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US20140273209 ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE  
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the...
US20110092949 IMMUNOISOLATION PATCH SYSTEM FOR CELLULAR TRANSPLANTATION  
An immunoisolation patch system, and particularly a patch system comprising multiple immunoisolation microcapsules, each encapsulating biological material such as cells for transplantation, which...
US20150210980 SYSTEM FOR IN-SITU MANAGEMENT OF pH OF CULTURE  
Disclosed is a hydrogel composition loaded with a base that regulates and maintains the pH of cell culture media. The invention particularly discloses in situ pH managing hydrogels (pHmH) loaded...
US20130190210 ENGINEERED TISSUES FOR IN VITRO RESEARCH USES, ARRAYS THEREOF, AND METHODS OF MAKING THE SAME  
Disclosed are living, three-dimensional tissue constructs for in vitro scientific and medical research, arrays thereof, and methods of making said tissues and arrays.
US20120183989 METHOD FOR CULTURE OF HEPATOCYTES  
A method for culturing hepatocytes, wherein hepatocytes embedded in an extracellular matrix is placed on a gas-permeable membrane and the hepatocytes are cultured while being supplied with oxygen...
US20110135707 POLYHYDROXYALKANOATES FOR IN VIVO APPLICATIONS  
Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or...
US20120058560 Bioreactor System  
Bioreactors may be used for the cultivation of cells, in particular of adherent cells, and, in particular for the cultivation and propagation of cell cultures, and utilized in methods for the...
US20120211373 MICROFLUIDIC SYSTEM FOR MEASURING CELL BARRIER FUNCTION  
The present invention relates to devices, systems and methods for measuring cell barrier function. In particular, the present invention relates to microfluidic devices for use in in vitro models...
US20110091930 WELL-BASED FLOW SYSTEM FOR CELL CULTURE  
A well-based flow system for cell culture is described which provides for flow of culture containing compounds for drug screening to be exposed to cells seeded on a membrane. The flow of medium...
US20140178997 SOFT TISSUE IMPLANTS AND METHODS FOR MAKING SAME  
The present invention features soft tissue implants and methods for making same. The implants can includes a biocompatible film that is rendered porous due to the inclusion of uniformly or...
US20110287470 CELL CULTURE METHOD TO FORM AGGREGATES  
The invention relates to the field of cell and tissue culture. In particular, the invention provides methods for culturing cells to form aggregates, including stem cells and primary cells. A...
US20100178698 TISSUE CULTURE DEVICE  
A tissue culture device includes a container having one or more upstanding walls extending upwardly from a floor. The floor of the container has a media having nutrients or growth substances...
US20110081721 PROCESS FOR PRODUCING A TISSUE TRANSPLANT CONSTRUCT FOR RECONSTRUCTING A HUMAN OR ANIMAL ORGAN  
A process for producing a tissue transplant construct for reconstructing a human or animal organ. The process may include the steps of: (a) isolation and two-dimensional cultivation of...
US20150118200 PRODUCTION OF EXTRACELLULAR MATRIX, CONDITIONED MEDIA AND USES THEREOF  
Provided is a matrix for promoting survival and differentiation of cells transplanted thereon, comprising a base matrix and a cell-made matrix thereon. Methods and means for making and using same...
US20150147810 ULTRATHIN PARYLENE-C SEMIPERMEABLE MEMBRANES FOR BIOMEDICAL APPLICATIONS  
Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be...
US20130143326 ULTRATHIN PARYLENE-C SEMIPERMEABLE MEMBRANES FOR BIOMEDICAL APPLICATIONS  
Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be...
US20110236464 MEMBRANE  
The invention relates to a membrane for supporting cells, especially RPE cells. The membrane is useful in the treatment of conditions such as age related macular degeneration.
US20120141430 Tissue Regeneration Membrane  
The present invention relates to a membrane comprising at least one positively charged, synthetic, hydrophobic polymer, at least one hydrophilic polymer and at least one plasticizer; wherein said...
US20120028275 BIOMIMETIC MEMBRANE FOR CELL EXPANSION  
The invention relates to a membrane which can be used for cultivating adherent or suspension cells, in particular adherent cells, wherein said membrane allows for the adhesion and proliferation of...
US20150024495 DEVICE AND METHOD FOR ENGINEERING LIVING TISSUES  
A device for assembling aggregations of adherent cells includes a gripper moveable within an assembly vessel that fixes aggregations of adherent cells at a membrane of the gripper and, by movement...
US20050015064 Skin cell perfusion unit  
This invention concerns a unit for skin cell perfusion for the culture-, preservation-, proliferation-, and utilization of skin cells, skin fibroblasts, skin progenitor cells in vitro, as well as...
US20110151565 CELL SHEET HAVING GOOD DIMENSIONAL STABILITY, METHOD FOR PRODUCTION THEREOF, AND CELL CULTURE CARRIER FOR USE IN THE METHOD  
It is an object of the present invention to provide a cell culture carrier for producing a cell sheet that can be readily detached from a cell culture carrier and is inhibited from contracting...
US20080145344 Three-dimensional tissue equivalent using macromass culture  
The present invention provides a three-dimensional tissue equivalent for in-vivo and in-vitro uses. The three dimensional tissue equivalent of the present invention is a non-contractile cellular...
US20140212974 CELL CULTURE MEMBRANE, CELL CULTURE SUBSTRATE, AND METHOD FOR MANUFACTURING CELL CULTURE SUBSTRATE  
Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and...
US20100136645 METHOD FOR PREPARING A CELL-DERIVED EXTRACELLULAR MATRIX SCAFFOLD  
The present invention relates to a method for fabricating a cell-derived extracellular matrix scaffold, more particularly, to a method for fabricating a cell-derived extracellular matrix scaffold,...
