|
Match
|
Document |
Document Title |
|
|
US20120264627 |
Oligonucleotide Array For Tissue Typing
Oligonucleotide-based microarrays for tissue typing (e.g., HLA tissue typing) are provided. More particularly, the microarrays are high resolution arrays useful for diagnostic evaluations and... |
|
|
US20140274777 |
LIPID DROPLET PROTEIN MARKERS FOR ALGAL OIL ACCUMULATION
The application relates to apparatuses, methods and kits for detecting and quantifying oil content in algal samples. |
|
|
US20150079116 |
DIAGNOSTIC TOOLS FOR RESPONSE TO 6-THIOPURINE THERAPY
NK cell licensing predisposes patients to chronic inflammatory disease. Methods and kits to diagnose and treat chronic inflammatory disease based on genetic haplotype and cytokine profile are... |
|
|
US20110034347 |
Signatures Associated with Rejection or Recurrence of Cancer
Methods and tools for assessing the prognosis for patients following treatment of primary tumors are provided. The methods involve identifying immune-related genetic markers whose differential... |
|
|
US20120094292 |
FORENSIC IDENTIFICATION
The invention provides allelic ladder mixtures and individual alleles suitable for use in such mixtures. The allelic ladder mixtures give improved identification and distinguishing capabilities,... |
|
|
US20120015832 |
METHODS, PANELS OF IDENTIFICATION MARKERS, AND KITS FOR IDENTIFYING FORENSIC SAMPLES
Methods for identifying forensic samples using panels of markers and gene expression profiling, including without limitation, mRNA profiling, miRNA profiling, or both, are disclosed. Panels of... |
|
|
US20150110897 |
Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to... |
|
|
US20120264720 |
IDENTIFICATION AND TREATMENT OF CANCER SUBSETS
Methods of predicting whether or not a tumor will be responsive to IP6 treatment, methods of treating patients with cancer using IP6, methods of predicting the progression of a disease, and kits... |
|
|
US20120225791 |
ARRAY-BASED METHOD FOR DETECTION OF COPY NUMBER VARIATIONS IN THE HLA LOCUS FOR THE GENETIC DETERMINATION OF SUSCEPTIBILITY OF DEVELOPMENT OF VENOUS MALFORMATIONS IN THE EXTRACRANIAL SEGMENTS OF THE CEREBROSPINAL VEINS AND KIT THEREOF
Method for in vitro diagnosis of susceptiblility of developing venous malformations i the extracranial segment of the cerebrospinal veins in a patient comprising the detection of copy number... |
|
|
US20150259739 |
DETERMINING AGE RANGES OF SKIN SAMPLES
The present invention provides methods for characterizing a skin sample of a subject as belonging to an age range by analyzing nucleic acid or protein molecules obtained from the subject. The... |
|
|
US20110301054 |
Method of Stratifying Breast Cancer Patients Based on Gene Expression
The present invention assists in prospectively predicting the metastatic likelihood, and thereby, the likely clinical outcome of breast cancer patients, based on the genotype of the patient, in... |
|
|
US20120065084 |
METHODS AND TOOLS FOR PREDICTING THE EFFICIENCY OF ANTHRACYCLINES IN CANCER
A gene set, kit and method predict the efficiency of anthracyclines-based treatment of breast cancer. |
|
|
US20110177957 |
Polymorphisms Associated With Age-Related Macular Degeneration And Methods For Evaluating Patient Risk
The present invention provides for certain polynucleotide sequences that have been correlated to AMD. These polynucleotides are useful as diagnostics, and are preferably used to fabricate an... |
|
|
US20130058863 |
4-Protein Biomarker Panel for the Diagnosis of Lymphoma from Biospecimen
A panel of lymphoma related biomarkers are provided. The panel allows the identification of a subject at risk for a lymphoma. Further provided are methods of optimizing therapeutic efficacy... |
|
|
US20150045237 |
METHOD FOR IDENTIFICATION OF THE SEQUENCE OF POLY(A)+RNA THAT PHYSICALLY INTERACTS WITH PROTEIN
The invention relates to an in vitro method for identifying the sequence of one or more poly(A)+RNA molecules that physically interacts with protein. The present invention provides a method to... |
|
|
US20120185174 |
Prognostic Signature for Colorectal Cancer Recurrance
An assay system is useful for predicting recurrence and/or non-recurrence of colorectal cancer in a patient. The assay system is adapted to analyze a patient sample for quantitative expression of... |
|
|
US20140377861 |
Precise Control of Recombinant Protein Levels by Engineering Translation
