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US20120022023 |
Hydraulic Cements, Methods and Products
Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or... |
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US20120322767 |
FORMULATIONS OF BISPHOSPHONATES AND VITAMIN D SUIUTABLE FOR INTERMITTENT INTRAMUSCULAR AND SUBCUTANEOUS ADMINISTRATION
Compositions for pharmaceutical use are described, comprising bisphosphonates and vitamin D in high concentration, destined to the intramuscular and subcutaneous intermittent administration for... |
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US20130059820 |
INOSITOL PYROPHOSPHATES, AND METHODS OF USE THEREOF
The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm... |
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US20060287241 |
Combination comprising N-(3-methoxy-5-methylpyrazin-2yl)-2-(4-[1,3,4-oxadiazol-2-y1]pyridine-3-sulphonamide and an lhrh analogue and/or bisphosphonate
A combination, comprising N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-y
l]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, and an LHRH analogue and/or... |
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US20150018316 |
Compounds, Methods, and Treatments for Abnormal Signaling Pathways for Prenatal and Postnatal Development
The present invention relates to prevention of congenital deformations. The invention further relates to cancer inhibition and prevention. The invention further relates to methods and compositions... |
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US20110218176 |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
The present invention relates to prevention of congenital deformations. The invention further relates to cancer inhibition and prevention. The invention further relates to methods and compositions... |
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US20110104301 |
METHODS OF REDUCING PAIN AND INFLAMMATION
Provided herein are methods of treating or preventing pain and/or inflammation in a subject comprising administering to the subject a transient receptor potential (TRP) ion channel inhibitor. |
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US20120040896 |
COMPOSITIONS, METHODS AND USES FOR MODULATION OF BRCA 1
Embodiments of the present invention generally relate to methods, compositions and uses for diagnosis and treatment of cancer. Certain embodiments report methods and compositions for diagnosing... |
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US20130316991 |
Biologically active supplements and process of its production
The invention relates to dietary and prophylactic biologically active food supplements (BAS), in particular, from raw plant material and methods for their production; it can be used as a food... |
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US20050202083 |
Storage stable tablets of fosinopril sodium
The technical field of the present invention relates to the selection of lubricants to provide a storage stable tablet of fosinopril, alone or in combination with a diuretic, as well as processes... |
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US20130337022 |
PHARMACEUTICAL DOSAGE FORM
A pH responsive and mucoadhesive pharmaceutical dosage form for the release of a pharmaceutically active agent is described. The dosage form includes a mucoadhesive layer for site-specific... |
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US20140274966 |
Drink Product Containing Genistein and Use Thereof
A drink product having as an active ingredient genistein and an inositol hexaphosphate and/or an unphosphorylated inositol and optionally additional inositol (unphosphorylated as well as... |
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US20140274965 |
Drink Product and Use Thereof
A drink product having as an active ingredient an inositol hexaphosphate and optionally additional inositol moieties. Hexaphosphates for use in the invention include myoinositol hexaphosphate... |
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US20110070224 |
METHODS COMPOSITIONS AND DEVICES UTILIZING STINGING CELLS/CAPSULES FOR DELIVERING A THERAPEUTIC OR A COSMETIC AGENT INTO A TISSUE
A delivery device including at least one stinging capsule and methods of use are described. |
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US20110269675 |
STRONTIUM-CONTAINING COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF NECROTIC BONE CONDITIONS
A method for the treatment and/or prophylaxis of an osteonecrotic bone disease in a mammal in need thereof, such as, e.g., idiopathic or secondary osteonecrosis, avascular bone necrosis,... |
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US20130090371 |
METHODS AND COMPOSITIONS FOR INHIBITION OF BETA2-ADRENERGIC RECEPTOR DEGRADATION
The present invention generally relates to compositions and kits comprising a β2-AR agonist and a modulator of a β2-AR regulator gene, where the modulator of the β2-AR regulator gene inhibits the... |
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US20130289621 |
Drug-Impregnated Encasement
A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity... |
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US20070077267 |
Bioactive composite implants
