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US20080014589 |
Microfluidic devices and methods of use thereof
The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of... |
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US20110195440 |
SYSTEMS AND METHODS FOR IDENTIFYING ALLERGIES
Systems and methods for identifying allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially... |
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US20110195439 |
SYSTEMS AND METHODS FOR DETERMINING CARDIAC CONDITIONS
Systems and methods for determining cardiac conditions. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to... |
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US20110195404 |
SYSTEMS AND METHODS FOR DETERMINING CALCIUM LEVELS
Systems and methods for determining calcium levels. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially... |
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US20110195398 |
SYSTEMS AND METHODS FOR DETECTING INSULIN RESISTANCE BIOMARKERS
Systems and methods for detecting insulin resistance biomarkers. At least one embodiment of a system of the present disclosure comprises a stabilizing agent useful to completely or substantially... |
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US20090233807 |
ASSAYS THAT USE THE T1R1 RECEPTOR POLYPEPTIDES TO SCREEN FOR T1R1-ASSOCIATED TASTE MODULATORS
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in... |
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US20090226947 |
NON-INVASIVE ENZYME SCREEN FOR TISSUE REMODELLING-ASSOCIATED CONDITIONS
Methods and kits for diagnosing the presence of and prognosing the appearance of tissue remodelling-associated conditions, involving the presence of enzyme complexes in a biological sample, are... |
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US20090098553 |
Urine gene expression ratios for detection of cancer
This invention relates to methods for determining the presence of cancer in a subject based on the analysis of the expression levels of an under-expressed tumour marker (TM) and at least one other... |
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US20080261260 |
USE OF GELSOLIN TO TREAT INFECTIONS
The invention relates to the use of gelsolin to treat infections and to monitor the treatment of infections. The invention also provides methods up-regulating interleukin expression and methods... |
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US20080176241 |
Mitigation of photodamage in analytical reactions
Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage... |
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US20060240403 |
Tape magazine for a hand-held device
The present invention concerns a tape magazine especially for a hand-held device for analysing a body fluid with a test tape that can be unwound from a storage unit and wound onto a waste unit... |
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US20060024659 |
Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
A novel method has led to the identification of novel mixed ester-amidates of PMPA for retroviral or hepadnaviral therapy, including compounds of structure (5a) having substituent groups as... |
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US20050186559 |
Abeta42 lowering agents
The invention provides a method of preventing, delaying, or reversing the progression of Alzheimer's disease by administering an Aβ42 lowering agent to a mammal under conditions in which levels of... |
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US20120129150 |
PARTICLES EMBEDDED IN A POROUS SUBSTRATE FOR REMOVING TARGET ANALYTE FROM A SAMPLE
The invention provides devices, test kits and methods for removing target agents from a sample. The device contains one or more porous matrices having pore sizes larger than 10 μm, and a plurality... |
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US20100291536 |
SAMPLE PROCESSING CASSETTE, SYSTEM, AND METHOD
The present invention provides a method and device for collecting treating and analysis of biological or chemical material by introducing a source material into a specimen container, transferring... |
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US20100227309 |
METHOD FOR QUANTITATIVELY DETERMINING LDL CHOLESTEROLS
A method for quantitatively determining LDL cholesterol, including the steps of adding to serum a surfactant selected from among polyoxyethylenealkylene phenyl ethers and polyoxyethylenealkylene... |
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US20090035794 |
METHOD FOR DETECTING, SCREENING, AND/OR MONITORING CANCER IN AN INDIVIDUAL
The invention relates to a method for screening and/or detecting and/or monitoring a cancer in an individual, said method comprising determining a first parameter represented by the concentration... |
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US20080227124 |
Solid phases optimized for chemiluminescent detection
Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing... |
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US20080113367 |
CLIP BASED SAMPLING OF SEED FOR THE REMOVAL OF SPECIFIC SEED TISSUE OR STRUCTURES FOR SEED ANALYSIS
Apparatus, methods, and systems for useful sampling of seed, wherein viability is maintained, are disclosed. Seed from one generation in a plant advancement experiment is individually sampled by... |
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US20080103190 |
THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS
Disclosed herein are compounds, pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as... |
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US20080020473 |
Use of HE4 and other biochemical markers for assessment of endometrial and uterine cancers
The disclosure relates to use of the HE4/HE4a marker(s) to assess endometrial and uterine cancer in a patient. The disclosure also relates to using tumors marks for diagnosis, grading and staging... |
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US20070148634 |
CELLS HAVING A SPECTRAL SIGNATURE AND METHODS OF PREPARATIONS AND USE THEREOF
Methods, compositions and articles of manufacture for encoding a cell with semiconductor nanocrystals and/or other fluorophors are provided. The encoded cells can be subjected to functional assays... |
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US20060147902 |
Yeast screens for treatment of human disease
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are... |
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US20060141446 |
Substrates, devices, and methods for cellular assays
The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved... |
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US20060046244 |
Automated seed sampler and methods of sampling, testing and bulking seeds
An automated seed sampler includes a sampling station; a sampler for removing material from a seed in the sampling station; a seed conveyer for conveying the seed from the sampling station to a... |
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US20050202406 |
Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
The invention enables high-throughput screening of compounds in living systems to detect unanticipated or unintended biological actions. The invention also allows for screening, detection, and... |
