AcclaimIP-ad

Match Document Document Title
US20110034347 Signatures Associated with Rejection or Recurrence of Cancer  
Methods and tools for assessing the prognosis for patients following treatment of primary tumors are provided. The methods involve identifying immune-related genetic markers whose differential...
US20110020805 MUTATIONAL ANALYSIS OF CHRONIC MYELOPROLIFERATIVE DISORDERS  
The invention relates to molecular assays, reagents and kit for the mutational analysis, for diagnostic and prognostic purposes, of chronic myeloproliferative disorders, a group of neoplastic...
US20110014191 BREAST CANCER EXPRESSION PROFILING  
The present invention relates to a method for analyzing cancer. e.g., breast cancer including detection of differential expression of at least one of the 16 genes encoding serine/threonine kinases...
US20110045482 SCREENING METHODS FOR IDENTIFYING TARGET ANTIFUNGAL GENES AND COMPOUNDS BY DETECTING CELL SURFACE GLYCOPROTEINS  
The present invention relates to an assay method that can be used for high-throughput detection of cell surface glycoproteins. Specifically, the secretion of a chimeric glycoprotein reporter...
US20110055937 Keratin 8 Mutations are Risk Factors for Developing Liver Disease of Multiple Etiologies  
Keratin 8 and 18 (K8/K18) mutations are shown to be associated with a predisposition to liver or biliary tract disease, particularly noncryptogenic hepatobiliary disease. Unique K8/K18 mutations...
US20110085990 ORAL CARE METHODS AND SYSTEMS  
This, intention relates to methods of assessing the biofiora of the mouth and of providing appropriate treatment utilizing a basic amino acid in accordance with the assessment.
US20100298151 EXOSOME-ASSOCIATED MICRORNA AS A DIAGNOSTIC MARKER  
The presently disclosed subject matter provides methods of diagnosis of cancer or adverse pregnancy outcomes in a subject by measuring amounts of one or more microRNAs present in cancer-derived...
US20110076685 METHOD FOR IN VITRO DETECTION AND DIFFERENTIATION OF PATHOPHYSIOLOGICAL CONDITIONS  
The present invention relates to the use of defined polynucleotides to form at least one multi-gene biomarker for producing a multiplex assay as a tool for in vitro detection and/or early...
US20110045480 METHODS FOR PREDICTING THE EFFICACY OF TREATMENT  
Clinical tests for testing therapeutic sensitivity of cancerous breast tissue and methods and kits for performing the same are described herein. Embodiments of the present invention are directed...
US20110059851 SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair  
The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is...
US20110230372 GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUTCOME PREDICTION IN PEDIATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA  
The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high...
US20100303832 GENES AND POLYMORPHISMS ASSOCIATED WITH AMD  
The invention relates to genes, gene polymorphisms, and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD. The...
US20110046006 MEANS AND METHODS FOR TYPING A CELL ISOLATE OF AN INDIVIDUAL SUFFERING FROM A PSYCHIATRIC DISORDER OR AT RISK OF SUFFERING THERE FROM  
The present invention relates to a method for typing a cell isolate of an individual suffering from a pychiatric disorder, or at risk for suffering there from, the method comprising providing an...
US20110104679 Methods and Compositions for the Diagnosis and Treatment of Angiogenic Disorders  
The invention provides methods and compositions for determining whether an individual is at risk of developing, or has, one or more angiogenic disorders. The methods detect the presence and/or...
US20110081652 METHOD OF CLASSIFYING GENE EXPRESSION STRENGTH IN LUNG CANCER TISSUES  
The present invention provides a method of confirming the gene expression, useful in the decision of a five year survival rate of a patient with lung cancer and the use of a DNA probe kit in the...
US20110033842 Skin Sampling Kit Which Stores Nucleic Acids In Stable Status, Genetic Test Methods By Using The Kit And Their Practical Application  
The present invention relates to a new skin gene card for genetic test, a method for acquiring DNA and RNA and performing various genetic tests using the same, and practical applications thereof....
US20080268446 Flexible Culture Medium Bag Containing Nutrient Concentrate  
Disclosed is a culture medium container such as a bag comprising a main compartment and a locus of containment that contains a nutrient concentrate until it is released at the time of use. The...
US20110151445 ALLELIC DISORDERS CAUSED BY MUTATIONS IN TRPV4  
The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are...