A composite spinal implant device including collagen and/or synthetic fibers impregnated with a bioactive formulation is disclosed. Also disclosed are methods of making the composite spinal... |
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US20130089604 |
Solid Oral Dosage Form Containing An Enhancer
The invention relates to a solid oral dosage form comprising a pharmaceutically active ingredient in combination with an enhancer which enhances the bioavailability and/or the absorption of the... |
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US20060166937 |
Bisphosphonates for the treatment of atherosclerosis and device comprising them
A method for the treatment of atherosclerosis, in particular atherosclerotic/valve calcification and plaque rupture/stroke, in a patient in need of such treatment, e.g. a patient with aterial or... |
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US20050148521 |
Anti-cancer combination and use thereof
The present invention relates to the surprising discovery that the combination of several agents, each well known for its established role in treating cancer, inflammation, hemostasis, bone... |
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US20140296134 |
METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION
Embodiments include methods for generating a metabolite profile of a stool sample and methods of assessing the status of a subject using the metabolic profile derived from a stool sample. |
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US20070142336 |
Treatment of cancer
The invention relates to the treatment of cancers, in particular, cancers that are resistant to platinum based chemotherapeutic agents. A pharmaceutical composition for the treatment of cancer... |
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US20050176685 |
Method for inhibiting bone resorption with an alendronate and vitamin d formulation
Composition and method for preventing or treating abnormal bone resorption in mammals, the composition characterized as containing, a supplementary effective amount of a non-activated metabolite... |
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US20060046982 |
Orthomolecular medical use of L-citrulline for capillary endothelial protection and adjacent cell protection in neurodegenerative disease
This invention embodies use of exogenous L-citrulline not only for support of capillary endothelial function, by L-citrulline bioconversion to plasma L-arginine to provide more cell substrate for... |
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US20120165296 |
BISPHOSPHONATE-PRODRUGS
The present invention relates to a prodrug, comprising a pharmaceutically and/or diagnostically active compound, and one or more bisphosphonate groups, to a process for producing such a prodrug,... |
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US20070066574 |
MYO-INOSITOL HEXAPHOSPHATE FOR TOPICAL USE
The invention relates to a composition that includes myo-inositol hexaphosphate applied by topical administration for utilisation in the treatment or prevention of a disease associated with the... |
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US20130302448 |
PHYTIN AQUEOUS SOLUTION AND USE OF SAID SOLUTION FOR THE PREPARATION OF A LIQUID NUTRITIONAL SUPPLEMENT OR A COSMETIC COMPOSITION
A phytin aqueous solution including at least one alpha-hydroxylated carboxylic acid and phytin in a solubilized form, preferably in a concentration ranging from 70 g/L to 270 g/L, and in that it... |
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US20050187195 |
Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans
The compounds of formula (I) are hydrophilic aryl phosphate, thiophosphate, and aminophosphate intestinal apical membrane Na-mediated phosphate co-transportation inhibitors. The compounds can be... |
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US20080021001 |
Methods For Treating Arthritic Conditions In Dogs
The present invention relates to a method for eliciting a disease modifying effect on an arthritic condition in a hip or stifle of a canine which comprises administering to the canine a... |
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US20070116778 |
Antibacterial, antiviral, and antifungal nutritional supplement: a combination of natural or neutraceutical compounds shown to have antibacterial, antiviral, and antifungal properties, to help boost the immune system in humans, and to protect against certain biowarfare diseases
Certain compounds have been shown to provide antibacterial, antiviral, and antifungal properties. These compounds can provide some of the beneficial aspects of medicinal antibiotics without... |
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US20060078531 |
Method of prevention and treatment of atherosclerosis, peripheral vascular disease, coronary artery disease, and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease
This invention relates to a method for prevention and treatment of Atherosclerosis, Peripheral Vascular Disease, Coronary Artery Disease, and age-related disorders including Osteoporosis,... |
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US20130184206 |
Selective androgen receptor modulators (SARMs) and uses thereof
Provided herein are compounds that bind to androgen receptors and/or modulate activity of androgen receptors. Also provided are methods for making and using such compounds. Also provided are... |
