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US20120321612 |
SYSTEMS AND METHODS FOR TREATING POST-OPERATIVE, ACUTE, AND CHRONIC PAIN USING AN INTRA-MUSCULAR CATHETER ADMINISTRATED COMBINATION OF A LOCAL ANESTHETIC AND A NEUROTOXIN PROTEIN
Systems, and methods for the use of such systems, are described that allow for the administration of a combination of a sustained release local anesthetic compound (such as bupivicaine) through a... |
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US20140140983 |
METHOD FOR TREATMENT OF AUTONOMIC NERVOUS SYSTEM DISORDERS
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment of autonomic nervous system disorders such as irritable bowel syndrome. The neurotoxin is delivered to target the... |
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US20120093920 |
METHOD OF TREATMENT FOR BLADDER DYSFUNCTION
Liposomes are used for intravesical drug delivery, especially delivery of botulinum toxin (BoNT) to help improve lower urinary tract symptoms by decreasing bladder irritation and frequency. The... |
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US20130236446 |
TREATMENT OF MIGRAINE HEADACHE WITH DIFFUSION OF TOXIN IN NON-MUSCLE RELATED AREAS OF THE MOUTH
A method for treating a patient with migraine headache includes administering to the patient a therapeutically effective amount of an invertebrate presynaptic neurotoxin in a pharmaceutically safe... |
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US20140079687 |
Suture line Administration Technique using Botulinum Toxins
The present invention utilizes patient-specific landmarks in order to treat headache pain. In one aspect, the present invention relates to the administration of Clostridial toxins, such as a... |
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US20150216953 |
BOTULINUM TOXIN THERAPY FOR SKIN DISORDERS
Methods for treating skin disorders by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a skin disorder. |
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US20150010533 |
BOTULINUM TOXIN THERAPY FOR SKIN DISORDERS
Methods for treating skin disorders by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a skin disorder. |
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US20140030248 |
INJECTION PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional... |
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US20130330321 |
INJECTION PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional... |
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US20130224180 |
INJECTION PARADIGM FOR ADMINISTRATION OF BOTULINUM TOXINS
Disorders such as headaches can be treated by administration of a botulinum toxin to a patient suffering therefrom, such as a migraine headache. A combined a fixed site/fixed dose and an optional... |
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US20150030584 |
TRANSPORT PROTEIN WHICH IS USED TO INTRODUCE CHEMICAL COMPOUNDS INTO NERVE CELLS
The invention relates to a transport protein which can be obtained by modifying the heavy chain of the neurotoxin formed by Clostridium botulinum. The protein binds specifically to nerve cells... |
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US20150071879 |
Stabilization of Aqueous Compositions of Proteins with Displacement Buffers
An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least... |
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US20150064167 |
METHOD FOR TREATING PREMATURE EJACULATION WITH A BOTULINUM NEUROTOXIN
Methods for prolongation of climax time in a patient in need thereof are presented, as are methods for treating premature ejaculation by local administration of a Clostridial neurotoxin, such a... |
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US20140140981 |
METHOD FOR TREATING PREMATURE EJACULATION WITH A BOTULINUM NEUROTOXIN
Methods for prolongation of climax time in a patient in need thereof are presented, as are methods for treating premature ejaculation by local administration of a Clostridial neurotoxin, such a... |
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US20120148563 |
Method for Treating Premature Ejaculation with a Botulinum Neurotoxin
Methods for prolongation of climax time in a patient in need thereof are presented, as are methods for treating premature ejaculation by local administration of a Clostridial neurotoxin, such a... |
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US20140065130 |
METHOD FOR TREATING PREMATURE EJACULATION WITH A NEUROTOXIN
Methods for treating premature ejaculation and prolongation of climax time in a patient in need thereof by local administration of a Clostridial neurotoxin, such as a botulinum toxin, are provided. |
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US20110135704 |
Infection Control for Surgical and Trauma Patients
Apparatus and methods for disrupting the colonization of Staphylococcus aureus are disclosed. A lysostaphin antimicrobial coating for bone implants and a lysostaphin gel for use on open wounds to... |
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US20140294803 |
METHODS FOR TREATING HEADACHE
A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan medication can be increased. The... |
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US20140142718 |
FLEXIBLE TISSUE MATRIX AND METHODS FOR JOINT REPAIR
A synthetic, flexible tissue matrix and methods for repairing hyaline cartilage defects in a joint using the flexible tissue matrix are described. The flexible tissue matrix includes a high... |
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US20140328892 |
USE OF ALFIMEPRASE IN THE TREATMENT OF THROMBOSIS
Methods for treatment of arterial or venous thrombosis in patients undergoing an endovascular intervention or a surgical procedure, and more particularly, administering alfimeprase directly into... |
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US20150174216 |
Methods for Treating Adhesive Capsulitis
The invention relates to the discovery that collagenase injections are effective in lyse the collagenous adhesions in the shoulder and treat the disorder, adhesive capsulitis. As such, the... |
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US20130330320 |
Methods for Treating Adhesive Capsulitis
The invention relates to the discovery that collagenase injections are effective in lyse the collagenous adhesions in the shoulder and treat the disorder, adhesive capsulitis. As such, the... |
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US20140335072 |
Method of Treating or Reducing EFP
The present invention is directed to a method of treating or reducing EFP in a patient comprising administering one or multiple low dose injections of collagenase to an area affected by EFP. The... |
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US20120282241 |
Method of Treating Persistent Genital Arousal Disorder with a Neurotoxin
A method of controlling dysregulation of the dorsal cutaneous nerve of the clitoris and, in particular, a method for treating PGAD is provided. In one aspect, the method comprises administering a... |
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US20150079069 |
METHODS FOR MODIFICATION OF TISSUES
