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US20130116343 Salivary Protein Markers for Detection of Breast Cancer  
A method of diagnosing a patient's risk of breast cancer comprises measuring in a saliva sample from the patient a concentration of at least a first protein marker, wherein the first protein...
US20120088685 DIAGNOSIS OF NEUROPSYCHIATRIC AND BEHAVIOURAL DISORDERS  
This invention provides a method of identifying GAS infection as the cause of a neuropsychiatric or behavioural disorder in a patient, or of identifying a patient at risk of developing a...
US20150185232 INNATE IMMUNE PROTEINS AS BIOMARKERS FOR CNS INJURY  
The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein...
US20150110897 Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer  
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to...
US20110190149 NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS  
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
US20140141992 NEOEPITOPE DETECTION OF DISEASE USING PROTEIN ARRAYS  
A biosensor for use in detecting the presence of diseases, the biosensor comprising a detector for detecting a presence of at least one marker indicative of a specific disease. A method of...
US20120204276 METHODS RELATED TO A MUTATION IN COMPLEMENT FACTOR H-RELATED PROTEIN 5 IN PATIENTS WITH GLOMERULONEPHRITIS  
The invention relates to methods of regulating complement. In particular, the inventors have identified a relationship between a particular gene, CFHR5, and irregularities in complement...
US20120028835 SECERNIN-1 AS A MARKER FOR CANCER  
Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a...
US20120046185 PANEL OF BIOMARKERS FOR OVARIAN CANCER  
The present invention provides a panel of protein-based biomarkers that are useful in diagnosing ovarian cancer in a subject. In particular, the panel of biomarkers of the invention are useful to...
US20150173685 TRIAGE SCORING SYSTEM  
The application discloses a method of determining the severity of symptoms in a patient comprising (i) producing a triage score, such as an early warning score (EWS) modified early warning score...
US20150023950 2,6-Diaminopyridine Compounds Suitable for Treating Diseases Associated with Amyloid or Amyloid-Like Proteins or for Treating or Preventing Ocular Diseases or Conditions Associated with a Pathological Abnormality/Change in the Tissue of the Visual System  
The present invention relates to 2,6-diaminopyridine compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein and of diseases or...
US20130066088 METHODS FOR OBTAINING HIGH-YIELDING OIL PALM PLANTS  
Methods are provided for obtaining a high-yielding oil palm plant, comprising determining the level of a protein in mesocarp tissue of a fruit of a parental oil palm plant, determining whether...
US20120214710 METHOD OF PREDICTING RESPONSE TO THALIDOMIDE IN MULTIPLE MYELOMA PATIENTS  
A method of predicting response to thalidomide, or thalidomide analogs, in an individual with cancer, especially cancers for which thalidomide has been implicated as a treatment, such as Multiple...
US20120045849 SYSTEM AND METHOD TO MEASURE DISSOCIATION CONSTANTS  
A system and method for determining the dissociation constant for a particular ligand is disclosed. In accordance with certain embodiments, the method creates a chemical denaturation curve of a...
US20140162891 METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER  
The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using...
US20140308676 CITRULLINATED PROTEINS: A POST-TRANSLATED MODIFICATION OF MYOCARDIAL PROTEINS AS MARKER OF PHYSIOLOGICAL AND PATHOLOGICAL DISEASE  
Disclosed herein are methods for diagnosing cardiovascular disease. The methods comprise detection of citrullinated proteins.
US20140127731 Method And System For Detecting and Differentiating Cancer and Sepsis in Mammals Using Biomarkers  
The invention provides a method and system for developing and using diagnoses of cancer and sepsis in canine subjects using Thymidine kinase (TK), c-reactive protein (CRP), and C-type natriuretic...
