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US20150080410 Cancer Specific Mitotic Network  
Developed here is a mitotic network comprising a signature of up to 54 genes, and including also sub-sets of genes within the signature, which can identify members by requiring higher correlation...
US20150111898 Method for the treatment of premenstrual and other female sexual disorders  
The invention relates to a method for the treatment of premenstrual and other female sexual disorders comprising the administration of a therpeutically effective amount of flibanserin.
US20130079356 Method for the treatment of premenstrual and other female sexual disorders  
The invention relates to a method for the treatment of premenstrual and other female sexual disorders comprising the administration of a therpeutically effective amount of flibanserin.
US20110178079 GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS  
Novel guanidine compounds having the formula in which R1, R2, and R4 are as defined, are effective as sodium channel dockers in neuronal mammalian cells and as anesthetics and/or analgesics,...
US20120039913 Selective Histamine H4 Receptor Antagonists for the Treatment of Vestibular Disorders  
The invention relates to Histamine H4 receptor antagonists or inhibitors of Histamine H4 receptor gene expression for the treatment and/or the prevention of vestibular disorders.
US20150224058 FORMULATIONS OF FLIBANSERIN  
The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin.
US20130209519 FORMULATIONS OF FLIBANSERIN  
The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin.
US20110045090 FORMULATIONS OF FLIBANSERIN  
The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin.
US20150250783 Treatment of Vasomotor Symptoms  
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therapeutically effective amount of flibanserin.
US20140005203 Treatment of Vasomotor Symptoms  
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therpeutically effective amount of flibanserin.
US20110136825 Treatment of Vasomotor Symptoms  
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therapeutically effective amount of flibanserin.
US20110033461 Combination Therapy for the Treatment of Cancer  
Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed.
US20150072994 Use of Flibanserin in the Treatment of Obesity  
The invention relates to a method for the treatment of obesity and related diseases comprising the administration of a therapeutically effective amount of Flibanserin.
US20140037647 MOLECULAR SUBTYPING, PROGNOSIS AND TREATMENT OF PROSTATE CANCER  
Disclosed herein are new prognostic molecular markers for prostate cancer. More specifically, the invention has identified that overexpression or amplification of at least one of AURKA or MYCN...
US20130210771 METHODS AND COMPOSITIONS FOR TREATING CANCERS  
This invention provides a combination of antagonists of the hedgehog signaling pathway with a BCR-ABL inhibitor. The combination of the present invention may be used for treating cancers known to...
US20110206780 MORPHINAN MODULATORS OF NMDA RECEPTORS, SIGMA1 RECEPTORS, SIGMA2 RECEPTORS, AND/OR A3B4 NICOTINIC RECEPTORS  
The present invention relates to new morphinan modulators of NMDA receptors, σ1 receptors, σ2 receptors, and/or α3β4 nicotinic receptors, pharmaceutical compositions thereof, and methods of use...
US20130203671 Flibanserin for the Treatment of Urinary Incontinence and Related Diseases  
The invention relates to the use of Flibanserin for the treatment or prevention of urinary incontinence and related diseases. In a further embodiment, the instant invention is directed to...
US20130157997 BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS  
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B′, X, Y, R1, R1′, R2, R2′, R3, R3′, R5, R5′, R6, m, n, or p are as defined herein, are...
US20140121195 SUBSTITUTED BENZIMIDAZOLES AND BENZOPYRAZOLES AS CCR(4) ANTAGONISTS  
Benzimidazole, benzopyrazole and benzotriazole compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft...
US20130165423 SUBSTITUTED BENZIMIDAZOLES AND BENZOPYRAZOLES AS CCR(4) ANTAGONISTS  
Benzimidazole, benzopyrazole and benzotriazole compounds are provided which bind to CCR(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft...
US20130197010 Use of Flibanserin for the Treatment of Sexual Disorders in Females  
The invention is directed to the use of flibanserin or a pharmacologically acceptable derivative thereof, for the preparation of a medical composition for the treatment of Sexual Disorder in...
US20150238484 Use of Flibanserin for the Treatment of Sexual Disorders in Females  
The invention is directed to the use of flibansenn or a pharmacologically acceptable derivative thereof, for the preparation of a medical composition For lbe treatment of Sexual Disorder in...
US20100022558 TREATMENT OF INSOMNIA  
The invention relates to the use of Flibanserin for the preparation of medicaments useful for the treatment of Insomnia.
US20140336200 ARYLOSULFONAMIDES FOR THE TREATMENT OF CNS DISEASES  
Arylsulphonamide derivatives of formula (I) and pharmaceutically acceptable salts thereof. The compounds may be useful for the treatment and/or prevention of disorders of the central nervous system.
US20130172365 ARYLOSULFONAMIDES FOR THE TREATMENT OF CNS DISEASES  
Arylsulphonamide derivatives of formula (I) and pharmaceutically acceptable salts thereof. The compounds may be useful for the treatment and/or prevention of disorders of the central nervous system.
US20150202195 SMALL MOLECULE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DENGUE VIRUS INFECTION  
Methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods of using the compounds and...
US20140194402 PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY  
Described herein are methods for using compounds that activate pyruvate kinase.
US20110158940 SAMLL MOLECULE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DENGUE VIRUS INFECTION  
Methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods of using the compounds and...
US20150231126 COMBINATIONS OF 5-HT2A INVERSE AGONISTS AND ANTAGONISTS WITH ANTIPSYCHOTICS  
Combinations of 5-HT2A inverse agonists or antagonists such as pimavanserin with antipsychotics such as risperidone are shown induce a rapid onset of antipsychotic action and increase the...
