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US20080014589 Microfluidic devices and methods of use thereof  
The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of...
US20110195440 SYSTEMS AND METHODS FOR IDENTIFYING ALLERGIES  
Systems and methods for identifying allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially...
US20110195439 SYSTEMS AND METHODS FOR DETERMINING CARDIAC CONDITIONS  
Systems and methods for determining cardiac conditions. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to...
US20110195404 SYSTEMS AND METHODS FOR DETERMINING CALCIUM LEVELS  
Systems and methods for determining calcium levels. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially...
US20110195398 SYSTEMS AND METHODS FOR DETECTING INSULIN RESISTANCE BIOMARKERS  
Systems and methods for detecting insulin resistance biomarkers. At least one embodiment of a system of the present disclosure comprises a stabilizing agent useful to completely or substantially...
US20090233807 ASSAYS THAT USE THE T1R1 RECEPTOR POLYPEPTIDES TO SCREEN FOR T1R1-ASSOCIATED TASTE MODULATORS  
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in...
US20090226947 NON-INVASIVE ENZYME SCREEN FOR TISSUE REMODELLING-ASSOCIATED CONDITIONS  
Methods and kits for diagnosing the presence of and prognosing the appearance of tissue remodelling-associated conditions, involving the presence of enzyme complexes in a biological sample, are...
US20090098553 Urine gene expression ratios for detection of cancer  
This invention relates to methods for determining the presence of cancer in a subject based on the analysis of the expression levels of an under-expressed tumour marker (TM) and at least one other...
US20080261260 USE OF GELSOLIN TO TREAT INFECTIONS  
The invention relates to the use of gelsolin to treat infections and to monitor the treatment of infections. The invention also provides methods up-regulating interleukin expression and methods...
US20080176241 Mitigation of photodamage in analytical reactions  
Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage...
US20060240403 Tape magazine for a hand-held device  
The present invention concerns a tape magazine especially for a hand-held device for analysing a body fluid with a test tape that can be unwound from a storage unit and wound onto a waste unit...
US20060024659 Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same  
A novel method has led to the identification of novel mixed ester-amidates of PMPA for retroviral or hepadnaviral therapy, including compounds of structure (5a) having substituent groups as...
US20050186559 Abeta42 lowering agents  
The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an Aβ42 lowering agent to a mammal under conditions in which levels of...
US20120129150 PARTICLES EMBEDDED IN A POROUS SUBSTRATE FOR REMOVING TARGET ANALYTE FROM A SAMPLE  
The invention provides devices, test kits and methods for removing target agents from a sample. The device contains one or more porous matrices having pore sizes larger than 10 μm, and a plurality...
US20100291536 SAMPLE PROCESSING CASSETTE, SYSTEM, AND METHOD  
The present invention provides a method and device for collecting treating and analysis of biological or chemical material by introducing a source material into a specimen container, transferring...
US20100227309 METHOD FOR QUANTITATIVELY DETERMINING LDL CHOLESTEROLS  
A method for quantitatively determining LDL cholesterol, including the steps of adding to serum a surfactant selected from among polyoxyethylenealkylene phenyl ethers and polyoxyethylenealkylene...
US20090035794 METHOD FOR DETECTING, SCREENING, AND/OR MONITORING CANCER IN AN INDIVIDUAL  
The invention relates to a method for screening and/or detecting and/or monitoring a cancer in an individual, said method comprising determining a first parameter represented by the concentration...
US20080227124 Solid phases optimized for chemiluminescent detection  
Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing...
US20080113367 CLIP BASED SAMPLING OF SEED FOR THE REMOVAL OF SPECIFIC SEED TISSUE OR STRUCTURES FOR SEED ANALYSIS  
Apparatus, methods, and systems for useful sampling of seed, wherein viability is maintained, are disclosed. Seed from one generation in a plant advancement experiment is individually sampled by...
US20080103190 THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS  
Disclosed herein are compounds, pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as...
US20080020473 Use of HE4 and other biochemical markers for assessment of endometrial and uterine cancers  
The disclosure relates to use of the HE4/HE4a marker(s) to assess endometrial and uterine cancer in a patient. The disclosure also relates to using tumors marks for diagnosis, grading and staging...
US20070148634 CELLS HAVING A SPECTRAL SIGNATURE AND METHODS OF PREPARATIONS AND USE THEREOF  
Methods, compositions and articles of manufacture for encoding a cell with semiconductor nanocrystals and/or other fluorophors are provided. The encoded cells can be subjected to functional assays...
US20060147902 Yeast screens for treatment of human disease  
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are...
US20060141446 Substrates, devices, and methods for cellular assays  
The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved...
US20060046244 Automated seed sampler and methods of sampling, testing and bulking seeds  
An automated seed sampler includes a sampling station; a sampler for removing material from a seed in the sampling station; a seed conveyer for conveying the seed from the sampling station to a...
US20050202406 Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems  
The invention enables high-throughput screening of compounds in living systems to detect unanticipated or unintended biological actions. The invention also allows for screening, detection, and...
