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US20160022574 |
NON-MUCOADHESIVE FILM DOSAGE FORMS
Orally disintegrating film dosage forms for delivering active pharmaceutical agents, methods of formulating the dosage forms to retard absorption through the oral mucosa, and methods of using the... |
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US20140093513 |
METHODS OF LOWERING PROPROTEIN CONVERSATE SUBTILISIN/KEXIN TYPE 9 (PCSK9)
The invention relates to new methods of modulating cholesterol by inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9) with fatty acid derivatives; and new methods for treating or... |
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US20120238940 |
CYCLOOXYGENASE INHIBITOR AND CALCIUM CHANNEL ANTAGONIST COMPOSITIONS AND METHODS FOR USE IN UROLOGICAL PROCEDURES
Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional,... |
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US20110071176 |
PHARMACEUTICAL COMPOSITION COMPRISING OMEGA-3 FATTY ACID AND HYDROXY-DERIVATIVE OF A STATIN AND METHODS OF USING SAME
In various embodiments, the present invention provides compositions and methods for treating and/or preventing a cardiovascular-related disease in subject in need thereof. |
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US20100196517 |
TOPICAL DELIVERY OF A NITRIC OXIDE DONOR TO IMPROVE BODY AND SKIN APPEARANCE
This invention generally relates to improvement of the body and skin appearance, for example enhancing the appearance of sagging, wrinkled, or cellulite-afflicted areas of the skin and body,... |
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US20100190753 |
Methods and Compositions for Treating Amyloid-Related Diseases
Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease. |
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US20090221620 |
GENTIC POLYMORPHISMS ASSOCIATED WITH STROKE, METHODS OF DETECTION AND USES THEREOF
The present invention provides compositions and methods based on genetic polymorphisms that are associated with vascular diseases such as stroke. In particular, the present invention relates to... |
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US20080015209 |
COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and... |
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US20050267135 |
Combinations comprising antimuscarinic agents and PDE4 inhibitors
Combinations comprising (a) a PDE4 inhibitor and (b) an antagonist of M3 muscarinic receptors which is 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)
-1-azoniabicyclo[2.2.2]octane,... |
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US20140179722 |
Antiperspirant and Deodorant Compositions
The present application relates to personal care compositions comprising perfumes and non-sulfur-based perfume raw materials, and methods for making and using the personal care compositions to... |
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US20130303558 |
GENETIC POLYMORPHISMS ASSOCIATED WITH STROKE, METHODS OF DETECTION AND USES THEREOF
The present invention provides compositions and methods based on genetic polymorphisms that are associated with vascular diseases such as stroke. In particular, the present invention relates to... |
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US20110294767 |
BILE ACID RECYCLING INHIBITORS AND SATIOGENS FOR TREATMENT OF DIABETES, OBESITY, AND INFLAMMATORY GASTROINTESTINAL CONDITIONS
Provided herein are methods of utilizing bile acid transport inhibitors and/or enteroendocrine peptide enhancing agents for the treatment of obesity, diabetes, and inflammatory gastrointestinal... |
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US20090131325 |
ABUSE-RESISTANT AMPHETAMINE PRODRUGS
The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for... |
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US20080058360 |
Soluble CD40L (CD 154) as a prognostic marker of atherosclerotic diseases
This invention involves the new use of a diagnostic test to determine the risk of atherosclerotic diseases such as myocardial infarction and stroke, particularly among individuals with no signs or... |
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US20050130906 |
Amelioration of macular degeneration and other ophthalmic diseases
Methods for the treatment or prevention of a number of ocular diseases or disorders are disclosed. In particular, methods are disclosed for the amelioration of macular degeneration, diabetic... |
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US20150335787 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable pouch formed from at least one sheet of bioremodelable extracellular matrix (ECM) material, the pouch including an internal region that is configured to receive a medical device,... |
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US20130012487 |
1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS
1-Phenyl-2-pyridinyl alkyl alcohol compounds are effective as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and may be used to prevent and/or treat certain diseases or conditions. |
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US20120172392 |
AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES
Compositions and methods are disclosed for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1). The compounds disclosed are amine-containing... |
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US20090232886 |
ORAL DOSAGE COMBINATION PHARMACEUTICAL PACKAGING
Pharmaceutical fixed dose combination products are formed by merging a fixed dose of a first pharmaceutical formulation from primary module, with a fixed dose of a second pharmaceutical... |
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US20150216182 |
COMPOSITIONS AND METHODS OF THE ATTRACTION AND REPULSION OF INSECTS
The present invention provides insect attractants and repellents as well as methods of trapping and/or altering the behavioral patterns of vector pests such as mosquitoes and other hematophagous... |
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US20080064711 |
Composition for treating oral cavity and Mucousal infections
The present invention provides a composition of matter for treating oral cavity infections and mucosal infections, said composition comprising: at least one anti-microbial drug; and at least one... |
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US20070293495 |
BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS
Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of... |
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US20130115294 |
STABLE LIQUID OILY READY-TO-USE FORMULATIONS, PREPARATION THEREOF AND USE THEREOF
The present invention relates to a stable liquid oily ready-to-use formulation comprising an active pharmaceutical ingredient, which has hydrophobic and/or lipophilic properties and/or which... |
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US20070196465 |
Treatment with dihydropyridine calcium channel blockers and omega-3 fatty acids and a combination product thereof
Combinations of one or more dihydropyridine calcium channel blockers with mixtures of omega-3 fatty acids, methods of administering such combinations, and unit dosages of such combinations. |
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US20160151322 |
METALLO-B-LACTAMASE INHIBITORS