Compositions and methods are provided for user-specified fine-tuned protein expression levels, by controlling the initiation of protein translation; and a model for analysis of expression. This... |
|
|
US20150018323 |
3B-HYDROXYSTEROID DEHYDROGENASE IN STEROID-DEPENDENT DISEASE
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a... |
|
|
US20140031258 |
SERUM-BASED MIRNA MICROARRAY AND ITS USE IN DIAGNOSIS AND TREATMENT OF BARRETT'S ESOPHAGUS (BE) AND ESOPHAGEAL ADENOCARCINOMA (EAC)
Robust and reliable molecular diagnostic screening tools for early detection of esophageal and gastrointestinal tract cancers and pre-cancerous lesions, such as Barrett's Esophagus, and esophageal... |
|
|
US20120316080 |
DIFFERENTIATION BETWEEN BRCA2-ASSOCIATED TUMOURS AND SPORADIC TUMOURS VIA ARRAY COMPARATIVE GENOMIC HYBRIDIZATION
Array comparative genomic hybridization classifiers, arrays comprising the classifiers and methods of using the same for differentiating between BRCA2-associated tumors and sporadic tumors by... |
|
|
US20120178640 |
Nanotube Array for Optical Detection of Protein-Protein Interactions
A composition can include a nanostructure, and a linker associated with the nanostructure, wherein the linker is configured to interact with a capture protein. The nanostructure can include a... |
|
|
US20110143962 |
METHOD OF EVALUATING ORAL CANCER RISK IN HUMAN
A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus,... |
|
|
US20140274773 |
SYSTEMS AND METHODS FOR EMPLOYING PODOCALYXIN AND TRA HUMAN STEM CELL MARKERS AS PROGNOSTIC MARKERS FOR AGGRESSIVE AND METASTATIC CANCER
The invention relates to systems and methods to detect podocalyxin-expressing and TRA-expressing cancer stem cells or cancer cells with stem cell-like properties in a tissue cell sample obtained... |
|
|
US20130090256 |
BIOMARKERS FOR EARLY DETECTION OF OVARIAN CANCER
Biomarker proteins that can be used in the diagnosis of early-stage ovarian cancer (OC) are described. The biomarker panels not only permit the distinction of patients with ovarian neoplasia... |
|
|
US20130096022 |
Methods and Materials Related to Ovarian Cancer
Described herein are methods for diagnosing ovarian cancer. In particular, certain microRNAs are useful to the response to chemotherapy of ovarian cancer patients. |
|
|
US20140235458 |
METHODS AND TOOLS FOR THE DIAGNOSIS AND PROGNOSIS OF UROGENITAL CANCERS
The present invention provides a microarray useful as a tool in the diagnosis and/or prognosis of certain types of cancers, particularly urogenital cancers. The microarray can include a plurality... |
|
|
US20140017227 |
GENE SIGNATURES FOR USE WITH HEPATOCELLULAR CARCINOMA
The present invention provides a method for predicting prognosis of hepatocellular carcinoma patients based on measurement of the relative level of expression of a combination of 15 immune genes... |
|
|
US20150197816 |
METHODS FOR THE DETECTION, VISUALIZATION AND HIGH RESOLUTION PHYSICAL MAPPING OF GENOMIC REARRANGEMENTS IN BREAST AND OVARIAN CANCER GENES AND LOCI BRCA1 AND BRCA2 USING GENOMIC MORSE CODE IN CONJUNCTION WITH MOLECULAR COMBING
Methods for detecting genomic rearrangements in BRCA1 and BRCA2 genes at high resolution using Molecular Combing and for determining a predisposition to a disease or disorder associated with these... |
|
|
US20130324438 |
METAGENE EXPRESSION SIGNATURE FOR PROGNOSIS OF BREAST CANCER PATIENTS
Described are gene expression signatures able to distinguish individuals having or suspected to have breast cancer with good clinical prognosis from individuals with poor clinical prognosis, based... |
|
|
US20140378334 |
METHOD FOR QUANTIFYING RENAL MARKERS BY ASSAYING URINE
The invention pertains to a method of in vitro diagnosis of pathologies in a patient. According to the invention, the method comprises the following steps: a) obtaining a urine sample from said... |
|
|
US20140221242 |
GENOME-WIDE METHYLATION ANALYSIS AND USE TO IDENTIFY GENES SPECIFIC TO BREAST CANCER HORMONE RECEPTOR STATUS AND RISK OF RECURRANCE
To better understand the biology of hormone receptor-positive and negative breast cancer and to identify methylated gene markers of disease progression, a genome-wide methylation array analysis... |
|
|
US20140342925 |
METHOD FOR PREDICTING A MANIFESTATION OF AN OUTCOME MEASURE OF A CANCER PATIENT
The invention pertains to a method for predicting a manifestation of an outcome measure of a cancer patient based on a tumor DNA containing tissue sample from the cancer patient, comprising,... |
|
|
US20120289429 |
BIOCHIP COMPRISING MULTIPLE MICROCHANNELS
