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US20060188472 HAS-active ingredient conjugates  
The invention relates to compounds comprising a conjugate of hydroxyalkyl starch (HAS) and an active agent, whereby the hydroxyalkyl starch is either directly covalently bonded to the active...
US20150093455 COMPOSITIONS AND METHODS FOR INCREASING TELOMERASE ACTIVITY  
The present invention relates to methods and compositions for increasing telomerase activity in cells. Such compositions include pharmaceutical, including topical, and nutraceutical formulations....
US20070166368 Protein-Stabilized Liposomal Formulations of Pharmaceutical Agents  
The present invention relates to protein stabilized liposomes. Specifically, the present invention discloses compositions and methods for protein stabilized liposomes, the creation of protein...
US20130324485 Method of Determining the Probability of a Therapeutic Response in Cancer Chemotherapy with Cardiac Glycoside  
A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment...
US20060287263 Methods and compositions for inducing antigen-specific immune responses  
Vaccine compositions comprising (a) an oligonucleotide, (b) and immune stimulating complex and (c) an antigen induce a strong interferon-gamma immune response. Both oligonucleotides containing...
US20050159366 Pharmaceutical compositions and treatment methods - 8  
The invention provides compositions comprising formula 1 steroids, e.g., 16α-bromo-3β-hydroxy-5α-androstan-17-one hemihydrate and one or more excipients, typically wherein the composition...
US20110152209 Core 2 GlcNAc-T Inhibitors  
The present invention relates to the use of known and novel compounds as inhibitors of UDP-GlcNAc:Galβ1,3GalNAc-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyl transferase (core 2 β1,6...
US20070173476 MODIFIED POLYNUCLEOTIDES FOR USE IN RNA INTERFERENCE  
Methods and compositions for performing RNA interference comprising a wide variety of stabilized siRNAs suitable for use in serum-containing media and for in vivo applications, such as therapeutic...
US20070155679 USE OF BRADYCARDIAC SUBSTANCES IN THE TREATMENT OF MYOCARDIAL DISEASES ASSOCIATED WITH HYPERTROPHY AND NOVEL MEDICAMENT COMBINATIONS  
The present invention relates to the new use of bradycardiac substances such as a Ca++ channel blocker, beta-receptor blocker or if channel blocker, the if channel blockers being preferred,...
US20090123387 BUCCAL, POLAR AND NON-POLAR SPRAY OR CAPSULE CONTAINING CARDIOVASCULAR OR RENEAL DRUGS  
Buccal aerosol sprays or capsules using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in...
US20070078080 N4-Acylcytosine Nucleosides for Treatment of Viral Infections  
The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections,...
US20120101052 15-THIA STEROID COMPOUNDS AND COMPOSITIONS  
The invention relates to the use of compounds to treat a number of conditions, such as thrombocytopenia, neutropenia or the delayed effects of radiation therapy. Compounds that can be used in the...
US20070123448 Novel chemical entities affecting neuroblastoma tumor-initiating cells  
Disclosed are neuroblastoma tumor-initiating cell inhibiting compositions comprising chemical entities capable of affecting neuroblastoma tumor-initiating cells. Pharmaceutical preparations that...
US20060166903 Phosphocholine linked prodrug derivatives  
Disclosed are compounds of general formula (I) that function as prodrugs, thereby increasing bioavailabilities of the linked therapeutic agents, wherein the LINKER is (i) substituted or...
US20060135443 Use of Na*/K*-ATPase inhibitors and antagonists thereof  
The reagent, pharmaceutical formulation, kit, and methods of the invention provides a new approach for treating hypoxia-related pathological conditions, such as Alzheimer's Disease, and those...
US20050026849 Water soluble formulations of digitalis glycosides for treating cell-proliferative and other diseases  
The present invention provides method, preparation and use of a variety of pharmaceutical composition containing at least one digitalis glycosides such as oleandrin, odoroside-A, neriifolin,...
US20140256660 ANTIBIOTIC CONJUGATES LINKED WITH STEROID DRUGS  
The present invention describes novel single drug entities, formed by the linkage of an antibiotic with a steroidal drug via a linker. Upon topical application to the eye, the conjugate would...
US20080112955 METHOD AND COMPOSITION FOR PREVENTING PAIN IN SICKLE CELL PATIENTS  
A method of preventing pain in a sickle cell patient is disclosed. The method includes orally administering to the patient, an amount of an active agent effective on oral administration to inhibit...
US20070060541 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections  
2′ and 3′-Prodrugs of 1′, 2′, 3′ or 4′-branched β-D or β-L nucleosides, or their pharmaceutically acceptable salts and derivatives are described, which are useful in the prevention and treatment...
US20070060505 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections  
2′ and 3′-Prodrugs of 1′, 2′, 3′ or 4′-branched β-D or β-L nucleosides, or their pharmaceutically acceptable salts and derivatives are described, which are useful in the prevention and treatment...
US20070060503 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections  
2′ and 3′-Prodrugs of 1′, 2′, 3′ or 4′-branched β-D or β-L nucleosides, or their pharmaceutically acceptable salts and derivatives are described, which are useful in the prevention and treatment...
US20060111306 DEHYDROEPHIANDROSTERONE AND UBIQUINONE COMPOSITIONS FOR TREATING ASTHMA AND BRONOCONSTRICTION  
A composition and various formulations comprise preventative or therapeutic amounts of an epiandrosterone, analogue thereof or salt thereof, and/or a ubiquinone or salt thereof, and a...
US20050250709 Anti-neoplastic agents, combination therapies and related methods  
In certain aspects, the invention relates to the discovery of novel compositions for use in the treatment of a neoplastic disorder. Further aspects of the invention relate to the discovery that...
