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US20140357521 TOOLS AND METHODS FOR EXPRESSION OF MEMBRANE PROTEINS  
The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or...
US20100331192 SURFACE DISPLAY OF RECOMBINANT PROTEINS IN LOWER EUKARYOTES  
Methods for display of recombinant proteins or protein libraries on the surface of lower eukaryotes such as yeast and filamentous fungi are described. The methods are useful for screening...
US20140357508 Cell Surface Display, Screening and Production of Proteins of Interest  
Aspects of the invention provide compositions and methods for displaying engineered polypeptides on a cell surface. According to aspects of the invention, immobilized polypeptides can be screened...
US20110065131 ASSAYS FOR MUTAGENESIS DETECTION  
The disclosure provides methods, systems, and kits for assaying an agent for mutagenic properties. The methods systems and kits utilize a DEL selectable marker and a colorimetric detection...
US20100279318 METHOD OF IDENTIFYING TRANSMEMBRANE PROTEIN-INTERACTING COMPOUNDS  
A method for screening compounds for their ability to interact with transmembrane proteins is provided. Also provided is a method for determining whether proteins such as transmembrane proteins...
US20140323348 EXPRESSION OF G-PROTEIN COUPLED RECEPTORS (GPCRs)  
Disclosed are methods of promoting and/or enhancing G-Protein Coupled Receptor (GPCR) localization to the cell membrane and/or cell surface; methods of promoting and/or enhancing GPCR functional...
US20110003306 IDENTIFICATION OF ANTIBIOTIC RESISTANCE USING LABELLED ANTIBIOTICS  
Subject of the present invention is a method for detection of an antibiotic resistance in a micro-organism comprising the steps of exposing suspected micro-organism to a labelled (fluorescent)...
US20140248605 BACTERIAL CHALLENGE MODEL IN CATTLE USING A TRANS- AND INTRA-DERMAL ROUTE TO INFECT PERIPHERAL LYMPH NODES  
The present invention includes a method of observing and evaluating bacterial infections within the lymph nodes of animals presented for harvest comprising: inoculating at one or more sites of an...
US20150010903 Real Time Diagnostic Assays Using an Evanescence Biosensor  
The present invention relates to a method for the detection of a substance in an aqueous, physiological or chemical liquid using the evanescence field method, and to a diagnostic device for...
US20080118911 Test Device for the In-Vitro Diagnosis of Multi-Analyte Tests and Use Thereof  
The present invention generally relates to the diagnosis of diseases and in particular novel methods and devices for an improved use of markers that are associated with diseases to be diagnosed....
US20140031292 Yeast Cell Surface Display of Proteins and Uses Thereof  
The present invention provides a genetic method of tethering polypeptides to the yeast cell wall in a form accessible for binding to macromolecules. Combining this method with...
US20140178884 METHOD OF DIAGNOSING AND TREATING AN ASPERGILLUS SPECIES-ASSOCIATED CONDITION  
Disclosed herein are methods of diagnosing, monitoring and treating an Aspergillus species-associated condition, such as Aspergillus fumigatus (Af)-associated condition, including aspergillosis,...
US20140004538 METHOD FOR DIAGNOSING INVASIVE CANDIDA INFECTIONS  
The present invention concerns an in vitro method for diagnosing invasive candidiasis (IC) in a subject which comprises detecting the presence of a Candida glycan and detecting the presence of...
US20130096281 METHODS AND COMPOSITIONS FOR DISPLAYING A POLYPEPTIDE ON A YEAST CELL SURFACE  
Provided herein are methods and compositions for use in displaying a polypeptide (e.g., an antibody polypeptide or an antibody polypeptide fragment) on the surface of a yeast cell. Exemplary yeast...
US20110021374 NMR DEVICE FOR DETECTION OF ANALYTES  
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with...
US20110020788 NMR DEVICE FOR DETECTION OF ANALYTES  
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with...
US20110020787 NMR DEVICE FOR DETECTION OF ANALYTES  
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with...
US20100095408 Anti-Pathogen Systems  
Provided is a system for protecting plants from attack by pests, including pathogens such as fungi. Specifically, a plant defensin is provided in conjunction with a protease inhibitor protects a...
US20100330590 ASSAYS USING CHIMERIC T1R3 TASTE RECEPTOR POLYPEPTIDES  
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in...
US20110223618 ASSAYS USING CHIMERIC T1R POLYPEPTIDE  
This invention relates to chimeric taste receptors comprising the extracellular portion of one T1R or a variant or fragment thereof, either T1R1 or T1R2, and the transmembrane portion of another...
US20110097741 PARTIAL T1R2 NUCLEIC ACID SEQUENCE, RECEPTOR PROTEIN AND ITS USE IN SCREENING ASSAYS  
A novel sweet receptor protein, corresponding nucleic acid sequence, expression vectors, transfected host cells, and screening methods for modulators including ligands of the sweet taste response...
US20110039256 DETECTION METHOD  
A method for detecting the presence of a diagnostic moiety indicative of exposure to an infectious organism in a biological sample taken from a human or animal, said method comprising; (a) adding...
US20070275397 Detection of molecular interactions using a reduced affinity enzyme complementation reporter system  
Methods and compositions for detecting molecular interactions are provided. Aspects of the invention include the use of a reduced affinity enzyme complementation reporter system. Also provided are...
US20140323340 SENSITIVE AND RAPID DETERMINATION OF ANTIMICROBIAL SUSCEPTIBILITY  
The present invention relates to moving microorganisms to a surface, where they are grown in the presence and absence of antimicrobials, and by monitoring the growth of the microorganisms over...
US20090305312 In Vitro Diagnostic Method and Kit for an Aspergillus Infection  
The present invention relates to a method for the in vitro diagnosis of an Aspergillus infection by determining in the serum or plasma sample of a subject the quantity of antibodies directed...
US20140170639 TARGET DETECTION  
The invention generally relates to methods for indicating whether an assay for isolating targets is properly isolating and detecting targets. Methods of the invention involve obtaining a sample...
US20140342932 FUNCTIONAL CELL SURFACE DISPLAY OF LIGANDS FOR THE INSULIN AND/OR INSULIN GROWTH FACTOR 1 RECEPTOR AND APPLICATIONS THEREOF  
Systems for making, identifying, and selecting recombinant cells that express a ligand for the insulin receptor (IR) or insulin growth factor I (IGF-1) receptor are described. In general,...
US20130336892 CHIMERIC T1R TASTE RECEPTOR POLYPEPTIDES AND NUCLEIC ACID SEQUENCES ENCODING AND CELL LINES THAT EXPRESS SAID CHIMERIC T1R POLYPEPTIDES  
The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric...
US20130309693 POLYPEPTIDES FOR MICROBIAL DETECTION  
Polypeptides which can be activated to cause the formation of pores in a lipid membrane are disclosed. Also disclosed are polypeptide compositions for the detection of target microorganisms and...
US20070196877 Rapid, low-cost assay for detecting brettanomyces and other spoilage yeast in wine  
In one aspect, the present invention relates to a rapid, sensitive and cost-effective immunoassay for the detection of Brettanomyces yeast in wine.
US20110053187 SILICA-BASED MATERIAL FOR DETECTION AND ISOLATION OF CHITIN AND CHITIN-CONTAINING MICROORGANISMS  
The subject invention provides silica-based material that has high affinity to chitin, chitin derivatives and chitin-containing microorganisms at an acidic pH. In an embodiment, the silica-based...
US20120202191 DETECTION METHOD BASED ON TIME RESOLVED REAL TIME FLUORESCENT ENERGY TRANSFER (TR-FRET)  
A method for detecting the presence of a diagnostic moiety indicative of exposure to an infectious organism in a biological sample taken from a human or animal, said method comprising use of a...
US20110143374 Methods to Identify Modulators of the Interaction Between Dextromethorphan and the Bitter Taste Receptor TAS2R46  
TAS2R46 was identified as a dextromethorphan-binding bitter taste receptor. Novel methods to identify modulators and in particular inhibitors to the bitter taste of dextromethorphan are provided.
US20150064112 USE OF T1R3 VENUS FLYTRAP REGION POLYPEPTIDE TO SCREEN FOR TASTE MODUALTORS  
The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or sub-units thereof. The present invention also relates to the use of hetero-oligomeric...
US20100129835 Methods for Selecting Improved Strains  
The present invention relates to a system for improving a strain of filamentous fungus that is useful in producing an enzyme of interest such as a cellulase. The invention involves generating...
US20140315219 Rapid Enzyme-Linked Immunosorbant Assay for Detection and Identification of Pathogens and Determination of Antimicrobial Susceptibility  
The present invention provides a rapid, highly sensitive and specific enzyme-linked immunosorbent assay (ELISA), referred to as N-Assay, a device, and a kit, for detection and identification of...
US20120156695 MICROORGANISM FOR EXPRESSING A HUMAN MEMBRANE PROTEIN  
The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced...
US20130011862 RAPID PROCESS FOR DETECTION OF MICROORGANISMS WITH MAGNETIC PARTICLES  
The present invention relates to processes for the rapid detection, semi-quantification and quantification of live microorganisms in solutions or suspensions using immunomagnetic particles,...
US20100275284 INHIBITOR OF APOPTOSIS PROTEINS AND NUCLEIC ACIDS AND METHODS FOR MAKING AND USING THEM  
The invention provides polypeptides comprising inhibitor of apoptosis protein (IAP) family members, such as BmIAP initially derived from Bombyx mori BmN cells, and nucleic acids encoding them, and...
US20130108642 IMMUNOTHERAPY AND DIAGNOSIS OF MUCORMYCOSIS USING CotH  
The invention provided Mucorales CotH polypeptides and encoding nucleic acid molecules. The Mucorales CotH polypeptides and encoding nucleic acids can be advantageously used to diagnose, treat or...
US20110311991 Methods of Identifying Modulators of the Bitter Taste Receptor TAS2R44  
Steviol glycosides have been discovered to bind the bitter taste receptor TAS2R44. Novel methods of identifying modulators and in particular inhibitors to the bitter taste of steviol glycosides...
US20080311595 Rapid fungal detection assay and product  
The present invention relates to the use of an assay and product for rapid detection of fungi in a variety of samples suspected of containing fungi, particularly swab samples from the human...
US20100285451 DETECTION OF SUB-CELLULAR COMPARTMENT LOCALIZATION OF A MOLECULE USING A REDUCED AFFINITY ENZYME COMPLEMENTATION REPORTER SYSTEM  
Methods and compositions for detecting the sub-cellular localization of a molecule are provided. Aspects of the invention include detecting translocation of a cell-surface receptor to a...
US20120003661 METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS  
Methods and devices are provided for the rapid and specific detection of target microorganisms, cells, and the like. In one embodiment, the methods involve contacting a target microorganism (e.g.,...
US20060199234 Method of diagnosing wood decay and decay diagnostic agent  
The invention provides a simple method which enables precise diagnosis of wood decay at an early stage of decay and an agent used for the diagnosis method. The invention provides a method for...
US20080038286 Glycosylated polypeptides produced in yeast mutants and methods of use thereof  
The invention provides various high mannose glycosylated polypeptides that are useful in a vaccine formulations. The invention also provides methods for making such glycosylated polypeptides and...
US20140186334 SURFACE, ANCHORED FC-BAIT ANTIBODY DISPLAY SYSTEM  
The present invention provides, in part, an antibody display system that simultaneously uses a secretion and a display mode. A bait complexed with a monovalent antibody fragment can be expressed...
US20090246806 COCCIDIOIDES ANTIGEN IMMUNOASSAY  
The present disclosure relates to methods for detecting a Coccidioides in a physiological specimen. Methods, materials and kits relating to the detection of Coccidioides antigen by improved EIA...
US20100035234 VACCINE ASSAYS  
The present invention is directed to methods, assays and compositions for implementing such methods and assays for assessing efficacy of individual components in multi-component vaccines and for...
US20070020711 Fungal antigen immunoassay  
The present disclosure relates to methods for detecting a fungal antigen in a physiological specimen. The present invention includes methods and materials for testing for antigens associated with...

Matches 1 - 50 out of 167 1 2 3 4 >