US20120034695 TISSUE/CELL CULTURING SYSTEM AND RELATED METHODS  
A system for culturing cells and/or tissue includes a tissue/cell culture chamber including a tissue/cell culture membrane, at least one collapsible valve fluidly coupled with the tissue/cell...
US20120145626 DEVICE FOR RENAL CELL EXPANSION  
A device for culturing, storing and expanding adherent renal cells. The device permits the adhesion and proliferation of the cells and the surface characteristics of the membrane material used in...
US20060252981 Biocompatible implant and use of the same  
The present invention provides an implant capable of being cellularized in treatment of an injured organ or tissue in organisms. The present inventors found that a biocompatible implant comprising...
US20130189671 Cell Culture System and Method of Use Thereof  
The present invention is based in part on the discovery of significant improvements to cell culture systems and methods in terms of utility and range of application. The system allows for culture...
US20130244328 METHOD OF CELL CULTURE  
This invention provides a means for modifying surface properties of a cell culture substrate under specific conditions, to thereby regulate regions to which cells are allowed to adhere or are not...
US20130236972 Liver Sinusoid Model  
A liver sinusoid model includes a generally planar substrate having first and second generally parallel microchannels formed therein. A microporous membrane is disposed between and separating the...
US20100035293 Pulsing of Bile Compartments in Sandwich-Cultured Hepatocytes  
A method of pulsing cultured hepatocytes, such as sandwich-cultured hepatocytes. The method includes providing a culture of hepatocytes, the culture having at least one bile canaliculus; exposing...
US20150093827 CELL CULTURE CARRIER AND CELL CULTURE VESSEL  
A cell culture carrier comprises an anodic oxide film having a plurality of micropores penetrating in a thickness direction from a front surface to a rear surface, wherein an average opening...
US20060240547 Linear and membrane-like biodevices and bioreactors  
A linear biodevice is provided with fibers that have a curved portion in its cross section approximately perpendicular to the longitudinal direction and approximately spherical adhesive cells that...
US20090074732 Scaffold for Cell Growth and Differentiation  
The present invention provides a devitalized mammalian parenchymatous tissue composition which includes an interstitial structure which can serve as a scaffold for tissue repair or regeneration....
US20100137203 METHOD FOR PREPARING A CELL-DERIVED EXTRACELLULAR MATRIX MEMBRANE  
The present invention relates to a method for preparing a cell-derived extracellular matrix membrane, more particularly, to a method for preparing a chondrocyte-derived ECM membrane, the method...
US20110263022 IRRADIATED MEMBRANE FOR CELL EXPANSION  
A membrane for cultivating adherent or suspension cells, in particular adherent cells. The membrane permits adhesion and proliferation of the cells due to the irradiation of the wet or dry...
US20050032205 In vitro cell culture employing a fibrin network in a flexible gas permeable container  
This invention relates to in vitro cell culture employing a fibrin network in a flexible gas permeable container. Specifically, the invention is directed to a cell culture container comprising a...
US20090104593 Preparation and Use of Basement Membrane Particles  
A method for supporting the in vitro growth of one or more eukaryotic cell type(s), the method comprising; seeding cells of said cell type(s) onto particles comprising basement membrane or a...
US20070298497 Method of Culturing Mesenchymal Stem Cells  
This invention is directed toward methods of expanding mesenchymal stem cells ex vivo.
US20150147809 CELL SEEDING DEVICE AND METHOD  
Described is a device comprising an anchor, a tray including a well adapted to receive the anchor, and a cover adapted to engage the tray and cover the well. The device may be used to form a...
US20100159597 CELL CULTURE MEMBRANE, CELL CULTURE KIT, POROUS MATERIAL, PRODUCTION METHOD FOR CELL CULTURE MEMBRANE AND PRODUCTION METHOD FOR POROUS MATERIAL  
To produce a cell culture membrane having biocompatibility utilizing DNA of natural resources and a cell culture kit, the cell culture membrane having DNA ionically-cross-linked with calcium ions...
US20090233362 Porous Scaffold, Method of Producing the Same and Method of Using the Porous Scaffold  
A porous scaffold having pores for seeding cells characterized in that, in the outer peripheral face of the porous main body having the pores for seeding cells, a porous membrane having pores...
US20090214622 Nanoporous Membrane and Method of Preparation Thereof  
A nanoporous membrane structure characterised in that it has a hexagonal array of tubes with a substantially uniform inter-pore distance between the tubes wherein the distance is within the range...
US20050125077 Viable tissue repair implants and methods of use  
Biocompatible tissue implants are provided for repairing a tissue injury or defect. The tissue implants comprise a biological tissue slice that serves as a source of viable cells capable of tissue...
US20150093826 CELL CULTURE CARRIER AND CELL CULTURE VESSEL  
A cell culture carrier comprises an anodic oxide film having a plurality of micropores penetrating the anodic oxide film in a thickness direction, wherein an average density of the plurality of...
US20130337565 Method and Apparatus for Patterning Cells  
The present invention is directed to tissue engineering and, more particularly, to devices and methods that are used to pattern or deposit cells to simulate a tissue type in two dimensions or in...
US20050256588 Decellularized tissue  
An objective of the present invention is to overcome a problem that there is an inverse relationship between the decellularization rate and the strength of tissue. This problem was solved by...
US20130260465 CULTURE SYSTEMS  
A microplate is provided herein having a plate body with at least one well formed therein, the well having a first open end, a second end, an aperture being formed in the second end, and a side...
US20110294215 CULTURE SYSTEMS  
A microplate is provided herein having a plate body with at least one well formed therein, the well having a first open end, a second end, an aperture being formed in the second end, and a side...

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