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US20140343027 EDIBLE OILS TO ENHANCE DELIVERY OF ORALLY ADMINISTERED STEROIDS  
The present invention relates to the formulation of steroids, including neurosteroids (e.g., allopregnanolone (ALP)) in edible oils to enhance their absorption when administered, e.g., orally or...
US20150079116 DIAGNOSTIC TOOLS FOR RESPONSE TO 6-THIOPURINE THERAPY  
NK cell licensing predisposes patients to chronic inflammatory disease. Methods and kits to diagnose and treat chronic inflammatory disease based on genetic haplotype and cytokine profile are...
US20110250153 OLIGOMERIC BIOSURFACTANTS IN DERMATOCOSMETIC COMPOSITIONS  
Oligomeric acylated biosurfactants (“OABs”) having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal...
US20120321673 TRANSDERMAL DRUG DELIVERY SYSTEM AND METHOD OF USING THE SAME  
A transdermal drug delivery system comprising a steroid as an active agent, wherein the steroid may be clobetasol propionate, betamethasone dipropionate, amcinonide, or loteprednol etabonate. The...
US20110263553 STEROID ANALOGUES FOR NEUROPROTECTION  
Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are...
US20120201857 Transdermal delivery system for therapeutics  
The present invention provides a method and product for transdermal delivery of therapeutics, including neurotoxins and methods for use thereof. The method and system comprises pharmaceutical...
US20140011793 NEW STEROIDS HAVING INCREASED WATER SOLUBILITY AND RESISTANCE AGAINST METABOLISM, AND METHODS FOR THEIR PRODUCTION  
Steroid compounds having increased resistance against metabolism and increased water solubility are disclosed, together with methods for their production. These substances are suitable for the...
US20140011779 NEW STEROIDS HAVING INCREASED WATER SOLUBILITY AND RESISTANCE AGAINST METABOLISM, AND METHODS FOR THEIR PRODUCTION  
Steroid compounds having increased resistance against metabolism and increased water solubility are disclosed, together with methods for their production. These substances are suitable for the...
US20110190243 DIAGNOSIS AND TREATMENT OF BACK PAIN  
The present invention relates to methods of diagnosing and/or treating lower back pain (LBP). In one embodiment, the invention relates to a system for diagnosis of a form of lower back pain in an...
US20110123517 DISSOLVABLE PHARMACEUTICAL IMPLANT  
A pharmaceutical implant may include a pharmaceutical and at least one excipient, and may be configured to be implanted in a body of a patient. The at least one excipient may dissolve after...
US20130225540 SUPPRESSION OF GLIAL FIBRILLARY ACIDIC PROTEIN  
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell....
US20130273136 SUSTAINED DRUG DELIVERY SYSTEM  
A drug delivery system for delivering a drug at a sustained constant rate for a long period, which can be transplanted into an affected part safely and in a simple manner and can deliver a drug to...
US20110038832 METHOD FOR TREATMENT OF MACULAR DEGENERATION USING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE  
Provided herein are methods of treating macular degeneration, which comprises administering to a patient in need thereof a therapeutically effective amount of...
US20130142781 PEG BASED HYDROGEL FOR PERIPHERAL NERVE INJURY APPLICATIONS AND COMPOSITIONS AND METHOD OF USE OF SYNTHETIC HYDROGEL SEALANTS  
Hydrogels that may be used for treating peripheral nerves and related methods are provided. Synthetic hydrogel sealants, methods of forming synthetic hydrogel sealants, and the use of synthetic...
US20110311442 DIRECT CELLULAR ENERGY DELIVERY SYSTEM  
A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group...
US20100330086 CATIONIC STEROID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE  
The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a...
US20110002918 METHODS OF TREATING DISEASED TISSUE  
Treatment protocols for severe psoriasis include administering biologics, stopping all administration of the biologics after the severity of the psoriasis has reduced and has reached an...
US20110286998 METHODS FOR TREATING AND PREVENTING CANCERS THAT EXPRESS THE HYPOTHALAMIC-PITUITARY-GONADAL AXIS OF HORMONES AND RECEPTORS  
Methods are provided for treating HPG axis-positive cancers, preventing or slowing proliferation of cells of HPG axis-positive cancer origin, preventing HPG axis-positive cancers in a patient at...
US20150038552 ESOPHAGEAL MICRORNA EXPRESSION PROFILES IN EOSINOPHILIC ESOPHAGITIS  
Methods and compositions disclosed herein generally relate to methods of treating eosinophilic esophagitis (EE) and eosinophilic disorders by providing or enhancing a diagnosis of EE and...
US20110118189 NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE  
Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting,...
US20110123448 OIL BODY CARRIERS, USES IN TARGET THERAPY AND/OR DETECTION OF THE SAME, AND FUSION PROTEINS COMPRISED THEREIN  
An oil body carrier, its uses in target therapy and/or detection, and a fusion protein comprised therein are provided. The oil body carrier comprises: a) the fusion protein, comprising an oil body...
US20110044911 Use of Functionalized Magnetic Nanoparticles in Cancer Detection and Treatment  
The present invention provides methods of detecting a cancer cell in an individual, methods of grading a cancer, and methods of treating a cancer. The methods involve use of functionalized...
