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US20130252843 METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS  
Disclosed embodiments concern differentiating and classifying one or more targets using a perhalophenylazide-derived nanoparticle probe, or multiple such probes. Particular embodiments concern...
US20120122711 SCREENING OF BIOPOLYMERS  
Described herein are inventive compositions and methods relating to sampling of biopolymers and, in particular, to fractional sampling of biopolymers. In one aspect, embodiments are generally...
US20140213483 LABELED DEVICE  
A microarray is disclosed comprising a reaction zone and a labeling zone, wherein the at least one labeling zone contains a marker, such as an alphanumerical code, a binary code, a barcode, a 2D...
US20150141296 METHODS FOR PERFORMING PATTERNED CHEMISTRY  
Provided are methods for performing patterned chemistry and arrays prepared thereby.
US20120245057 WHOLE PROTEOME TILING MICROARRAYS  
The present invention relates to a microarray comprising at least 50,000 oligopeptide features per cm2 where the oligopeptide features represent at least 50%, 60%, 70%, 80%, 90%, 95%, 99%, or 100%...
US20140342947 Compositions and methods for entrapping protein on a surface  
The present invention provides a formulation to link protein to a solid support that comprises one or more proteins, Oligo-dT and one or more non-volatile, water-soluble protein solvents, solutes...
US20130029858 Method of Drug Screening through Quantitative Detection by Atomic Force Microscopy and Effective Protein Chips Development through Method Thereof  
A method for drug screening is provided. An atomic force microscopy (AFM) is used to obtain quantitative difference. At least one receptor is immobilized on a probe of the AFM and at least one...
US20150065389 MULTI-WELL MICROPATTERNING BY ABLATION  
The present invention is drawn to the generation of micropatterns of biomolecules and cells on standard laboratory materials through selective ablation of a physisorbed biomolecule with oxygen...
US20140235510 MICROFLUIDIC INTERFACE FOR HIGHLY PARALLEL ADDRESSING OF SENSING ARRAYS  
Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or...
US20120122737 METHODS FOR SELECTING AND AMPLIFYING POLYNUCLEOTIDES  
The invention provides methods for controlling the density of different molecular species on the surface of a solid support. A first mixture of different molecular species is attached to a solid...
US20150005202 MACROMOLECULE DELIVERY TO NANOWELLS  
Provided herein is technology relating to depositing and/or placing a macromolecule at a desired site for an assay and particularly, but not exclusively, to methods and systems for transporting a...
US20120258892 Methods, Compositions, and Kits for Making Targeted Nucleic Acid Libraries  
The present invention provides a method and a kit for selecting and enriching target sequences specific for a genomic region of interest or a subset of a transcriptome using a target-capturing...
US20130324439 Elastic Modulus-modified MicroEnvironment microArrays (eMEArrays) and Uses Thereof  
A combinatorial elastic modulus-modified microenvironment microarray (eMEArray) platform and methods for cell-based functional screening of interactions with combinatorial microenvironments. The...
US20150159204 Single Molecule Arrays for Genetic and Chemical Analysis  
Random arrays of single molecules are provided for carrying out large scale analyses, particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one aspect, arrays of the...
US20150087555 METHOD FOR IMMOBILIZING BIOLOGIC MOLECULES ON SOLID SURFACES  
The invention provides a method for immobilization of biological molecules such as nucleic acids, peptides and proteins onto the surface of a glass or plastic solid support.
US20150174547 TRANSFECTION SYSTEMS, METHODS AND MEDIA  
Systems, methods and media for transfection are provided. In an example embodiment, a method of printing layered arrays of spots onto a substrate includes printing a first array of spots onto the...
US20110152123 CELLULAR SCREENING SUBSTRATUM AND MANUFACTURING PROCESS FOR IT, AND METHOD AND APPARATUS FOR CELLULAR SCREENING WITH IT  
The present invention provides cellular screening substrata which can be formed in simple processing steps. The cellular screening substrata can be formed which are characterized in that plural...
US20150024974 MULTIANALYTE MOLECULAR ANALYSIS USING APPLICATION-SPECIFIC RANDOM PARTICLE ARRAYS  
The present invention provides a method for the generation of novel libraries of encoded magnetic particles from sub-libraries of by the generation of novel sub-libraries of magnetic nanoparticles...
US20110118150 METHOD FOR MAKING BIOCHIPS  
A method for immobilizing biological polymers such as DNA or proteins, on a solid support, by ionocovalent bond, for making biochips, and the resulting chips obtained by the method. Also, a kit...
US20150203809 CELL CULTURE  
The disclosure relates to the fabrication of a three dimensional [3-D] cell culture membrane comprising one or more functionalized surfaces adapted to provide cell culture conditions suitable for...
US20110257046 Emulsion PCR And Amplicon Capture  
Compositions and methods of use are disclosed for clonally amplifying target polynucleotide sequences in solution and attaching the amplicons to a surface by activation of a masked binding moiety.
US20080058225 Artificial receptors, building blocks, and methods  
The present invention relates to artificial receptors and arrays or microarrays of artificial receptors or candidate artificial receptors. Each member of the array includes a plurality of building...
US20100304982 SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING  
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their...
US20120040872 PREPARING CARBOHYDRATE MICROARRAYS AND CONJUGATED NANOPARTICLES  
The present invention is directed to carbohydrate microarray and conjugated nanoparticles methods of making the same.
US20140018260 ARRAYS AND METHODS FOR GUIDED CELL PATTERNING  
Guided cell patterning arrays for single cell patterning are disclosed. The arrays include a plurality of cell adhesion sites that are individually isolated on an inert surface. Each cell adhesion...
US20150038373 DE NOVO SYNTHESIZED GENE LIBRARIES  
De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are...
