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US20150099726 DRY POWDER INHALER  
This invention provides a dry powder inhaler comprising: a dry powder medicament comprising fluticasone propionate, salmeterol xinafoate and a lactose carrier; wherein, the delivered dose of...
US20100168006 IN-PLANT PRODUCTION OF DIMERIC AND/OR OLIGOMERIC (COMPRISING THREE OR MORE UNITS) FORMS OF HUMAN APO A-1 PROTEIN MUTEINS  
The present invention encompasses a method for the production of Apolipoproteins in dimeric and/or oligomeric forms (comprising three or more units) of muteins of the human ApoA-1 protein in plant...
US20130217036 NEW DIAGNOSTIC TOOLS FOR CHARCOT-MARIE-TOOTH DISEASE  
The present invention relates in particular to methods of detecting predisposition to or diagnosis and/or prognosis of Charcot-Marie-Tooth (CMT) and related disorders. More specifically, the...
US20140364452 METHODS TO DETERMINE SUSCEPTIBILITY TO TREATMENT WITH LEUKOTRIENE MODIFIERS  
The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and...
US20120282184 TREATMENT OF OBESITY  
A method for the prevention or treatment of a condition selected from type 2 diabetes, obesity and metabolic syndrome comprising activating a GITRL pathway. Methods for screening for substances to...
US20110111511 METHODS FOR MEASURING THE METABOLISM OF NEURALLY DERIVED BIOMOLECULES IN VIVO  
The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease,...
US20150153368 Early Predictive Markers of Pre-Eclampsia  
The present invention relates to a method for measuring levels of class VI isoprostane, an early predictive marker of pre-eclampsia (PE). The present invention also relates to an assay and...
US20120238028 Means and Methods for Diagnosing Multiple Sclerosis  
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing multiple sclerosis in a subject, a method for identifying...
US20150072366 Methods for Measuring Fat Digestibility and Uses Thereof  
The present invention provides methods for continuous measurement of triglyceride digestibility during a meal. A stable isotope labeled triglyceride and a free fatty acid tracer are added to the...
US20150104877 USE OF DISULFIDE BONDS TO FORM A REVERSIBLE AND REUSABLE COATING FOR NANOFLUIDIC DEVICES  
A reusable coating for a nanopore structure is disclosed herein. A nanopore structure includes a substrate comprising a nanochannel and a monolayer of a chemical compound disposed onto at least a...
US20150031572 MEANS AND METHODS FOR ASSESSING NEURONAL TOXICITY  
The present invention pertains to the field of diagnostics for neuronal toxicity and toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method...
US20150168428 COMPOSITIONS AND METHODS FOR ASSESSING CARDIOVASCULAR DISEASE  
Some aspects of this disclosure relate to the characterization of lipoproteins (e.g., vLDL, LDL, and/or HDL) based on their content of lipoprotein-associated proteins (e.g., apolipoproteins) for...
US20110313276 NON-INVASIVE IN VITRO METHOD FOR QUANTIFYING LIVER LESIONS  
An in-vitro non-invasive method for quantifying the lesions of the liver of the patient with metabolic steatosis addressing a diagnostic target, i.e. fibrosis, steatosis and/or steato-hepatitis...
US20150011423 MEANS AND METHODS FOR ASSESSING KIDNEY TOXICITY  
The present invention pertains to the field of diagnostics for kidney toxicity and toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for...
US20100297680 METHODS FOR ASSESSING THE RISK FOR DEVELOPMENT OF CARDIOVASCULAR DISEASE  
The present invention relates to diagnostic tests, methods and kits that are useful to assess a subject's risk of developing a pathologic condition related in part to the presence of HDL oxidation...
US20150160238 Means and Methods for Diagnosing and Monitoring Heart Failure in a Subject  
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject and a method for monitoring...
US20100323374 Serum Biomarkers for Diagnosing Liver Fibrosis and Method for Measuring the Same  
Disclosed are serum biomarkers for diagnosing liver fibrosis and methods for measuring the same. The serum biomarkers obtained from human serum include alpha2-macroglobulin (“A2M”), vitamin D...
