound |