Matches 1 - 50 out of 79 1 2 >


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US20170119854 HIGHLY CONCENTRATED DRUG PARTICLES, FORMULATIONS, SUSPENSIONS AND USES THEREOF  
Highly concentrated drug particle formulations are described, wherein the drug comprises between about 25 wt % and 80 wt % of the particle formulation. The particle formulations of the present...
US20100075342 Biomarker for ovarian cancer CTAP3-related proteins  
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a...
US20110065136 Methods and Devices for Detecting Glomerulonephritis and Associated Disorders  
Methods and devices for diagnosing, monitoring, or determining glomerulonephritis or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing,...
US20160341667 RAMAN SPECTROSCOPY FOR BIOPROCESS OPERATIONS  
A method of characterizing a multi-component mixture for use in a bioprocess operation that includes providing a multi-component mixture standard with pre-determined amounts of known components;...
US20070249014 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS  
Provided in certain embodiments are new methods for forming azido modified biomolecule conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided...
US20140093493 METHOD AND FORMULATION FOR REDUCING AGGREGATION OF A MACROMOLECULE UNDER PHYSIOLOGICAL CONDITIONS  
The invention provides a method for reducing aggregation and inhibiting flocculation of a macromolecule, such as a protein, under physiological conditions, by the addition of certain cyclodextrins...
US20140107181 METHODS AND MEANS FOR TREATMENT OF OSTEOARTHRITIS  
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing...
US20160202274 CLINICAL DIAGNOSIS OF HEPATIC FIBROSIS USING A NOVEL PANEL OF LOW ABUNDANT HUMAN PLASMA PROTEIN BIOMARKERS  
The inventors have proposed a novel panel of human plasma protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver...
US20160109437 Biomarker panel for dose assessment of radiation injury and micro plasma filter  
Materials, systems and methods are provided for qualitative assessment of exposure of a person to ionizing radiation by measuring amounts of the biomarkers, wherein a change compared with...
US20150056190 DIAGNOSTIC METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER  
The invention provides methods and compositions to detect expression of one or more biomarkers for identifying and treating patients who are likely to be responsive to VEGF antagonist therapy. The...
US20120288852 Force Mediated Assays  
A sensitive and specific method of detecting chemical species, viruses and microorganisms is presented to improve performance of molecular-recognition-based assays utilizing particles decorated...
US20100285491 USE OF IGFBP-7 IN THE ASSESSMENT OF HEART FAILURE  
The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker IGFBP-7, of optionally measuring in the sample...
US20070004045 Analysis of large numbers of estrogens and other steroids and applications thereof  
Mass-spectrometry based methods of analyzing estrogens and other steroids from biological samples are disclosed herein. Further disclosed are methods of detecting the presence of illegal steroids...
US20110117659 QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES  
Novel fluorescent derivitization reagents are described that are suitable for coupling to biomolecules that contain aldehyde or ketone functional groups. In one embodiment is provided reagents...
US20100280760 BIOMARKERS FOR MONITORING TREATMENT OF NEUROPSYCHIATRIC DISEASES  
Methods for identifying and measuring pharmacodynamic biomarkers of neuropsychiatric disease, and for monitoring a subject's response to treatment. For example, materials and methods for...
US20100267069 ANALYSIS OF PROTEINS FROM BIOLOGICAL FLUIDS USING MASS SPECTROMETRIC IMMUNOASSAY  
Presented herein are methods, devices and kits for the mass spectrometric immunoassay (MSIA) of proteins present in complex biological fluids or extracts. Pipettor tips containing porous solid...
US20150219674 AUTISM-ASSOCIATED BIOMARKERS AND USES THEREOF  
The invention discloses biomarkers for human autism. The invention provides methods for treating, preventing, and diagnosing human autism and autism-related disorders.
US20150093760 CARTRIDGE AND SYSTEM FOR DETECTING OF GLYCATED PROTEIN IN SAMPLE AND METHOD OF DETECTING GLYCATED PROTEIN USING THE SAME  
A cartridge for measuring a concentration of a glycated protein in a wide measurement range, a system for measuring a glycated protein, and a method of measuring a glycated protein using same.
