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US20100298160 |
METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN ER-PATIENTS
A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41,... |
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US20130130939 |
PORTABLE PHOTONIC SENSOR SYSTEM AS AN EARLY DETECTION TOOL FOR OVARIAN CANCER
A guided mode resonance (GMR) sensor that can be used to simultaneously detect an array of analytes. It provides a diagnostic system that can rapidly detect an array of biomarker proteins in... |
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US20120088685 |
DIAGNOSIS OF NEUROPSYCHIATRIC AND BEHAVIOURAL DISORDERS
This invention provides a method of identifying GAS infection as the cause of a neuropsychiatric or behavioural disorder in a patient, or of identifying a patient at risk of developing a... |
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US20140274777 |
LIPID DROPLET PROTEIN MARKERS FOR ALGAL OIL ACCUMULATION
The application relates to apparatuses, methods and kits for detecting and quantifying oil content in algal samples. |
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US20120276145 |
EXTRACELLULAR MATRIX PROTEINS FROM HAEMOPHILUS INFLUENZAE BIOFILMS: TARGETS FOR THERAPEUTIC OR DIAGNOSTIC USE
A method of identifying a biofilm that includes non-typeable Haemophilus influenza (NTHi) including a step of screening a sample for the presence of one or more biofilm-specific proteins that are... |
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US20120238478 |
PROTEIN MARKERS FOR THE DIAGNOSIS AND PROGNOSIS OF OVARIAN AND BREAST CANCER
Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of... |
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US20140323347 |
POINT OF CARE IMMUNIZATION TESTING SYSTEM
A point of care immunization system based upon microfluidics and micro-titration technologies to rapidly test a patient in order to ascertain an immunization profile so that vaccinations can be... |
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US20150079116 |
DIAGNOSTIC TOOLS FOR RESPONSE TO 6-THIOPURINE THERAPY
NK cell licensing predisposes patients to chronic inflammatory disease. Methods and kits to diagnose and treat chronic inflammatory disease based on genetic haplotype and cytokine profile are... |
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US20140256579 |
Protein Arrays
Protein arrays are provided comprising single domain antibodies obtainable from Camelidae which are capable of detecting even minor changes in the expression of proteins in cell and tissue... |
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US20120046182 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of... |
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US20150110897 |
Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to... |
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US20130122027 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of... |
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US20110190149 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of... |
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US20120231969 |
PROTEIN ARRAYS AND USES THEREOF
Illustrative embodiments herein disclosed relate to protein arrays, methods for making the arrays and methods for using them, among others. In some embodiments known proteins representing at least... |
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US20140141992 |
NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of... |
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US20120028835 |
SECERNIN-1 AS A MARKER FOR CANCER
Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a... |
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US20140274787 |
BIOMARKER FOR OVARIAN CANCER CTAP3-RELATED PROTEINS
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a... |
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US20150259739 |
DETERMINING AGE RANGES OF SKIN SAMPLES
The present invention provides methods for characterizing a skin sample of a subject as belonging to an age range by analyzing nucleic acid or protein molecules obtained from the subject. The... |
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US20120214710 |
METHOD OF PREDICTING RESPONSE TO THALIDOMIDE IN MULTIPLE MYELOMA PATIENTS
A method of predicting response to thalidomide, or thalidomide analogs, in an individual with cancer, especially cancers for which thalidomide has been implicated as a treatment, such as Multiple... |
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US20130058863 |
4-Protein Biomarker Panel for the Diagnosis of Lymphoma from Biospecimen
A panel of lymphoma related biomarkers are provided. The panel allows the identification of a subject at risk for a lymphoma. Further provided are methods of optimizing therapeutic efficacy... |
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US20110257042 |
Debulking Catheters And Methods
A debulking catheter comprising a tissue debulking assembly for removing a continuous strand of material from a body lumen. Catheters of the present invention generally include a catheter body... |
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US20120178640 |
Nanotube Array for Optical Detection of Protein-Protein Interactions
A composition can include a nanostructure, and a linker associated with the nanostructure, wherein the linker is configured to interact with a capture protein. The nanostructure can include a... |
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US20150018251 |
PROTEIN CHIPS, PREPARATION AND USE THEREOF
The present invention relates to the field of medicine, in particular of research and diagnosis. It relates more particularly to a novel tool for detecting antibodies in a biological sample... |
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US20130178388 |
Methods and Kits for the Diagnosis of Rheumatoid Arthritis
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins... |
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US20110065609 |
Methods and Kits for the Diagnosis of Rheumatoid Arthritis
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins... |
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US20150119266 |
ANTIBODY ARRAY USED FOR THE ANALYSIS OF THE THREE-DIMENSIONAL STRUCTURE OF PROTEIN THERAPEUTICS AND ITS PRODUCTION
This invention relates to an antibody array for the analysis of the three-dimensional structure of a protein. It includes the development and production of the antibody array and methods of using... |
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US20130090256 |
BIOMARKERS FOR EARLY DETECTION OF OVARIAN CANCER