US20070060504 2' and 3'-nucleoside prodrugs for treating Flaviviridae infections  
2′ and 3′-Prodrugs of 1′, 2′, 3′ or 4′-branched β-D or β-L nucleosides, or their pharmaceutically acceptable salts and derivatives are described, which are useful in the prevention and treatment...
US20050239867 Methods of using and compositions comprising PDE4 modulators for the treatment and management of pulmonary hypertension  
Methods of treating, preventing and managing pulmonary hypertension are disclosed. Specific methods encompass the administration of a PDE4 modulator, or a pharmaceutically acceptable salt, solvate...
US20070167384 Modified polynucleotides for use in rna interference  
Methods and compositions for performing RNA interference comprising a wide variety of stabilized siRNAs suitable for use in serum-containing media and for in vivo applications, such as therapeutic...
US20060205679 Topical and oral formulations of cardiac glycosides for treating skin diseases  
The present invention provides method, preparation and use of a variety of pharmaceutical compositions containing at least one digitalis glycoside such as oleandrin, odoroside-A, neriifolin,...
US20050239842 Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of pulmonary hypertension  
Methods of treating, preventing and managing pulmonary hypertension are disclosed. Specific methods encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable...
US20110160154 SUBSTITUTED PIPERAZINES  
Disclosed herein are substituted piperazine late Na+ channel modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
US20050059615 Transmucosal dosage forms for brain-targeted steroid chemical delivery systems  
Provided are pharmaceutical compositions of an essentially saturated complex of a steroidal chemical delivery system with cyclodextrin, formulated into a transmucosal dosage form, and methods for...
US20150313926 SYN3 COMPOSITIONS AND METHODS  
Disclosed are aqueous and nonaqueous solution formulations containing agents that are useful for treating cancer.
US20050004045 Substances for use in treating psoriasis  
It is disclosed the use of diacerein or a pharmaceutically acceptable derivative thereof for the manufacture of a pharmaceutical composition for the treatment of psoriasis or diseases associated...
US20160067270 USE OF GINSENOSIDE F2 FOR PROPHYLAXIS AND TREATMENT OF LIVER DISEASE  
Provided are use of ginsenoside F2 in the prevention, improvement or treatment of liver disease, and a pharmaceutical composition, a health functional food, and a feed composition including...
US20070212329 Vaccine Compositions Comprising An Interleukin 18 And Saponin Adjuvant System  
This invention relates to a combination therapy that finds utility in the treatment or prophylaxis of infectious diseases, cancers, autoimmune diseases and related conditions. In particular, the...
US20120156146 Compositions and Methods for Improving the Appearance of Facial Texture  
A method of improving the appearance of facial texture may comprise the step of applying a composition comprising an effective amount of a material that regulates hyaluronic acid synthesis to an...
US20110236510 PREGNANE GLYCOSIDE COMPOSITIONS AND CARALLUMA EXTRACT PRODUCTS AND USES THEREOF  
Pregnane glycoside or a Caralluma extract including the pregnane glycoside of the present invention can be used for medical purposes and as food additives, such as a treatment of obesity, a...
US20110136750 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS  
As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating...
US20110136749 COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS  
As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating...
US20060240129 Skin tissue regeneration promoters comprising ginsenoside Rb1  
The present invention provides efficacious preparations for intravenous administration, preparations for external or topical application to skin, preparations for external or topical application...
US20060116331 Glycosylceramide analogues  
Glycosylceramide analogues are disclosed in which the ceramide moiety and optionally the carbohydrate moiety are modified or replaced. These analogues are useful as immunomodulators, antitumor...
US20100048496 Core 2 GlcNAc-T inhibitors  
A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective...
US20070196396 Controlled release pharmaceutical compositions with improved bioavailability  
The present invention provides a controlled release oral pharmaceutical composition having a therapeutically effective amount of one or more pharmacologically active agent having low...
US20070104805 Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives  
The present invention is directed to compositions containing a pine nut oil and an extract from the genus Hoodia or Trichocaulon and methods of treatment for weight loss.
US20060019907 Guggulsterone: an inhibitor of nuclear factor - kappaB and IkappaBalpha kinase activation and uses thereof  
The present invention provides an inhibitor of NF-κB, guggulsterone and its analogs. Guggulsterone suppresses NF-κB activation induced by TNF, phorbol ester, okadaic acid, cigarette smoke, H2O2...
US20050209169 Use of boswellic acid and its derivatives for inhibiting normal and increased leucocytic elastase or plasmin activity  
The invention concerns the use of pure boswellic acid, a physiologically acceptable salt, a derivative, a salt of the derivative or a plant preparation containing boswellic acid for preventing...
US20050113316 Process for producing dammarane sapogenins and ginsenosides  
This invention relates to a process for producing sapogenins and ginsenosides comprising the steps of mixing a ginsenoside extract with water, mixing the ginsenoside extract and water with an...
US20060233876 Compositions and methods for reducing cardiovascular morbidity and/or mortality  
The present invention is related to a method for reducing cardiovascular morbidity and/or mortality comprising administering a combination comprising an ACE inhibitor and a CCB, specifically...
US20050282732 Pharmaceutical compositions and treatment methods-7  
The invention provides compositions comprising formula 1 steroids, e.g., 16α-bromo-3β-hydroxy-5α-androstan-17-one hemihydrate and one or more excipients, typically wherein the composition...
US20120058962 BUCCAL AND/OR SUBLINGUAL THERAPEUTIC FORMULATION  
A buccal and/or sublingual formulation comprising one or more active compounds; and a buccal matrix which releases the active compounds at a predetermined rate for transport across the buccal...
US20100048495 Core 2 GlcNAc-T inhibitors III  
A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective...

Matches 1 - 50 out of 333 1 2 3 4 5 6 7 >