Matches 1 - 50 out of 395 1 2 3 4 5 6 7 8 >


Match Document Document Title
US20150071879 Stabilization of Aqueous Compositions of Proteins with Displacement Buffers  
An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least...
US20150023977 PROTEIN FORMULATIONS AND METHODS OF MAKING SAME  
The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may...
US20140051635 COMBINATION THERAPY FOR TREATMENT OF CANCER  
The present invention relates to methods and compositions for treating cancer. Some embodiments include methods comprising increasing expression of a nucleic acid encoding secreted protein acidic...
US20130216479 SITE-SPECIFIC CHEMICAL MODIFICATION OF PROTEINS AT THEIR N-TERMINI, ENABLING THE FORMATION OF HOMOGENEOUS ADDUCTS  
Site-specific modifications of proteins at their N-termini are provided. In particular, a chemical modification of proteins at their N-termini via a transamination reaction to form homogeneous...
US20110286937 SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME  
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
US20140308293 RECONSTITUTION METHOD FOR HIGH CONCENTRATION DRY PROTEIN FORMULATIONS  
The present invention relates to the provision of a novel method for the reconstitution of dry formulations comprising biomolecules, and in particular, to dry protein formulations, and to...
US20150004102 NANOPARTICLES COMPRISING A VEGETABLE HYDROPHOBIC PROTEIN AND A WATER MISCIBLE NON-VOLATILE ORGANIC SOLVENT AND USES THEREOF  
The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, said nanoparticles being based on a vegetable hydrophobic protein, particularly zein,...
US20140079788 METHODS OF TREATMENT OF PANCREATIC CANCER  
The present invention provides methods and compositions for treating pancreatic cancer in an individual who has been previously treated for pancreatic cancer (e.g., gemcitabine-based therapy) by...
US20130202709 METHODS OF TREATMENT OF PANCREATIC CANCER  
The present invention provides methods and compositions for treating pancreatic cancer in an individual who has been previously treated for pancreatic cancer (e.g., gemcitabine-based therapy) by...
US20150079181 METHODS AND COMPOSITIONS FOR TREATING RECURRENT CANCER  
The present invention provides methods of treating recurrent cancer (such as recurrent ovarian, peritoneal, or fallopian tube cancer) in an individual, comprising administering to the individual...
US20120195883 MONOCOT SEED PRODUCT COMPRISING A HUMAN BLOOD PROTEIN  
The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and...
US20140072643 METHODS OF TREATING CANCER  
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an...
US20120164087 Human Serum Albumin-Based Topical Ointment for Treatment of Acne, Psoriasis, Egfr-Induced Toxicity, Premature Skin Aging and Other Skin Conditions  
Dermatological compositions and method for treating psoriasis, eczema, acne and like skin conditions for sanitization pharmaceutical compounding and protection of the skin from extreme...
US20150023912 COMBINATIONS OF ALBUMIN-BASED DRUG DELIVERY SYSTEMS  
The present invention relates to a composition comprising at least two different albumin-based drug delivery systems, as well as to a pharmaceutical composition comprising said composition.
US20120309682 SUPPRESSION OF CANCER METASTASIS  
Methods are provided for suppressing cancer metastasis. Cancer metastasis is the most common cause of treatment failure and death in cancer patients. Tumor cell invasion and/or migration can be...
US20130071462 Drug Delivery Systems and Applications  
Certain embodiments of the invention include medical materials and methods comprising a biodegradable hydrophilic hydrogel comprising dispersed lipophilic particles that comprise a therapeutic...
US20130136796 Acellular Bioabsorbable Tissue Regeneration Matrices  
The present invention provides methods and compositions useful in the regeneration of damaged, lost and/or degenerated tissue in humans and animals. In certain embodiments, the present invention...
US20140065170 DIAGNOSIS AND TREATMENT OF PREECLAMPSIA  
The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of...
US20130338074 FUSION PROTEIN COMPRISING ALBUMIN AND RETINOL-BINDING PROTEIN  
There is provided a fusion protein comprising albumin and retinol-binding protein, which can be used for preventing or treating fibrotic diseases. The fusion protein, in which albumin and a...
US20120189668 HYDROGEL BIOSCAFFOLD AND COATING FOR BONE AND TOOTH REPAIR  
Hydrogel compositions that include an albumin/N-acetyl cysteine solution and an aqueous suspension of calcium salts or mixture of calcium and magnesium salts are described. Also described are...
US20110065642 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE AND/OR CORNEAL AND CONJUNCTIVAL LESION  
The present invention provides a pharmaceutical composition for the treatment of dry eye and/or corneal and conjunctival lesion which comprises a recombinant human serum albumin produced by a...
US20150147320 Ophthalmic Drug Delivery System Containing Phospholipid and Cholesterol  
An ophthalmic drug delivery system that contains phospholipid and cholesterol for prolonging drug lifetime in the eyes.
US20140031285 PHOTODEGRADABLE GROUPS FOR TUNABLE POLYMERIC MATERIALS  
Here, we present a photodegradable microparticle system that can be employed to entrap and deliver bioactive proteins to cells during culture. By using a photosensitive delivery system,...
US20110250240 IMMUNE ENHANCING COMPOSITIONS AND METHODS OF USE THEREOF  
A method of administering parenterally, particularly intramuscularly, glutamine and cystine and glycine plus selenium; or lactalbumin plus selenium; or lactalbumin and glutamine and cystine and...