US20120142551 Methods for Genotyping Selected Polymorphism  
Methods for genotyping polymorphisms using a locus specific primer that is complementary to a region near a selected polymorphism are described. Methods for synthesizing pools of locus specific...
US20120172259 USING POPULATIONS OF BEADS FOR THE FABRICATION OF ARRAYS ON SURFACES  
The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes...
US20140296111 Protein-Immobilizing Solid Phase, Polynucleotide-Immobilizing Solid Phase, and Nucleic Acid Recovery Method  
A protein-immobilizing solid phase is a protein-immobilizing solid phase comprising an mRNA-nucleic acid linker-protein complex, obtained by linking the mRNA and the protein encoded by that mRNA...
US20140256561 SURFACE CHEMISTRY AND DEPOSITION TECHNIQUES  
Surface chemistries for the visualization of labeled single molecules (analytes) with improved signal-to-noise properties are provided. To be observed, analyte molecules are bound to surface...
US20120245049 System and Method for Pixelated Fluid Assay  
A method of performing a fluid-material assay employing a device including at least one active pixel having a sensor with an assay site functionalized for selected fluid-assay material. The method...
US20140274771 METHODS FOR MAKING MICROARRAYS AND THEIR USES  
The present invention provides microarrays that can be analysed by more than one technique using a non-covalent ligand attachment strategy to solid supports such as indium tin oxide (ITO) covered...
US20130267433 Carbohydrate Chip for Detection of Pathogen Vibrio Cholerae and Method of Preparing the Same  
The present invention related to a saccharide-based cholera toxin detection sensor for detection of Vibrio cholerae and its use. More specifically, the present invention relates to a carbohydrate...
US20130096034 MICROFABRICATION METHODS FOR THE OPTIMAL PATTERNING OF SUBSTRATES  
A method of fabricating a microarray including the steps of: (a) contacting a substrate having wells with a reagent reactive with said substrate to produce a surface modification within said wells...
US20140308303 METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND  
The disclosure relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two...
US20150141269 HYBRIDIZATION-BASED REPLICATION OF NUCLEIC ACID MOLECULES  
The present invention provides methods for replication of nucleic acid molecules distributed on a surface or within a layer by transferring them to a target surface covered with oligonucleotides,...
US20130190202 DEVICES AND PROCESSES FOR ANALYSING INDIVIDUAL CELLS  
A device for individually analysing cells of interest, comprising (a) a channel for receiving the contents of a cell of interest, wherein the channel has an input end and an output end, and (b) a...
US20130237430 PROTEIN OR PEPTIDE PRINTING METHOD, PROTEIN ARRAY OR PEPTIDE ARRAY AND FUNCTIONAL PROTEIN OR FUNCTIONAL PEPTIDE IDENTIFICATION METHOD  
The present invention relates to a protein or peptide printing method, comprising (a) a step for preparing nucleic acids and a cell-free protein synthesis system in an engraved plate composed of...
US20140235505 RNA ARRAY COMPOSITIONS AND METHODS  
Described herein are RNA arrays, and compositions and methods for generating RNA arrays, particularly high density RNA arrays. The disclosed methods for generating RNA arrays utilize template DNA...
US20140349891 Preparation of Templates for Nucleic Acid Sequencing  
The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise: providing at least one double-stranded nucleic acid molecule, wherein both strands...
US20050032084 Method of attaching a biopolymer to a solid support  
The present invention relates, in general, to a method of attaching a biopolymer to a solid support and, in particular, to a method of attaching a nucleic acid to a glass surface, and to reagents...
US20150065356 METHODS OF BEAD MANIPULATION AND FORMING BEAD ARRAYS  
According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash...
US20150099656 Multiplex Immuno Screening Assay  
The present invention provides kits and assay methods for the early detection of pathogens, precise identification of the etiologic agent, and improved disease surveillance. More specifically, the...
US20090081638 Immobilisation of Antigenic Carbohydrates to Support Detection of Pathogenic Microorganisms  
The invention relates to the field of chemistry and diagnosis, more in particular to diagnosis of current and/or past and/or symptomless infections or of a history of exposure to, a...
US20110130307 Microanalysis Chip Adhesive Sheet, Microanalysis Chip, And Manufacturing Method Thereof  
Disclosed is a microanalysis chip adhesive sheet with an adhesive surface, which can be inexpensively but easily bonded to a substrate at a relatively low temperature, with which fabrication of...
US20090163380 ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY  
A novel affinity capture surface, as well as methods of using and making the affinity capture surface and sample presentation devices or biochips comprising the affinity capture surface, are...
US20140287945 SURFACE OXIDATION FOR SEQUESTERING BIOMOLECULES AND RELATED METHODS  
Solid supports comprising polymers covalently bound to a solid substrate are provided. The polymers find utility in any number of applications including immobilizing analyte molecules to solid...
US20110046013 METHOD TO GENERATE BIOMOLECULAR MICRO- AND NANO-PATTERNS BY PARTICLE PRINTING LITHOGRAPHY  
Methods for preparing useful patterns of biomolecules on solid supports employ particle printing lithography techniques whereby suspensions of different bioconjugates are loaded onto portions of a...
US20140256594 DNA PHOTOLITHOGRAPHY WITH CINNAMATE CROSSLINKERS  
The present invention relates generally to cinnamate crosslinkers. Specifically, the present invention relates to gels, biochips, and functionalized surfaces useful as probes, in assays, in gels,...
US20080312100 Hybridization Method as Well as Hybridization Microarray and Hybridization Kit  
A method of simply and reliably hybridizing a sample biopolymer using a glass coverslip and a closed vessel by hybridizing the sample biopolymer and a probe biopolymer with each other in a state...

Matches 1 - 50 out of 337 1 2 3 4 5 6 7 >