Matches 1 - 50 out of 126 1 2 3 >


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US20110002904 SYNOVIAL VILLI FOR USE WITH TISSUE ENGINEERING  
Synovial villi derived explants and related surgical tools used to repair or prevent damage to injured or diseased tissue, including connective tissue. The tools including a harvesting tool for...
US20120141540 Drug Delivery System  
Red blood cells can be used as effective drug delivery systems when they contain proteins that do not readily diffuse out and which form affinity complexes with the desired drug.
US20150240309 Methods and Tools for Vel Blood Group Typing  
The present invention relates to methods and tools for discriminating between Vel negative and Vel positive phenotypes. The invention is thus useful for determining Vel blood group status of...
US20100322911 USE OF MICROWAVE IRRADIATION FOR DELIVERY OF MACROMOLECULES  
The present invention is directed to methods of delivering macromolecules to a target cell or tissue by microwave irradiation. A target cell or tissue is exposed to one or more macromolecules to...
US20140369984 BIOMATERIAL FOR ARTICULAR CARTILAGE MAINTENANCE AND TREATMENT OF ARTHRITIS  
The present disclosure provides biomaterials and methods for preventing and minimizing progression of cartilage and/or connective tissue damage. Also provided herein are biomaterials and methods...
US20100316620 Formulation and Method for the Prevention and Treatment of Skeletal Manifestation of Gaucher's Disease  
The invention relates to the prevention and treatment of skeletal manifestation of Gaucher's disease. It relates to a formulation for introducing glucocerebrosidase into the lysosomal compartment...
US20140170127 INOSITOL PYROPHOSPHATES, AND METHODS OF USE THEREOF  
The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm...
US20140271591 Compositions and methods for the modulation of hemoglobin (s)  
This invention provides pharmaceutical compositions for the allosteric modulation of hemoglobin (S) and methods for their use in treating disorders mediated by hemoglobin (S) and disorders that...
US20110262415 ERYTHROCYTE-BASED DELIVERY SYSTEM, METHOD OF PREPARATION AND USES THEREOF  
The invention relates to a cell-based drug delivery system comprising magneto nanoparticles, erythrocytes and a fusion-protein, its preparation and uses thereof in particular as a delivery system...
US20110086012 Rejuvenation Method  
A rejuvenation method includes a) removing blood or tissue from a human body or animal body, b) nurturing and purifying the blood or tissue, and c) implanting the blood or tissue that has been...
US20140219980 TREATMENT FOR MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOMYOPATHY (MNGIE)  
The invention provides a method of treating mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) in a patient, comprising administering to the patient autologous erythrocytes that contain...
US20140086892 RED BLOOD CELL PRODUCTS AND THE STORAGE OF RED BLOOD CELLS IN NON-PVC CONTAINERS  
Red blood cell products are disclosed. The product includes a container made from a non-PVC, substantially plasticizer-free material. The product includes a RBC concentrate and a hypotonic...
US20140308260 METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS  
The invention provides methods, compositions, and medical kits comprising a nitrite-reductase promoter, such as an allosteric modulator of hemoglobin, for use in treating medical disorders and...
US20130259845 TREATMENT OF PREMATURE BIRTH COMPLICATIONS  
The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood...
US20120016489 TEXTURED BONE BLOCK IMPLANTS  
Implantable pliable bone blocks comprising a solid block of cortical bone characterized by a length, width and thickness, having a first and a second face on opposite sides of the block. The first...
US20140091047 RED BLOOD CELL PRODUCTS AND THE STORAGE OF RED BLOOD CELLS IN CONTAINERS FREE OF PHTHALATE PLASTICIZER  
Red blood cell products and compositions are disclosed. The product includes a container made from PVC or a non-PVC material that is substantially free of a phthalate plasticizer but otherwise...
US20150064155 METHODS FOR TREATMENT OF CERVICAL INSUFFICIENCY  
Methods, compositions, devices and kits for increasing mechanical stiffness of an incompetent or a dilated biological tissue in a subject are provided herein. The methods described herein involve...
US20110286987 QUENCHING METHODS FOR RED BLOOD CELL PATHOGEN INACTIVATION  
The present invention provides improved methods for treating red blood cell compositions with a pathogen-inactivating compound under conditions which provide suitable pathogen inactivation while...
