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US20150093408 |
Lyme disease vaccine, genetic construct, recombinant protein, method for designing genetic construct, method for producing vaccine, method for producing recombinant proteins, use of recombinant proteins in the production of Lyme disease vaccine
The present invention relates to a Lyme disease vaccine, a genetic construct, recombinant protein, method for genetic construct design, method for vaccine delivery, method for recombinant proteins... |
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US20130158104 |
VECTORS AND SEQUENCES FOR THE TREATMENT OF DISEASES
The present invention provides new sequences, gene constructions, vectors and pharmaceutical compositions for the treatment of diseases and specially, for the treatment of mucopolysaccharidoses. |
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US20110257041 |
BIO-FIELD PROGRAMMABLE GATE ARRAY AND BIO-PROGRAMMABLE LOGIC ARRAY: RECONFIGURABLE CHASSIS CONSTRUCTION
Aspects of the invention relate to reconfigurable chassis that allow for rapid construction and optimization of biocircuits. |
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US20140315804 |
FUSION PROTEINS COMPRISING PDGF AND VEGF BINDING PORTIONS AND METHODS OF USING THEREOF
The present provides fusion proteins comprising PDGF and VEGF binding portions, and recombinant viral particles encoding the fusion proteins. Compositions comprising the fusion proteins and viral... |
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US20130337010 |
REASSORTANT BTV AND AHSV VACCINES
The present invention encompasses BTV and ASHV vaccines or compositions and methods of producing recombinant reassortant BTV and ASHV vectors and methods of vaccination against BTV and ASHV. |
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US20110039916 |
Helper Virus-Free Herpesvirus Amplicon Particles and Uses Thereof
The invention features new helper virus-free methods for making herpesvirus amplicon particles that can be used in immunotherapies, including those for treating any number of infectious diseases... |
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US20120083016 |
METHOD FOR TRACING GRAM-NEGATIVE BACTERIA INSIDE ANIMAL MODEL USING STABLE AND BIOLUMINESCENCE-BASED EXPRESSION SYSTEM THEREFOR
A method of creating a biotechnological product and an efficient and stable bio-luminescence vector which could be used for tracking Gram-negative bacteria when distributing inside animal body are... |
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US20120288893 |
SEED-SPECIFIC EXPRESSION VECTOR AND ITS CONSTRUCTION METHODS AND APPLICATIONS
A seed-specific expression vector and its construction methods and applications are disclosed. A fusion protein expression cassette consisting of Arachis hypogaea oleosin gene-apolipopoprotein... |
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US20140010834 |
NON-PATHOGENIC SEROTYPE 4 FOWL ADENOVIRUS (FADV-4) AND VIRAL VECTOR THEREOF
A high level replication fowl adenovirus (FAdV) isolate capable of reaching a viral titer of at least 3 log 10 is described. Said FAdV is a non-pathogenic strain of fowl adenovirus serotype 4,... |
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US20140356904 |
BACULOVIRUS EXPRESSION SYSTEMS
The present invention relates to an optimized baculovirus construct useful for the production of virus (-like) particles or viral vectors, in particular viral vectors for gene therapy. |
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US20110027309 |
COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of... |
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US20140235699 |
ADENO-PARVOVIRUS CHIMERA WITH ENHANCED ONCOLYTICAL POTENTIAL
Described is a chimerical adenovirus-parvovirus vector characterized in that it comprises the entire parvovirus genome inserted into a adenovirus genome, wherein: (a) the adenovirus genome is... |
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US20110045540 |
BACULOVIRUS EXPRESSION VECTOR AND METHOD THEREWITH FOR GENERATING IMMUNOGENICITY IN A HOST
A baculovirus expression vector achieves dual functions of (1) subunit vaccine by displaying the influenza surface protein for humoral immune responses; and (2) DNA vaccine by expressing influenza... |
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US20110207173 |
Self-Replicating Vector Lacking An Antibiotic-Resistance Gene
The subject matter of the present invention is a novel vector and the use thereof for producing a heterologous protein or a gene of interest, that can be used, for example, in the context of an... |
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US20110212493 |
PERFUSION BIOREACTORS, CELL CULTURE SYSTEMS, AND METHODS FOR PRODUCTION OF CELLS AND CELL-DERIVED PRODUCTS
The present invention includes perfusion bioreactors, automated cell culture systems, and methods for production of cells and cell-derived products. |
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US20140287938 |
RECOMBINANT VIRUS AND PREPARATIONS THEREOF
The present invention generally relates to methods and compositions used delivery of gene editing compositions including transcriptional effectors with parvovirus and preferred methods for making... |
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US20120328590 |
ANTI-CANCER THERAPEUTIC STRATEGY TO OVERCOME CANCER RESISTANCE AND TO ENABLE TAILORING TREATMENT TO PATIENTS
A gene construct comprising a programmed-cell-death executioner gene having a nuclear localization signal, a deleted signal peptide, an inhibitor-resistant binding site, a promoter, and an... |
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US20120042409 |
PLANT TRANSFORMATION USING DNA MINICIRCLES
The invention provides methods and compositions for producing and using minicircle DNA molecules that are useful for plant transformation. The invention also provides methods for transforming... |
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US20110129487 |
PLASMIC PRODUCTION AND EXPRESSION OF RECOMBINANT PROTEINS IN CELLS GROWN WITHOUT ANTIBIOTICS
The invention relates to a mutated cell such as a bacteria or yeast in which the thyA gene coding thymidylate synthase includes a nonsense codon, preferably the amber codon, said nonsense codon... |
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US20130109061 |
HYPERPROLIFERATIVE RECOMBINANT CELL
A method increases the growth of a cell by a deletion or one or more mutation(s) in the tldD and/or tldE genes, coupled with one or more mutation(s) in dam or a partial deletion or deletion of the... |
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US20110098200 |
Methods using dsdna to mediate rna interference (rnai)
The present invention provides methods of producing dsDNA molecules that can be used to mediate RNA interference (RNAi). These methods include the production of hairpin DNAs including random... |
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US20120129223 |
DNA LOADED SUPPORTED GOLD NANOPARTICLES, PROCESS FOR THE PREPARATION AND USE THEREOF
The present invention relates to DNA loaded gold nanoparticles embedded in sharp carbonaceous carriers useful for higher DNA delivery efficiently into plants. These nanogold embedded carbon... |
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US20140322760 |
METHOD FOR PRODUCING VIRUS VECTOR FOR GENE TRANSFER
The present invention discloses a cell system, as a host cell to be infected with an F gene-deficient virus, which can constitutively and stably express the F protein, and a method for producing... |
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US20110091501 |
Recombinant Rhinovirus Vectors
The invention provides rhinovirus vectors, which can be used in the delivery of immunogens, such as influenza virus immunogens, and corresponding compositions and methods. |
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US20130195914 |
Expression Of Positive Sense Single Stranded RNA Virus And Uses Thereof
The invention relates to the fields of viruses, vaccines and compounds and methods for expression. In particular, the invention includes methods and agents capable of producing quantities of a... |
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US20140004568 |
Method of Viral Production in Cells
A method of using a cell to produce virus is provided involving growing cells under hyperosmotic conditions during growth phase of the cells, infecting or transfecting the cells grown under... |
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US20140170709 |
VECTOR FOR GENE THERAPY
The present invention provides a retroviral vector containing a transcription unit comprising a transcription regulatory sequence and a gene encoding a polypeptide having single-stranded... |
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US20110165629 |
Recombinase-Based Methods for Producing Expression Vectors and Compositions for Use in Practicing the Same
Methods are provided for producing a vector that includes at least one splicable intron. In the subject methods, intron containing vectors are produced from donor and acceptor vectors that each... |
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US20150225732 |
E. COLI PLASMID DNA PRODUCTION
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined... |
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US20150203854 |
E. COLI PLASMID DNA PRODUCTION
General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined... |
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US20120225445 |
SEBOCYTES, SEBOCYTE CELL LINES AND APPLICATIONS THEREOF
Adipose cells (sebocytes) are described, The invention especially relates to sebaceous gland cells and to a sebaceous gland cell line with the property of being continuously grown over many... |
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US20140051125 |
Stable Production of Lentiviral Vectors
The present invention provides new stable packaging cell lines and producer cell lines as well as methods to obtain them, and a new method to produce lentiviral vectors using such cell lines. New... |
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US20110311499 |
Secretion System and Methods for its Use
The present invention provides reagents and methods for inhibiting bacterial infection and abnormal cell growth, as well as for selection cloning of nucleic acid inserts. |
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US20130298265 |
METHOD OF DUAL-ADAPTER RECOMBINATION FOR EFFICIENT CONCATENATION OF MULTIPLE DNA FRAGMENTS IN SHUFFLED OR SPECIFIED ARRANGEMENTS
The present invention relates to methods of assembling a plurality of genetic units to form synthetic genetic constructs. This method involves appending universal adapter oligonucleotides and... |
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US20150191735 |
DNA PLASMIDS WITH IMPROVED EXPRESSION
The present invention relates to the production and use of covalently closed circular (ccc) recombinant plasmids, and more particularly to vector modifications that improve expression of said DNA... |
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US20110269184 |
METHOD FOR CONTROLLING PLASMID COPY NUMBER IN E.COLI
Host vector system and methods for plasmid DNA and recombinant protein production. The system allows copy number control of a ColE1 plasmid in E. coli by an RNA molecule that is transcribed from... |
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US20100055237 |
Novel Enzymes for Use In Enzymatic Bleaching of Food Products
The present invention relates to novel polypeptides according to caroase 01-05 or any functional equivalents of any of them, suitable for use in a method for preparing a food products having... |
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US20110059485 |
Plasmids from Thermophilic Organisms, Vectors Derived Therefrom, and Uses Thereof
The present invention is directed to a replicative, thermostable plasmid. In particular, the present invention is directed to a replicative, thermostable plasmid comprising a sequence derived from... |
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US20110269116 |
Cell Line From Rousettus As Host Cell For Pathogen Amplification
The present invention relates to permanent cell lines from chiropterans suitable for amplification and production microbial agents, preferably viruses, and its use for diagnostic or therapeutic... |
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US20140193858 |
PRODUCTION OF VIRAL VECTORS
The present invention relates to methods and compositions for the production of viral vectors. In particular, the present invention provides methods and compositions for faster, higher titer and... |
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US20120053223 |
COMPOSITIONS AND METHODS FOR TREATING RETROVIRUS INFECTIONS
The present invention relates to at least one nucleic acid (i) comprising or consisting of or (ii) encoding a nucleic acid comprising or consisting of, a sequence selected from the group... |
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US20140308711 |
ENZYMATIC PHOSPHOROTHIOATION OF DNA OR RNA
This invention relates to methods, compositions, and kits for enzymatic phosphorothioation of the sugar-phosphate backbone of nucleic acids. The invention allows for phosphorothioation of... |
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US20080102496 |
Expression of Nitrile Hydratases in a Two-Vector Expression System
The present invention relates to a novel system for expressing nitrile hydratase. In this system, the nitrile hydratases, which are composed of subunits, are formed such that the respective... |
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US20100304445 |
NUCLEIC ACID PACKAGING SYSTEM
The present invention relates to cloning target nucleic acids using phage packaging mechanisms. Packaging initiation sites may be introduced into the target DNA. Components of a phage packaging... |
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US20090042257 |
Adenoviral fiber exchange shuttle system
The instant invention provides methods and compositions for generating recombinant adenoviral vectors. The invention also provides kits comprising for the generation of recombinant adenoviral vectors. |
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US20120088271 |
Use of an Endogenous 2-Micron Yeast Plasmid for Gene Over Expression
Methods and compositions for making stable recombinant yeast 2 μm plasmids are provided. Homologous recombination is performed to clone a nucleic acid of interest into the yeast 2 μm plasmid.... |
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US20080318283 |
Fermentation Process for Continuous Plasmid Dna Production
A continuous process is described for the production of microbial plasmid DNA for use in biopharmaceutical and biotechnological applications. The process consists of: first growing microbial cells... |
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US20100184832 |
Construction of Recombinant Virus Vaccines by Direct Transposon-Mediated Insertion of Foreign Immunologic Determinants into Vector Virus Proteins
The invention provides viral vectors, such as chimeric flavivirus vectors, including foreign peptides inserted into the target proteins of the vectors, methods of making and using these vectors,... |
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US20130330767 |
Cell Lysis Process
A process for cell lysis is provided. The process comprises passing a mixture comprising a suspension of cells and a lysis reagent through a flow-through reactor, wherein the mixture passes... |
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US20110262974 |
Novel enzymes for use in enzymatic bleaching of food products
The present invention relates to novel polypeptides according to caroase 01-05 or any functional equivalents of any of them, suitable for use in a method for preparing a food products having... |