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US20140106390 |
BIOMARKERS FOR THE TREATMENT OF MULTIPLE MYELOMA
Provided herein are the biomarkers for predicting or monitoring the efficacy of a treatment for multiple myeloma. The use of certain M-protein or other protein levels as biomarkers to predict... |
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US20130005608 |
YEAST SCREENS FOR TREATMENT OF HUMAN DISEASE
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are... |
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US20110300533 |
Yeast Screens for Treatment of Human Disease
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are... |
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US20110045477 |
HUMAN SKIN EXPLANT CULTURE SYSTEM AND USE THEREFOR
The present invention features a human skin explant culture system and uses thereof. |
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US20150132737 |
SYSTEM FOR KEEPING ALIVE AND TRANSPORTING SKIN BIOPSIES AND APPLICATIONS OF SAID SYSTEM
Disclosed is an in vitro or ex vivo method for preserving and/or keeping alive mammalian, preferably human skin biopsies, enabling to transport it and, if applicable, to culture it. Also disclosed... |
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US20140206008 |
Salivary Protein Biomarkers for Human Oral Cancer
The present invention relates to the identification of novel oral cancer and periodontal disease biomarkers. Further, the present invention provides novel methods of diagnosing and for providing a... |
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US20120009604 |
USE OF GRF1 PROTEIN FOR SCREENING MOLECULES
The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating... |
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US20140162305 |
Patient In Vivo Gut Diagnostic and Treatment Tool
An orally ingestible capsule device with monitoring and control instruments is provided for practicing physicians to use in patient examining rooms. The Capsule is part of an in vivo gut... |
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US20130017566 |
METHOD FOR ASSESSING THE CONDITION OF SKIN AND/OR SCALP
Method for assessing condition of skin and/or scalp by resulted color from the interaction of protein detecting composition with skin and/or scalp sample. Also disclosed is a method for comparing... |
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US20130012581 |
TREATMENT OF HEAD LICE INFESTATIONS
Techniques and apparatus for treating head lice infestations are described. Some embodiments include a nit (louse egg) detection plate that provides a surface against which irregularities of a... |
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US20100297632 |
UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the... |
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US20110027817 |
TAU PROTEIN SCREENING ASSAY
This invention is directed to methods for determining if a test compound can ameliorate tau protein induced reduction of long term potentiation in a neural structure. The invention is also... |
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US20130078656 |
ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the... |
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US20120282643 |
CYAN AND YELLOW FLUORESCENT COLOR VARIANTS OF SPLIT GFP
Disclosed herein are Split-Fluorescent proteins (SFPs) including Split-Yellow Fluorescent Proteins and Split-Cyan Fluorescent proteins. Further disclosed are methods of using SFPs. For example,... |
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US20110045475 |
UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER
The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the... |
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US20110300206 |
VACCINES AGAINST CHLAMYDIAL INFECTION
The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the... |
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US20110047633 |
Control of Exocrine Pancreatic Function Using Bone Morphogenetic Proteins
Methods are described for controlling exocrine pancreatic function, for reducing the level of amylase in the blood, and for treating pancreatitis in an individual comprising administering to the... |
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US20110006221 |
METHOD FOR EVALUATING OIL-AND-FAT AMOUNT IN SEED AND METHOD FOR SCREENING FOR PLANT EXHIBITING VARIED LEVEL OF OIL-AND-FAT CONTENT
This invention is intended to evaluate the oil-and-fat amount in a seed and genetic changes thereof. A fusion protein of an oil body-specific protein, such as the oleosin-GFP fusion protein, and a... |
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US20130078222 |
Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof
Provided are intervertebral disk nucleus pulposus stem cells or progenitor cells that may be used for treatment of intervertebral disk disorders. An intervertebral disk nucleus pulposus cell is... |
