Matches 1 - 50 out of 326 1 2 3 4 5 6 7 >


Match Document Document Title
US20150165059 SOLUBLE GLYCOSAMINOGLYCANASES AND METHODS OF PREPARING AND USING SOLUBLE GLYCOSAMINOGLYCANASES  
The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules...
US20140294773 MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF  
A clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for adaptive antiviral defence (Cascade); the Cascade protein complex comprising at least CRISPR-associated...
US20120164108 VIRUS STRAINS  
The present invention relates to non-laboratory virus strains, for example of herpes viruses such as HSV, with improved oncolytic and/or gene delivery capabilities as compared to laboratory virus...
US20120065071 METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS  
The present invention provides a composition including a polymer nanoparticle and at least one agricultural active compound incorporated with the nanoparticle, wherein the nanoparticle are less...
US20090123382 Light emitting microorganisms and cells for diagnosis and therapy of tumors  
Provided are diagnostic and pharmaceutical compositions containing a microorganism or a cell containing a DNA molecule encoding a detectable protein or a protein that a detectable signal, such as...
US20090098089 REOVIRUS FOR THE TREATMENT OF NEOPLASIA  
Methods for treating neoplasia, by administering reovirus to a Ras-mediated neoplasm, are disclosed. The reovirus is administered so that it ultimately directly contacts cells of the neoplasm....
US20080050345 Adeno-associated virus serotype I nucleic acid sequences, vectors and host cells containing same  
The nucleic acid sequences of adeno-associated virus (AAV) serotype 1 are provided, as are vectors and host cells containing these sequences and functional fragments thereof. Also provided are...
US20150352135 GLA Monotherapy for Use in Cancer Treatment  
The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.
US20120148505 Reduction In Bacterial Colonization By Administering Bacteriophage Compositions  
The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition...
US20120034164 TRUNCATED CAR PEPTIDES AND METHODS AND COMPOSITIONS USING TRUNCATED CAR PEPTIDES  
Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods...
US20110223153 MODIFIED SILK FILMS CONTAINING GLYCEROL  
The present invention provides for compositions and methods for preparing aqueous insoluble, ductile, flexible silk fibroin films. The silk films comprise silk fibroin and about 10% to about 50%...
US20110097385 Delivery System for Drug and Cell Therapy  
A method of lowering blood glucose in a mammal includes administering orally or by injection or inhalation a therapeutically effective amount of crystallized dextran microparticles and insulin to...
US20090214617 IMMOBILISATION AND STABILISATION OF VIRUS  
The present invention relates to a method for immobilization and optional stabilization of viruses whilst retaining the viral biological activity and the use of immobilized virus in therapy. In...
US20090110665 REOVIRUS FOR THE TREATMENT OF NEOPLASIA  
Methods for treating neoplasia, by administering reovirus to a Ras-mediated neoplasm, are disclosed. The reovirus is administered so that it ultimately directly contacts cells of the neoplasm....
US20170079920 Technology for the Preparation of Microparticles  
Microspheres are produced by contacting a solution of a macromolecule or small molecule in a solvent with an antisolvent and a counterion, and chilling the solution. The microspheres are useful...
US20130164374 REDUCTION IN BACTERIAL COLONIZATION BY ADMINISTERING BACTERIOPHAGE COMPOSITIONS  
The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition...
US20120328575 Modified Oncolytic Viruses  
The present invention provides an isolated selected Picornavirus capable of lytically infecting or inducing apoptosis in a cell substantially in the absence of intercellular adhesion molecule-1...
US20120269861 TREATMENT OF BREAST CANCER WITH IODONITROBENZAMIDES IN COMBINATION WITH ANTI-TUMOR AGENTS  
In one aspect, the present invention provides a method of treating breast cancer that is negative for ER, PR, and HER2, comprising administering to a subject at least one iodonitrobenzamide. In...
US20110243996 Spray freeze dry of compositions for intranasal administration  
This invention provides methods and compositions to preserve bioactive materials, such as peptides, nucleic acids, viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for...
US20100196325 Use of modified vaccinia virus strains in combination with a chemotherapeutic agent for use in therapeutic methods  
Modified or attenuated therapeutic viruses in combination with a chemotherapeutic agent, and methods for administering therapeutic viruses in combination with a chemotherapeutic agent to a subject...
US20080254132 High pressure spray-dry of bioactive materials  
This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive...
US20160143968 TREATMENT METHODS USING ADENOVIRUS  
The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor by inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient...
US20160015760 NEWCASTLE DISEASE VIRUSES AND USES THEREOF  
Described herein are chimeric Newcastle disease viruses engineered to express an agonist of a co-stimulatory signal of an immune cell and compositions comprising such viruses. Also described...
US20150038329 MESOIONIC PESTICIDES  
Disclosed are compounds of Formula 1, wherein R1 is phenyl or pyridinyl, each optionally substituted with Q and up to 3 substituents independently selected from R2;each R2 is independently...
US20130209546 COMBINATORIAL METHODS AND COMPOSITIONS FOR TREATMENT OF MELANOMA  
The invention relates to combining targeted therapies with selected chemotherapeutics for the treatment of melanoma. The invention provides a method for inducing apoptosis in a melanoma tumor cell...
US20090220460 VIRUS STRAINS  
The present invention relates to clinical herpes simplex virus (HSV) isolates with improved oncolytic capabilities as compared to reference laboratory HSV strains. The present invention also...