US20130261054 METHODS FOR TREATMENT OF NEPHROTIC SYNDROME AND RELATED CONDITIONS  
The present disclosure provides a method for treating and/or preventing nephrotic syndrome, such as but not limited to MCD and MN, and conditions related to nephrotic syndrome, such as but not...
US20140194354 Methods for Treatment of Nephrotic Syndrome and Related Conditions  
The present disclosure provides a method for treating and/or preventing nephrotic syndrome, such as but not limited to minimal change disease and membranous nephropathy, and conditions related to...
US20150044280 TREATMENT METHODS USING ADENOVIRUS  
The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor or inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient...
US20140363482 Bioerodible Sustained Release Drug Delivery Systems  
The present invention relates to sustained release drug delivery systems, medical devices incorporating said systems, and methods of use and manufacture thereof. The inventive systems feature...
US20150023960 Compositions and Methods of Use for Treating Metabolic Disorders  
Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
US20120093798 Methods for Treatment of Stroke or Cerebrovascular  
Methods of using an ETB receptor agonist, such as IRL-1620, for the treatment of stroke or cerebrovascular accidents are disclosed. The ETB receptor agonist is used alone or in combination with a...
US20130012443 METHODS OF TREATMENT OF CENTRAL NERVOUS SYSTEM HEMORRHAGE USING PROTOPORPHYRIN IX-FE COMPOUNDS  
Described herein are methods and compositions relating to treatment of tissue damage resulting from a central nervous system (CNS) hemorrhage with a protoporphyrin IX-Fe compound.
US20140080760 COMBINATION THERAPY FOR TREATMENT OF CANCER  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
US20140056986 METHODS OF TREATING BLADDER CANCER  
The present invention provides methods and compositions for treating bladder cancer, including metastatic bladder cancer and non-muscle-invasive bladder cancer, by administering a composition...
US20130266659 METHODS OF TREATING BLADDER CANCER  
The present invention provides methods and compositions for treating bladder cancer, including metastatic bladder cancer and non-muscle-invasive bladder cancer, by administering a composition...
US20120219589 FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES  
The invention relates to percutaneous administration of drugs and vaccines in form of solid penetrating needles, “injectable needles”, comprising a polymeric matrix resulting from the...
US20110126767 METHODS AND COMPOSITIONS FOR INCREASING THE HATCHABILITY OF HATCHERY EGGS  
The invention relates to a method for hatching of hatchery eggs comprising: (a) treating the egg shell surface with a coating composition comprising a coating agent, to form a coating on the...
US20130195757 SPARC BINDING APTAMERS AND USES THEREOF  
The invention relates to nucleic acid aptamers having the ability to bind human SPARC protein (osteonectin) with specificity. The invention also relates to compositions including such aptamers, as...
US20140161738 HEMOSTATIC FOAM  
The invention discloses a pharmaceutical hemostatic liquid foam base preparation comprising albumin as foaming agent and a fibrinogen precipitating substance and optionally a coagulation inducing...
US20130323246 USE OF MDL-1 ANTAGONISTS TO TREAT SPONDYLARTHROPATHY  
The invention provides methods for treating spondylarthropathy with antagonists of MDL-1 alone or in combination with IL-23 antagonists.
US20130101669 LOGICAL ENZYME TRIGGERED (LET) LAYER-BY-LAYER NANOCAPSULES FOR DRUG DELIVERY SYSTEM  
Nanocapsule compositions comprising a calcium carbonate core surrounded by a bilayer or bilayers of polystyrene sulfonate and poly(allylamine hydrochloride). The poly(allylamine hydrochloride) is...
US20140369993 STABILISED PROTEIN COMPOSITIONS BASED ON SEMIFLUORINATED ALKANES  
The invention provides novel compositions of bioactive polypeptides and proteins with improved stability and shelf-life. The compositions are based on liquid vehicles selected from semifluorinated...
US20150079156 LIPOSOMAL DELIVERY SYSTEM  
The present invention is directed to a liposomal delivery system comprising defined lipid components, including dimethyldioctadecylammonium and other lipid components and a stabilizing agent,...
US20130244940 DESIGNED REPEAT PROTEINS BINDING TO SERUM ALBUMIN  
New designed repeat proteins with binding specificity for serum albumin are described, as well as nucleic acids encoding such serum albumin binding proteins, pharmaceutical compositions comprising...
US20150165026 SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF  
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at...
US20150190364 SPARC AND METHODS OF USE THEREOF  
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying...
US20150141343 SPARC AND METHODS OF USE THEREOF  
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying...
US20130178423 SPARC AND METHODS OF USE THEREOF  
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying...
US20130178422 SPARC AND METHODS OF USE THEREOF  
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying...
US20140066378 Multivalent Heteromultimer Scaffold Design and Constructs  
Provided herein are multifunctional heteromultimer proteins. In specific embodiments is a heteromultimer comprising: at least two polypeptide constructs, each polypeptide construct comprising at...
US20100297247 Aqueous-Core Lipid Nanocapsules for Encapsulating Hydrophilic and/or Lipophilic Molecules  
The invention relates to a composition comprising in an aqueous phase, particles having a diameter in the range of 20 to 500 nm, said particles containing:—an oil phase;—in said oil phase,—an...

Matches 1 - 50 out of 395 1 2 3 4 5 6 7 8 >