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US20150086993 |
MICROFLUIDIC THREE-DIMENSIONAL OSTEOCYTE NETWORK RECONSTRUCTED WITH MICROBEADS AS SCAFFOLD
A bed of microbeads is used as a foundation for reconstructing a three-dimensional osteocyte network by culturing osteocytes within the bed. The osteocytes are cultured such that they form a... |
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US20140341864 |
METHODS FOR PRODUCING RETINAL TISSUE AND RETINA-RELATED CELL
The invention provides a method for producing a retinal tissue by (1) subjecting pluripotent stem cells to floating culture in a serum-free medium containing a substance inhibiting the Wnt signal... |
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US20100298348 |
Method of Decreasing Ubiquitylated Protein Levels
The present invention provides a method of decreasing the level of ubiquitylated protein in a subject, the method comprising administering a heterocyclic compound disclosed herein or a... |
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US20120108464 |
TEST SYSTEMS, METHODS AND USES INVOLVING AS160 PROTEIN
The present invention relates to a method of identifying a substance altering glucose uptake and/or GLUT4 translocation to the plasma membrane of a cell comprising contacting a test system... |
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US20140173777 |
METHODS FOR ELEVATING FAT/OIL CONTENT IN PLANTS
In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algae cells, plant tissues, or whole plants by genetically modifying the... |
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US20110105343 |
Systems Biology Approach Predicts Immunogenicity of Vaccines
A major challenge in vaccinology is to prospectively determine vaccine efficacy. Disclosed herein are methods and compositions for identifying early expression “signatures” that predicted immune... |
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US20120009610 |
ENDOSTATIN AS A MARKER OF HEART FAILURE
Disclosed is a method for assessing heart failure in an individual including the steps of a) measuring in a sample obtained from the individual the concentration of the marker endostatin, of b)... |
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US20140073604 |
Ladder-Frame Polyether Conjugates
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and... |
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US20120077778 |
Ladder-Frame Polyether Conjugates
Disclosed are compounds that are conjugates of ladder frame polyether compounds and biologically active compounds or research compounds, pharmaceutical formulations comprising the conjugates, and... |
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US20110236921 |
CELL SYSTEM
The present invention relates to cellular systems for testing drug candidates and for evaluating the function of mitochondrial proteins. The invention is particularly useful for evaluating drug... |
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US20100168006 |
IN-PLANT PRODUCTION OF DIMERIC AND/OR OLIGOMERIC (COMPRISING THREE OR MORE UNITS) FORMS OF HUMAN APO A-1 PROTEIN MUTEINS
The present invention encompasses a method for the production of Apolipoproteins in dimeric and/or oligomeric forms (comprising three or more units) of muteins of the human ApoA-1 protein in plant... |
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US20120135435 |
Methods for Identifying Factors That Control the Folding of Amyloid Proteins of Diverse Origin
The present invention provides a yeast cell based system for determining factors that control the folding of amyloid proteins of diverse origins. Further the present invention provides methods of... |
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US20120141552 |
ULTRASOUND TECHNOLOGY TO CONTROL THE SPATIAL ORGANIZATION OF CELLS AND PROTEINS IN ENGINEERED TISSUES
The present invention is directed to methods of inducing spatial organization of cells an in vitro culture system using ultrasound technology. The invention is further directed to methods of... |
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US20110053198 |
UBIQUITIN PROTEASOME SYSTEM PROFILING AND THE USE THEREOF IN CLINICAL APPLICATIONS FOR PROLIFERATIVE HEMATOLOGICAL DISORDERS
Provided herein are methods for the diagnosis, prognosis, or management of proliferative hematological disorders and other diseases using profiles of the ubiquitin-proteasome system determined... |
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US20120003243 |
YEAST ECTOPICALLY EXPRESSING ABNORMALLY PROCESSED PROTEINS AND USES THEREFOR
Disclosed are yeast ectopically expressing abnormally processed proteins and methods of screening to identify compounds that modulate the function of such abnormally processed proteins in yeast.... |
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US20130045274 |
BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITIS
This document discusses, among other things, receiving a plurality of donor fecal samples from a plurality of donors and storing and indexing each respective donor fecal samples using at least one... |
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US20110212464 |
PACAP AS A MARKER FOR CANCER
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the proapoptotic caspase adaptor protein (=PACAP) as a universal marker of different types of... |
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US20110257035 |
IDENTIFICATION OF SIGNATURE GENES ASSOCIATED WITH HEPATOCELLULAR CARCINOMA
The present invention relates to, for example, (1) a novel method for identification of clinically useful serum and/or tumor biomarkers and expression signatures that can be used for detection,... |
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US20150190363 |
METHODS TO TREAT NEURODEGENERATIVE DISEASES
The present invention is based on the discovery that motor neurons derived from patients with a neuro-degenerative disease have decreased delayed rectifier potassium current and increased... |
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US20100304419 |
METHOD FOR DETERMINING THE PROGNOSIS OF GASTRIC CANCER
The 14-3-3β protein is used herein as a tumor marker for prognosis in gastric cancer. The method comprises steps of providing a biological sample, qualifying the 14-3-3β protein level in the... |
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US20140024010 |
METHOD FOR PRODUCING ARTIFICIAL SKIN MODEL, AND ARTIFICIAL SKIN MODEL
Provided is a novel method capable of producing an artificial skin model. A method for producing an artificial skin model includes: providing coated cells (1), each of which is obtained by... |
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US20150071857 |
STEROID HORMONE AND CHOLESTEROL PATHWAYS AS ONE UNIFIED HOMEOSTATIC SYSTEM
A unified homeostatic system of cholesterol and steroid hormone pathways is described, in which the uses or modulations of function of the homeostatic system of cholesterol and steroid hormone... |
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US20110071123 |
Noninvasive Method for Measuring Histamine From Skin as an Objective Measurement of Itch
A method for measuring of histamine in an epidermis comprising applying an adhesive article to an epithelium of a mammal; allowing for adherence of epithelial cells to the adhesive article;... |
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US20100311099 |
USE OF HE4 FOR ASSESSMENT OF BREAST CANCERS
The disclosure relates to use of the HE4 marker to assess breast cancer in a patient. The disclosure also relates to using HE4 and other tumors markers for diagnosis, grading and staging of breast... |
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US20110313233 |
DOWN-REGULATION OF COLD SHOCK PROTEINS FOR CANCER TREATMENT
The present invention is in the field of treatment of diseased tissues, including cancerous tissues. In one embodiment, the present invention provides methods of identifying tissues that... |
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US20150018966 |
DECELLULARISATION OF TISSUE MATRICES FOR BLADDER IMPLANTATION
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is... |
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US20110086796 |
METHODS FOR PREDICTING THE DEVELOPMENT AND RESOLUTION OF ACUTE RESPIRATORY DISTRESS SYNDROME
The subject invention features methods for predicting whether a subject at risk of developing Acute Respiratory Distress Syndrome (ARDS) will develop ARDS by determining the amount of elafin... |
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US20120064565 |
System Setup For Biological Methane Potential Test
A system setup is disclosed for carrying out a biological methane potential test on a biosample and a system setup is disclosed for measuring biomethane gas in a biogas flow. In at least one... |
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US20140335532 |
HUMAN SKIN SAMPLE METHODS AND MODELS FOR VALIDATING HYPOTHESES FOR MECHANISMS DRIVING SKIN PIGMENTATION
Human skin tissue sample methods and models for validating hypotheses for mechanisms driving skin pigmentation as well as methods for driving skin pigment levels in ex-vivo skin tissue. The method... |
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US20110070603 |
DISC FOR TESTING BLOOD, BLOOD TESTER HAVING THE SAME, AND CONTROL METHOD THEREOF
Disclosed are a blood tester for measurement of temperature of a sample placed in a blood-testing disc using a thermochromic pigment, and a control method thereof. The disclosed blood-testing... |
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US20110212483 |
Methods and Kits for the Diagnosis of RyR1-Related Diseases
The present invention encompasses methods for diagnosis of calcium channel related diseases (e.g., RyR1-related diseases) comprising contacting lymphocytes isolated from a subject with a calcium... |