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US20110217720 |
Compositions and Kits Pertaining to Analyte Determination
This invention pertains to methods, kits and/or compositions for the determination of analytes by mass analysis using unique labeling reagents or sets of unique labeling reagents. The labeling... |
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US20110065085 |
NOVEL HEPARIN ENTITIES AND METHODS OF USE
The present invention relates to immobilized biologically active entities that retain a significant biological activity following manipulation. The invention also comprises a medical substrate... |
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US20100216115 |
METHODS AND COMPOSITIONS FOR DIAGNOSTIC USE IN CANCER PATIENTS
Disclosed herein are methods and compositions useful for identifying therapies likely to confer optimal clinical benefit for patients with cancer. |
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US20090068690 |
METHODS FOR IDENTIFYING PATIENTS WITH AN INCREASED LIKELIHOOD OF HAVING OVARIAN CANCER AND COMPOSITIONS THEREFOR
Screening methods for identifying patients with an increased likelihood of having ovarian cancer are provided. The screening methods involve the detection of expression of a plurality of... |
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US20080044804 |
COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES
The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target... |
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US20080029390 |
Hydrogel for an intravenous amperometric biosensor
A hydrogel for an intravenous amperometric biosensor is formed on an electrode from a matrix of chitosan and a cross-linking agent, such as genipin to immobilize a reactive agent such as glucose... |
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US20080009609 |
Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor
The invention provides isolated nucleic acids molecules which encode pyruvate decarboxylase enzymes having improved decarboxylase activity, substrate affinity, thermostability, and activity at... |
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US20070105089 |
Interactive transparent individual cells biochip processor
An Interactive Transparent Individual Cells Biochip Processor (ITICBP) device is described, which is useful for assessing a single, individual living cell at identifiable location or assessing... |
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US20060073538 |
In-vitro diagnostic medical devices for determining saliva volume
The invention relates to a method of collecting saliva from the oral cavity for detecting a test substance, comprising the steps of (a) cleaning the oral cavity, (b) stimulating saliva secretion... |
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US20050287519 |
Methods, compositions and compound assays for inhibiting amyloid-beta protein production
A method for identifying compounds that inhibit amyloid-beta precursor protein processing in cells, comprising contacting a test compound with a KINASE polypeptide, or fragment thereof, and... |
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US20050196745 |
Guided deposition in spatial arrays
An apparatus and method is provided for preparing and using a very large and diverse array of compounds on a substrate having rapidly accessible locations. The substrate contains cells in which... |
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US20050191614 |
High-throughput formation, identification and analysis of diverse solid forms
The invention concerns arrays of solid-forms of substances, such as compounds and rapid-screening methods therefor to identify solid-forms, particularly of pharmaceuticals, with enhanced... |
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US20050186556 |
Cell migration assay
The present invention is directed to a modified cell migration assay allowing for improved identification and discrimination of chemokine receptor antagonists from non-specific blockers. |
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US20050053913 |
Reverse two-hybrid systems
Disclosed are methods for identifying molecular interactions (e.g., protein/protein, protein/DNA, protein/RNA, or RNA/RNA interactions). All of the methods within the invention employ... |
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US20140302536 |
DIAGNOSIS OF PULMONARY AND/OR CARDIOVASCULAR DISEASE
Described are methods and kits for determining the likelihood of the presence of cardiovascular disease (CVD) or pulmonary disease (PD) in a subject using ST2/Interleukin 1 Receptor Like 1... |
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US20110209227 |
METHODS FOR THE DIAGNOSIS AND TREATMENT OF BONE DISORDERS
This invention pertains to chemometric methods for the analysis of chemical, biochemical, and biological data, for example, spectral data, for example, nuclear magnetic resonance (NMR) spectra,... |
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US20110064747 |
METHODS FOR TREATMENT OF A SARCOMA USING AN EPIMETABOLIC SHIFTER (COENZYME Q10)
Methods and formulations for treating a sarcoma in humans using an epimetabolic shifter, such as Coenzyme Q10, a building block of CoQ10, a derivative of CoQ10, an analog of CoQ10, a metabolite of... |
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US20090068674 |
Method and device for preparing a sample of biological origin in order to determine at least one constituent contained therein
The invention relates to a method of preparing an original sample (3) of biological origin with a view to detecting at least one component contained in it, whereby the original sample (3) is... |
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US20090036318 |
Class II Human Histone Deacteylases, and Uses Related Thereto
The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II... |
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US20080249009 |
Lipoprotein-Regulating Medicaments
Methods and pharmaceutical compositions useful for treating obesity-related disorders using ApM-1 and related proteins. |
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US20080241861 |
Biological materials and methods useful in the diagnosis and treatment of diseases
The present invention relates to a method of making a β-form of a prion protein which preferably has more β-sheet than α-helix structure and is soluble in the absence of a denaturant and/or is... |
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US20070281329 |
Characterization of individual polymer molecules based on monomer-interface interactions
The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the... |
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US20070015138 |
Methods for identifying agents and conditions that modulate neurogenesis
Methods and tools for identifying agents and conditions that modulate neurogenesis are disclosed. The disclosure also relates to methods and tools for identifying populations of neural stem cells... |
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US20050074745 |
Metabolic phenotyping
A method of generating models with which to characterise selected aspects of the metabolic phenotype of subjects without dosing a test substance to those subjects or with which to predict, without... |