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US20100312139 Method for Identifying Mammals at Risk for Elevated intracranial Pressure  
Disclosed are methods of diagnosing, screening and treating individuals at risk of elevated intracranial pressure based on detecting a transient decrease in serum ceruloplasmin and/or serum copper...
US20100330701 USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO  
The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present...
US20110008914 Biomarkers for the Diagnosis and Treatment of Pancreatic Cancer  
Compositions and methods which indicate an increased risk for pancreatic carcinoma are disclosed.
US20110160074 Capture Ligand Controls, Blocking Probes, Masking Probes and Methods of Using the Same  
The invention, depending on aspect and embodiment, relates to capture probe controls, and capture and signal probe configurations and combinations of configurations that can facilitate accurate...
US20150044703 METHODS AND COMPOSITIONS FOR DETECTING ENDOMETRIAL OR OVARIAN CANCER  
Some embodiments of the present invention relate to methods and compositions for detecting the presence of cancer. In particular, methods and compositions for detecting endometrial cancer or...
US20100297680 METHODS FOR ASSESSING THE RISK FOR DEVELOPMENT OF CARDIOVASCULAR DISEASE  
The present invention relates to diagnostic tests, methods and kits that are useful to assess a subject's risk of developing a pathologic condition related in part to the presence of HDL oxidation...
US20140377785 ASSEMBLY FOR SELECTIVELY PERFORMING A CLINICAL CHEMISTRY TEST OR AN ELISA ASSAY, USE OF SAID REAGENT CARTRIDGE AND ASSEMBLY  
An assembly for selectively performing a clinical chemical test or an ELISA assay including a reagent cartridge with a housing 11 having at least one cavity 12, 13, 14 that contains a reaction or...
US20110091865 MEASURING MULTIPLE ANALYTES OVER A BROAD RANGE OF CONCENTRATIONS USING OPTICAL DIFFRACTION  
The invention relates to method, devices, and kits for measuring multiple analytes in a sample having a broad range of concentrations using optical diffraction. Devices, methods, and kits useful...
US20110195526 Thermo-probes, methods of making thermo-probes, and methods of detection using thermo-probes  
Embodiments of the present disclosure provide for thermo-probes (also referred to herein as “probes”), particles including a plurality of probes, methods of making thermo-probes or particles,...
US20110151481 BETA-2 MICROGLOBULIN AS A BIOMARKER FOR PERIPHERAL ARTERY DISEASE  
The present invention provides β2 microglobulin as a biomarker for qualifying or assessing peripheral artery disease in a subject.
US20080153176 Chromatographic Test Strips for One or More Analytes  
The invention describes immunochromatographic protocols in which one or more analytes, such as a bacteria or virus, can be assayed utilizing a “sandwich” complex.
US20100297779 Biochip Self-Calibration Process  
The invention relates to a calibration process for determining the presence and/or the amount of a target compound in a test sample, using a solid support, attached to the surface of which are a...
US20110028341 METHODS, DEVICES, AND SYSTEMS FOR CHEMILUMINESCENCE-BASED MICROFLUIDIC CELL COUNTING  
A chemiluminescence-based detection system and method for counting blood cells by capturing and isolating target blood cells flowing through a microfluidic chip and detecting light emitted by the...
US20110236884 MICROBUBBLES FOR AFFINITY SEPARATION  
The present invention relates to methods, compositions and kits for affinity isolation, affinity purification and affinity assay based on microbubbles coated with an affinity molecule....
US20080102451 Companion diagnostic assays for endothelin receptor antagonists  
Methods for identifying cancer patients eligible to receive endothelin receptor antagonist therapy and for monitoring patient response to endothelin receptor antagonist therapy comprise assessment...
US20100068818 ALGORITHMS FOR MULTIVARIANT MODELS TO COMBINE A PANEL OF BIOMARKERS FOR ASSESSING THE RISK OF DEVELOPING OVARIAN CANCER  
The present invention provides methods for assessing a patient's risk of having and/or developing ovarian cancer. Also, methods for evaluating the ovarian cancer state of a patient are described...
US20110250616 ELECTROACTIVE SURFACE-CONFINABLE MOLECULES  
The invention provides compositions, kits, methods, and species that include electroactive entities which can serve as signaling entities in chemical and/or biochemical assays. The electroactive...
US20070122914 Obtaining measurements of light transmitted through an assay test strip  
Systems and methods of obtaining measurements of light transmitted through an assay test strip are described. In one aspect, a test strip is held. The top side of the test strip is illuminated...
US20110033445 CARBOHYDRATE-CONTAINING PAN CANCER MARKER  
The effective epitope of CA215, a known cancer marker and antigen, has been demonstrated to include a carbohydrate moiety of defined composition and to be non-reactive with anti-human IgG, IgA and...
US20110117670 MULTIPLEX IMMUNOASSAYS FOR HEMOGLOBIN, HEMOGLOBIN VARIANTS, AND GLYCATED FORMS  
Hemoglobin, its variants, and glycated forms of each are determined individually in a multiplex assay that permits correction of the measured level of HbA1c to account for glycated variants and...
US20090142856 Use of unique fluorochromes in rapid test systems  
The present invention includes an assay method for detecting an analyte in a sample. The assay includes a solid surface such as a nitrocellulose membrane. It also includes providing a sample is...
US20050090020 Test procedure with biological system  
Preparations containing deep-frozen blood are used for test procedures for determining blood response.
US20060240480 Use of GFAP for identification of intracerebral hemorrhage  
The present invention relates to the use of glial fibrillary acidic protein (GFAP) as a diagnostic marker for intracerebral hemorrhage. The invention especially relates to methods for the early...
US20110104825 METHOD FOR ENHANCING SENSITIVITY OR METHOD FOR AVOIDING INFLUENCE OF HEMOGLOBIN IN IMMUNOLOGICAL MEASUREMENT  
To provide a technique for enhancing measurement sensitivity or a technique for avoiding a hemoglobin influence in an immunoassay method. The invention is directed to a method for enhancing...
US20110223690 ASSAY  
The present invention provides an assay kit for detecting an analyte of interest in a sample. The kit comprises a) a reporter species; b) a labelled species having first and second binding...
US20060177944 RI-labeled compound synthesizing system  
An RI-labeled compound synthesizing system comprises an RI material synthesizing section that synthesizes a labeled precursor by using a radioisotope; a plurality of RI compound manufacturing...
US20090311804 MAGNETIC BEAD ASSISTED SAMPLE CONDITIONING SYSTEM  
A magnetic bead assisted sampling system for a fluid sensor. Magnetic beads are dispersed in a sampling volume for collecting the analyte. The beads are packed into a small volume for...
US20090104634 ONE-STEP IMMUNOASSAYS EXHIBITING INCREASED SENSITIVITY AND SPECIFICITY  
The present disclosure relates to immunoassays for detecting or quantifying at least one analyte of interest in a test sample which exhibits improved sensitivity and specificity compared to the...
US20050158812 Kits and methods for autoantibody detection  
An immunoassay method and test kit for detecting autoantibody in a patient sample, such as autoantibodies that interferes with the complexation of intrinsic factor with vitamin B12. A labeled...
US20120208299 Reduced Step Dual Path Immunoassay Device and Method  
Test cells have a first sorbent strip with a sample receiving location and defining a first migration path, a distinct second sorbent strip which receives buffer solution and at least partially...
US20100330703 ASSAYS INVOLVING COLORIMETRIC AND OTHER SIGNALING  
The present invention generally relates to particles and, in particular, to methods of determining binding involving particles, e.g., using colorimetric and other signaling techniques. In one...
US20110117675 SUBSTANCE IMMOBILIZING APPARATUS, SUBSTANCE DETECTING APPARATUS AND SUBSTANCE IMMOBILIZING METHOD  
The efficiency of the specific binding of a target substance to an immobilization region is increased. As a first step, target substance 1001 is drawn to immobilization region 1003 on which...
US20050079542 Wound monitoring  
A method of predicting or diagnosing clinical infection of a wound comprising measuring the concentration of a maker associated with an inflammatory response in wound fluid, wherein the maker is a...
