Matches 1 - 50 out of 177 1 2 3 4 >


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US20050148512 Medical implants and fibrosis-inducing agents  
Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between...
US20110123577 Method Of Delivering Stable Topical Drug Compositions  
A method of delivering a drug composition comprises providing a carrier having a phosphatidylcholine component and a drug entrapped therein, and applying the composition to the skin for...
US20110046606 Catheter injectable depot compositions and uses thereof  
Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an...
US20100292139 TOPICAL DRUG DELIVERY USING PHOSPHATIDYLCHOLINE  
The present invention relates to compositions and methods for transdermal drug delivery comprising formulating a phosphatidylcholine carrier composition containing the drug and applying the...
US20070196416 Pharmaceutical compositions with enhanced stability  
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention...
US20070141145 HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME  
The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently linked to the polymeric carrier. The...
US20060210599 High viscosity liquid controlled delivery system and medical or surgical device  
The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a...
US20060105955 Topical drug delivery using phosphatidylcholine  
The present invention relates to compositions and methods for transdermal drug delivery comprising formulating a phosphatidylcholine carrier composition containing the drug and applying the...
US20050181004 Intravascular devices and fibrosis-inducing agents  
Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order...
US20050177103 Intravascular devices and fibrosis-inducing agents  
Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order...
US20050147562 Medical implants and fibrosis-inducing agents  
Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between...
US20140315795 Compositions and Methods for Selective Delivery of Oligonucleotide Molecules to Cell Types  
The invention provides a conjugate comprising (i) a nucleic acid which is complementary to a target nucleic acid sequence and which expression prevents or reduces expression of the target nucleic...
US20120077745 Method of stimulating the motility of the gastrointestinal system using growth hormone secretagogues  
The present invention relates to a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders or...
US20090163419 Human growth hormone aqueous formulation  
A stable pharmaceutically acceptable aqueous formulation containing human growth hormone, a buffer, a non-ionic surfactant, and, optionally, a neutral salt, mannitol, or, a preservative, is...
US20070173450 PROCESS FOR THE SYNCHRONIZATION OF OVULATION FOR TIMED BREEDING WITHOUT HEAT DETECTION  
A method for synchronizing ovulation in sows and gilts by a single injection of hormones is disclosed. A hormone, gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), follicle...
US20070099820 Polymer-drug conjugates  
A conjugate that includes a drug covalently linked to a polymer. Upon administration, the conjugate is digested by an enzyme that is present at the site of administration thereby releasing a...
US20060275353 Stable topical drug delivery compositions  
A method of delivering a drug composition comprises providing a carrier having a phosphatidylcholine component and a drug entrapped therein, and applying the composition to the skin for...
US20060153801 Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same  
A non-polydispersed mixture of conjugates in which each conjugate in the mixture comprises a drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may...
US20060127469 Methods of delivering stable topical drug compositions  
A method of delivering a drug composition comprises providing a carrier having a phosphatidylcholine component and a drug entrapped therein, and applying the composition to the skin for...
US20060093557 Particulate composition  
Nanoparticles are prepared from a colloidal system comprising a continuous phase and micelles, the micelles comprising surfactant material. A microemulsion is formed by admixing the colloidal...
US20050069591 Injectable, oral, or topical sustained release pharmaceutical formulations  
Pharmaceutical formulations and methods are provided for the sustained delivery of a pharmaceutical agent to a patient by injection, by oral administration or by topical administration. The...
US20050009847 Compounds and methods for increasing neurogenesis  
The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with intracellular cAMP elevating agents and intracellular Ca2+ elevating agents. Novel agents for...
US20150374656 Compositions and methods of use of phorbol esters  
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of cytopathic diseases. Cytopathic diseases may be caused by a variety means...
US20140072531 METHOD FOR PREPARING MICROPARTICLES WITH REDUCED INITIAL BURST AND MICROPARTICLES PREPARED THEREBY  
A method for preparing polymer microparticles with a reduced initial burst, and the polymer microparticles prepared thereby, the method including: contacting polymer microparticles with an alcohol...
US20130230598 SUSTAINED-RELEASE COMPOSITION OF DRUGS ENCAPSULATED IN MICROPARTICLES OF HYALURONIC ACID  
A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased...
US20120329714 Prolactin Induced Increase in Neural Stem Cell Numbers  
The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ,...
US20110020458 SUSTAINED-RELEASE COMPOSITION OF DRUGS ENCAPSULATED IN MICROPARTICLES OF HYALURONIC ACID  
A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased...
US20070248686 Colloidal suspension of submicronic particles as vectors for active principles and method for preparing same  
A suspension of vector particles (PV) based on polyamino acids and have a mean hydrodynamic diameter between 30 and 120 nm, and an insulin load factor of from 5 to 25% of associated insulin volume...