US20110044894 Immunoglobulin and/or Toll-Like Receptor Proteins Associated with Myelogenous Haematological Proliferative Disorders and Uses Thereof  
The disclosure relates to methods and compositions effective in the diagnosis, prognosis and treatment of human hematopoietic cancers. In particular, the disclosure provides tumor-associated genes...
US20130317083 NON-CODING TRANSCRIPTS FOR DETERMINATION OF CELLULAR STATES  
Disclosed herein are novel methods, assays and systems for determining a given state of a cell or a tissue by detecting the presence or absence of a short RNA molecule originating from (a) at...
US20110003289 METHOD FOR DETECTION OF PRE-NEOPLASTIC FIELDS AS A CANCER BIOMARKER IN ULCERATIVE COLITIS  
Among other aspects, the present invention provides biomarkers and methods of identifying precancerous fields in a subject in need thereof. Methods of diagnosing and for providing a prognosis for...
US20110244470 ISOLATED TRANSGENIC MAMMALIAN NEURAL CELL FOR DETECTION OF A SAMPLE CONTAINING A CHEMICAL SUBSTANCE DAMAGE TO NEUROLOGICAL SYSTEM OR SELECTION OF DRUGS FOR TREATING NEURODEGENERATIVE DISORDERS  
The invention is to provide an isolated transgenic mammalian neural cell, which comprises at least one heterologous vector expressing AhR/ARNT. Also provided is methods the detection of a sample...
US20100297127 USE OF IL-27 ANTAGONISTS TO TREAT LUPUS  
This invention relates to methods of treating the autoimmune disorder lupus with IL-27 antagonists, as well as articles of manufacture comprising IL-27 antagonists. The invention also relates to...
US20110015259 TLE3 AS A MARKER FOR CHEMOTHERAPY  
Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer.
US20110070265 ENGINEERED PERTACTIN VARIANTS FOR VACCINE USE  
The present invention is related with the field of Biomedicine. It comprises the engineering of the Pertactin protein (Prn) and using it as part of bacterial vaccines, and more precisely, as part...
US20100330552 Comparative cellular deficiency diagnosis genetic deviation diagnosis procedure cellular protein output deficiency  
This procedure is intended to demonstrate the genetic foundation of infirmities caused by abnormal base pair sequences and protein deficiencies (which are an expression of genetic aberrations)....
US20110256150 Modulation of Axon Degeneration  
The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to...
US20100310532 GENE TARGETS IN ANTI-AGING THERAPY AND TISSUE REPAIR  
Novel gene and protein targets are described for treatment of cardiac disorders, anti-aging therapies and tissue repair. Identified biomarkers are prognostic of long term survival of patients...
US20100297648 METHOD FOR DIAGNOSING SUSCEPTIBILITY TO POST-TRAUMATIC SCAR-TISSUE FORMATION  
Disclosed is an in vitro method for diagnosing susceptibility to post-traumatic scar tissue formation, wherein from a biological sample of a patient the nucleotide of the -509 position of the...
US20110091439 COSMETIC USE OF ACID CERAMIDASE TYPE PROTEINS  
A method for preventing and/or treating the signs of skin aging comprises administering as an agent into an individual in need thereof an effective amount of acid ceramidase, polypeptides derived...
US20110027186 TAZ/WWTR1 FOR DIAGNOSIS AND TREATMENT OF CANCER  
We provide an anti-TAZ agent for the treatment, prophylaxis or alleviation of cancer. We further provide a kit for detecting breast cancer in an individual or susceptibility of the individual to...
US20110039708 MOLECULAR CLASSIFIER FOR PROGNOSIS IN MULTIPLE MYELOMA  
The invention relates to a 15-gene molecular classifier consisting of the following genes: CNDP2; STMN1; AFG3L2; STK38; PARP1; CPSF6; LOC151162; C20orf100; FRY; FLJ21438; MGST1; ALDH2; CTSF; ATF4;...
US20100316991 HUMAN PARAINFLUENZA VIRUS TYPE 3 EXPRESSING THE ENHANCED GREEN FLUORESCENT PROTEIN FOR USE IN HIGH-THROUGHPUT ANTIVIRAL ASSAYS  
Disclosed herein is a recombinant human parainfluenza virus expressing the enhanced green fluorescent protein. Methods of making and methods of using a recombinant human parainfluenza virus...