Methods for modification of mechanical properties or a shape of a mammalian tissue, excluding scar, blood clot, fat; including a step of contacting the tissue with an isolated eukaryotic... |
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US20140170132 |
PROPHYLATIC TREATMENT OF HERPES RECURRENCE
The present invention relates to methods for prophylactic treatment of Herpes recurrence with a Clostridial neurotoxin, such as a botulinum neurotoxin or variant thereof. |
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US20140322197 |
METHODS FOR TREATMENT OF HIP AND GROIN PAIN ASSOCIATED WITH FEMOROACETABULAR IMPINGEMENT (FAI)
Methods for treating or alleviating symptoms associated with femoroacetabular impingement (FAI) by local administration of a clostridial derivative, such as a botulinum toxin, to the hip capsule... |
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US20140193394 |
TREATMENT OF CARPAL TUNNEL SYNDROME BY INJECTION OF THE FLEXOR RETINACULUM
An apparatus and method for identifying the flexor retinaculum of the carpal tunnel, injecting an effective amount of an agent into at least a portion of flexor retinaculum or tissue adjacent... |
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US20140248258 |
METHODS FOR IMPROVING GUT HEALTH
The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins,... |
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US20120225050 |
METHODS FOR IMPROVING GUT HEALTH
The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins,... |
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US20150165003 |
LONG LASTING EFFECT OF NEW BOTULINUM TOXIN FORMULATIONS
The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free... |
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US20130195838 |
Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases
The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions. |
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US20100310544 |
COMPOSITION COMPRISING CALCIUM IONS AND AT LEAST ONE PROTEOLYTIC ENZYME FOR USE IN THE IN VITRO AND IN VIVO REGENERATION OF CUTANEOUS AND CONNECTIVE TISSUES
The invention is based on the finding that calcium ions and proteolytic enzymes, particularly papain, act in a synergetic way in the regeneration of skin and connective tissues. Thus, such a... |
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US20110044960 |
MEDICAMENT, DENTAL MATERIAL, AND METHOD OF SCREENING
The present invention provides a novel and creative dental materials for treatment of pulpitis and/or enhancement of dentinogenesis. The dental materials of the present invention contain at least... |
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US20110081320 |
Treatment/Cure of Autoimmune Disease
An embodiment entails administering an effective amount of a product such as a protease or a source of a protease that destroys or deactivates an immunogen, mimic or antigen specific to a... |
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US20150093373 |
TREATMENT OF PULMONARY VASCULAR REMODELING WITH NEPRILYSIN
The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming... |
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US20120121573 |
Treatment of Pulmonary Vascular Remodeling With Neprilysin
The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming... |
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US20140271611 |
SUBCUTANEOUS ADMINISTRATION OF ADAMTS13
This invention relates to methods of subcutaneous administration of ADAMTS13 formulations to a treat a disease or condition associated with ADAMTS13 and VWF dysfunction. Furthermore, evidence of... |
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US20120195878 |
PROTOCOL FOR THE ADMINISTRATION OF BOTULINUM TOXINS
Embodiments of the invention provide treatment methods utilizing botulinum toxins. Certain methods describe specific time intervals between administration sessions. Administration sessions can... |
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US20110256095 |
Tissue Matrix System
The present application discloses matrix compositions to support the repair of tissue defects such as an injury to tendon tissue, ligament tissue, vascular tissue, dermal tissue, or muscle tissue.... |
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US20140178357 |
STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable... |
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US20110229455 |
STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable... |
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US20140170106 |
METHODS AND COMPOSITIONS SUITABLE FOR IMPROVED REATTACHMENT OF DETACHED CARTILAGE TO SUBCHONDRAL BONE
The methods and compositions disclosed herein are effective in the promoting the reattachment of delaminated cartilage to bone. The methods (and related compositions) comprise the removal of the... |
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US20120189677 |
FORMULATIONS
A formulation comprising botulinum toxin (BT), lipid and surfactant, characterised in that the lipid and surfactant are in the form of macromolecular assemblies of less than 100 nm in diameter.... |
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US20140154237 |
METHODS AND KITS FOR TOPICAL APPLICATION, REMOVAL, AND INACTIVATION OF THERAPEUTIC OR COSMETIC TOXIN COMPOSITIONS
This invention relates to methods and kits for safely removing and inactivating topical therapeutic or cosmetic compositions. The methods and kits according to the invention are particularly well... |
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US20120294844 |
Methods And Kits For Topical Application, Removal, And Inactivation Of Therapeutic Or Cosmetic Toxin Compositions
This invention relates to methods and kits for safely removing and inactivating topical therapeutic or cosmetic compositions. The methods and kits according to the invention are particularly well... |
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US20120282242 |
COMPOSITIONS, TARGETS, METHODS AND DEVICES FOR THE THERAPY OF OCULAR AND PERIOCULAR DISORDERS
Methods for treating ocular and periocular disorders by administration to a human patient of a therapeutically effective amount of a compound that modulates muscle action. |
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US20110091421 |
Methods of Novel Therapeutic Candidate Identification Through Gene Expression Analysis in Vascular-Related Diseases
The present invention discloses multiple treatment regimens for vascular-related diseases and disorders. The present invention provides for methods of treating vascular-related disorders based on... |
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US20140199288 |
PHARMACEUTICAL COMPOSITIONS CONTAINING BOTULINUM NEUROTOXIN
This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides.... |
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US20140212405 |
Fibrinolytic/Proteolytic Treatment of Myofacial and Neuropathic Pain and Related Conditions
A method is disclosed to dissolve protein deposited in muscle. The method includes the step of administering an effective amount of an agent selected from the group consisting of fibrinolytics,... |