US20130202625 USE OF HUMAN ERYTHROCYTES FOR PREVENTION AND TREATMENT OF CANCER DISSEMINATION AND GROWTH  
The technology relates in part to methods of preventing and treating diseases and conditions associated with cancer, including methods, compositions, and kits used for preventing and treating...
US20150250782 Methods and Compositions for Hypotensive Resuscitation  
Methods of treating diseases and conditions wherein an improvement in cardiac output, organ perfusion, or tissue oxygenation are disclosed. The methods include treatments of diseases and...
US20110070210 SYSTEMS AND METHOD FOR HOMEOSTATIC BLOOD STATES  
Decades of investigations were focused on finding “gold standard” for evaluation of plasma dilution and osmolality, blood loss evaluation and prediction of bleeding or transfusion induced changes...
US20130209430 METHODS FOR REGULATION OF STEM CELLS  
Methods are provided for increasing stem cells, hematopoietic progenitor/stem cells, mesenchymal progenitor/stem cells, mesodermal progenitor/stem cells, muscle progenitor/stem cells, or neural...
US20140314728 2-HYDROXYGLUTARATE AS A BIOMARKER FOR CHRONIC HYPOXIA  
The present invention provides biomarkers for sensitive, specific, accurate and quantitative diagnosis and assessment of chronic hypoxia. In particular, the present invention provides...
US20080267936 Treatment of trauma-hemorrhage with short oligopeptides  
Described are methods and associated means for treating a subject, such as a mammal, experiencing or thought to be at risk for hemorrhagic shock. Such methods include administering to the subject...
US20140363413 FORMULATION AND METHOD FOR THE PREVENTION AND TREATMENT OF BONE METASTASES OR OTHER BONE DISEASES  
A suspension of erythrocytes encapsulating a bisphosphonate is provided along with a method for its use for the prevention and treatment of bone metastases and other bone marrow diseases. The...
US20140010795 FORMULATION AND METHOD FOR THE PREVENTION AND TREATMENT OF BONE METASTASES OR OTHER BONE DISEASES  
A suspension of erythrocytes encapsulating a bisphosphonate is provided along with a method for its use for the prevention and treatment of bone metastases and other bone marrow diseases. The...
US20150192576 METHODS AND REAGENTS FOR PREVENTION AND/OR TREATMENT OF TRANSPLANT REJECTION  
The present invention relates to methods for determining the probability of transplant rejection based on the determination in the subject recipient of the transplant of the levels of antibodies...
US20130209431 ISOLATION AND CULTURE OF ERYTHROID PROGENITOR CELLS  
Disclosed herein are methods of isolating erythroid progenitor cells from a source of human hematopoietic cells and methods of culturing the isolated erythroid progenitor cells in vitro to produce...
US20140212397 METHODS FOR REJUVENATING RED BLOOD CELLS  
Methods for transfusing blood to a mammalian subject. The method includes obtaining a unit of blood, rejuvenating the blood with an enhancement composition, measuring 2,3-DPG concentration of the...
US20140301997 COMPOSITION FOR A MITOTIC REMODELING OF CHROMOSOMES  
A composition of a female germinal cell (egg) extract of pluricellular organisms in M-phase of the cell cycle, the extract being used for a mitotic remodeling of chromosomes of donor cells of...
US20150203819 PRODUCTION OF RED BLOOD CELLS AND PLATELETS FROM STEM CELLS  
This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a MEP precursor cell into a MEP in culture in the presence of an aryl...
US20140050711 PRODUCTION OF RED BLOOD CELLS AND PLATELETS FROM STEM CELLS  
This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a stem cell into a MEP in culture in the presence of an aryl hydrocarbon...
US20090136471 TREATMENT OF PREMATURE BIRTH COMPLICATIONS  
The present invention provides methods of treating one or more complications of premature birth suffered by premature infants, comprising administering to the premature infant umbilical cord blood...
US20110177045 Use of Mesenchymal Stem Cells for Treating Genetic Disease and Disorders  
A method of treating a genetic disease or disorder such as, for example, cystic fibrosis, Wilson's disease, amyotrophic lateral sclerosis, or polycystic kidney disease, in an animal comprising...