US20110217720 Compositions and Kits Pertaining to Analyte Determination  
This invention pertains to methods, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling...
US20110065085 NOVEL HEPARIN ENTITIES AND METHODS OF USE  
The present invention relates to immobilized biologically active entities that retain a significant biological activity following manipulation. The invention also comprises a medical substrate...
US20100216115 METHODS AND COMPOSITIONS FOR DIAGNOSTIC USE IN CANCER PATIENTS  
Disclosed herein are methods and compositions useful for identifying therapies likely to confer optimal clinical benefit for patients with cancer.
US20090068690 METHODS FOR IDENTIFYING PATIENTS WITH AN INCREASED LIKELIHOOD OF HAVING OVARIAN CANCER AND COMPOSITIONS THEREFOR  
Screening methods for identifying patients with an increased likelihood of having ovarian cancer are provided. The screening methods involve the detection of expression of a plurality of...
US20080044804 COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES  
The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target...
US20080029390 Hydrogel for an intravenous amperometric biosensor  
A hydrogel for an intravenous amperometric biosensor is formed on an electrode from a matrix of chitosan and a cross-linking agent, such as genipin to immobilize a reactive agent such as glucose...
US20080009609 Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor  
The invention provides isolated nucleic acids molecules which encode pyruvate decarboxylase enzymes having improved decarboxylase activity, substrate affinity, thermostability, and activity at...
US20070105089 Interactive transparent individual cells biochip processor  
An Interactive Transparent Individual Cells Biochip Processor (ITICBP) device is described, which is useful for assessing a single, individual living cell at identifiable location or assessing...
US20060073538 In-vitro diagnostic medical devices for determining saliva volume  
The invention relates to a method of collecting saliva from the oral cavity for detecting a test substance, comprising the steps of (a) cleaning the oral cavity, (b) stimulating saliva secretion...
US20050287519 Methods, compositions and compound assays for inhibiting amyloid-beta protein production  
A method for identifying compounds that inhibit amyloid-beta precursor protein processing in cells, comprising contacting a test compound with a KINASE polypeptide, or fragment thereof, and...
US20050196745 Guided deposition in spatial arrays  
An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which...
US20050191614 High-throughput formation, identification and analysis of diverse solid forms  
The invention concerns arrays of solid-forms of substances, such as compounds and rapid-screening methods therefor to identify solid-forms, particularly of pharmaceuticals, with enhanced...
US20050186556 Cell migration assay  
The present invention is directed to a modified cell migration assay allowing for improved identification and discrimination of chemokine receptor antagonists from non-specific blockers.
US20050053913 Reverse two-hybrid systems  
Disclosed are methods for identifying molecular interactions (e.g., protein/protein, protein/DNA, protein/RNA, or RNA/RNA interactions). All of the methods within the invention employ...
US20140302536 DIAGNOSIS OF PULMONARY AND/OR CARDIOVASCULAR DISEASE  
Described are methods and kits for determining the likelihood of the presence of cardiovascular disease (CVD) or pulmonary disease (PD) in a subject using ST2/Interleukin 1 Receptor Like 1...
US20110209227 METHODS FOR THE DIAGNOSIS AND TREATMENT OF BONE DISORDERS  
This invention pertains to chemometric methods for the analysis of chemical, biochemical, and biological data, for example, spectral data, for example, nuclear magnetic resonance (NMR) spectra,...
US20110064747 METHODS FOR TREATMENT OF A SARCOMA USING AN EPIMETABOLIC SHIFTER (COENZYME Q10)  
Methods and formulations for treating a sarcoma in humans using an epimetabolic shifter, such as Coenzyme Q10, a building block of CoQ10, a derivative of CoQ10, an analog of CoQ10, a metabolite of...
US20090068674 Method and device for preparing a sample of biological origin in order to determine at least one constituent contained therein  
The invention relates to a method of preparing an original sample (3) of biological origin with a view to detecting at least one component contained in it, whereby the original sample (3) is...
US20090036318 Class II Human Histone Deacteylases, and Uses Related Thereto  
The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II...
US20080249009 Lipoprotein-Regulating Medicaments  
Methods and pharmaceutical compositions useful for treating obesity-related disorders using ApM-1 and related proteins.
US20080241861 Biological materials and methods useful in the diagnosis and treatment of diseases  
The present invention relates to a method of making a β-form of a prion protein which preferably has more β-sheet than α-helix structure and is soluble in the absence of a denaturant and/or is...
US20070281329 Characterization of individual polymer molecules based on monomer-interface interactions  
The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the...
US20070015138 Methods for identifying agents and conditions that modulate neurogenesis  
Methods and tools for identifying agents and conditions that modulate neurogenesis are disclosed. The disclosure also relates to methods and tools for identifying populations of neural stem cells...
US20050074745 Metabolic phenotyping  
A method of generating models with which to characterise selected aspects of the metabolic phenotype of subjects without dosing a test substance to those subjects or with which to predict, without...