A new metallo-β-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of β-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid... |
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US20150307426 |
INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS
Processes for making and using compounds of formula (I): wherein R1, R2, R3, R4a, R4b, R5 and R6 are defined herein, as well as other indene derivatives are disclosed herein. These compounds are... |
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US20090264453 |
GENETIC POLYMORPHISMS ASSOCIATED WITH CORONARY HEART DISEASE, METHODS OF DETECTION AND USES THEREOF
The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease, and in particular MI, and response to drug treatment. In particular, the... |
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US20090258889 |
PESTICIDAL COMPOSITIONS
The present disclosure relates to pesticidal compositions and to methods for controlling pests such as insects and other arthropods. More particularly, the disclosure relates to a pesticidal... |
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US20090131367 |
Combinations of HDAC Inhibitors and Proteasome Inhibitors
Provided herein are pharmaceutical agents, pharmaceutical compositions, methods of treatment, treatment regimens and kits for the treatment of cancer. |
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US20080169215 |
Cosmetic compositions
The present invention relates to a composition comprising from about 0.1% to about 10% of a hydrophobic structuring agent; from about 0.1% to about 10% of a hydrophilic surfactant; from about... |
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US20130245053 |
Pesticidal Compositions
The present disclosure relates to pesticidal compositions and to methods for controlling pests such as insects and other arthropods. More particularly, the disclosure relates to a pesticidal... |
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US20130137648 |
DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS
Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme. |
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US20110144075 |
DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS
Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme. |
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US20100119482 |
Treatment of Conditions Through Modulation of the Autonomic Nervous System During at Least One Predetermined Menstrual Cycle Phase
Methods are provided for treating a subject for a condition. In accordance with the subject methods, at least a portion of a subject's autonomic nervous system is modulated during at least one... |
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US20070015737 |
Compounds for inhibiting diseases and preparing cells for transplantation
Methods and compositions which are useful in the treatment of amyloidosis. In particular, methods and compositions are provided for inhibiting, preventing and treating amyloid depositions, e.g. in... |
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US20120064160 |
Fibrate-statin Combinations with Reduced Fed-fasted Effects
This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the... |
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US20110245188 |
METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISEASES OR CONDITIONS
The present invention relates to methods and compositions of treating or preventing inflammatory diseases or conditions in a patient comprising administering to the patient a therapeutically... |
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US20100144677 |
METHOD FOR SCREENING AGENTS FOR THE TREATMENT OF DIABETES
A convenient screening tool and a convenient screening method for obtaining an agent for treating diabetes, a pharmaceutical composition for treating diabetes, and a process for manufacturing the... |
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US20090069623 |
METHODS AND COMPOSITIONS FOR TREATMENT OR PREVENTION OF RADIATION-INDUCED FIBROSIS
The present invention comprises methods and compositions for the treatment or prevention of radiation-induced fibrosis. Methods and compositions for the inhibition of CTGF are disclosed herein.... |
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US20090069361 |
METHODS OF TREATMENT USING (+)- ISOPROPYL 2-METHOXYETHYL 4-(2-CHLORO-3-CYANO-PHENYL)-1, 4-DIHYDRO-2, 6-DIMETHYL-PYRIDINE-3, 5-DICARBOXYLATE
The present invention relates to methods of treatment using the compound (+)-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridin
e-3,5-dicarboxylate, as a sole... |
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US20080015195 |
Novel Heteroaromatic Inhibitors of Fructose-1,6-Bisphosphatase
Novel FBPase inhibitors of the formula I and X are useful in the treatment of diabetes and other conditions associated with elevated blood glucose. |
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US20120172340 |
Compositions and Methods for Selectively Activating Human Sirtuins
Methods for identifying selective activators of SIRT5 and/or SIRT1 and methods for using these selective activators in the modulation of SIRT5 and/or SIRT1 are provided. |
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US20070258996 |
Antimicrobial compositions
An antimicrobial composition, including a synergistic combination of three or more potentiating agents as an active ingredient. Each of the three or more potentiating agents may be selected from... |
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US20070244141 |
COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and... |
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US20070191409 |
Compounds for inhibiting beta-amyloid production and methods of identifying the compounds
Provided are compounds useful for treating diseases associated with a cerebral accumulation of Alzheimer's amyloid, such as Alzheimer's disease. Also provided are methods for screening for such... |
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US20150320730 |
GPBP-1 inhibition and its therapeutic use
The present invention provides compositions including anti-tumor agents and inhibitors of Goodpasture antigen binding protein, p21, and ABCC7, and their use in treating cancer. |
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US20150322006 |
PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE
Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are... |
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US20080050432 |
Combined Pharmaceutical Formulation with Controlled-Release Comprising Dihydropyridine Calcium Channel Blockers and HMG-COA Reductase Inhibitors
The present invention relates to a combined pharmaceutical formulation, which is such designed that the release of each ingredient may be controlled to a predetermined release rate by applying the... |
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US20050020593 |
Aryl-heteroaromatic compounds, compositions comprising them and use
A series of aryl-heteroaromatic compounds, compositions comprising them and use thereof are disclosed and claimed. The present invention relates in particular to novel aryl-heteroaromatic... |
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US20090156614 |
Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof
This invention provides new compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, prostate cancer, muscle wasting diseases and/or... |