Matches 1 - 30 out of 30


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US20070292473 DEVICE FOR LOCAL ADMINISTRATION OF SOLID OR SEMI-SOLID FORMULATIONS AND DELAYED-RELEASE FORMULATIONS FOR PROPOSAL PARENTERAL ADMINISTRATION AND PREPARATION PROCESS  
A method for implanting or inserting a solid or semisolid formulation containing at least one active principle uses a device comprising one part set inside the body of the patient and which...
US20060257359 Modifying macrophage phenotype for treatment of disease  
The present invention provides compositions and methods for modulating one or more phenotypes of a macrophage-related cell, e.g., a macrophage. The invention further provides methods of treating...
US20060263351 Methods and compositions for protection against thrombolysis associated reperfusion injury  
The invention relates to products and methods for reducing cerebral hemorrhage and edema, which can be negative side-effects of thrombolytic therapies with tissue plasminogen activator (tPA)...
US20110028397 Use of Urokinase Type Plasminogen Activator Inhibitors for the Treatment of Corneal Disorders  
The invention concerns the use of inhibitors of the urokinase type of plasminogen activator (uPA) appearing in the anterior segment of the eye, for the treatment and prevention of corneal ulcers...
US20050123507 Formulations for coated microprojections having controlled solubility  
The invention provides for a formulation for coating one or more microprojections using a non-volatile counterion to improve solubility of a biologically active agent. The invention also includes...
US20070293436 Cytoprotective thereapeutic agents for the prevention of reperfusion injury following ischemic stroke  
The present invention relates generally to the use of γ-glutamyl antioxidants, particularly γ-glutamyl-cysteine, as cytoprotective agents to prevent reperfusion injury (i.e., hemorrhagic...
US20070196272 ORAL DELIVERY OF THERAPEUTIC AGENTS USING TIGHT JUNCTION AGONISTS  
The present invention provides compositions and methods for the administration of the compositions to mammals. The compositions comprise therapeutic agents and an intestinal absorption enhancing...
US20050084511 Lumen formation-inducible material and instrument to be inserted into the body  
The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This...
US20080019910 Cancer Treatment and Cancer Treatment Efficacy Prediction by Blocking and Detecting Protease Inhibitors  
Disclosed is a method for improving cancer therapy that relies on induction of apoptosis in malignant cells. It has been found that docking of protease inhibitors PAI-1 and TIMP-1 renders...
US20060034847 Methods of treating a subject for a condition  
Methods are provided for treating a subject for at least one condition that includes inflammation, a blood clotting condition and autonomic nervous system dysfunction such as adrenergia, e.g.,...
US20080207508 Treatment of Fungal and/or Protist Infections  
The present invention relates to the use of a polypeptides, comprising repeats of a peptide derived from a Heparan Sulphate Proteoglycan (HSPG) receptor binding region of an apolipoprotein, for...
US20060210532 Means and methods for the recruitment and identification of stem cells  
Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including...
US20090054336 Binding Agent  
Agents which bind to cell surface receptors; methods to manufacture such agents; therapeutic compositions comprising such agents; and screening methods to identify novel agents.
US20080038361 Water-Soluble Nanoparticles Stabilized with Multi-Functional Group Ligands and Method of Preparation Thereof  
Disclosed are water-soluble nanoparticles. The water-soluble nanoparticles are each surrounded by a multifunctional group ligand including an adhesive region, a cross linking region, and a...
US20070134199 Formulation for a protein pharmaceutical without added human serum albumin (HSA)  
A composition for stabilization of protein agents in pharmaceuticals, the composition comprising the following two constituents: a) a surface active substance, in particular a non-ionic detergent...
US20060002963 Use of emulsions for intra and periocular injections  
A method for treating eye diseases by injecting intraocularly or periocularly a composition comprising an emulsion and optionally at least a pharmaceutical active ingredient.
US20080138277 Delivery systems and methods for diagnosing and treating cardiovascular diseases  
The invention relates to the treatment and prevention of atherosclerosis and cardiovascular diseases associated with atherosclerosis. The invention further relates to methods of diagnosing...
US20050232925 Protease activity of thrombin inhibits angiogenesis  
The present invention features pharmaceutical compositions and methods to inhibit angiogenesis, with implications to cancer therapy. These methods are based on the discovery that activated...
US20090305961 Novel chimeric plasminogen activators and their pharmaceutical use  
The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein...
US20050245444 Method of using recombinant human antithrombin for neurocognitive disorders  
The present invention provides for the production of recombinant human antithrombin (rhAT) for the treatment or prophylaxis of neurocognitive disorders typically associated with major surgical...
US20100210525 COMBINED PREPARATION OF A THIAZIDE DIURETIC AND A LOOP DIURETIC  
The specific molecular basis of the interaction between talin and integrin β3 has been defined. This specific interaction provides a new therapeutic target; agents that can disrupt this specific...
US20080171696 Pharmacodynamically enhanced therapeutic proteins  
Compositions containing an N-linked oligosaccharide having little or no terminal sialic acid residues which is attached to a therapeutic protein that is bonded to a glycol polymer.
US20070196416 Pharmaceutical compositions with enhanced stability  
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention...
US20070172422 Exponential pattern recognition based cellular targeting compositions, methods and anticancer applications  
The present invention relates to the compositions, methods, and applications of a new approach to pattern recognition based targeting by which an exponential amplification of effector response can...
US20060069035 Peptide for regulation of urokinase plasminogen activator and method of optimizing therapeutic efficacy  
The present invention relates to compositions of the polypeptide EEIIMID and one or more fibrinolytic agents selected from the group consisting of scuPA, tPA, uPA, tcuPA, streptokinase, rt-PA,...
US20070141145 HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME  
The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently linked to the polymeric carrier. The...
US20090069232 GLYCOSYLATION OF MOLECULES  
Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered...
US20070196269 Pharmaceutical composition  
The invention concerns a pharmaceutical composition comprising at least one stimulator of the immune cell functions and at least one substance inhibiting the cell proliferation and/or inducing...
US20050158392 Lipophilic-coated microparticle containing a protein drug and formulation comprising same  
A solid lipophilic microparticle having an average particle size ranging from 0.1 to 200 μm, comprising a lipophilic substance, hyaluronic acid or an inorganic salt thereof and an active...
US20070123457 Carrier chimeric proteins, targeted carrier chimeric proteins and preparation thereof  
A chimeric carrier protein having a multimerization domain and at least one drug attached thereto via a spacer is disclosed. The protein may be targeted by associating at least one amino acid...

Matches 1 - 30 out of 30