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US20140099300 METHODS FOR PREDICTING AND IMPROVING THE SURVIVAL OF GASTRIC CANCER PATIENTS  
The present invention provides assays and methods for predicting the post-operative survival of a subject having an early stage gastric cancer after tumor surgery. The present invention also...
US20140142116 Method of Treatment or Prophylaxis of Inflammatory Pain  
A method of treatment, reversal and/or symptomatic relief of inflammatory pain, including hyperalgesia, thermal or mechanical allodynia, in vertebrate animals, particularly in human subjects,...
US20120264703 Methods And Compositions For The Treatment Of Anxiety Disorders, Including Post Traumatic Stress Disorder (PTSD) And Related Central Nervous System (CNS) Disorders.  
The present invention provides novel methods and formulations for treating anxiety disorders, including Post Traumatic Stress Disorder, in human subjects employing coordinate treatment using α and...
US20120315217 INVERSE AGONISTS AND NEUTRAL ANTAGONISTS FOR THE TSH RECEPTOR  
TSHR inverse agonists and neutral antagonists that are useful for treating Graves' orbitopathy, Graves' hyperthyroidism and/or thyroid cancer.
US20120178757 Method For The Prevention Of Cancer Metastasis  
A method is provided for the prevention of cancer metastasis in a patient comprising administering an adrenergic receptor antagonist to a patient in need thereof. The invention also includes an...
US20140228362 Method of Treatment or Prophylaxis  
The present invention is directed to methods and agents that are useful in the prevention and amelioration of signs and symptoms associated with neuropathic conditions. More particularly, the...
US20130296350 Method of Treatment or Prophylaxis  
The present invention is directed to methods and agents that are useful in the prevention and amelioration of signs and symptoms associated with neuropathic conditions. More particularly, the...
US20110318329 METHOD OF TREATMENT OR PROPHYLAXIS  
The present invention is directed to methods and agents that are useful in the prevention and amelioration of signs and symptoms associated with neuropathic conditions. More particularly, the...
US20120184504 "The Use of a PAR-1 Antagonist in Combination with a P2Y12 ADP Receptor Antagonist for Inhibition of Thrombosis"  
The treatment and prevention of thrombotic events are provided through co-administration of PAR-1 and the P2Y12 ADP receptor antagonists. Combined inhibition of the PAR-1 and the P2Y12 ADP...
US20140336142 Method For Treatment Of Macular Degeneration By Modulating P2Y12 or P2X7 Receptors  
Provided is a method of treating or preventing age-related macular degeneration (AMD) in a patient subject to, or symptomatic of the disease, wherein the method comprises restoring normal...
US20120264708 Method For Treatment Of Macular Degeneration By Modulating P2Y12 or P2X7 Receptors  
Provided is a method of treating or preventing age-related macular degeneration (AMD) in a patient subject to, or symptomatic of the disease, wherein the method comprises restoring normal...
US20130259858 Signature for Predicting Clinical Outcome in Human HER2+ Breast Cancer  
A method of predicting outcome in a subject with for example Her2+ (ERα−) breast cancer comprising: a. determining a HTICs expression signature comprising determining an expression level of 2 or...
US20120321615 Assay for Metastatic Colorectal Cancer  
Disclosed herein is a method for predicting the prognosis, the likelihood of metastasis in, or the desirability of administering an aggressive therapy to, a subject with colorectal cancer,...
US20110201633 ALFUZOSIN TABLETS AND SYNTHESIS  
A monolithic composition includes alfuzosin in a polymeric matrix adapted to release 13-33% of the alfuzosin within 2 hours, 40-60% of the alfuzosin within 7 hours, and greater than 80% of the...
US20120076770 Modulation of autophagy and and serotonin for treatment of multiple myeloma related diseases  
THE INVENTION RELATES TO compounds, proteins and methods of treatment therewith. Aspects of embodiments of the invention further relates to compounds and methods of treatment for bone, bone...
US20140170135 EGFR EXPRESSION IS ASSOCIATED WITH DECREASED BENEFIT FROM TRASTUZUMAB IN THE NCCTG N9831 TRIAL  
The subject invention provides a method for treating a patient having a tumor associated with HER2+ breast cancer comprising: measuring in a sample of the patient's tumor a level of expression of...
US20110312982 Cancer Treatment Method  
A method of treating cancer is described including administration of a 4-quinazolinamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the...
US20130012465 BIBW 2992 FOR USE IN THE TREATMENT OF TRIPLE NEGATIVE BREAST CANCER  
The present invention relates to a method of treating patients suffering from triple negative breast cancer comprising administration of an effective amount of the irreversible EGFR/HER1 and HER2...
US20130195870 ERBB3 Mutations In Cancer  
The present invention concerns somatic ErbB3 mutations in cancer including methods of identifying, diagnosing, and prognosing ErbB3 cancers, as well as methods of treating cancer, including...
US20110189173 PHOSPHORYLATED C-ErbB2 AS A SUPERIOR PREDICTIVE THERANOSTIC MARKER FOR THE DIAGNOSIS AND TREATMENT OF CANCER  
The present invention provides reliable methods to identify subsets of subjects with a cancer of epithelial origin characterized by a high level of phosphorylated c-erbB2 which does not correlate...
US20150190397 Treatment of Cancers Expressing p95 ErbB2  
The truncated ErbB2 receptor (p95ErbB2) is shown to differ from the full-length ErbB2 receptor in its association with other ErbB receptors. The truncated receptor preferentially associated with...
US20110020335 Treatment of Cancers Expressing p95 ErbB2  
The truncated ErbB2 receptor (p95ErbB2) is shown to differ from the full-length ErbB2 receptor in its association with other ErbB receptors. The truncated receptor preferentially associated with...
