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US20130071429 BUNYAVIRUS VACCINE  
The present invention provides attenuated viruses for use as vaccines and for the treatment and/or prevention of viral diseases and/or infections.
US20120177675 Chimaeric Protein  
The present invention provides a chimaeric coronavirus S protein which is based on an S protein from a coronavirus strain with restricted tissue tropism, but which comprises at least part of the...
US20120232133 DELIVERY OF PROTEINS USING ADENO-ASSOCIATED VIRUS (AAV) VECTORS  
Disclosed herein are compositions, systems and methods for delivery of proteins of interest using adeno-associated virus (AAV) vectors.
US20140178430 IDNA VACCINES AND METHODS FOR USING THE SAME  
Described herein are iDNA vectors and vaccines and methods for using the same. The iDNA generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses,...
US20130115234 Ectodomains of Influenza Matrix 2 Protein, Expression System, and Uses Thereof  
The present invention provides a polynucleotide, polypeptide, recombinant modified vaccinia virus Ankara (rMVA) and related vaccine compositions and methods useful in the prevention and treatment...
US20100330650 RECOMBINANT VACCINE AGAINST JAPANESE ENCEPHALITIS VIRUS [JEV] INFECTION AND A METHOD THEREOF  
The present invention relates to a method for preparing recombinant adenovirus (RadEs) vaccine to protect against JEV infection. The vaccine produces secretory envelop protein (ES) of JEV.
US20120201852 Vaccines Against Japanese Encephalitis Virus and West Nile Virus  
The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
US20140030291 INFLUENZA VIRUS REASSORTMENT  
New influenza donor strains for the production of reassortant influenza A viruses are provided.
US20110124086 Hepatitis C Virus Culture System  
This disclosure provides compositions and methods for producing infectious hepatitis C virus (HCV). The produced HCV can be infectious in vivo and in vitro. In one aspect, the disclosure provides...
US20150010593 METHODS AND CELLS FOR THE PRODUCTION OF VIRAL VACCINES  
The present invention provides genetically modified cells useful for viral replication and the production of viral vaccines.
US20150166966 REVERSE GENETICS METHODS FOR VIRUS RESCUE  
A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
US20130034582 REVERSE GENETICS METHODS FOR VIRUS RESCUE  
A method for rescuing a virus by reverse genetics is provided in which cells are added after transfection.
US20140127262 REFRIGERATOR-TEMPERATURE STABLE INFLUENZA VACCINE COMPOSITIONS  
Methods and compositions for the optimization and production of refrigerator-temperature stable virus, e.g., influenza, compositions are provided. Formulations and immunogenic compositions...
US20140011188 METHODS FOR PRODUCING VIRUS PARTICLES WITH SIMPLIFIED GLYCOSYLATION OF SURFACE PROTEINS  
Methods for production of virus particles with simplified glycosylation on structural or surface proteins are provided. When used as targets for vaccine production, the conserved nature of such...
US20140205628 HIGH MOLECULAR WEIGHT POLYSACCHARIDE THAT BINDS AND INHIBITS VIRUS  
This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods of inhibiting viral infectivity and/or...
US20150093804 METHOD FOR PREPARING VIRUS-LIKE PARTICLE AND RECOMBINANT BACULOVIRUS USED THEREIN  
A recombinant baculovirus is provided for preparing picornavirus virus-like particles (VLP), wherein Chitinase A (ChiA) and Cathepsin V (v-cath) genes of the recombinant baculovirus are...
US20110129446 Clone of newcastle disease virus, its manufacture and its application in the medical treatment of cancer  
A new clone of Newcastle disease virus which is interferon insensitive and has an ICPI between 1.2 and 2.0 and which may be used in the treatment of cancer and other diseases.
US20130216573 INFLUENZA VIRUS REASSORTMENT  
Methods for producing reassortant viruses are provided wherein the transcription and/or translation of the hemagglutinin and/or neuraminidase genes are suppressed.
US20140186391 VACCINE AGAINST RSV  
Provided is a vaccine against respiratory syncytial virus (RSV), comprising a recombinant human adenovirus of serotype that comprises nucleic acid encoding a RSV F protein or immunologically...
US20110002959 Vaccine Production For Pathogenic Bird Viral Diseases  
The present invention is an improved method for the production of vaccines to transmittable viral pathogens where the virus is pathogenic to the chicken embryos. Bird embryos are selected for...
US20140061123 Prevention and Remediation of Petroleum Reservoir Souring and Corrosion by Treatment with Virulent Bacteriophage  
There is provided a safe, natural, environmentally sound means of controlling bacterial contamination, corrosion, and souring of oil and gas wells and reservoirs that result from...
US20100322971 METHOD FOR PRODUCING VACCINAL VIRAL STRAIN OF A VIRUS OF THE REOVIRIDAE FAMILY  
The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus...
US20130323302 TREATMENT OF AMD USING AAV SFLT-1  
The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a...
US20100317547 METHODS AND COMPOSITIONS  
The invention relates to a complex comprising a phage particle, said phage particle comprising (i) a polypeptide; (ii) a nucleic acid encoding the polypeptide of (i); (iii) a connector compound...
