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US20120021470 Chimeric PUFA Polyketide Synthase Systems and Uses Thereof  
Disclosed are chimeric polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) proteins and chimeric PUFA PKS systems, including chimeric PUFA PKS proteins and systems derived from...
US20110179503 PROTEIN PRODUCTION IN A HOST  
Recombinant DNA constructs that provide for expression of desired target proteins as protein bodies in various host cells, tissues, and organisms are disclosed. Such recombinant DNA constructs...
US20120282643 CYAN AND YELLOW FLUORESCENT COLOR VARIANTS OF SPLIT GFP  
Disclosed herein are Split-Fluorescent proteins (SFPs) including Split-Yellow Fluorescent Proteins and Split-Cyan Fluorescent proteins. Further disclosed are methods of using SFPs. For example,...
US20110189218 Plasmodium vivax hybrid circumsporozoite protein and vaccine  
Described in this application is a synthetic P. vivax circumsporozoite protein useful as a diagnostic reagent, for antibody production, and as a vaccine protective against infection with any...
US20100303849 Lipidated Vaccine against Dengue Virus Infection  
Disclosed are immunogenic composition, fusion proteins, and related methods for inducing immune response to dengue virus infection.
US20110152171 HISTAMINE BINDING PROTEIN  
The invention relates to histamine binding proteins. The invention also relates to the use of such histamine binding proteins in the treatment and prevention of diseases.
US20140128287 SYSTEMS FOR INDUCTION OF GENE EXPRESSION AND PROTEIN DEPLETION IN YEAST  
A system allows for rapid and specific induction of individual genes in eukaryotic cells using a chimeric transcriptional activator that is responsive to hormone inducer. Upon addition of the...
US20110126455 METHOD FOR PRODUCTION OF INOCULUM OF MICROORGANISMS OPTIMIZED AS CATALYST FOR MULTIPLE PARALLEL MINERALIZATION  
Provided is a method of producing an inoculum, which can drastically reduce a time to complete a reaction for mineralizing an organic material into nitrate nitrogen and can add a large amount of...
US20110206724 HEPATITIS VIRUS CORE PROTEINS AS VACCINE PLATFORMS AND METHODS OF USE THEREOF  
The present invention relates to hepatitis virus core proteins and nucleic acids. In particular, the present invention provides compositions and methods comprising recombinant hepatitis virus core...
US20120203714 Systems for Growing Phototrophic Organisms Using Green Energy  
A system for producing phototrophic biomass is provided. The system includes a green power generator and a carbon sequestering system. The green power generator is provided for generating power,...
US20110159514 BIOMARKER FOR OSTEOARTHRITIS AND/OR OTHER AGEING-RELATED DISEASES, AND USE THEREOF  
The invention relates to the identification of a biomarker whose abundance in biological sample is changed in subjects with osteoarthritis and/or other ageing-related diseases. The biomarker has...
US20110268790 Snake Factor V and Methods of Use Thereof as a Procoagulant  
Compositions and Methods for the treatment of coagulation disorders using Factor V variants are provided. Preferred disorders include hemophilia A and B.
US20110045554 HETEROLOGOUS EXPRESSION OF EXTREMOPHILE HEAT SHOCK PROTEINS AND CHAPERONES IN MICROORGANISMS TO INCREASE TOLERANCE TO TOXIC COMPOUNDS  
The invention provides methods and compositions for increasing tolerance of microorganisms to toxic agents, such as solvents; and for increasing production of solvents from solvent-generating...
US20110160175 18,21-Didesoxymacbecin Derivatives for the Treatment of Cancer  
The present invention relates to macbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and...
US20130224837 INOCULATION TOOL AND METHOD OF USE THEREOF  
The present invention describes disposable inoculation tools designed to fit into an appropriately sized test tube with the lid closed. A method that reduces the overall number of steps required...
US20110256605 CELLS WITH NON-NATURAL PHYSIOLOGIES DERIVED BY EXPRESSING LIGHT-POWERED PROTON PUMPS IN ONE OR MORE MEMBRANES  
Methods and procedures for designing and constructing microbes with the ability to harvest light energy are described. In certain embodiments, these methods and procedures are used to construct a...
US20100317086 LARGE SCALE MICROBIAL CULTURE METHOD  
A new culture method for producing high levels of a metabolite, such as succinic acid uses oxygen rich culture without pH adjustment to increase the biomass, acclimation in under oxygen lean...
US20110171218 COMPOSITIONS AND METHODS FOR INCREASING SERUM HALF-LIFE  
Provided herein are glycovariant Fc fusion proteins having increased serum half lives. Also provided are methods for increasing the serum half life of an Fc fusion protein by introducing one or...
US20130263330 Methods for Production of Synthetic Promoters with Defined Specificity  
The present invention relates to methods for the design and production of synthetic promoters with a defined specificity and promoters produced with these methods.
US20110207801 Novel Genes, Compositions, and Methods for Modulating the Unfolded Protein Response  
The present invention relates to methods and compositions for modulating the unfolded protein response. The method further relates to methods and compositions for the treatment and diagnosis of...
US20110207656 MUC1, CASPASE-8, and DED-CONTAINING PROTEINS  
The disclosure features a variety of compositions and methods for modulating an interaction between MUC1 and caspase-8 and/or an interaction between MUC1 and a DED-containing protein (e.g., an...
US20130090345 Synthetic Mimetics Of Host Defense And Uses Thereof  
The present invention provides arylamide compounds and methods of making and using them as antibiotics.
US20110003333 Method for Increasing Expression Yield of a Protein of Interest  
The present invention relates to a method of producing a protein of interest comprising: (a) cultivating a mutant cell under conditions conducive for production of the protein wherein the mutant...
US20110207124 Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism  
Compositions and methods for the detection and treatment of autism and autistic spectrum disorder are provided.
US20110305634 Methods and systems for adenovirus interaction with desmoglein 2 (DSG2)  
The present invention provides compositions and methods for treating disorders associated with epithelial tissues.
US20110183377 METHODS, SYSTEMS AND REAGENTS FOR IMPROVED IMMUNODETECTION  
The instant invention provides methods, systems and reagents for immunodetection involving novel epitope tags and antibodies which recognize these new epitope tags as well as the antibodies which...
US20110269688 Genetic Alterations Associated with Schizophrenia and Methods of Use Thereof for the Diagnosis and Treatment of the Same  
Compositions and methods for the detection and treatment of schizophrenia are provided.
US20120022232 CELLS FOR INCREASED PROTEIN EXPRESSION COMPRISING ONE OR MORE RELEASE FACTORS AND METHODS OF USE  
The invention provides recombinant cells or recombinant restrictive cells for overexpressing one or more proteins comprising one or more release factors. The invention also provides methods for...
US20110081705 RECOMBINANT ELASTASE PROTEINS AND METHODS OF MANUFACTURING AND USE THEREOF  
The present invention relates to methods for the manufacture, purification, formulation, and use of biologically active recombinant elastase proteins. Described are recombinant methods for...
US20110033897 Method for the Obtainment of Hydrolytic Enzymes, Hydrolytic Method for Producing Fermentable Sugars, Additives comprising Fermentable Sugars, and Process for Producing Ethanol from Sugar Cane Bagasse  
The present invention provides industrial methods involving the hydrolysis of sugar cane bagasse, including methods for producing hydrolytic enzymes, for hydrolysis of sugar cane bagasse, for the...
US20110027845 ENHANCED ETHANOL AND BUTANOL PRODUCING MICROORGANISMS AND METHOD FOR PREPARING ETHANOL AND BUTANOL USING THE SAME  
The present invention relates to a recombinant microorganism having an enhanced ability to produce ethanol and butanol and a method for preparing ethanol and butanol using the same, and more...