US20060188496 Intranasal administration of active agents to the central nervous system  
A method for delivering a polypeptide to the central nervous system of a mammal is provided. The method involves attaching the polypeptide to an antibody or an antibody fragment and administering...
US20140329750 Growth Hormones with Prolonged In-Vivo Efficacy  
The present invention relates to polypeptide compound optimized for subcutaneous administration, exemplified by growth hormone conjugates having a linker providing non-covalent binding to albumin.
US20070219131 COMPOSITIONS CAPABLE OF FACILITATING PENETRATION ACROSS A BIOLOGICAL BARRIER  
This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium. The invention also relates...
US20050031549 Compositions and methods for enhanced mucosal delivery of growth hormone  
Pharmaceutical formulations are described comprising at least one growth hormone and one or more intranasal delivery-enhancing agents for enhanced nasal mucosal delivery of the growth hormone. In...
US20120283172 MODIFIED PORCINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES  
Modified porcine somatotropin polypeptides and uses thereof are provided.
US20070275889 Gene Expression Technique  
The present invention provides a method for producing heterologous protein comprising: (a) providing a host cell comprising a 2 μm-family plasmid, the plasmid comprising a gene encoding a protein...
US20050032702 Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells  
Use of a substance that upon administration will lead to increased concentrations of growth hormone, such as growth hormone, a functionally equivalent analogue thereof or a substance that will...
US20070065404 Uses of humans zven proteins and polynucleotides  
The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility...
US20070191283 Method of stimulating the motility of the gastrointestinal system using growth hormone secretagogues  
The present invention relates to a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders or...
US20060166871 Medical compositions containing ghrelin  
It is provided a pharmaceutical composition stably containing ghrelin or its derivative, which is an endogenous growth hormone secretagogue (GHS) to a growth hormone secretagogue-receptor (GHS-R),...
US20060062758 Tight junction modulator peptide PN159 for enhanced mucosal delivery of therapeutic compounds  
Compositions and methods are provided that include a biologically active agent and a permeabilizing agent effective to enhance mucosal delivery of the biologically active agent in a mammalian...
US20050152980 Pharmeutical microparticles  
Microparticles consisting of (a) a matrix with a mixture of (a1) at least one hydrophobic, biologically degradable polymer and (a2) optionally at least one water-soluble polymer, (b) a...
US20050118272 Micronized pharmaceutical or nutraceutical powder with immediate release  
The invention concerns a micronized pharmaceutical or nutraceutical powder with immediate release having a grain size distribution of not more than 100 μm, and comprising the combination of at...
US20050261201 Method of reducing C-reactive protein using growth hormone secretagogues  
The present invention relates to a method of reducing C-reactive protein in a subject in need of treatment thereof, wherein the subject is at risk of having or the subject has already had a...
US20110123625 Compositions of Less Immunogenic and Long-Circulating Protein-Lipid Complexes  
Provided are lipidic particles comprising phosphatidylcholine, phosphatidylinositol and cholesterol. Also provided are compositions comprising the lipidic particles and having associated therewith...
US20100247594 DELIVERY OF DRY FORMULATIONS OF OCTREOTIDE  
Methods and devices are described for delivering octreotide to a patient, comprising implanting a controlled release composition for delivering octreotide, wherein the composition does not require...
US20080226730 PARTICLES FOR INHALATION HAVING RAPID RELEASE PROPERTIES  
The invention generally relates to formulations having particles comprising phospholipids, bioactive agent and excipients and the pulmonary delivery thereof. Dry powder inhaled insulin...
US20070243192 Growth hormone receptor antagonist cancer treatment  
The present invention provides methods and compositions for treating tumorigenic cells (e.g., mammary progenitor cancer cells), with growth hormone receptor antagonists (e.g., Pegvisomant), as...
US20060193825 Pharmaceutical formulations for sustained drug delivery  
The present invention provides pharmaceutical formulations comprising a solid ionic complex of a polypeptide having an isoelectric point lower than physiological pH and an anionic carrier...
US20050025806 Sustained release pharmaceutical composition  
A sustained release delivery apparatus including a silicone support material formed from a methyl-vinyl siloxane polymer including a fumed silica as a reinforcing filler; a pharmaceutically active...
US20140162944 CONTROLLED RELEASE PEPTIDE FORMULATIONS  
The present invention relates to compositions forming a low viscosity mixture of: a) 20-80 wt. % of at least one diacyl glycerol and/or a tocopherol; b) 20-80 wt. % of at least one phosphatidyl...
US20080200383 Pharmaceutical Formulations Comprising Incretin Peptide and Aprotic Polar Solvent  
The present disclosure is directed to stable pharmaceutical formulations and uses thereof.

Matches 1 - 50 out of 177 1 2 3 4 >