US20110250592 METHODS FOR DETERMINING A PATIENT'S SUSCEPTIBILITY OF CONTRACTING A NOSOCOMIAL INFECTION AND FOR ESTABLISHING A PROGNOSIS OF THE PROGRESSION OF SEPTIC SYNDROME  
A method for determining a patient's susceptibility of contracting a nosocomial infection that includes obtaining a biological sample from the patient and extracting biological material from the...
US20140294843 DIAGNOSIS AND TREATMENT OF COPD  
Provided is a method for diagnosing and/or staging COPD based on detection of one or more histone proteins. In some embodiments, the histone protein is an H3.3 protein comprising a...
US20150099664 PROTEIN BIOMARKERS AND THERAPEUTIC TARGETS FOR AUTOIMMUNE AND ALLOIMMUNE DISEASES  
A method for characterizing the risk a subject will develop an autoimmune and/or alloimmune disease following tissue transplant includes obtaining a biological sample from the subject, wherein the...
US20110059549 METHODS AND SYSTEMS FOR PRODUCING NANOLIPOPROTEIN PARTICLES  
Provided herein are methods and systems for the production of a nanolipoprotein particle (NLP) that includes a scaffold protein a membrane forming lipid and optionally a target protein. At least...
US20120207708 BIOMARKERS FOR CANCER-RELATED FATIGUE AND USE THEREOF  
Described herein is the identification of genes that are significantly up- or down-regulated in patients suffering from cancer-related fatigue (CRF), providing a means for the diagnosis and...
US20150247871 RISK ASSESSMENT FOR ANTIBIOTICS TREATMENT IN PATIENTS SUFFERING FROM PRIMARY NON-INFECTIOUS DISEASE BY DETERMINING THE LEVEL OF PROCALCITONIN  
A diagnostic method for the identification of a subject suffering from a primary non-infectious disease having an increased risk of an adverse outcome potentially being induced by the...
US20120322082 BIOMARKER FOR AMYOTROPHIC LATERAL SCLEROSIS AND DIAGNOSTIC KIT AND METHOD USED THEREOF  
A diagnostic marker for determining of a patient with amyotrophic lateral sclerosis (ALS), comprising an autoantibody against a human protein HMGB1 is described. A diagnostic kit for determining...
US20130072397 METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF A TUMOR USING BCAT1 PROTEIN  
The present invention relates to methods for the diagnosis of a tumor, in particular a brain tumor, and for the estimation of a prognosis for patients afflicted with such tumor based on the...
US20130178388 Methods and Kits for the Diagnosis of Rheumatoid Arthritis  
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
US20110065609 Methods and Kits for the Diagnosis of Rheumatoid Arthritis  
The present invention relates to the identification and use of proteins with clinical relevance to rheumatoid arthritis (RA). In particular, the invention provides the identity of marker proteins...
US20130302909 ASSESSMENT OF IGF-1 LEVELS IN HIV-INFECTED SUBJECTS AND USES THEREOF  
Improved methods for determining normal IGF-1 levels in HIV infected subjects, based on a determination of the log of IGF-1 values obtained in blood-derived samples from a population of...
US20140237630 SCREENING METHOD  
The present invention provides a method of screening a mammal for the onset or predisposition to the onset of a neuropsychiatric disorder. More particularly, the present invention provides a...
US20110189700 CYR61 AS A BIOMARKER FOR DIAGNOSIS AND PROGNOSIS OF CANCERS OF EPITHELIAL ORIGIN  
Urinary Cyr61 protein levels are up regulated in patients that have cancers of epithelial origin, i.e. breast cancer and ovarian cancer. Accordingly, the present invention is directed to methods...
US20110136146 BIOASSAY FOR POLYQ PROTEIN  
The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diagnostic tools, for monitoring disease progression or for monitoring the efficacy of...
US20130237475 SYNTHETIC GENE FOR EXPRESSING SM-14 IN PICHIA PASTORIS, METHODS FOR PRODUCING AND PURIFYING SM-14 AND THE USE THEREOF AS A VACCINE AND DIAGNOSTIC MEDIUM  
The present invention pertains to the field of production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the...