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US20080075664 |
Control Of Diabetes And Obesity
Provided are methods of increasing resistance to and methods of treating disorders associated with weight gain. Also provided are methods of screening for an agent that prevents or treats a... |
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US20070032457 |
Combination therapy for cancer treatment
The present invention provides methods of treating cancer, the methods generally involving combination therapy. The methods are useful as primary cancer therapy, or as adjuvant therapy. The... |
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US20050009868 |
Retinoid receptor pan-antagonists for stimulating chondrogenesis
The invention relates to methods and compositions for inducing or enhancing chondrogenesis in vivo and/or ex vivo. More specifically, the invention is directed to the use of RAR pan-antagonist... |
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US20150250759 |
COMPOSITION FOR INHIBITION OF CATHEPSIN K
The present invention relates to the a method of inhibiting bone resorption in a mammal in need thereof with an oral pharmaceutical composition comprising a cathepsin K inhibitor, or a... |
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US20140186471 |
COMPOSITION FOR INHIBITION OF CATHEPSIN K
The present invention relates to the a method of inhibiting bone resorption in a mammal in need thereof with an oral pharmaceutical composition comprising a cathepsin K inhibitor, or a... |
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US20130023879 |
METHOD FOR AUGMENTING, REDUCING, AND REPAIRING BONE WITH THERMOPLASTIC MATERIALS (AS AMENDED)
A method for augmenting a tissue including introducing into the tissue a first thermoplastic material at a first condition; treating the first thermoplastic material to achieve a second condition... |
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US20100047306 |
PHARMACEUTICAL COMPOSITIONS COMPRISING BISPHOSPONATES
The present invention relates to depot formulations comprising a poorly water soluble salt of a bisphosphonate forming together with one or more biocompatible polymers. The depot formulation may... |
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US20110319364 |
FOAMING ALCOHOL COMPOSITIONS WITH SELECTED DIMETHICONE SURFACTANTS
Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear... |
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US20060210639 |
Nanoparticulate bisphosphonate compositions
Nanoparticulate bisphosphonate compositions, having an effective average particle size of less than 2000 nm, are described. The compositions are useful in treating bone resorption in a mammal. |
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US20070066571 |
Novel bisphosphonates having anti-inflammatory and/or pain-killing properties
This invention describes new and novel bisphosphonate conjugates having anti-inflammatory and/or pain-killing properties. |
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US20050063902 |
Stabiliser for radiopharmaceuticals
The present invention provides an improved stabiliser for radiopharmaceuticals which inhibits impurities from being produced by two kinds of decomposition mechanisms and exhibits such an effect... |
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US20120135930 |
METHODS OF CORRECTING IMBALANCE BETWEEN BONE RESORPTION AND BONE FORMATION AND KITS AND COMPOSITIONS THEREFOR
Compounds, methods, uses, compositions, kits and packages for the treatment of imbalance between bone resorption and bone formation, based on uses of 4-phenyl-2-propionamidotetralin (4-P-PDOT) and... |
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US20050113343 |
Solid-state form of alendronate sodium and preparation thereof
A new solid-state form of alendronate sodium and process for its preparation are provided. The disclosure is also directed to pharmaceutical compositions containing the solid-state form, and to... |
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US20080182822 |
Liquid Pharmaceutical Compositions Comprising a Bisphosphonate Compound
The present invention relates to liquid pharmaceutical compositions comprising a bisphosphonate compound. |
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US20050037089 |
Method for promoting bone growth
A method for treating a patient to promote bone growth, comprising: administering to the patient a therapeutic amount of a bone remodeling agent effective to stimulate bone growth, and a dietary... |
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US20070225258 |
COMPOSITIONS COMPRISING BISPHOSPHONATE AND AN ANTIFOLATE
Compositions and methods for the treatment of arthritis, particularly rheumatoid arthritis and osteoarthritis. These compositions include at least one antifolate and at least one bisphosphonate,... |
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US20060241086 |
Calcium salt of myo-inositol 1,6:2,3:4,5 tripyrophosphate as an allosteric effector of hemoglobin
The present invention relates to various salts of inositol tripyrophosphate including the calcium, lithium, beryllium, magnesium, potassium, strontium, barium, rubidium and cesium salts of... |