A biochip includes a plurality of microchannels; and a plurality of probes disposed in an inner wall of each of the plurality of microchannels forming a one-dimensional array. The one-dimensional... |
|
|
US20120184454 |
GENE SIGNATURE IS ASSOCIATED WITH EARLY STAGE RECTAL CANCER RECURRENCE
Applicants have identified a 36-gene signature that is associated with recurrence of stage I and II rectal cancers not treated with chemotherapy or radiation. This signature can be used to... |
|
|
US20130065786 |
METHOD FOR BREAST CANCER RECURRENCE PREDICTION UNDER ENDOCRINE TREATMENT
The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient... |
|
|
US20120021935 |
SIGNATURE FOR THE DIAGNOSIS OF CANCER AGGRESSIVENESS AND GENETIC INSTABILITY
The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a cancer in a patient from a cancer sample of said patient, comprising: a) measuring in vitro... |
|
|
US20110257035 |
IDENTIFICATION OF SIGNATURE GENES ASSOCIATED WITH HEPATOCELLULAR CARCINOMA
The present invention relates to, for example, (1) a novel method for identification of clinically useful serum and/or tumor biomarkers and expression signatures that can be used for detection,... |
|
|
US20130102483 |
METHODS FOR THE ANALYSIS OF BREAST CANCER DISORDERS
The present invention relates to methods, arrays and computer programs for assisting in classifying breast cancer diseases. In particular the invention relates to classifying breast cancer... |
|
|
US20110166107 |
METHODS AND KITS FOR DETECTING RISK FACTORS FOR DEVELOPMENT OF JAW OSTEONECROSIS AND METHODS OF TREATMENT THEREOF
Methods of and kits for determining the pharmacogenetic, pharmacokinetic and cellular basis of bisphosphonate-induced osteonecrosis of the jaw (BONJ) involve associating particular proteins and... |
|
|
US20130267432 |
IN VITRO DIAGNOSTIC METHOD FOR PATIENTS WITH SPLENIC MARGINAL ZONE LYMPHOMA
The present invention refers to an in vitro SMZL diagnostic method based on analysis of the expression of a series of genes located in a very specific deleted region of human chromosome 7. The... |
|
|
US20110152352 |
SMAD PROTEINS CONTROL DROSHA-MEDIATED MIRNA MATURATION
The invention, in some aspects, relates to compositions and methods useful for modulating expression of miRNAs that are regulated by the TGF-β/BMP signaling pathway. In some aspects, the invention... |
|
|
US20110136679 |
Imprinted Array
There is described a gene expression array comprising more than one imprinted gene and one or more control genes for the diagnosis of human epigenetic diseases resulting from assisted reproduction... |
|
|
US20150258170 |
Diagnosis and Treatment of SMA and SMN Deficiency
The present invention provides for methods for diagnosing and treating a motor neuron disease. More specifically, the present invention offers new methods for diagnosing and treating SMA or SMN... |
|
|
US20140274780 |
METHODS OF IMPROVING SURVIVAL IN CANCER
Methods of improving cancer therapy outcomes are provided. Diagnostics useful for evaluating patients based on microRNA signatures of cancer tissue are provided. |
|
|
US20120237488 |
LSC AND HSC SIGNATURES FOR PREDICTING SURVIVAL OF PATIENTS HAVING HEMATOLOGICAL CANCER
A method for determining prognosis in a subject having a hematological cancer comprising: a) determining an expression profile by measuring the gene expression levels of a set of genes selected... |
|
|
US20120041274 |
CANCER BIOMARKERS
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided. |
|
|
US20130065775 |
Methods for diagnosing skin diseases
The present invention relates to methods for diagnosing cornification disorders and metabolic diseases. More specifically, the present invention relates to an in vitro method for diagnosing and/or... |
|
|
US20150094221 |
Method for Indicating the Presence or Non-Presence of Prostate Cancer
The present invention relates generally to the detection and identification of various forms of genetic markers, and various forms of proteins, which have the potential utility as diagnostic... |
|
|
US20150141391 |
SYSTEMS AND METHODS FOR DETERMINING A TREATMENT COURSE OF ACTION
The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to mutations in the gene encoding estrogen receptor and their... |
|
|
US20110177096 |
USE OF GPR151 MODULATORS FOR THE TREATMENT OF PAIN
The present invention relates to nucleic acid arrays used to detect genes which are up or down regulated following a pain stimulus in a mammal. It further relates to the use of GPR151 in methods... |