US20130004940 Device for Detecting Analyte in Sample  
A device for detecting an analyte in a sample is provided, which comprises: a collecting chamber containing an opening for collecting a liquid sample; a detecting element for detecting an analyte...
US20160139156 APPARATUSES, METHODS, AND SYSTEMS FOR HOME MONITORING OF PHYSIOLOGICAL STATES AND CONDITIONS  
Methods, systems and apparatuses for monitoring a physiological condition of a user. The apparatus includes a housing, a processor, a power source, a receptacle configured to receive an inserted...
US20160108125 FORMULATIONS WITH REDUCED OXIDATION  
The invention provides formulations comprising a protein in combination with a compound that prevents oxidation of the protein. The invention also provides methods for making such formulations and...
US20140127735 CHARACTERIZATION OF N-GLYCAN MIXTURES BY NUCLEAR MAGNETIC RESONANCE  
The present disclosure provides nuclear magnetic resonance (NMR) methods for characterizing mixtures of N-linked glycans. Without limitation, methods of the present disclosure may be useful in...
US20090191228 Immunogenic compositions capable of activating T-cells  
Provided is means and methods for producing and/or selecting immunogenic compositions capable of activating a T-cell and/or a T-cell response, comprising providing the composition with at least...
US20080085507 SYSTEM FOR RAPID ANALYSIS OF GLYCATED PROTEINACEOUS SPECIES IN BIOLOGICAL SAMPLES  
A device is described which provides an automated or manual means to perform chromatographic affinity-based A1c analyses of whole blood or hemolysates in less than 1 minute. Further, such...
US20090075266 MULTIPLE ANALYTE DIAGNOSTIC READOUT  
The invention provides methods for assessing clinical status through the creation of a diagnostic readout based upon the analysis of multiple biomarkers. According to the invention, an algorithm...
US20080182282 Methods for comparitive analysis of carbohydrate polymers and carbohydrate polymers identified using same  
Disclosed is a method for characterizing a carbohydrate polymer by identifying at least two binding agents that bind to the carbohydrate polymer. Binding is preferably determined by contacting the...
US20080113444 Method for detecting oligermization of soluble amyloid beta oligomers  
The present invention relates to the assay, analysis, and characterization of soluble amyloid beta oligomers, as well as the characterization of inhibitors of soluble amyloid beta oligomer...
US20160161509 METHODS FOR PREDICTING EMBRYO VIABILITY  
The present invention provides methods for predicting the viability of an embryo or for predicting the likelihood of a negative outcome during pregnancy by identifying the presence or absence of...
US20130344524 ANALYSIS METHOD  
In a method for detecting a glucagon-secretin family peptide in a sample, the sample is contacted with a cleaving agent capable of digesting the glucagon-secretin family peptide by cleaving a...
US20100040637 Methods and Composition for Treating Diseases Targeting Prominin-1 (CD133)  
Methods and compositions for detecting and treating diseases, especially cancer, and particularly breast, bladder, colon, gastrointestinal, kidney, liver, lung, melanoma, ovary, pancreatic,...
US20070253946 Axon Regeneration Promoter  
An axon regeneration promoter is disclosed that contains an inhibitor of RGM-like protein as an effective component. Inhibitors of RGM-like protein encompass inhibitors of RGM-like protein such as...
US20150099306 TEST CASSETTE READING DEVICE AND READING METHOD THEREOF  
A reading device for reading and analyzing a test cassette having an identification code includes a reading unit, used for reading the identification code marked by the test cassette and carrying...
US20080044843 BIOMARKERS FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE  
Detection of expression of biomarkers (e.g., protein analytes) whose regulation is perturbed in COPD patients can be used to diagnose COPD, to confirm a diagnosis of COPD, and to assess or...
US20150099669 MASS SPECTROMETRY IMAGING OF GLYCANS FROM TISSUE SECTIONS AND IMPROVED ANALYTE DETECTION METHODS  
The presently disclosed subject matter provides methods using mass spectrometry for direct profiling of N-linked glycans from a biological sample. In addition, the embodiments of the present...
US20090311707 O-GLYCANS AS DIAGNOSTIC MARKERS FOR INFLAMMATORY BOWEL DISEASE  
The present invention provides diagnostic methods for inflammatory bowel disorders (e.g., Crohn's disease or ulcerative colitis) comprising assessing expression, structure and/or function of...