US20090162398 Methods and Compositions for Immunizing Pigs Against Porcine Circovirus  
The present invention relates to the isolation and identification of two new strains of type 2B porcine circovirus. These two new strains of porcine circovirus may be used for the preparation of...
US20160289681 RNA-BASED HIV INHIBITORS  
Provided herein are, inter alia, antiviral recombinant nucleic acid compositions and methods of using the same. The recombinant nucleic acid compositions include nucleic acids encoding antiviral...
US20150284472 COMPOSITIONS AND METHODS FOR TREATING PROTEINOPATHIES  
This disclosure relates to methods for improving neural function in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases...
US20100129399 LINEAR EXPRESSION CONSTRUCTS FOR PRODUCTION OF INFLUENZA VIRUS PARTICLES  
The present invention provides a linear expression construct free of any conventional amplification and/or selection sequences comprising an RNA polymerase I (polI) promoter and a polI termination...
US20090110662 MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER  
The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
US20090104114 Nanotherapeutic Colloidal Metal Compositions and Methods  
The present invention comprises compositions and methods for delivery systems of agents, including therapeutic compounds, pharmaceutical agents, drugs, detection agents, nucleic acid sequences and...
US20080286237 Systemic Treatment of Metastatic and/or Systemically-Disseminated Cancers using GM-CSF-Expressing Poxviruses  
The present invention concerns methods and compositions for the treatment of cancer and cancer cells using intravascular administration of a vaccinia virus. In some embodiments, methods and...
US20080063662 VACCINE  
The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major...
US20070292397 METHOD FOR THE DETECTION AND NEUTRALIZATION OF BACTERIA  
The present invention relates to the identification of bacteria present at the site of infection and the treatment of the infection using bacteriophage. In certain embodiments, the present...
US20060078538 Thermal surgical procedures and compositions  
Methods, compositions, and systems useful to enhance a thermal surgical procedure are described. Compositions include at least one compound effective to induce an inflammatory response in...
US20050191279 Biologic-chemical fungicide compositions and methods of use  
The present invention is directed to biologic-chemical fungicide compositions (BCFs) that include one or more chemical fungicides, and microorganisms including gram-positive and/or gram-negative...
US20050175991 Method for produce sanitation using bacteriophages  
A method for produce sanitation using bacteriophages is disclosed. According to one embodiment of the present invention, the method includes the steps of (1) providing at least one bacteriophage;...
US20120070427 VORTEX-INDUCED SILK FIBROIN GELATION FOR ENCAPSULATION AND DELIVERY  
The present invention provided for a novel process of forming silk fibroin gels, and controlling the rate of β-sheet formation and resulting hydrogelation kinetics, by vortex treatment of silk...
US20100215580 Compositions and methods for enhancing transport through mucus  
The invention generally relates to compositions and methods for transporting substances across mucosal barriers. The invention also relates to methods of making and using such substances.
US20090208495 ANTI-TUMOR EFFECTIVE PARAMYXOVIRUS  
Paramyxovirus from the group APMV3, APMV4, APMV5, APMV6, APMV7, APMV8, APMV9, Mapueravirus and Fer-de-Lance virus are described, which can be used for the production of a medicament for the...
US20080057097 MEDICAL DEVICES HAVING A COATING FOR PROMOTING ENDOTHELIAL CELL ADHESION  
A medical device having a coating of cell adhesion polypeptides to enhance endothelial cell adhesion onto the medical device. The cell adhesion polypeptides may be any of the proteins of the...
US20070274908 METHODS AND COMPOSITIONS RELATED TO ADENOASSOCIATED VIRUS-PHAGE PARTICLES  
Embodiments of the invention are generally directed to compositions and methods of delivering one or more transgene to a target cell, such as a tumor cell, in a site-specific manner to achieve...
US20150297642 COMPOSITIONS FOR THE RESTORATION OF A FECAL MICROBIOTA AND METHODS FOR MAKING AND USING THEM  
In alternative embodiments, the invention provides compositions and methods for treating various disorders and conditions in mammals, including chronic disorders in which there is a presence of an...
US20140086976 Compositions containing protein polymers and vaccinia virus, and methods of use thereof  
Provided herein are compositions containing a vaccinia virus and a protein polymer, and articles of manufacture thereof. Also provided are diagnostic and therapeutic methods using the compositions...
US20110243890 Sensitization of Chemotherapeutic Agent Resistant Neoplastic Cells With a Virus  
The present invention relates to a method of increasing the sensitivity of neoplastic cells to chemotherapeutic agents by using a virus, a method of treating proliferative disorders with a virus...
US20090130174 POLY (ESTER URETHANE) UREA FOAMS WITH ENHANCED MECHANICAL AND BIOLOGICAL PROPERTIES  
A biodegradable polyurethane scaffold that includes a HDI trimer polyisocyanate and at least one polyol; wherein the density of said scaffold is from about 50 to about 250 kg m-3 and the porosity...
US20090053186 Therapy for primary and metastatic cancers  
The present invention relates to compositions and methods for ablating tumor cells in a subject having at least one tumor site. More specifically, the method comprises contacting the tumor cells...
US20050063957 Antibacterial therapy with bacteriophage genotypically modified to delay inactivation by the host defense system  
The present invention is directed to bacteriophage therapy, using methods that enable the bacteriophage to delay inactivation by any and all parts of the host defense system (HDS) against foreign...
US20160250268 METHOD OF TREATING A MALIGNANCY IN A SUBJECT AND A PHARMACEUTICAL COMPOSITION FOR USE IN SAME  
There is a disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement...

Matches 1 - 50 out of 326 1 2 3 4 5 6 7 >