US20140080783 PHARMACEUTICAL COMBINATIONS FOR TREATMENT OF SPECIFIC CANCERS  
The present invention relates to the field of oncology and provides compositions and methods for treating specific cancers, including non small cell lung cancer, breast cancer, thyroid cancer,...
US20130216523 Methods for Facilitating Diagnosis, Prognosis and Treatment of Cancer by Detecting HER1 Expression  
Methods are provided for facilitating the diagnosis of subjects with HER1-activated cancers. In addition, method of treating subjects with a cancer characterized as having high levels of activated...
US20150232457 CRYSTALLINE FORMS OF AFATINIB DI-MALEATE  
Crystalline forms of Afatinib di-maleate are described in the present application and processes for their preparation. The present invention also includes pharmaceutical compositions of such...
US20100305070 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS  
The disclosure relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express cytochrome...
US20140135296 METHODS OF TREATING AUTOPHAGY-ASSOCIATED DISORDERS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS  
The invention provides methods of treating autophagy mediated diseases and disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the...
US20130131089 DOSAGE FORMS OF ELINOGREL AND METHODS OF INJECTABLE ADMINISTRATION THEREOF  
The present invention is concerned with a liquid delivery form of Elinogrel for the treatment of thrombosis which is notable for its improved dosage properties and stability. The dosage form is a...
US20140163050 Use of 1H-quinazoline-2,4-diones  
The invention concerns the use of competitive AMPA receptor antagonists for the treatment or prevention of photosensitive epilepsy.
US20130090346 Use of 1H-quinazoline-2,4-diones  
The invention concerns the use of competitive AMPA receptor antagonists for the treatment or prevention of photosensitive epilepsy.
US20110262437 USE OF ERBB4 AS A PROGNOSTIC AND THERAPEUTIC MARKER FOR MELANOMA  
It is disclosed herein that members of the protein tyrosine kinase (PTK) family are highly mutated in patients with melanoma. Described herein are novel somatic mutations in the ERBB4 gene that...
US20120282172 TARGETED DELIVERY TO HUMAN DISEASES AND DISORDERS  
The present invention provides a system presenting site-specific accumulation through a ligand that specifically targets a receptor overexpressed on the surface of specific cells within a target...
US20120052062 Methods for Treatment of Non-Small Cell Lung Cancer  
The present invention provides methods of treating non-small cell lung cancer by administering to a subject in need thereof a therapeutically effective amount of a...
US20110110933 ECTOPIC PREGNANCY TREATMENT  
The invention pertains to methods for treating ectopic pregnancy. More particularly, the present invention relates to methods for treating unruptured ectopic pregnancy using a non-surgical method...
US20140030254 SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE  
The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of...
US20110200597 SIGNAL PATHWAY ALTERATIONS AND DRUG TARGET ELEVATIONS IN PRIMARY METACHRONOUS METASTATIC COLORECTAL CANCER COMPARED TO NON-METASTATIC DISEASE  
The present invention relates to the identification and diagnostic use of biomarkers in primary colorectal cancer tumors whose activation level are predictive of the likelihood of the onset of...
US20110158983 COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGY THERAPIES  
In alternative embodiments, this invention provides compositions and methods for treating cancer or any condition caused by dysfunctional cells, side effects from treatments for cancer or any...
US20150023965 METHODS OF TREATING UROTHELIAL CARCINOMA  
Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.
US20130108697 MODIFIED RELEASE DOSAGE FORM  
There is provided a modified release dosage form comprising a core coated with a polymeric coat, said polymeric coat comprising one or more rate controlling polymers, said dosage form having a...
US20140112918 SYNERGISTIC PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK  
The present invention relates to a pharmaceutical combination for use in the treatment of squamous cell carcinoma, comprising a CDK inhibitor selected from the compounds of formula (I); or a...
US20150057335 NOVEL FUSION GENES IDENTIFIED IN LUNG CANCER  
[PROBLEMS] To identify mutations that can serve as indicators for predicting the effectiveness of drug treatments in cancers such as lung cancer; to provide a means for detecting said mutations;...
US20140018376 Use of 1H-Quinazoline-2,4-Diones  
The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of Rasmussen's encephalitis and/or certain forms of epilepsy.
US20130018062 Pain therapy with metabolism blocked antifolates  
The perception of pain precedes the manifestation of measurable and quantifiable clinical symptoms of most diseases. Pain is an early warning signal at the beginning of a physical abnormality. The...
US20120321637 COMBINATION CANCER THERAPY WITH HERV INHIBITION  
Embodiments are directed to compositions and methods related combination therapy with HERV inhibition.
US20150023953 METHOD OF TREATING CANCER  
Methods are provided for treating cancer in a patient in need thereof with a HER2 inhibitor, where such patients have certain polymorphisms in VEGFA, VEGFR or IGF1R.
US20130096145 Use of 1H-quinazoline-2,4-diones  
The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of spasticity.
US20120058201 METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION  
The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT...
US20140309184 METHODS AND COMPOSITIONS FOR THE TREATMENT OF OVARIAN CANCER  
Embodiments of the present disclosure relate to methods and compositions for treating a subject with ovarian cancer. Some embodiments include treating a subject with a particular combination of...
US20110300137 Use of lumefantrine and related compounds in the treatment of cancer  
The present application discloses the use of the anti-malarial drug lumefantrine and related compounds in the treatment of cancer.
US20130190321 METHODS AND COMPOSITIONS RELATING TO PROLIFERATIVE DISORDERS OF THE PROSTATE  
Methods and kits for aiding in detection, assessment and treatment of a proliferative disorder of the prostate gland in a subject are provided according to aspects of the present invention which...

Matches 1 - 50 out of 401 1 2 3 4 5 6 7 8 9 >