AcclaimIP-ad

Match Document Document Title
US20140073604 Ladder-Frame Polyether Conjugates  
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and...
US20120077778 Ladder-Frame Polyether Conjugates  
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and...
US20150224104 METHODS FOR THE TREATMENT OF LOCALLY ADVANCED BREAST CANCER  
Provided herein are methods of treating, preventing and/or managing locally advanced breast cancer, including inflammatory breast cancer, which comprise administering to a patient one or more...
US20130345164 TREATMENTS FOR CELLULAR PROLIFERATIVE DISORDERS AND IDENTIFICATION THEREOF  
This invention concerns methods of identifying treatments for treating various disorders and related computer products and systems. Also disclosed are methods for treating cellular proliferative...
US20140363522 Compositions and Methods for Treating and/or Preventing Cancer by Inhibiting Fatty Acid Binding Proteins  
The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins.
US20130121912 MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
US20130274281 METHODS OF TREATING METASTATIC BREAST CANCER WITH 4-IODO-3-NITROBENZAMIDE AND IRINOTECAN  
Provided herein are methods, compositions and kits for the treatment of locally advanced or metastatic breast cancer or breast cancer brain metastases. The method comprises administration of...
US20110171323 METHODS AND KITS TO PREDICT PROGNOSTIC AND THERAPEUTIC OUTCOME IN SMALL CELL LUNG CANCER  
Disclosed herein are methods used in the identification of cancer patients likely or unlikely to respond to systemic chemotherapy, methods of treating cancer patients based upon the...
US20150254433 Methods and Models for Determining Likelihood of Cancer Drug Treatment Success Utilizing Predictor Biomarkers, and Methods of Diagnosing and Treating Cancer Using the Biomarkers  
A method of identifying one or more biomarkers associated with one or more drugs effective to stop or repress proliferation of cancer cells, and a system for predicting effectiveness of the same....
US20150202153 LIPOSOMAL DRUG DELIVERY SYSTEM  
The invention relates to a drug delivery system, particularly to a liposomal drug delivery system. Most particularly the invention relates to a liposomal drug delivery system for the release of at...
US20130336969 USE OF OLFACTOMEDIN-4 PROTEIN (OLFM4) IN COLORECTAL CANCER DIAGNOSIS  
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting...
US20150182521 METHODS FOR TREATING PANCREATIC CANCER USING COMBINATION THERAPIES COMPRISING LIPOSOMAL IRINOTECAN  
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the...
US20120134986 Methods of Prognosis for Non-Hodgkin Lymphoma  
Measurement of a single gene expressed by tumor cells (LMO2) and a single gene expressed by the immune microenvironment (TNFRSF9), which determination may be referred to herein as a two gene score...
US20110123448 OIL BODY CARRIERS, USES IN TARGET THERAPY AND/OR DETECTION OF THE SAME, AND FUSION PROTEINS COMPRISED THEREIN  
An oil body carrier, its uses in target therapy and/or detection, and a fusion protein comprised therein are provided. The oil body carrier comprises: a) the fusion protein, comprising an oil body...
US20140314750 Six-Gene Biomarker of Survival and Response to Platinum Based Chemotherapy in Serious Ovarian Cancer Patients  
Described herein are methods of predicting the risk of developing ovarian cancer recurrence of a subject comprising the steps of detecting the expression levels of at least four of the six genes...
US20140234295 ISOFLAVONOID COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER  
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in...
US20130178493 USE OF 14,15-DIHYDRO-20,21-DINOREBURNAMENIN-14-OL FOR THE TREATMENT AND/OR PREVENTION OF SERIOUS DEPRESSION AND SLEEP/WAKING CYCLE DISORDERS  
The invention relates to a novel therapeutic use of 14,15-dihydro-20,21-dinoreburnamenin-14-ol for the treatment of serious depression in humans, particularly for the treatment of a patients...
US20110201636 USE OF 14,15-DIHYDRO-20,21-DINOREBURNAMENIN-14-OL FOR THE TREATMENT AND/OR PREVENTION OF SERIOUS DEPRESSION AND SLEEP/WAKING CYCLE DISORDERS  
The invention relates to a novel therapeutic use of 14,15-dihydro-20,21-dinoreburnamenin-14-ol for the treatment of serious depression in humans, particularly for the treatment of a patients...
US20120129880 METHOD FOR DETERMINING SENSITIVITY TO IRINOTECAN AND USE THEREOF  
To provide a method for determining the sensitivity of a patient to irinotecan, SN-38, and/or a salt thereof, which method can determine the therapeutic response of the patient and to provide a...
US20110136751 Use of Polyphenols in the Treatment of Cancer  
The present invention relates to polyphenol compounds, compositions thereof, and methods for treating or preventing cancer in a subject, the methods comprising co-administering to a subject an...
US20150258085 Treating Tumors of the Central Nervous System  
A synergistic therapeutic effect is obtained in CNS cancer patients treated concomitantly with a first antineoplastic agent and a second antineoplastic agent, wherein one or both antineoplastic...
US20110123488 Method of Treatment for Cancers Associated with Elevated HER2 Levels  
Novel methods of treating proliferative disorders characterized by elevated Her-2, and the patient is then administered an effective amount of an HSP90 inhibitor.
