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US20120093892 MINOCYCLINE ORAL DOSAGE FORMS FOR THE TREATMENT OF ACNE  
Minocycline oral dosage forms containing a controlled release carrier are useful for the treatment of acne.
US20100330131 MINOCYCLINE ORAL DOSAGE FORMS FOR THE TREATMENT OF ACNE  
Minocycline oral dosage forms containing a controlled release carrier are useful for the treatment of acne.
US20140323391 BIOMARKERS FOR THE MOLECULAR CLASSIFICATION OF BACTERIAL INFECTION  
Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.
US20140314798 METHOD TO MEASURE INFLAMMATION IN THE CONJUNCTIVA OF PATIENTS WITH TEAR DYSFUNCTION  
The present invention concerns methods and compositions for treatment and determination of the presence or likelihood of an individual to have an ocular surface inflammation. In specific...
US20150132343 SYSTEM AND METHOD FOR THE DETECTION AND TREATMENT OF INFECTION BY A MICROBIAL AGENT ASSOCIATED WITH HIV INFECTION  
A method of treating a patient, comprising administering at least one antibiotic, e.g., doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular bacterial organism present...
US20140073611 METHODS FOR DRUG SCREEN USING ZEBRAFISH MODEL AND THE COMPOUNDS SCREENED THEREFROM  
The disclosure relates to a platform of using zebrafish in screening candidates for treating and/or preventing myopia and keratoconus disease. The disclosure is mainly based on that Lumican, one...
US20140309198 METHOD OF TREATING ACNE  
An improved method for treating acne is described. The method involves 16-week, once daily, oral administration of about 40 mg doxycycline in a pharmaceutical composition containing about 30 mg...
US20130196954 METHOD OF TREATING ACNE  
An improved method for treating acne is described. The method involves 16-week, once daily, oral administration of about 40 mg doxycycline in a pharmaceutical composition containing about 30 mg...
US20150139946 DETECTING MUTATIONS IN DISEASE OVER TIME  
Provided is a method for monitoring a gene mutation associated with a cancer in a patient over time. Also provided is a method of selecting and/or applying treatment or therapy for a subject.
US20150224211 LEUKOCYTES AS DELIVERY CELLS FOR IMAGING AND DISEASE THERAPY  
Theranostic methods are described herein, which are useful in diagnosing and/or treating infection, inflammation, and/or cancer. The methods utilize naturally-occurring leukocytes for in situ...
US20140121188 COMPOSITIONS FOR THE IMPROVED TREATMENT OF ACNE AND RELATED DISORDERS  
Methods of treatment and dosage regimes using hydrophobic gel or foam composition comprising a tetracycline antibiotic in treating or alleviating a disorder including, acne, acne related symptoms,...
US20140187611 MITOCHONDRIAL RIBOSOMAL PROTEINS AS AGING REGULATORS  
The present invention relates to methods of increasing lifespan, delaying aging, and/or preventing or treating an age-related disease or a mitochondrial disease in a subject, comprising inducing a...
US20120046249 METHODS OF REDUCING THE RISK OF CARDIOVASCULAR DISEASE IN POSTMENOPAUSAL WOMEN  
The present invention features materials and methods for reducing the risk of cardiovascular disease in postmenopausal or perimenopausal women. More specifically, these methods can be used in...
US20140349977 EPIGENETIC MARKERS FOR DETECTION OF AUTISM SPECTRUM DISORDERS  
Methods for determining if a patient has, or is at risk of having, and autism spectrum disorder by detecting epigenetic changes in the genome of the patient. For example, a method can comprise...
US20120181201 Topical Formulation Containing a Tetracycline and a Method of Treating Skin Infections Using the Same  
A topical formulation comprising a tetracycline comprises two separate parts: (i) a first part comprising a tetracyline in solid form suspended in a first vehicle; and (ii) a second part...
US20110256203 POROUS CERAMIC SCAFFOLD HAVING AN ORGANIC/INORGANIC HYBRID COATING LAYER CONTAINING BIOACTIVE FACTOR AND METHOD THEREOF  
A method for manufacturing a porous ceramic scaffold having an organic/inorganic hybrid composite coating layer containing a bioactive factor is disclosed. The method includes; forming a porous...
US20140206636 METHODS OF DIAGNOSING AND TREATING SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) AND SIBO-RELATED CONDITIONS  
Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia,...
US20130156790 COMPOUNDS AND USES THEREOF TO INDUCE AN IMMUNOGENIC CANCER CELL DEATH IN A SUBJECT  
The present invention relates to the fields of genetics, immunology and medicine. The present invention more specifically relates to in vitro or ex vivo methods for determining the susceptibility...
US20120329760 RNASE 7 AS A MARKER FOR INFECTION  
Methods of identifying a subject having a urinary tract infection using RNase 7 are described. The methods include providing a test sample of urine from the subject, determining the level of RNase...
US20150202349 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BONE VOIDS AND OPEN FRACTURES  
The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone...
US20140100200 METHODS OF TREATING ACNE  
A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially...
US20120108552 METHODS OF TREATING ACNE  
A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially...
US20150057254 ONCE DAILY FORMULATIONS OF TETRACYCLINES  
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent...
US20140072626 ONCE DAILY FORMULATIONS OF TETRACYCLINES  
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent...
US20110319368 Once daily formulations of tetracyclines  
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent...
US20110294759 Once daily formulations of tetracyclines  
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent...
