Matches 1 - 50 out of 337 1 2 3 4 5 6 7 >


Match Document Document Title
US20120321612 SYSTEMS AND METHODS FOR TREATING POST-OPERATIVE, ACUTE, AND CHRONIC PAIN USING AN INTRA-MUSCULAR CATHETER ADMINISTRATED COMBINATION OF A LOCAL ANESTHETIC AND A NEUROTOXIN PROTEIN  
Systems, and methods for the use of such systems, are described that allow for the administration of a combination of a sustained release local anesthetic compound (such as bupivicaine) through a...
US20120053126 Injection Paradigm for Administration of Botulinum Toxins  
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional...
US20120178695 METHODS OF TREATING NEUROPATHIC PAIN  
The disclosure relates, at least in part, to methods of treating neuropathic pain in a patient in need thereof by administering an effective amount of a disclosed compound, e.g. a peptide NMDA...
US20150231068 Treatment of Migraine Headaches with Presynaptic Neurotoxin  
The present invention provides a method for treating a patient for migraine headache, including symptoms associated with migraine headache, such as migraine associated vertigo, which comprises...
US20130236444 TREATMENT OF MIGRAINE HEADACHE WITH DIFFUSION OF TOXIN IN NON-MUSCLE RELATED FORAMINAL SITES  
A method for treating a patient with migraine headache includes administering to the patient a therapeutically effective amount of an invertebrate presynaptic neurotoxin in a pharmaceutically safe...
US20140051638 TARGETED DELIVERY OF BOTULINUM TOXIN TO THE SPHENOPALATINE GANGLION  
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are...
US20120053127 TARGETED DELIVERY OF BOTULINUM TOXIN TO THE SPHENOPALATINE GANGLION  
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are...
US20120083453 TREATMENT USING NEUBLASTIN POLYPEPTIDES  
The invention relates to treatments of neuropathic pain, including tactile allodynia, and to treatments for reducing loss of pain sensitivity associated with neuropathy. The present treatments...
US20110118189 NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE  
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,...
US20130303459 TREATMENT OF ALLODYNIA, HYPERALGESIA, SPONTANEOUS PAIN AND PHANTOM PAIN  
The present invention relates to the use of Meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain. In a preferred embodiment the disorder to be treated is...
US20120108518 TREATMENT OF ALLODYNIA, HYPERALGESIA, SPONTANEOUS PAIN AND PHANTOM PAIN  
The present invention relates to the use of Meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain. In a preferred embodiment the disorder to be treated is...
US20120148583 CYTOKINE ANTAGONISTS FOR NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS  
A method for delivering a biologic pharmaceutical, comprising: administering an effective amount of a biologic pharmaceutical to a patient in need thereof by perispinal injection, without direct...
US20110070237 METHODS OF MODULATING AND IDENTIFYING AGENTS THAT MODULATE INTRACELLULAR CALCIUM  
Methods are provided for identifying agents that modulate intracellular calcium. Also provided are methods of modulating calcium within cells and methods of identifying proteins involved in...
US20110245149 METHODS TO PREVENT AND TREAT DISEASES  
This invention discloses methods and compositions that can treat a variety of tissue injuries and infections. Tissue-derived leukocyte chemotactic factors are rapidly released after injury to...
US20130310324 HUWENTOXIN-IV VARIANTS AND METHODS OF USE  
The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.
US20110129508 METHODS AND COMPOSITIONS FOR THE MANAGEMENT OF PAIN USING OMEGA-CONOTOXINS  
The present invention relates to the management of pain (nociceptive, neuropathic, inflammatory and disease related pains), using omega-conotoxins alone or in combination with neuronal excitation...
US20110105405 METHOD FOR ALLEVIATING PAIN USING PROTEIN ASSOCIATED WITH MYC AND RELATED COMPOUNDS, AND ASSAYS FOR IDENTIFYING SUCH COMPOUNDS  
Use of PAM or functional fragments or derivatives thereof for the preparation of pharmaceutical compounds.
US20110104301 METHODS OF REDUCING PAIN AND INFLAMMATION  
Provided herein are methods of treating or preventing pain and/or inflammation in a subject comprising administering to the subject a transient receptor potential (TRP) ion channel inhibitor.
US20110189161 NUTRIGENOMICS METHODS AND COMPOSITIONS  
The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well...
US20110028402 SUBSTANCE P-SAPORIN (SP-SAP) CONJUGATES AND METHODS OF USE  
This invention provides a conjugate comprising Substance P, or an analog thereof, and a protein, such as Saporin, that inhibits protein synthesis. This invention provides a method of reducing the...
US20060120993 Treatment of lesions of the soft tissues  
The invented remedy allows cleaning up the area from necrotic tissues and facilitating reduced perifocal oedema and infiltration as well as lessening pain syndrome during suppurative inflammation...
US20050070472 Treatment of pancreatitis with amylin  
The disclosed invention provides for the treatment of pancreatitis, and the alleviation of pain associated therewith, with amylin, amylin agonists and amylin analogs.
US20120202744 DUAL ANTAGONISM OF ENDOTHELIN TYPE A AND BRADYKININ B1 RECEPTORS FOR TREATING PAIN AND PREVENTING CARTILAGE DEGRADATION  
The present invention relates to the field of anatomy, and more particularly to the control of pain and to the prevention and treatment of osteoarthritic cartilage degradation. Described herein...