US20130190277 Paraffin Wax Embedded Drug Delivery System  
A paraffin wax embedded drug delivery system is a method for combining topical medications with paraffin wax for enhanced delivery and absorption of the topical medication at a treatment area on a...
US20150045334 DIAGNOSTIC METHODS OF EOSINOPHILIC ESOPHAGITIS  
Embodiments of the invention are directed to methods of diagnosing eosinophilic esophagitis (EoE), or remission therefrom in a subject, wherein the methods include applying a sample from the...
US20120114734 NANOSTRUCTURE SURFACE COATED MEDICAL IMPLANTS AND METHODS OF USING THE SAME  
Compositions including a surface or film comprising nanofibers, nanotubes or microwells comprising a bioactive agent for elution to the surrounding tissue upon placement of the composition in a...
US20140213474 GLUCOCORTICOID RECEPTOR ALLELES AND USES THEREOF  
Provided here in are, inter alia, methods of determining whether a patient is resistant or sensitive to glucocorticoid therapy.
US20110059159 NANOSCALE BOUND BILAYERS, METHODS OF USE AND PRODUCTION  
Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly...
US20130149318 PAINTING THE PIA, ARACHNOID, AND SPINAL CORD PARENCHYMA  
A PEG based hydrogel and a procedure for its topical application to the surface of the pia mater of the spinal cord that can be used for intrathecal delivery of diverse drug and biomolecular...
US20070243260 Treatment of Childhood Asthma  
Glycopyrrolate or an analogue thereof is useful for the treatment of childhood asthma.
US20080175905 ESTROGEN/SERM AND ESTROGEN/PROGESTIN BI-LAYER TABLETS  
The present invention is directed to bi-layer tablets comprising at least one estrogen in a first layer and a therapeutic agent in a second layer, and processes for their preparation.
US20140221325 GLOMERULONEPHRITIS BIOMARKERS  
The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment...
US20120035146 IMPLANTS AND METHODS FOR TREATING INFLAMMATION-MEDIATED CONDITIONS OF THE EYE  
Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal...
US20130017244 Sustained release intraocular implants and related methods  
Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months....
US20140228333 METHODS FOR INHIBITING MUSCLE ATROPHY  
In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The compound can modulate the expression...
US20140154275 GENE EXPRESSION MARKERS FOR CROHN'S DISEASE  
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of...
US20110033486 GENE EXPRESSION MARKERS FOR CROHN'S DISEASE  
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of...
US20110280799 NANOCELLS FOR DIAGNOSIS AND TREATMENT OF DISEASES AND DISORDERS  
The present invention relates to novel nanocell compositions and their use in imaging, diagnostic and treatment methods. In one embodiment, nanocells tailored for imaging methods comprise a...
US20100047198 Textile Scenting  
A perfume-containing PIT emulsion which is suited to contribute to an excellent and long-lasting scenting of textiles during the use of a dryer. The PIT emulsion is simple for the user to handle...
US20120004204 Methods for treating sexual dysfunction while decreasing cardiovascular risk  
Methods for treating female sexual dysfunction are provided. In particular, methods for treating a woman having HSDD by administering to the woman a therapeutically effective amount of an...
US20110176994 Buoyant Polymer Particles for Delivery of Therapeutic Agents to the Central Nervous System  
The invention provides compositions and methods for treating a subject who has suffered from a central nervous system disorder. More particularly, the invention provides sustained polymeric drug...
US20120252720 COMPOSITIONS FOR TREATMENT OF EAR DISORDERS AND METHODS OF USE THEREOF  
The present invention relates to compositions and methods useful for the treatment of ear disorders, administered to a treated ear in the form of a foam or a mousse. Administering a medicament in...
US20140037588 INJECTABLE THERMORESPONSIVE POLYELECTROLYTES  
Provided herein are compositions, devices and systems comprising thermoresponsive, biodegradable elastomeric materials, and methods of use and manufacture thereof.
US20110274740 METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES  
The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering...
US20140200200 Antagonists of CB1 Receptor  
The invention relates to an antagonist of CB1 receptor for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders;...
US20130203712 METHODS FOR INHIBITING MUSCLE ATROPHY  
In one aspect, the invention relates methods for inhibiting or preventing muscle atrophy or increasing muscle mass by providing to a subject in need thereof an effective amount of ursolic acid, a...
US20080015174 Metabolic Disease Treatments  
The invention relates to the use of compounds to treat a number of conditions, such as a pre-diabetes condition, type 1 diabetes, type 2 diabetes, hyperglycemia, insulin resistance and glucose...
US20140213533 METHODS TO DETECT, TREAT AND PREVENT ACUTE CELLULAR REJECTION IN KIDNEY ALLOGRAFTS  
Methods for prevention and treatment of kidney transplant rejection are described that involve determination, analysis and computation of a 3-gene molecular signature of levels of specific RNAs...
US20150044270 SUSTAINED DELIVERY OF THERAPEUTIC AGENTS TO AN EYE COMPARTMENT  
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing...
US20120321719 Sustained Delivery of Therapeutic Agents to an Eye Compartment  
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing...
US20130216623 APPARATUS AND FORMULATIONS FOR SUPRACHORIDAL DRUG DELIVERY  
Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal...