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US20120028261 PROTEIN BIOMARKERS FOR SOFT TISSUE DISEASE DIAGNOSIS AND AS THERAPEUTIC TARGETS FOR ORAL CARE INTERVENTION  
Methods for identifying compounds useful for treating diseases or conditions of the oral cavity are described herein.
US20130309691 USE OF HEAT-RESISTANT BIOTIN-BINDING PROTEIN, AND SOLID SUPPORT HAVING THE PROTEIN ATTACHED THERETO  
The present invention relates to a solid support having a heat-resistant biotin-binding protein attached thereto. The present invention also relates to the use of the solid support of the present...
US20110124010 DIAGNOSTIC METHOD  
A method of detecting the presence, or monitoring the severity of a condition characterised by the presence of fragments of a marker protein in the brain of a patient. The method comprises: (i)...
US20120201837 USE OF EIF3M FOR THE DIAGNOSIS AND TREATMENT OF CANCER  
Disclosed are a cancer marker-detecting composition comprising an agent for measuring an mRNA or protein expression level of eIF3m, a cancer diagnosis kit comprising the same, a method for...
US20120115165 BIOMARKERS FOR DETECTION AND DIAGNOSIS OF HEAD AND NECK SQUAMOUS CELL CARCINOMA  
Novel, sensitive and specific markers and methods for diagnostics and monitoring of head and neck squamous cell carcinoma (HNSCC) are provided. Kits and methods for the use of hyaluronic acid,...
US20150064717 METHOD FOR STAINING TISSUE  
Provided is a method for staining a tissue enabling highly precise staining, by which the expression amount and/or the location of a biological substance in a tissue sample can be detected with a...
US20120064543 METHOD FOR DETECTING SUBSTANCE IN BIOLOGICAL SAMPLE  
The present invention provides a method for detecting a substance in a biological sample, a carrier for using in the method, and a kit. The method of the present invention according to an...
US20110296540 ASSAY FOR SCREENING ANTIDEPRESSANTS  
This invention provides a method for identifying a small molecule as an antidepressant, a method for identifying a small molecule as an anxiolytic, and a method for identifying a small molecule as...
US20150031626 ADAM22 FOR USE AS A PROGNOSTIC VARIABLE, AND TARGET FOR THERAPY, OF A METASTATIC BREAST CANCER DISEASE  
A method of diagnosing metastatic potential of a breast cancer in an individual with breast cancer is described. The method comprises a step of assaying a breast cancer tumour sample from the...
US20140179806 BIOMARKERS FOR EARLY DETERMINATION OF A CRITICAL OR LIFE THREATENING RESPONSE TO ILLNESS AND/OR TREATMENT RESPONSE  
The invention relates to the use of novel biomarkers and biomarker combinations having utility in the early determination of an individual's critical and/or life threatening response to illness...
US20120065089 Method For Detecting And Distinguishing Intrahepatic Cholangiocarcinoma  
Disclosed are a method for early, sensitively and reliably detecting and distinguishing intrahepatic cholangiocarcinoma in a malignant tumor occurring primarily in the liver in a simple way, and a...
US20130183318 METHODS AND COMPOSITIONS FOR THE INHIBITION OF STAT5 IN PROSTATE CANCER CELLS  
The present invention relates to compositions and methods for the treatment of prostate cancer. In certain embodiments, the invention relates to compositions and methods for the inhibition of...
US20120321639 METHODS AND COMPOSITIONS FOR THE INHIBITION OF STAT5 IN PROSTATE CANCER CELLS  
The present invention relates to compositions and methods for the treatment of prostate cancer. In certain embodiments, the invention relates to compositions and methods for the inhibition of...
US20120252904 MITF AS A MARKER FOR PREDISPOSITION TO CANCER  
The present invention relates to a mutant of MITF which is useful as a marker for predisposition to the development of cancer and to uses thereof in diagnosis and preventive treatments,...
US20110319293 SYNTHETIC PROTEASE SUBSTRATES, ASSAY METHODS USING SUCH SUBSTRATES AND KITS FOR PRACTICING THE ASSAY  
Synthetic protease substrates and methods which facilitate the identification of substrates of a protease, particularly ubiquitin, ubiquitin-like, or proteasome protein are provided.
US20110300099 MULTI-LEVEL SPECIFIC TARGETING OF CANCER CELLS  
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more...
US20120164660 METHOD FOR USING A DIAGNOSTIC AGENT WHICH INCLUDES A CALCIUM BINDING PROTEIN ASSAY REAGENT AND ASSAY METHOD FOR CALCIUM BINDING PROTEIN  
A bovine- or human-derived calcium-binding protein with a prescribed amino acid sequence, a method for its production, and antibodies against the protein and uses thereof.
US20120142023 PROTEINS AND METHOD FOR DETECTION OF LYME DISEASE  
Recombinant B. burgdorferi proteins, representative of the life cycle, are membrane-immobilized to capture antibodies in biological samples. Lateral flow technology incorporating gold colloid...
US20100081148 Urinary Biomarkers To Predict Long-Term Dialysis  
This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term...
US20050142616 Diagnostic test for neuropsychiatric systemic lupus erythematosus  
This invention provides methods for assessing the likelihood that a patient is suffering neuropsychiatric systemic lupus erythematosus by detecting autoantibodies in a sample from the patient....
US20130045163 TREATMENT OF METASTATIC TUMORS  
The present invention is directed to methods and methods for the treatment, inhibition and/or reduction, and detection of metastatic tumors. In some embodiments, the inventive methods include...
US20120177581 BYSTANDER IMMUNE SUPPRESSION AS A PREDICTOR FOR RESPONSE TO A VACCINE  
The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for selecting candidate vaccine...
US20120077205 METHOD FOR PRODUCING COMPLEX OF BIOTIN-LABELED CYPRIDINA (CYPRIDINA NOCTILUCA) LUCIFERASE WITH STREPTOAVIDIN AND METHOD FOR STABILIZING THE SAME  
The present invention relates to a method for producing Cypridina luciferase labeled with hydrophilic biotin, characterized in that a biotin reagent containing a polyalkylene glycol structure as a...
US20130251731 Tau Acetylation in the Pathogenesis of Alzheimers Disease and Other Related Tauopathies  
The present invention relates to biomarkers and diagnostic methods for Alzheimer's disease and other neurodegenerative disorders. The invention also provides compositions for detecting the...
US20110319470 Diagnosis, prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling  
Provided herein is a method for gene expression profiling multiple myeloma patients into distinct subgroups via DNA hybridization and hierarchical clustering analysis of the hybridization data...
US20130130278 DETECTION OF RISK FOR PREGNANCY-RELATED MEDICAL CONDITIONS  
Generally, there is provided a method of determining risk of determining intrauterine growth restriction (IUGR)/fetal growth restriction (FGR). The method comprises obtaining a sample from a...
US20120071340 BIOMARKERS  
The invention relates to a method of diagnosing or monitoring major depressive disorder.
US20060281101 Biobriefcase  
A bio-briefcase system for analyzing a sample for the presence of biological agents. The bio-briefcase system comprises a housing, an immunoassay section operatively connected to the housing,...
US20070042438 Scd4ol and placental growth factor (plgf) used as a biochemical marker combination in cardiovascular diseases  
The invention relates to novel markers of vascular inflammation and combinations thereof as diagnostic and prognostic tools in patients with cardiovascular diseases. The markers also act as tools...
US20140378558 BIOMARKER FOR DETECTING CANCER  
Methods for detecting colorectal cancer in a subject by detection of a galactose-containing 40 kDa molecule in a serum sample from the subject. Methods for quantifying the amount of a...
US20050202508 Biomarker for Parkinson's disease  
This invention provides methods for assessing the likelihood that a patient is suffering from Parkinson's disease by detecting a biomarker in a sample from the patient. This invention also...
US20120094308 KIT AND METHOD FOR THE PREMORTEM IN VITRO DETECTION OF ALZHEIMER'S DISEASE  
Kit and method for the pre mortem in vitro detection of Alzheimer's disease The invention relates to a detection kit for Alzheimer's disease based on the vitro identification of the presence of...
US20110275094 PHOSPHORYLATED FMS-RELATED TYROSINE KINASE 3 BIOMARKER ASSAY  
Provided herein are methods for detecting the presence of human pFLT3 in a sample. An exemplary assay provided herein is an ELISA method (e.g., sandwich ELISA). Also provided herein are methods...
US20120009595 BINDING OF AGGREGATED FORMS OF PROTEINS  
Aggregating proteins such as IgG, are bound selectively in the presence of the non-aggregated protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine...
US20150168402 NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA  
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
US20070254303 Methods for assessing the efficacy of treatment with a glucocorticoid  
The invention relates to methods for assessing the efficacy of treatment with a glucocorticoid by determining the amount of MetAP-2.
US20060057647 Detection and identification of saxiphilins using saxitoxin-biotin conjugates  
A method for capturing a saxiphilin to allow for detection, characterisation, isolation an/or purification of said saxiphilin or its ligand, comprising: (1) providing a PST conjugate comprising a...
US20120164661 METHODS AND REAGENTS FOR SIGNAL AMPLIFICATION  
The present invention provides reagents containing binding moieties conjugated to dextran moieties, methods of making such reagents, and use of such reagents in a variety of molecular and cellular...
US20150080250 SOLID SUPPORT AND METHOD FOR DETECTING AN ANALYTE IN A SAMPLE  
A solid support for detecting the presence of an analyte in a sample at or above a predetermined threshold comprises: a competitive analyte within said solid support, wherein said competitive...
US20090176213 STABILIZATION OF SOLID SUPPORT ASSAY REAGENTS  
Reagents are disclosed for use in assays for analytes. The reagents are dry assay reagents that may be readily reconstituted for use in the assays. The dry assay reagents comprise a solid support...
US20130189707 METHOD OF DETERMINATION OF AUTOANTIBODY LEVEL BY MEANS OF ENZYME IMMUNOASSAY  
The method for quantitative determination of the level of natural autoantibodies in human biological fluids, when as a solid phase of physical sorption is used the solid phase of physical...
US20070048807 Diagnostic test kits with improved detection accuracy  
A diagnostic test kit that provides an integrated system for accurately detecting a test analyte over a broad range of possible concentrations is provided. One feature of the integrated system is...
US20110306557 NEURAL REGENERATION PEPTIDES AND METHODS FOR THEIR USE IN TREATMENT OF BRAIN DAMAGE  
The invention discloses a family of neuronal migration-inducing, proliferation-promoting and neurite outgrowth promoting factors, termed NRP compounds, and provides compositions and methods for...
US20150064718 ORGANIC/INORGANIC MAGNETIC COMPOSITE, METHODS OF MAKING AND USE THEREOF  
An organic/inorganic composite is provided. The organic/inorganic composite materials are sufficiently hard and brittle to be ground to form particles suitable for biological or chemical...
US20090010839 Avidin dimers effective in increasing the concentration of radioactive biotin in pretargeted radioimmunotherapy  
Dimers of avidin and streptavidins (diavidins) are described wherein the linker is suberate, which in turn, is bound to different functional groups (—NH2 o-COOH) of avidin. As compared to avidin,...
US20120021416 BIOLAYER INTERFEROMETRY MEASUREMENT OF BIOLOGICAL TARGETS  
Disclosed are methods and compositions for the ultrasensitive detection of oligonucleotides, proteins, protein complexes, biomolecules, and infectious agents using a peroxidase driven deposition...
US20060040258 Water-soluble conjugates and methods of preparation  
The present invention provides water-soluble conjugates and methods of using them in diagnostic and detection assays. Devices for performing detection and quantitation assays are also provided. In...
US20140273009 COMPOSITIONS AND METHODS FOR PERFORMING ASSAYS  
The disclosure relates to compositions for use in assays, the compositions comprising at least one latent fluorophore including at least one enzyme-reactive quenching group and a conjugative...
US20120107834 ENCAPSULATED REAGENTS AND METHODS OF USE  
The present invention contemplates use of encapsulated aqueous and non-aqueous reagents, solutions and solvents and their use in laboratory procedures. These encapsulated aqueous or non-aqueous...
US20060263832 Patterning of centrosomes and centrosome fragments as templates for directed growth of microtubules  
The present invention relates to a new process to direct the growth and direction of polymerization of microtubules using patterned centrosomes or centrosome fragments on a surface. Incorporation...

Matches 1 - 50 out of 237 1 2 3 4 5 >