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Document Title |
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US20120087952 |
Pulmonary Delivery in Treating Disorders of the Central Nervous System
A method for treating a disorder of the central nervous system includes administering to the respiratory tract of a patient a drug which is delivered to the pulmonary system, for instance to the... |
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US20130059829 |
TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention... |
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US20140072623 |
GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. |
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US20130224289 |
GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. |
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US20120282307 |
GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. |
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US20120064129 |
GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. |
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US20120064181 |
P2X3 Receptor Antagonists for Treatment of Pain
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or... |
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US20110206783 |
P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or... |
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US20110237563 |
FAST DISSOLVING DRUG DELIVERY SYSTEMS
The present invention related to the administration of bioactive agents via oral fast dispersing/dissolving drug delivery systems for treating illnesses of patient with critical buccal condition,... |
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US20130131028 |
METHODS FOR TREATMENT OF SLEEP-RELATED BREATHING DISORDERS
Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditions. |
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US20130005650 |
Methods and compositions for treating diseases associated with pathogenic proteins
Methods and compositions are provided comprising acriflavine for inhibiting and treating diseases and disorders associated with pathogenic proteins causing neurodegenerative diseases and amyloid... |
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US20140005135 |
STABLE FORMULATIONS FOR PARENTERAL INJECTION OF SMALL MOLECULE DRUGS
Disclosed is a stable liquid formulation for parenteral injection comprising a biocompatible non-aqueous solvent and a small molecule drug, or a salt thereof, solubilized within the non-aqueous... |
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US20150141410 |
GPR17 Receptor Modulators
Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis,... |
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US20120128735 |
METHODS OF TREATMENT USING A GASTRIC RETAINED GABAPENTIN DOSAGE
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. |
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US20120064168 |
METHODS OF TREATMENT USING A GASTRIC RETAINED GABEPENTIN DOSAGE
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. |
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US20120270783 |
Rapid opioid detoxification
Rapid opioid detoxification procedures are provided which include sedating a patient with an anesthetic agent having a short full recovery period. The patient is administered an opioid antagonist... |
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US20150118302 |
Immediate Release Abuse-Deterrent Granulated Dosage Forms
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse by ingestion of multiple individual... |
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US20140234443 |
5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF
Novel 5-HT3 receptor modulators are disclosed. These compounds are used in the treatment of various disorders, including chemotherapy-induced nausea and vomiting, post-operative nausea and... |
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US20120219641 |
5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF
Novel 5-HT3 receptor modulators are disclosed. These compounds are used in the treatment of various disorders, including chemotherapy-induced nausea and vomiting, post-operative nausea and... |
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US20110059159 |
NANOSCALE BOUND BILAYERS, METHODS OF USE AND PRODUCTION
Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly... |
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US20150099742 |
PHANTOM PHENOMENA TREATMENT
The present invention relates to a substance for the treatment of the phantom phenomena of tinnitus and/or phantom pain, a method for the diagnosis and for the treatment of these phantom phenomena. |
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US20150056308 |
INTRANASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to... |
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US20150005260 |
METHODS FOR THE DETECTION AND THE TREATMENT OF DIASTOLIC DYSFUNCTION
The present invention relates to methods and kits for detecting diastolic dysfunction in subjects without clinical signs of heart failure. |
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US20150157558 |
METHODS OF TREATMENT USING A GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. |
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US20130302417 |
METHODS OF TREATMENT USING A GASTRIC RETAINED GABAPENTIN DOSAGE FORM
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. |
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US20130079336 |
Treatment of Prolonged Status Epilepticus
Methods for terminating, preventing, and/or treating status epilepticus are generally provided. The method can include administering a prophylactically or therapeutically effective amount of... |
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US20150247847 |
DIAGNOSTIC METHOD FOR DETECTING AN AUTOIMMUNE DISEASE AND RELATED SUBJECT-MATTER
The present invention relates to a polypeptide or protein for use in a method of diagnosis or treatment of an autoimmune disease in a subject, characterized in that said polypeptide or protein... |
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US20120040961 |
PYRIMIDO-DIAZEPINONE KINASE SCAFFOLD COMPOUNDS AND METHODS OF TREATING DISORDERS
The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, AbI,... |
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US20150030683 |
FORMULATIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF PRE-MCI AND/OR PRE-ALZHEIMER'S CONDITIONS
In certain embodiments the methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's... |
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US20130158017 |
METHODS FOR TREATING OR PREVENTING CANCER AND NEURODEGENERATIVE DISEASES
Provided are methods of treating or preventing a neurodegenerative disease comprising administering to a subject having a neurodegenerative disease an effective amount of a compound of Formula I:... |
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US20140302141 |
Triple Combination Release Multi-layered Tablet
This invention pertains to a multi-layered tablet for a triple combination release of active agents to an environment of use. More particularly, the invention pertains to a multi-layered tablet... |
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US20120208801 |
Aminodiazepines as Toll-Like Receptor Modulators
Provided are compositions and methods useful for modulation signaling through the Toll-like receptor TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation... |
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US20130149282 |
FOOD-BASED UTENSILS AND STORAGE CONTAINERS AND METHODS OF MAKING THE SAME
The disclosure relates to edible and biodegradable eating utensils and edible and biodegradable containers. In one aspect a method of making and preserving an edible and biodegradable utensil or... |
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US20140057903 |
METHODS FOR CHARACTERIZING AND TREATING COGNITIVE IMPAIRMENT IN AGING AND DISEASE
This invention provides methods for identifying genes associated with cognitive impairment and for identifying compounds useful in the treatment of cognitive impairment. The methods can in... |
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US20130045966 |
Method of Lowering Serum Uric Acid Levels With (S)-Tofisopam
Enantiomerically-pure (S)-tofisopam is administered to lower serum uric acid levels in a mammal. |
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US20070065463 |
Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
The invention is directed to topical formulations and methods of treating a migraines and/or cluster headaches, muscle sprains, muscle spasms, spasticity, tension headaches, tension related... |
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US20120101088 |
Transmembrane Penetration Enhancer
A transmembrane penetration enhancer includes a thermotropic liquid crystal suitably prepared for use in a therapeutic system to improve delivery of at least one active ingredient across a... |
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US20140148445 |
Methods of Detecting Amyotrophic Lateral Sclerosis (ALS)
In one aspect, the invention is directed to a method of identifying an individual that has amyotrophic lateral sclerosis (ALS) or is at risk of developing ALS comprising detecting one or more... |
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US20120178797 |
NOVEL THERAPEUTIC AND DIAGNOSTIC PRODUCTS AND METHODS
The present invention relates to the use of p11 as a drug target as well as a tool for the diagnosis, treatment and development of p11/5-HT receptor related disorders. The invention further... |
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US20110274740 |
METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES
The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering... |
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US20120270860 |
METHODS FOR TREATING OR PREVENTING ALCOHOL-RELATED DISORDERS OR CRAVING-RELATED DISORDERS
The invention provides methods for treating or preventing alcohol-related disorders or craving-related disorders comprising administering an effective amount of N-acetylcysteine or a... |
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US20140004082 |
METHODS FOR TREATING LEUKEMIA AND DISORDERS MEDIATED BY CBFBETA AND RUNX1 PROTEINS
A method for treating core binding factor (CBF) leukemia in a subject, comprising administering to a subject having CBF leukemia a therapeutically effective amount of a compound, or a... |
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US20120071468 |
METHODS OF TREATING MILD COGNITIVE IMPAIRMENT (MCI) AND RELATED DISORDERS
The invention provides compositions and methods for the treatment of mild cognitive impairment (MCI), and for inhibiting, reducing, delaying and/or preventing the progression of MCI to Alzheimer's... |
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US20100317619 |
Selective Agents for Pain Suppression
In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of the often chronic, severe and... |
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US20140079666 |
PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA
In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This... |
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US20130281442 |
Compounds for Treatment of Bovine Mastitis
Described herein are methods of treating mastitis in female mammals, e.g., cows, wherein the methods may include administering to mammals in need thereof compounds disclosed herein. |
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US20110230473 |
Methods and Compositions for Treating Status Epilepticus and Seizures Causing Status Epilepticus
Disclosed herein are methods, kits and compositions for treating, preventing, inhibiting, or reducing a seizure, status epilepticus, neuropathogenesis or a neuropathology caused by overstimulation... |
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US20120010198 |
Methods for Treating Sleep Disorders by Cholecystokinin (CCK) Receptor B Antagonists
The present invention relates to a method for preventing or ameliorating a sleep-related breathing disorder. The method involves the use of one or a combination of cholecystokinin (CCK) receptor... |
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US20140011772 |
COMPOSITIONS AND METHODS FOR TREATING CONDITIONS ASSOCIATED WITH NEURONAL DYSFUNCTION
The present invention relates to compositions and methods for the treating and empirically investigating conditions associated with neuronal dysfunction (e.g., chronic pain, epileptic neuronal... |
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US20140072536 |
METHODS OF TREATING MUSCULAR DYSTROPHY
Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In... |