Biomarker proteins that can be used in the diagnosis of early-stage ovarian cancer (OC) are described. The biomarker panels not only permit the distinction of patients with ovarian neoplasia... |
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US20110306507 |
METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN HER2+PARTIENTS
A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, and possibly 40, 45, 50,... |
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US20140221621 |
SINGLE-CHAIN MULTIVALENT BINDING PROTEIN COMPOSITIONS AND METHODS
Provided are protein, nucleic acid, and cellular libraries of single chain multivalent binding proteins (e.g., scDVD and scDVDFab molecules) and methods of using these of these libraries for the... |
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US20130079249 |
GLYCOSYLATION ASSAY, GLYCOANALYSIS ARRAY AND AN ASSAY SYSTEM
An improved glycosylation assay, glycoanalysis array and an assay system for performing glycosylation assays glycoanalysis array. |
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US20120289429 |
BIOCHIP COMPRISING MULTIPLE MICROCHANNELS
A biochip includes a plurality of microchannels; and a plurality of probes disposed in an inner wall of each of the plurality of microchannels forming a one-dimensional array. The one-dimensional... |
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US20130274124 |
ADHESION SIGNATURES
The present invention provides arrays comprising polypeptides associated with extracellular matrix that can be used to isolate, differentiate, or culture certain cell types including stem cells,... |
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US20110136692 |
PROTEIN MICROARRAYS FOR MASS SPECTROMETRY AND METHODS OF USE THEREFOR
The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays... |
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US20110257035 |
IDENTIFICATION OF SIGNATURE GENES ASSOCIATED WITH HEPATOCELLULAR CARCINOMA
The present invention relates to, for example, (1) a novel method for identification of clinically useful serum and/or tumor biomarkers and expression signatures that can be used for detection,... |
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US20150160226 |
METHOD, REAGENTS, AND KITS FOR DETECTING MINIMAL RESIDUAL DISEASE
The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological... |
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US20110301057 |
IN SITU ORIENTED IMMOBILIZATION OF PROTEINS ON A SUPPORT
The present invention relates to a method of directing in situ oriented immobilization of a protein on a support. This method involves providing a support and contacting the support with a... |
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US20130203609 |
LIBRARY-BASED METHODS AND COMPOSITIONS FOR INTRODUCING MOLECULAR SWITCH FUNCTIONALITY INTO PROTEIN AFFINITY REAGENTS
Methods and compositions are disclosed for introducing molecular switch functionality into a protein affinity reagent to render its binding to a target molecule sensitive to an environmental... |
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US20140235476 |
MULTIVALENT BINDING PROTEIN COMPOSITIONS AND METHODS FOR IDENTIFYING VARIANTS OF SAME
Provided are protein, nucleic acid, and cellular libraries of multivalent binding proteins (e.g., DVD-Fab or DVD-Ig molecules) and the use of these libraries for the screening of multivalent... |
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US20120184560 |
MOLECULAR DIAGNOSTIC METHODS FOR PREDICTING BRAIN METASTASIS OF BREAST CANCER
Disclosed are molecular diagnostic compositions and methods for predicting brain metastasis of breast cancer, as well as methods for drug repositioning to identify existing and new therapeutics... |
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US20140038899 |
BIOMARKERS FOR OVARIAN CANCER
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention... |
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US20150240309 |
Methods and Tools for Vel Blood Group Typing
The present invention relates to methods and tools for discriminating between Vel negative and Vel positive phenotypes. The invention is thus useful for determining Vel blood group status of... |
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US20140194305 |
INTEGRATED MULTIPLEX TARGET ANALYSIS
This invention provides biochip cartridges and instrument devices for the detection and/or analysis of target analytes from patient samples. |
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US20140106981 |
Organ-Specific Proteins and Methods of Their Use
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific... |
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US20120087862 |
ORGAN-SPECIFIC PROTEINS AND METHODS OF THEIR USE
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific... |
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US20110190168 |
APOPTOSIS MODULATOR BCL-B AND METHODS FOR MAKING AND USING SAME
A novel human member of the Bcl-2 family Bcl-B has been identified, which is Closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is Widely expressed in adult human... |
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US20130045873 |
METHODS FOR IDENTIFYING AND USING ORGAN-SPECIFIC PROTEINS IN BLOOD
The present invention relates generally to methods for identifying organ-specific secreted proteins and for identifying organ-specific molecular blood fingerprints therefrom. As such, the present... |
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US20150204890 |
MICROARRAYS OF G PROTEIN COUPLED RECEPTORS
Microarrays encompassing GPCRs, methods of making such microarrays, and methods of using such microarrays are described. |
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US20120157335 |
Flap Endonuclease-1 As A Marker For Cancer
Methods aiding in the assessment of cancer comprising use of the Flap endonuclease-1 protein (=FEN1) as a universal marker of different cancer types are provided. In particular, methods for... |
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US20140221232 |
COMPUTER-IMPLEMENTED SYSTEM AND METHOD FOR THE PREDICTION OF CANCER RESPONSE TO GENOTOXIC CHEMOTHERAPY AND PERSONALISED NEOADJUVANT TREATMENTS (PCCP)
A method for predicting an individual's response to a treatment for cancer, the method comprising a step of assaying a biological sample from the individual to determine the abundance of a panel... |
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US20140274778 |
METHODS AND SYSTEMS FOR MULTIPLEX ASSAYS
Disclosed herein are compositions comprising beads with unique identifiers for storing information about a multiplex assay as well as methods for using the same in multiplex chemical and... |