US20120230969 METHOD AND PRODUCT FOR BLOOD TREATMENT AND PURIFICATION  
Extracorporeal blood treatment is performed daily on a large number of patients by use of for example a dialysis filter, plasma filter or a centrifuge. The purpose of the treatment is to separate...
US20140255369 PRODUCTION AND USE OF RED BLOOD CELLS  
The present disclosure relates to the production of red blood cells from hematopoietic stem cells, by differentiating such cells in the presence of a protein that induces cell survival and...
US20140212400 METHODS FOR REJUVINATING RED BLOOD CELLS  
Methods and a system for transfusing blood to a mammalian subject. The method includes obtaining a volume of donated red blood cells (RBCs), adding an enhancement composition to the RBCs to form a...
US20120225045 REOVIRUS CLEARANCE OF RAS-MEDIATED NEOPLASTIC CELLS FROM MIXED CELLULAR COMPOSITIONS  
Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with...
US20140121640 MULTIPURPOSE MEMBRANES, METHODS FOR FORMING, AND APPLICATIONS THEREOF  
One aspect of the present disclosure relates to a method for forming a multipurpose membrane in vivo. One step of the method includes obtaining a blood component. Next, a vacuum assembly is...
US20150071894 Test for Predicting Neutralization of Asparaginase Activity  
Method of in vitro measurement of the presence of factors that are able to neutralize asparaginase activity in a sample of blood, plasma, serum or derived medium that may contain asparaginase...
US20150017146 METHOD OF ENHANCING EFFICACY OF BLOOD TRANSFUSIONS  
A method of improving the efficacy of a blood transfusion into a subject is provided comprising administering a composition comprising an EAF PEGylated-blood protein into the subject, prior to,...
US20150246077 Regeneration of Spinal Discs  
Compositions and processes for the effective and efficient regeneration of spinal discs are provided. These compositions contain stem cells, donor cells, and platelet plasma compositions. By using...
US20140227240 Regeneration of Spinal Discs  
Compositions and processes for the effective and efficient regeneration of spinal discs are provided. These compositions contain stem cells, donor cells, and platelet plasma compositions. By using...
US20120076750 FIBRIN BASED GLUE WITH FUNCTIONALIZED HYDROPHILIC POLYMER PROTEIN BINDING AGENT  
The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent,...
US20110177036 WHOLE BLOOD CULTURES COMPRISING STIMULATED IMMUNE CELLS, AND USE THEREOF AS MEDICAMENTS  
The present invention relates to a whole-blood culture containing specific immunocompetent killer cells that are activated against tumor cells, viruses, bacteria and/or allergens, whereby the...
US20120148577 USE OF HIGH-DOSE, POST-TRANSPLANTATION OXAZAPHOSPHORINE DRUGS FOR REDUCTION OF TRANSPLANT REJECTION  
A lymphocytotoxic, but hematopoietic stem cell-sparing, high-dose amount of an oxazaphosphorine drug such as, for example, cyclophosphamide, administered post-transplantation can be used to reduce...
US20080027413 Blood Products from Mesenchymal Stem Cells  
A method of producing blood products in vitro and a method of treatment are provided. The methods include culturing isolated non-SV40 transformed mesenchymal stem cells with growth factors for a...
US20140140987 Manufacturing and Purification Processes of Complex Protein found in Fraction IV to make a separated Apo, Transferrin, and Alpha 1 Anti strepsin (A1AT) or A combined Transferrin/Apo/Human Albumin/A1AT and all new found proteins  
A method of introducing healthy good human cells to eat up bad damaged cells, comprising administering an effective amount of a healthy good protein containing transferrin, alpha 1-antitrypsin,...
US20140369985 REMOVAL OF TUMOR CELLS FROM INTRAOPERATIVE AUTOLOGOUS BLOOD SALVAGE  
The invention relates to a method performed ex vivo for removal of tumor cells from intraoperatively collected blood salvage, to antibodies and scaffold proteins which mimic antibodies for use in...
US20110070209 Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs  
Acute and chronic diseases of the organs are treated in patients using a rational, multi-tier approach. A patient can be pretreated with growth factor proteins or gene therapy, followed by the...

Matches 1 - 50 out of 126 1 2 3 >