US20130324462 Method of Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides  
The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described.
US20110104181 MODULATION OF SYNAPTOGENESIS  
The present invention describes methods and compositions for modulating synaptogenesis and axon and/or dendritic growth. The methods include the use of agents that modulate a thrombospondin and/or...
US20130108602 METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE  
Methods of decreasing, reducing, inhibiting, suppressing, limiting or controlling an undesirable or aberrant immune response, immune disorder, inflammatory response, or inflammation in a subject;...
US20140179615 Glutathione and Acetaminophen Composition and Preparation Method Thereof  
A pharmaceutical composition of glutathione and acetaminophen and preparation method thereof. The active ingredients of the composition include glutathione with composition ration of 0.1%˜99.9%...
US20120245096 TARGETED DELIVERY OF BOTULINUM TOXIN FOR THE TREATMENT AND PREVENTION OF TRIGEMINAL AUTONOMIC CEPHALGIAS, MIGRAINE AND VASCULAR CONDITIONS  
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are...
US20120040911 TARGETED DELIVERY OF BOTULINUM TOXIN FOR THE TREATMENT AND PREVENTION OF TRIGEMINAL AUTONOMIC CEPHALGIAS, MIGRAINE AND VASCULAR CONDITIONS  
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are...
US20060241053 Compounds and their analgesic applications  
Application of peptides with analgesic properties as the active ingredient in devices for the direct application of medication to the site of their expected analgesic activity, particularly in the...
US20150231203 TREATMENT OF PAIN BY INHIBITION OF USP5 DE-UBIQUITINASE  
The invention provides methods treating pain by inhibiting a Cav3.2 channel expression or function, including the use of contacting said channel in situ with an inhibitor of USP5 or an inhibitor...
US20100297125 METHODS OF TREATING PAIN USING ANTAGONISTS OF IL-31, IL-31RA AND/OR OSMRB  
Use of antagonists to IL-31Ra and OSMRb are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such...
US20130203678 COMPSTATIN ANALOGS FOR TREATMENT OF NEUROPATHIC PAIN  
In some aspects, the present invention provides methods of treating a subject in need of treatment for neuropathic pain, the method comprising administering a compstatin analog to the subject. In...
US20110124562 APOAEQUORIN-CONTAINING COMPOSITIONS AND METHODS OF USING SAME  
Compositions containing apoaequorin and methods for their use in treating symptoms and disorders related to calcium imbalances associated with, for example, sleep quality, energy quality, mood...
US20140193466 SILK COMPOSITIONS AND METHODS OF USING SAME  
The present invention provides for silk-derived compositions for treating a wide variety of ocular conditions. The composition is produced by processing the silk cocoon into a water-based solution...
US20130252902 TYPE A2 BOTULINUM TOXIN PREPARATION  
A method for treating a patient who has a neutralizing antibody to a type A1 botulinum toxin. The method includes administering 150 kDa type A neurotoxin from type A2 Clostridium botulinum (A2...
US20110112035 THERAPEUTIC USE OF A GROWTH FACTOR, METRNL  
The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on the biological function of a secreted therapeutic protein, METRNL,...
US20130324475 Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation  
A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that exhibits...
US20140057845 COMPOSITION FOR TREATING, IMPROVING, OR PREVENTING PAIN  
In order to provide a composition for treating, improving, or preventing pain, it has been found out that a metallothionein protein is expressed in a normal peripheral nerve, and that the...
US20100319073 GDE Compositions and Methods  
The present invention relates to compositions to treat glycerophosphodiester phosphodiesterase (GDE) related disorders. The invention also relates to methods treating GDE related disorders. The...
US20130210740 NEO-TRYPTOPHAN  
Methods of inducing antinociception in a human are described. The method includes the step of administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human...
US20120108519 NEO-TRYPTOPHAN  
Methods of inducing antinociception in a human are described. The method includes the step of administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human...
US20150132275 COMPOSITION FOR PREVENTING HEADACHES  
The present invention concerns a non-toxic solid pharmaceutical composition for oral administration, containing one or more cysteine compounds from the group of L-cysteine, D-cysteine and N-acetyl...
US20120003290 METHOD FOR REDUCING PAIN  
The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in...
US20110021437 METHOD FOR REDUCING PAIN WITH ZICONOTIDE AND BACLOFEN  
The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in...
US20120058950 DETECTION OF NEUROPEPTIDES ASSOCIATED WITH PELVIC PAIN DISORDERS AND USES THEREOF  
Diagnostic assessment and therapeutic treatment of pelvic pain disorders, including bladder disorders, bowel disorders, and/or reproductive tissue or organ disorders that are characterized by...
US20150140046 COMPOUNDS WHICH INHIBIT NEURONAL EXOCYTOSIS  
Compounds of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2 (I) their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts,...
US20140087993 PEPDUCIN DESIGN AND USE  
Disclosed here is the rational design and use of potent and specific GPCR antagonist pepducins based on GPCR regions such as the third intracellular loop and adjacent regions.
US20060269484 Medicament formulations  
Disclosed are medicinal compositions, and devices, methods and systems which use same, comprising a propellant and at lease one medicinally active compound, said propellant comprising at least one...
US20110021436 METHOD FOR REDUCING PAIN WITH ZICONOTIDE AND MORPHINE  
The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in...

Matches 1 - 50 out of 337 1 2 3 4 5 6 7 >