US20110288056 Once daily formulations of tetracyclines  
Disclosed are once-daily formulations containing tetracyclines, especially doxycycline. Such formulations are useful, for instance, for the treatment of collagenase destructive enzyme-dependent...
US20150104505 COATED PHARMACEUTICAL CAPSULE DOSAGE FORM  
Pharmaceutical compositions in unit dose form comprising a hard or soft capsule containing a fill consisting of one or more inert ingredients, and one or more coatings on the capsule, wherein at...
US20110207706 Methods for Treating Spinal Muscular Atrophy Using Tetracycline Compounds  
Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described.
US20120220555 Methods of Simultaneously Treating Ocular Rosacea and Acne Rosacea  
A method for simultaneously treating ocular rosacea and acne rosacea in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is...
US20130005693 Method for Reducing Levels of Disease Associated Proteins  
The subject invention concerns the reduction of protein aggregation in the neurons of a mammal through the use of a ketogenic treatment such as a ketogenic diet, a physical training regimen and/or...
US20130288951 COMPOSITIONS AND METHODS FOR COATING IMPLANT SURFACES TO INHIBIT SURGICAL INFECTIONS  
Infection-inhibiting compositions suitable for coating surfaces of implantable medical implants, including compositions and devices for coating medical devices in the operating room prior to...
US20130109617 SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF BACILLUS ANTHRACIS INFECTIONS  
Methods and compositions for the treatment of Bacillus anthracis infections are described.
US20110059925 METHODS FOR IMPROVING LID MARGIN AND TEAR FILM FUNCTION AND TREATMENT OF LID MARGIN DISEASE USING TETRACYCLINE FAMILY ANTIBIOTICS  
The present invention provides a mucoadhesive broad spectrum antibiotic with anti-inflammatory characteristics with strong tissue penetration for improving lid margin function and the treatment of...
US20120021038 COATING COMPOSITION  
A wound spacer device comprising multiple beads connected by non-absorbable suture material is disclosed. The device can be applied, for example, by a first responder to an injured individual, or...
US20140221320 TOPICAL MINOCYCLINE OINTMENT FOR SUPPRESSION OF ALLERGIC SKIN RESPONSES  
The method of the present application is directed towards a method for suppressing an allergic response in response to an allergic trigger. This method comprises the following steps; applying,...
US20150110849 ANTIMICROBIAL ACCESSORY FOR AN IMPLANTABLE MEDICAL DEVICE  
An antimicrobial accessory may include a pressure sensitive adhesive and an antimicrobial mixed in the pressure sensitive adhesive. In some examples, an antimicrobial accessory may include at...
US20120064145 WOUND DRESSING  
The present invention discloses a wound dressing which may be a double-layer wound dressing, comprising a polymer material layer in combination with anti-infective antibiotics or anti-infective...
US20110280841 Electroprocessing in Drug Delivery and Cell Encapsulation  
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more...
US20120088739 METHOD FOR TREATING MEIBOMIAN GLAND DISEASE  
A method for treating a patient having meibomian gland disease, ocular irritation associated with delayed tear clearance, or recurrent corneal epithelial erosion, is disclosed. Preferably, the...
US20110039805 METHOD FOR TREATING MEIBOMIAN GLAND DISEASE  
A method for treating a patient having meibomian gland disease, ocular irritation associated with delayed tear clearance, or recurrent corneal epithelial erosion, is disclosed. Preferably, the...
US20140349938 METHODS OF DIAGNOSING AND TREATING AMYOTROPHIC LATERAL SCLEROSIS  
The invention features methods of diagnosing a subject as having, or at risk of developing ALS by determining the frequency of Gems in cells obtained from the subject. These methods include...
US20130202705 ALCOHOL-RESISTANT FORMULATIONS  
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing a high water-soluble, high dose...
US20110171232 METHODS OF TREATING AUTOIMMUNE DISEASES CAUSED BY SMALL INTESTINAL BACTERIAL OVERGROWTH  
Disclosed is a method of diagnosing autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, which involves detecting the presence of small intestinal bacterial overgrowth...
US20150111834 RECIPE FOR IN-SITU GEL, AND IMPLANT, DRUG DELIVERY SYSTEM FORMED THEREBY  
The disclosure provides a recipe for in-situ gel, formed by dissolving at least one polymer and at least one gel prevention agent in a polar solvent to form a solution and placing the solution in...
US20130344079 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING PHENYLKETONURIA (PKU)  
A method of diagnosing Phenylketonuria (PKU) in a subject in need thereof is disclosed. The method comprises detecting phenylalanine fibrils in a tissue of the subject, wherein a presence or level...
US20120022026 METHOD OF TREATING CANCER  
The present invention relates to a method of treating or preventing hyperproliferative disease in a body tissue of a subject, comprising the steps of administering to a subject in need thereof a...
US20150038851 MEIBOMIAN GLAND DYSFUNCTION  
Provided herein are methods of diagnosing meibomian gland dysfunction (MGD), determining the severity of meibomian gland dysfunction in a subject, evaluating efficacy of treatment of MGD in a...
US20150025025 Immuno-modulators for treating functional epithelial syndromes  
An immuno-modulating composition including an organic compound and a metal chelator or a metal ion. Also disclosed is a method for treating a disease or condition in man and animals with the...
US20140274969 USE OF MINOCYCLINE FOR THERAPEUTIC TREATMENT OF ACUTE SPINAL CORD INJURIES  
A dosing regime for providing therapy for a neurological trauma such as spinal cord injury in a human subject. The dosing regime comprises intravenous administration of a plurality of minocycline...