US20110059466 SUPPORT FOR ELECTROPHORESIS INCLUDING HYDROPHOBIC POLYMER MEMBRANE, AND ELECTROPHORETIC SEPARATION METHOD USING THE SAME  
There is provided a membrane electrophoresis which renders possible glycan analysis of polysaccharide and glycoprotein by separating protein, glycoprotein or polysaccharide by electrophoresis,...
US20130344511 USE OF HEMATOPOIETIC GROWTH FACTOR INDUCIBLE NEUROKININ-1 (HGFIN) AS A NOVEL BIOMARKER  
The invention provides, in certain embodiments, a method of detecting an indicator of renal injury or renal disease. The method entails assaying a urine sample for hematopoietic growth factor...
US20100129934 Glycated Insulin as a Biomarker for Diagnosis and Monitoring of Diabetes  
One of the major pathophysiological consequences of long term elevation of plasma glucose in diabetes is an increase in the non-enzymatic glycation of proteins. Contrary to expectations the...
US20100267062 Osteopontin as Novel Prognostic Biomarker for Heart Failure  
The present invention relates to methods for providing a diagnosis, prognosis and/or risk stratification of a subject with heart failure, comprising determining the concentration of osteopontin...
US20140024124 LABELING AGENT FOR ANALYZING POST-TRANSLATIONAL MODIFICATIONS OF SERINE AND THREONINE  
A glycoprotein and/or a glycopeptide which are a test substance is heated in the presence of a pyrazolone derivative, an isoxazolone derivative, a hydantoin derivative, a rhodanine derivative, a...
US20110136137 SERUM PROTEOMIC FOR FINDING DIAGNOSTIC MARKERS AND FOR MONITORING THERAPEUTICAL INTERVENTION IN TREATMENT OF HEPATOCELLULAR CARCINOMA  
The invention is directed to biomarkers for determining the EGFR kinase activity in a subject, and the use thereof for predicting and monitoring therapeutic intervention in cancer patients. Areas...
US20100279306 ANALYSIS OF PHOSPHORYLATED GLYCANS, GLYCOPEPTIDES OR GLYCOPROTEINS BY IMAC  
The present disclosure provides technologies for enriching, detecting, and/or quantifying phosphorylated glycans and/or glycoconjugates (e.g., glycopeptides, glycolipids, proteoglycans, etc.)....
US20070280930 Cd44-Targeting for Reducing/Preventing Ischemia-Reperfusion-Injury  
The present invention relates to CD44 binding molecules, preferably anti-CD44 antibodies, and their use in methods for the prevention or reduction of ischemia-reperfusion injury in e.g. solid...
US20110136160 ANALYSIS OF GLYCATED PROTEINS  
This invention relates to a method for analysis of one or more glycated proteins in a sample, the glycated proteins containing moieties of a natural reducing carbohydrate bound at one or more...
US20150005192 BIOMARKERS  
The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder.
US20160146755 DEVICES, SYSTEMS, AND METHODS FOR ELECTROPHORESIS  
Disclosed herein are devices that can be used to perform electrophoretic separations as well as methods of using thereof. The devices and methods described herein are inexpensive, user friendly,...
US20140356968 METHODS FOR COMPARING A STRUCTURE OF A FIRST BIOMOLECULE AND A SECOND BIOMOLECULE  
The present disclosure provides methods to assess structural similarity of a first biomolecule and a second biomolecule by detecting one or more responses of the first and second biomolecule to...
US20080020475 METHODS AND KITS FOR THE DIAGNOSIS OF HYPOTHYROIDISM  
Provided are methods for the detection and diagnosis of Hypothyroidism. The methods are based on the discovery that altered levels of selected analytes in sample fluid, typically blood samples, of...
US20140235473 Diagnosis and/or Prognosis of Parkinson's Disease Dementia  
The present Invention provides a method for diagnosing and/or prognosing Parkinson's disease dementia (PDD) comprising the step of detecting O-glycosylation. in a protein comprising a Ser/Thr...
US20160058850 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASES OF INFECTIOUS AND NON-INFECTIOUS ORIGIN  
The present invention is based, in part, on our analysis of C1-INH levels in various patient populations. Accordingly, in a first aspect, the invention features methods for assessing the...

Matches 1 - 50 out of 79 1 2 >