US20110151584 Dual Path Immunoassay Device  
The systems of the invention include test cells with a first sorbent material defining a first flow path for a solution, a second sorbent material defining a second flow path distinct from the...
US20070111324 Alloyed semiconductor quantum dots and concentration-gradient alloyed quantum dots, series comprising the same and methods related thereto  
An alloyed semiconductor quantum dot comprising an alloy of at least two semiconductors, wherein the quantum dot has a homogeneous composition and is characterized by a band gap energy that is...
US20100330705 Immunological Test Element with Improved Control Zone  
The invention concerns a test element for carrying out an immunological sandwich test for determining an analyte from a liquid sample containing a reagent zone or conjugate zone which contains a...
US20110003401 Partial Derivatization of Particles  
There is disclosed a method for partially derivatizing a curved surface of particles in an electrically conducting solvent, said method comprises the steps: a) bringing particles in close contact...
US20100226984 MOLECULAR RECOGNITION MATRIX AND METHOD FOR MAKING SAME  
A molecular recognition matrix which utilizes the interaction between molecular building blocks and the surface of a substrate to develop specific molecular recognition cavities.
US20090280509 SURFACE ACOUSTIC WAVE IMMUNOSENSOR FOR DIAGNOSING ALLERGY DISEASE AND METHOD FOR DIAGNOSING ALLERGY DISEASE USING THE SAME  
A surface acoustic wave (SAW) immunosensor for diagnosing allergy disease includes one or more SAW devices on each of which allergens derived from one allergy-causing substance are fixed and an...
US20110229887 DETECTION OF NUCLEIC ACID AMPLIFICATION PRODUCTS IN THE PRESENCE OF AN INTERNAL CONTROL SEQUENCE ON AN IMMUNOCHROMATOGRAPHIC STRIP  
Compositions and methods useful in nucleic acid assays are provided. The invention permits detection of test and control nucleic acids. Test nucleic acids can be immobilized at multiple locations,...
US20100015726 SINGLE COLUMN IMMUNOLOGICAL TEST ELEMENTS  
A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test...
US20100248275 METHODS FOR PREDICTING OUTCOME IN TRAUMATIC BRAIN INJURY  
The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily...
US20090191220 METHODS FOR THE DIAGNOSIS AND TREATMENT OF CRITICALLY ILL PATIENTS WITH ENDOTHELIN, ENDOTHELIN AGONISTS AND ADRENOMEDULLIN ANTAGONISTS  
The ratio of concentrations of pro-adrenomedullin (pro-ADM)/pro-endothelin (pro-END) immunoreactivity in body fluids of critically ill patients is used as for the diagnosis, course control and...
US20110039273 METHOD FOR MEASURING DNA METHYLATION  
The present invention relates to a method of measuring the content of methylated DNA in a DNA region of interest in a genomic DNA contained in a biological specimen, and so on.
US20110118138 SOLID PHASE MULTI-ANALYTE ASSAY  
Compositions and methods for detecting the presence and/or amount of one or more analytes, including analytes such as drugs of abuse, are provided. The compositions include two or more analytes...
US20060194341 Library of compounds labelled with radiosotope  
Library of compounds or their pharmaceutically acceptable salts, each compound being associated with information on its chemical identity and structure, wherein at least two of the compounds is...
US20110201132 Optical Detection of Label-Free Biomolecular Interactions using Microreplicated Plastic  
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
US20070212734 Method for Distinguishing T(11Q23)/Mll-Positive Leukemias From t(11Q23)/Mll Negative Leukemia  
Disclosed is a method for distinguishing t(11q23)/MLL-positive leukemias from t(11q23)/MLL negative leukemias in a sample by determining the expression level of markers, as well as a diagnostic...
US20070054416 High density sample holder for analysis of biological samples  
A sample holder comprises a substrate microfabricated to define a multiplicity of microscopic islands defining sample support surfaces. At least one sump separates adjacent island surfaces and...
US20060292702 Method for modeling an simulating a biological system, and model carrying out this method  
A method of modeling and simulating a biological system comprising one or more tangible biological functional entities modeled by at least: a morphological occurrence comprising at least a...