US20120058145 METHOD FOR PRODUCING VIRUS FROM CELL CULTURE INVOLVING HOMOGENIZATION  
A method of purifying a virus, or a viral antigen thereof, from a culture of infected cells comprising at least the steps of: (a) collecting the virus-containing cell culture medium, and (b)...
US20140134208 MULTI PLASMID SYSTEM FOR THE PRODUCTION OF INFLUENZA VIRUS  
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid...
US20120020997 MULTI PLASMID SYSTEM FOR THE PRODUCTION OF INFLUENZA VIRUS  
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid...
US20110014157 METHOD FOR PRODUCING A MIXTURE OF BACTERIOPHAGES AND THE USE THEREOF IN THE THERAPY OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCI  
The invention relates to a method for producing a mixture of bacteriophages, wherein at least two different bacteriophage strains have been reproduced separately, wherein a staphylococcus strain...
US20120088228 METHODS OF PRODUCING HIGH TITER, HIGH PURITY VIRUS STOCKS AND METHODS OF USE THEREOF  
The purity and titer of virus stocks used for virus clearance studies have a significant influence on study outcome, and impact how well the scale-down model represents the production-scale...
US20140206062 Recombinant Influenza Viruses for Vaccines and Gene Therapy  
The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the...
US20120156758 Recombinant Influenza Viruses for Vaccines and Gene Therapy  
The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the...
US20120156757 PURIFICATION OF IMMUNOGENS USING A NON-POLYSACCHARIDE MATRIX  
The present invention relates, at least in part, to novel and improved chromatography matrices for separating or purifying immunogens, such as, for example, viruses and viral surface proteins,...
US20120003266 VIRUS LIKE PARTICLE COMPOSITIONS AND METHODS OF USE  
The invention features compositions and methods for the prevention or treatment of one or more strains of Chikungunya virus, as well as other alphavirus-mediated diseases.
US20110217757 MODIFIED VACCINIA ANKARA VIRUS VARIANT AND CULTIVATION METHOD  
The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus and characterized by the loss of its capability to reproductively replicate in human cell...
US20140162342 METHODS AND COMPOSITIONS FOR PRODUCTION OF VACCINA VIRUS  
Certain embodiments are directed to viral production processes for the large scale production of vaccinia virus.
US20130115235 SWINE INFLUENZA HEMAGGLUTININ VARIANTS  
The technology relates in part to modified influenza viruses useful for vaccine development. Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin...
US20120115206 NON-TUMORIGENIC MDCK CELL LINE FOR PROPAGATING VIRUSES  
The present invention provides novel MDCK-derived adherent non-tumorigenic cell lines that can be grown in the presence or absence of serum. The cell lines of the present invention are useful for...
US20120190100 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS  
The present invention relates to an enzymatic composition for the digestion of chicken embryos intended to the preparation of cells which are used for the production of viruses. The present...
US20130164821 METHOD FOR SEPARATING VIRUSES FROM A CONTAMINANT-CONTAINING LIQUID  
The present invention relates to a method for separating viruses from a contaminant-containing liquid medium using two adsorbents having cationic groups, wherein the viruses are adsorbed to the...
US20120142078 SYSTEM FOR GENERATION OF VIABLE REOVIRUS FROM CLONED CDNA  
The present invention provides methods for the generation of viable reoviruses using only cloned nucleic acid segments representing the RNA segments of the reovirus genome.
US20130183742 METHOD FOR HARVESTING EXPRESSION PRODUCTS  
The present invention provides a method for recovering an essentially cell-associated expression product from a host cell comprising (a) culturing said host cell under conditions that allow...
US20140178969 VIRAL PURIFICATION METHODS  
The present invention is directed to an improved method of purifying virus, particularly reovirus. Infectious virus can be extracted from a cell culture with a detergent to produce high titers of...
US20110281329 PROCESS AND SYSTEM FOR THE INDUSTRIAL SCALE PURIFICATION OF BACTERIOPHAGES INTENDED FOR BACTERIOPHAGE THERAPY  
The present invention is directed towards bacteriophage therapy, the treatment of infectious diseases, caused by pathogenic bacteria, using specific bacteriophages. The purity of bacteriophage...
US20140079726 INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS  
Polypeptides, polynucleotides, reassortant viruses, immunogenic compositions and vaccines comprising influenza hemagglutinin and neuraminidase variants and method using thereof are provided.
US20120328651 CHIMPANZEE ADENOVIRUS VACCINE CARRIERS  
The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing...
US20130189762 MULTI PLASMID SYSTEM FOR THE PRODUCTION OF INFLUENZA VIRUS  
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid...
US20140023680 INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.
US20130243816 INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.
US20130189293 INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising (avian pandemic) influenza hemagglutinin and neuraminidase variants are provided.
US20130156810 INFLUENZA HEMAGGLUTININ AND NEURAMINIDASE VARIANTS  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.

Matches 1 - 50 out of 354 1 2 3 4 5 6 7 8 >