US20110195074 Ephrin Type-A Receptor 7 Protein  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, gastric cancer, head and neck cancer,...
US20110070625 NOVEL FLUORESCENT PROTEINS AND METHODS FOR USING SAME  
The present invention provides nucleic acid molecules encoding novel red fluorescent proteins from Entacmaea quadricolor and mutants thereof. Also of interest are proteins that are substantially...
US20150166634 Soluble TNF Receptors and Their Use in Treatment of Disease  
The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of...
US20100313309 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS  
Disclosed are novel acyl-CoA synthetases and novel acyltransferases, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic...
US20150159147 Compositions And Methods Comprising Variant Microbial Proteases  
The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In...
US20110256609 Compositions And Methods Comprising Variant Microbial Proteases  
The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In...
US20110212838 Sulfonylurea-Responsive Repressor Proteins  
Compositions and methods relating to the use of sulfonylurea-responsive repressors are provided. Compositions include polypeptides that specifically bind to an operator, wherein the specific...
US20130096332 METHOD FOR INCREASING THE CONTENT OF DOCOSAHEXAENOIC ACID IN FAT-CONTAINING MATERIALS OR IN FATS AND OILS  
To provide a fat-and-oil in which the content of docosahexaenoic acid is increased. A process for producing highly unsaturated fatty acids comprising culturing a stramenopile capable of producing...
US20150141616 Disulfide Stabilized Foldon Polypeptides  
Intermolecular disulfide stabilized foldon polypeptides are provided.
US20120054910 Antipathogenic Proteins and Methods of Use  
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for...
US20120028801 Corn Steep Liquor as A Biostimulant Composition  
Aspects of the invention relate to organic biostimulant compositions, including, for example, formulations comprising corn steep liquor (CSL) and water. In certain illustrative embodiments, the...
US20110209250 METHODS AND COMPOSITIONS FOR PLANT IMPROVEMENT  
The invention provides an isolated polynucleotide comprising the sequence of SEQ ID NO: 1 or a variant thereof, wherein the variant encodes a polypeptide capable of modulating in a plant tolerance...
US20110256180 Factor H Binding Proteins (FHBP) with Altered Properties and Methods of Use Thereof  
Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
US20110244575 METHODS, SYSTEMS AND COMPOSITIONS FOR INCREASED MICROORGANISM TOLERANCE TO AND PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP)  
The present invention relates to methods, systems and compositions, including genetically modified microorganisms, adapted to exhibit increased tolerance to 3-hydroxypropionic acid (3-HP),...
US20110091933 METHOD OF TREATING MICROORGANISM  
A method of treating microorganisms which can solve conventional problems in a treatment of counting the number of microorganisms, a proliferation treatment of microorganisms and a purification...
US20110135606 TEST SYSTEMS FOR THE ANALYSIS OF POLYPEPTIDES AND CELLS ADHERING TO SILICONES  
The present invention relates in general to the field of diagnostics, namely to test systems for polypeptides in respect to silicone. More precisely, the present invention, in one embodiment...
US20110009308 Subtilase Variants Having Altered Immunogenicity  
The present invention relates to subtilase subtilases with an altered immunogenicity, particularly subtilases with a reduced allergenicity. Furthermore, the invention relates to expression of said...
US20110142869 MEMBRANE PROXIMAL REGION OF HIV GP41 ANCHORED TO THE LIPID LAYER OF A VIRUS-LIKE PARTICLE VACCINE  
Disclosed herein are isolated immunogens including variant hepatitis B surface antigens (HBsAgs). In an example, a variant HBsAg includes a HBsAg with one or more transmembrane domains of the...
US20110171266 MALARIA VACCINE  
The present invention features immunogenic compositions based on pre-fertilization or post-fertilization antigens expressed in the circulating gametocytes in the peripheral blood of infected...