US20110059905 METHODS OF TREATING DISEASE-INDUCED ATAXIA AND NON-ATAXIC IMBALANCE  
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.
US20110245179 Composition for Prevention or Treatment of Heart Failure  
Provided are a composition for preventing or treating heart failure and a method for screening an agent for treating heart failure. The present disclosure demonstrates for the first time that...
US20150166543 PHENYL-UREA AND PHENYL-CARBAMATE DERIVATIVES AS INHIBITORS OF PROTEIN AGGREGATION  
The present invention relates to certain phenyl-urea and phenyl-carbamate derivatives, pharmaceutical compositions containing them, and methods of using them, including methods for preventing,...
US20070254885 Use of type V phosphodiesterase inhibitors in the treatment of exercise induced pulmonary hemorrhage in the equine  
The use of type V phosphodiesterase inhibitors as a novel independent therapeutic modality in the treatment of exercise induced pulmonary hemorrhage in equine is described. The type V...
US20130172342 BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT  
The present invention is directed to methods of treating diseases or conditions mediated by elevated persistent sodium channel, such as ocular disorders, pain, multiple sclerosis, and seizure...
US20110230481 DERIVATIVES OF TETRABROMOBENZIMIDAZOLE, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, A METHOD OF USING THE SAME, A METHOD FOR MODULATING OR REGULATING SERINE/THREONINE KINASES, AND SERINE/THREONINE KINASES MODULATING AGENT  
A derivative of tetrabromobenzimidazole, a process for the preparation thereof, a pharmaceutical composition, a method for using the same, a method for modulating or regulating serine/threonine...
US20120184535 COMPOUND, A PROCESS FOR ITS PREPARATION, A PHARMACEUTICAL COMPOSITION, USE OF A COMPOUND, A METHOD FOR MODULATING OR REGULATING SERINE/THREONINE KINASES AND A SERINE/THREONINE KINASES MODULATING AGENT  
A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine and tyrosine kinases and a serine/threonine and...
US20080096872 Composition for Treatment of Pain Specification  
A method for the treatment of pain and/or inflammation in a subject by the administration of N-acetyl-cysteine (NAC) or derivative thereof and a pain and/or anti-inflammatory medication. The pain...
US20060235005 Use of phosphodiesterase 5 (PDE5) inhibitors in the treatment of schizophrenia  
The use of phosphodiesterase 5 (PDE5) inhibitors for treatment of schizophrenia is described. Suitable PDE5 inhibitors for use for treatment of schizophrenia include sildenafil, vardenafil,...
US20110071145 Raf Modulators And Methods Of Use  
The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate...
US20150104439 PHARMACEUTICAL REMOVAL OF NEURONAL EXTENSIONS FROM A DEGENERATING DISC  
The invention provides a method for alleviating discogenic pain by administering a therapeutic agent that disrupts neuronal and/or vascular elements in the disc, which is typically a degenerated...
US20140378917 TRANSDERMAL THERAPEUTIC SYSTEM WITH A LOW TENDENCY TO SPONTANEOUSLY CRYSTALLIZE  
The present invention provides transdermal therapeutic systems for dispensing a pharmaceutical product, in particular a pharmaceutical product with a low tendency to spontaneously crystallize. The...
US20080242678 Use of Flibanserin in the Treatment of Obesity  
The invention relates to a method for the treatment of obesity and related diseases comprising the administration of a therapeutically effective amount of Flibanserin.
US20110112091 DERIVATIVES OF TETRABROMOBENZIMIDAZOLE, A PROCESS FOR THE PREPARATION THEREOF, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, A METHOF OF USING THE SAME, A METHOD FOR MODULATING OR REGULATING SERINE/THREONINE KINASES, AND SERINE/THREONINE KINASES MODULATING AGENT  
A derivative of tetrabromobenzimidazole, a process for the preparation thereof, a pharmaceutical composition, a method for using the same, a method for modulating or regulating serine/threonine...
US20150051221 Use of Flibanserin for the Treatment of Post-Menopausal Sexual Desire Disorders  
The invention relates to the use of flibanserin for the preparation of a medicament for the treatment of post-menopausal Sexual Desire Disorders.
US20130190326 Use of flibanserin for the treatment of post-menopausal sexual desire disorders  
The invention relates to the use of flibanserin for the preparation of a medicament for the treatment of post-menopausal Sexual Desire Disorders.
US20140371202 INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME  
The present teaching provide indazole compounds represented by Structural Formulae (I) or (I′) or a pharmaceutically acceptable salt thereof. Also described are pharmaceutical compositions and...
US20140213592 Protein Kinase Inhibitors (Variants), Use Thereof in Treating Oncological Diseases and a Pharmaceutical Composition Based Thereon  
The present invention relates to the treatment of oncological, chronic inflammatory and similar diseases with the aid of new families of chemical compounds having improved efficiency with regard...
US20090053329 COMBINATIONS OF 5-HT2A INVERSE AGONISTS AND ANTAGONISTS WITH ANTIPSYCHOTICS  
Combinations of 5-HT2A inverse agonists or antagonists such as pimavanserin with antipsychotics such as risperidone are shown to induce a rapid onset of antipsychotic action and increase the...
US20090312242 FLIBANSERIN FOR THE TREATMENT OF URINARY INCONTINENCE AND RELATED DISEASES  
The invention relates to the use of Flibanserin for the treatment or prevention of urinary incontinence and related diseases. In a further embodiment, the instant invention is directed to...
US20120070410 IMIDAZOLOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF  
Compounds, compositions and methods are provided for modulating the activity of receptor kinases and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder...
Matches 1 - 50 out of 419 1 2 3 4 5 6 7 8 9 >