US20120141603 METHODS AND COMPOSITIONS FOR LUNG CANCER PROGNOSIS  
Disclosed herein are methods and materials for prognosing survival of lung cancer patients, the methods comprising the detection of gains and losses of minimal common regions and/or genes...
US20130029918 METHODS FOR REDUCING VEIN IRRITATION  
The present invention provides compositions for delivering highly water-soluble drugs (such as vinca alkaloids) and methods of using such compositions.
US20120128667 PENTAMIDINE COMBINATIONS FOR TREATING CANCER  
The present invention relates to the treatment of cancer, e.g., ovarian cancer, breast cancer, pancreatic cancer or colon cancer, with pentamidine and (a) oxaliplatin, (b) gemcitabine, (c) taxol,...
US20110268803 LUNG TARGETING DUAL DRUG DELIVERY SYSTEM  
The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments...
US20110035232 METHODS OF TREATING HEPATIC ENCEPHALOPATHY  
Treatment of hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also...
US20100305070 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS  
The disclosure relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express cytochrome...
US20130023488 METHODS AND COMPOUNDS FOR REDUCING INTRACELLULAR LIPID STORAGE  
Compounds and compositions for reducing intracellular lipid accumulation in a cell are described herein. These compounds are useful for the treatment and prevention of lipid/glycogen disorders, as...
US20120201822 TUMOR TREATMENT  
The invention concerns an improved method for treating tumor, including cancer, which combines the administration of a chemotherapeutic agent and an antagonist of a gene product the expression of...
US20150087668 Methods for Treating Humans Having Brain Cancer  
Among other things, a method of treating a human having brain cancer is, the method comprising administering via a non-continuous dosing regimen to the human having brain cancer, a therapeutically...
US20120202840 Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases  
Provided are methods for treating a hematological malignancy comprising administering an effective amount of flubendazole alone or in combination with a vinca alkaloid. Also provided are...
US20130266508 THERMOSENSITIVE HYDROGEL FOR COATING RADIOISOTOPE AND CHEMOTHERAPEUTIC AGENT TO TREAT CANCER AND METHOD FOR PREPARING THE SAME  
A thermosensitive hydrogel for coating radioisotopes and chemotherapeutic agents to treat cancer and a method for preparing the same are revealed. The anticancer drugs such as radiopharmaceuticals...
US20120003297 COMPOSITIONS AND METHODS FOR TREATING LYMPHOMA  
This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of...
US20110311648 Novel Methods for the Treatment of Cancer  
Compositions and methods for the treatment of malignancy and chronic viral infection are disclosed.
US20140037620 Methods of Treating Breast Cancer with Gemcitabine Therapy  
The application describes methods for predicting overall survival in subjects with breast cancer. The application also describes for screening subjects with breast cancer to determine if the...
US20120251630 REMISSION THERAPY OF CANCER WITH ISOFLAVONOIDS  
Provided herein is a method of reducing incidences of cancer recurrence. The method involves administering to an individual in cancer remission an isoflavonoid. In specific instances, the treated...
US20120164211 COMPOSITIONS AND METHODS FOR TREATING LYMPHOMA  
The present invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of leukemias, including acute lymphoblastic...
US20110014204 Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2  
The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed...
US20120282172 TARGETED DELIVERY TO HUMAN DISEASES AND DISORDERS  
The present invention provides a system presenting site-specific accumulation through a ligand that specifically targets a receptor overexpressed on the surface of specific cells within a target...
US20120220613 METHOD FOR DETERMINING SENSITIVITY TO AN ANTICANCER AGENT  
To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. The marker for determining sensitivity to an...
US20140348854 HE4 Based Therapy For Malignant Disease  
The invention provides compositions and methods for utilizing human epididymal secretory protein E4 (HE4) in the prevention and treatment of cancer and other human diseases.
US20150165026 SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF  
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at...
US20120231090 MOLECULAR BIOMARKER SET FOR EARLY DETECTION OF OVARIAN CANCER  
Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the...
US20150065945 SPINAL NEUROMODULATION AND ASSOCIATED SYSTEMS AND METHODS  
Methods for treating a patient using therapeutic spinal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to...
US20150093328 COMPOSITIONS AND METHODS FOR NON-INVASIVE IMAGING  
The present invention relates to a novel composition useful in targeted diagnostic and/or therapy of a target site, such as cancerous tissue. The composition and methods disclosed herein find...
US20130295198 METHODS OF SCREENING CHEMOTHERAPEUTIC AGENTS AND TREATING CANCER  
Methods for selecting chemotherapeutic agents for treating a cancer are provided that include the steps of providing a cancer cell sample having a population of bulk cancer cells and a population...
US20110158983 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES  
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any...
US20150141342 BLOOD BORNE miRNA SIGNATURE FOR THE ACCURATE DIAGNOSIS OF PANCREATIC DUCTAL ADENOCARCINOMA  
The differential expression of select miRNA in plasma and bile among patients with PDAC, chronic pancreatitis (CP), and controls were measured. Patients (n=215) with treatment-naïve PDAC (n=77),...
US20140134280 EXTRACTS OF CYNANCHUM SP. AND ACTIVE INGREDIENTS CONTAINED THEREIN IN USE OF ARTHRITIS TREATMENT  
An extract of Cynanchum sp. in use of arthritis treatment is provided. The extract of Cynanchum sp. and an active ingredient contained therein, antofine, are applicable to a method, pharmaceutical...