US20110117557 Methods and Compositions For Diagnosis of Age-Related Macular Degeneration  
The invention generally concerns methods and compositions for screening individuals for susceptibility to age-related macular degeneration (AMD). In particular, association with the various...
US20110086777 METHOD FOR AUTISM PREDICTION  
The present invention relates to a method for evaluating the level of risk for a subject to develop autism, or an autism spectrum disorder, which method comprises determining the number of risk...
US20100173302 POSITIVE CONTROL PROTEINS FOR GLUCOSE TRANSPORTER PROTEINS AND PROCESSES FOR THE GENERATION OF SUCH POSITIVE CONTROL PROTEINS  
Positive controls for experimentation related to membrane-bound glucose transporter proteins and methods for preparing such positive controls, such proteins including GLUT1, GLUT4, GLUT5, and GLUT12.
US20110033486 GENE EXPRESSION MARKERS FOR CROHN'S DISEASE  
The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of...
US20100317541 Method of Determining the Probability of a Therapeutic Response in Cancer Chemotherapy With Cardiac Glycoside  
A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment...
US20110251086 NEUROBLASTOMA PROGNOSTIC MULTIGENE EXPRESSION SIGNATURE  
The current invention relates to new tools and methods enabling neuroblastoma patient stratification into prognostic favorable or unfavorable groups. The invention is based on the re-analysis of...
US20050164208 Storage of genetic information  
Methods for the long-term storage of hereditary information such as DNA are described herein. In some instances, lyophilized DNA and sugar is introduced into a hermetically sealed vial. Kits for...
US20090269350 Novel 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 10A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3, NARC 4, NARC 7, NARC 8, NARC 11, NARC 14A, NARC 15, NARC 16, NARC 19, NARC 20, NARC 26, NARC 27, NARC 28, NARC 30, NARC 5, NARC 6, NARC 9, NARC 10C, NARC 8B, NARC 9, NARC2A, NARC 16B, NARC1C, NARC 1A, NARC 25, 86604 and 32222 molecules and uses therefor  
The invention provides isolated nucleic acids molecules and proteins, designated 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 20A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3,...
US20110117558 DIAGNOSIS OF HEREDITARY SPASTIC PARAPLEGIAS (HSP) BY IDENTIFICATION OF A MUTATION IN THE ZFYVE26 GENE OR PROTEIN  
The Invention relates to an ex vivo method of diagnosing or predicting a hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a mutation in the ZFYVE26 gene or...
US20130344066 METHODS OF MONITORING CONDITIONS BY SEQUENCE ANALYSIS  
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA...
US20090036415 Identification and treatment of estrogen responsive prostate tumors  
The present invention is directed to specific chromosomal rearrangements that are associated with prostate tumors that respond to compounds acting at estrogen receptors. Patients having the...
US20110009469 COMPOSITIONS AND METHODS OF TREATING NEOPLASIA  
The present invention provides compositions and methods featuring microRNA polynucleotides for the diagnosis, treatment or prevention of neoplasia.
US20130164217 METHOD OF DIAGNOSING, PREVENTING AND/OR TREATING DEMENTIA & RELATED DISORDERS  
Described are assay methods, modules and kits useful in the detection, treatment and/or prevention of dementia and related conditions, including but not limited to Alzheimer's disease and mild...
US20110004955 Transgenic plants with enhanced agronomic traits  
This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention...
US20100256014 NOVEL AS160-LIKE PROTEIN, TEST SYSTEMS, METHODS AND USES INVOLVING IT FOR THE IDENTIFICATION OF DIABETES TYPE 2 THERAPEUTICS  
The present invention relates to novel AKT substrate 160 kDa-like protein (AS160-like protein), to a method of identifying a substance altering glucose uptake and/or GLUT4 translocation to the...
US20110020808 BIOMARKERS FOR DIAGNOSING SCHIZOPHRENIA AND BIPOLAR DISORDER  
The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and...
US20110002893 DIAGNOSIS AND TREATMENT OF CONGENITAL HEART DEFECTS USING NELL1  
The present invention provides diagnostic methods for detecting congenital heart defects, or increased risk thereof, based on the Nell1 gene, RNA and protein. The methods include obtaining a...