US20130157374 METHOD FOR QUANTIFYING THE AMOUNT OF CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN 3  
A method that enables quantification of cholesterol in high-density lipoprotein 3 (HDL3) in a test sample without requiring a laborious operation is disclosed. The method for quantifying...
US20150233953 KIT AND METHOD FOR QUANTITATIVE DETECTION OF STEROIDS  
The invention relates to a kit and methods for quantitative detection of steroids in a sample. The kit comprises quantitative charge tags and an oxidising agent.
US20130144114 DIAGNOSTIC METHOD FOR ENDOMETRIAL RECEPTIVITY  
The invention relates to a non-invasive diagnostic method of endometrial receptivity which includes collecting and comparing lipid biomarker patterns to reference lipidomic biomarkers,...
US20120202240 Method for Predicting the likelihood of an Onset of an Inflammation Associated Organ Failure  
The present invention relates to a reliable and statistically significant method for predicting the likelihood of an onset of an inflammation associated organ failure from a biological sample of a...
US20090318392 BIOFLUID METABOLITE PROFILING AS A TOOL FOR EARLY PREDICTION OF AUTOIMMUNITY AND TYPE 1 DIABETES RISK  
The invention concerns a method for diagnosing a child's susceptibility for developing type 1 diabetes by using a serum metabolite as biomarker. The invention concerns also a method for prevention...
US20130337445 METHOD FOR THE CLINICAL DEVELOPMENT AND MEDICAL APPLICATION OF MULTIPLEX ASSAYS DERIVED FROM PATTERNS OF INDIVIDUAL BIOMARKERS OF OXIDATIVE OR NITROSATIVE STRESS  
A method and apparatus for the discovery, development and clinical application of multiplex synthetic assays based on patterns of free radicals, indicators of oxidative or nitrosative stress, or...
US20130023054 LIPID BIOMARKERS FOR STABLE AND UNSTABLE HEART DISEASE  
The present invention relates generally to the field of diagnostic and prognostic assays for heart disease. More particular, the present invention provides an assay for diagnosing the presence or...
US20150247873 LIPIDOMIC BIOMARKERS FOR ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE  
The present invention inter alia provides a method, and use thereof, of diagnosing and/or predicting atherosclerosis or CVD by detecting the lipid concentrations or lipid ratios of a biological...
US20130045217 LIPIDOMIC BIOMARKERS FOR ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE  
The present invention inter alia provides a method, and use thereof, of diagnosing and/or predicting atherosclerosis or CVD by detecting the lipid concentrations or lipid ratios of a biological...
US20120084871 NPC1L1 ORTHOLOGUES  
The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
US20150260739 LIPOPROTEIN ANALYSIS BY DIFFERENTIAL CHARGED-PARTICLE MOBILITY  
The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle...
US20140287530 LIPOPROTEIN ANALYSIS BY DIFFERENTIAL CHARGED-PARTICLE MOBILITY  
The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle...
US20120315706 LIPOPROTEIN ANALYSIS BY DIFFERENTIAL CHARGED-PARTICLE MOBILITY  
The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle...
US20100129846 Isoform specificities of blood serum proteins and their use as differentially expressed protein biomarkers for diagnosis of breast cancer  
The present invention discloses twenty two 22 protein biomarkers of breast cancer. More specifically, the present invention discloses the identities, specificities, and uses of up to twenty two...
US20110275985 MAGNETIC NANOSENSOR COMPOSITIONS AND BIOANALYTICAL ASSAYS THEREFOR  
Disclosed are magnetic nanosensors or transducers that permit measurement of a physical parameter in an analyte via magnetic reasonance measurements, in particular of non-agglomerative assays....
US20110065208 DETERMINATION AND ESTIMATION OF ABSORPTION AND DISTRIBUTION OF SUBSTANCES IN BRAIN TISSUE  
A method determines or estimates the absorption and partition of substances into brain tissue and parameters derivable therefrom, such as the permeability of substances through the blood-brain...