US20120142033 METHOD FOR EXTRACTION AND PURIFICATION OF RECOMBINANT PROTEINS FROM TRANSGENIC PLANTS  
Extraction and purification of recombinant proteins rendered difficult to extract from transgenic plants by using an extraction solution containing reducing agents and surfactants or an extraction...
US20140273025 SYSTEM AND METHOD FOR DETERMINING RISK OF PRE-ECLAMPSIA BASED ON BIOCHEMICAL MARKER ANALYSIS  
A method for predicting risk of pre-eclampsia in a pregnant individual includes measuring one or more biochemical markers including an RBP4 biochemical marker in a blood sample obtained from the...
US20110269149 METHOD FOR QUANTIFICATION OF BODY INTERNAL CONCENTRATION OF PROTEIN-BASED DRUG  
It is an object of the invention to provide a method for rapid and accurate quantification of a sample in the human body of a patient. The invention relates to a method for quantification of the...
US20120225795 PROTEIN MARKERS FOR DETECTING LIVER CANCER AND METHOD FOR IDENTIFYING THE MARKERS THEREOF  
The present invention relates to the diagnosis of liver cancer. It discloses the use of protein ERBB3 and protein IGFBP2 in the diagnosis of liver cancer. It relates to a method for diagnosis of...
US20140256633 Relaxin Proteins For Use In The Diagnosis, Prevention or Treatment of Multiple Sclerosis  
The present invention relates to the use of one or more Relaxin proteins in methods for diagnoses and treatment of multiple sclerosis. The invention also provides compositions for use in...
US20140004544 FEN1 AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)  
An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an...
US20140004543 ASC AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)  
An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an...
US20130344516 ARMET AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)  
An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an...
US20110182928 VACCINE AGAINST AMYLOID FOLDING INTERMEDIATE  
The invention relates to an improved vaccine to treat Alzheimer's disease.
US20140273024 SYSTEM AND METHOD FOR DETERMINING RISK OF DIABETES BASED ON BIOCHEMICAL MARKER ANALYSIS  
A method for predicting risk of gestational diabetes mellitus (GDM) in a pregnant individual includes measuring one or more biochemical markers in a blood sample obtained from the pregnant...
US20130029333 Magnetic Bead Quantum Dot Nanoparticle Assay  
The present disclosure includes a magnetic bead (MB) quantum dot (QD) nanoparticle assay for detecting, capturing, separating, and/or quantifying a target in a sample.
US20120245235 CLASSIFICATION OF CANCERS  
A system for classifying a patient's cancer as belonging to one or more Cancer Modules of 1 of 15 different cancer types is provided. The Cancer Modules are useful to identify patient populations...
US20140272964 Blue Fluorescent Protein and Methods of Use Thereof  
This invention provides methods of making and using a fluorescent probe from the Sandercyanin protein as set forth in SEQ ID NO: 1 or SEQ ID NO: 2. In one embodiment, the invention provides a...
US20150133326 BIOMARKERS FOR RECOVERED HEART FUNCTION  
Disclosed herein is a method for determining recovered heart function in a subject based in the biomarker ceruloplasmin in patient samples. Also disclosed are computer systems, kits and software.
US20130317123 LARGE DELETIONS IN HUMAN PMS2 GENE AND USE THEREOF  
Large deletions have been identified in the PMS2 gene in patients. The large deletions predispose the patients to Lynch syndrome associated cancers.
US20130323751 Urine Biomarkers For Prediction Of Recovery After Acute Kidney Injury: Proteomics  
This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, renal...
US20110212464 PACAP AS A MARKER FOR CANCER  
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of...
US20140242725 MOLECULAR MARKERS FOR URINARY TRACT INFECTIONS  
The invention relates to an in vitro method for determining procalcitonin levels in plasma and urine as a diagnostic marker to identify patients with urinary tract infections, in vitro methods to...