US20100323451 METHOD OF PREDICTING PHOSPOLIPIDOSIS INDUCING PROPERTIES OF A SUBSTANCE  
The present invention is directed to a method for predicting the risk of a substance exhibiting phospholipidosis inducing properties, the method comprising adding the said substance to an anionic...
US20110059534 DETERMINATION OF TESTOSTERONE BY MASS SPECTROMETRY  
Provided are methods for determining the presence or amount of testosterone in a test sample, comprising ionizing all or a portion of the testosterone present in the sample to produce one or more...
US20110136241 TYPE II DIABETES MOLECULAR BIOPROFILE AND METHOD AND SYSTEM OF USING THE SAME  
Molecular bioprofiles comprising biologically correlated and relevant analytes that impact the biological state of a human health condition compared to a control population are provided. These...
US20140147875 DISEASE SEVERITY INDEX FOR ASSESSMENT OF CHRONIC LIVER DISEASE AND METHOD FOR DIAGNOSIS OF THREE DISTINCT SUBTYPES OF PRIMARY SCLEROSING CHOLANGITIS  
A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function...
US20110111392 INTEGRATED ENHANCED CHEMILUMINESCENCE BIOSENSORS  
A method and apparatus for determining the concentration of an analyte in a sample is provided. This method involves combining enhanced chemiluminescence with microchip capillary electrophoresis...
US20130203176 DETECTION METHOD  
The object of the present invention is to provide a biomarker which is highly correlated to the conventional biomarkers of metabolic syndrome or life-style related disease in a wide range of...
US20110151481 BETA-2 MICROGLOBULIN AS A BIOMARKER FOR PERIPHERAL ARTERY DISEASE  
The present invention provides β2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.
US20120028359 PRODUCTION PROCESS OF GENDER-SPECIFIC SERUM AND BIOMARKER USING THE SERUM  
The present invention relates to a production process of a gender-specific serum and a biomarker using the serum. More specifically, the present invention uses a fatty acid that exhibits a...
US20120071339 BIOMARKERS  
The invention relates to a method of diagnosing or monitoring multiple sclerosis.
US20110223675 DRUG RELEASE MEANS FROM LIPOSOMES AND METHOD FOR EVALUATING RELEASABILITY  
Drug release means from liposomes and a method for evaluating drug releasability of liposome preparations, which are useful for the quality control of a liposome preparation, are simple, accurate...
US20120322088 METHODS FOR THE DIAGNOSIS, RISK ASSESSMENT, AND MONITORING OF AUTISM SPECTRUM DISORDERS  
Methods for the diagnosis, risk assessment, and monitoring of Autism Spectrum Disorder (ASD) are disclosed. More specifically the present invention relates to the measurement of small molecules...
US20140213563 METHODS OF DIAGNOSING AND TREATING NEONATAL REVERSION TO FETAL CONSCIOUSNESS  
This invention provides methods of diagnosing and treating syndromes of reversion to fetal consciousness in a neonate.
US20100311175 MASS TAGS FOR QUANTITATIVE ANALYSES  
This invention pertains to methods, mixtures, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The...
US20120070821 Interference Control Panel for Evaluation of Analytical Assays For Samples Derived from Blood  
The invention relates to quality control of analytical assays, particularly NAT assays of blood samples containing nucleic acids. A control panel containing quantified amounts of substances known...
US20150153260 Device and method for bilirubin photoisomerization to reduce laboratory test interference  
Provided are a device and method for using bilirubin photoisomerization to reduce bilirubin interference with laboratory blood tests for other chemical analytes.
US20150105296 HYDROXY-SPHINGOMYELIN 22:1 AS A BIOMARKER FOR HEALTHY AGING  
Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort compromising centenarians, elderly and...
US20150072043 9-OXO-HODE AS A BIOMARKER FOR HEALTHY AGING  
Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort compromising centenarians, elderly and...

Matches 1 - 50 out of 325 1 2 3 4 5 6 7 >