Matches 1 - 41 out of 41


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US20110189102 COATED QUANTUM DOTS AND METHODS OF MAKING AND USING THEREOF  
The present disclosure provides embodiments of a new class of hydroxylated quantum dots. The quantum dots have a hydroxylated coat disposed thereon, and which serves to minimize non-specific...
US20130202525 MULTIFUNCTIONAL NANOPLATFORMS FOR FLUORESCENCE IMAGING AND PHOTODYNAMIC THERAPY DEVELOPED BY POST-LOADING PHOTOSENSITIZER AND FLUOROPHORE TO POLYACRYLAMIDE NANOPARTICLES  
A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and a postloaded imaging agent and methods for making and using same.
US20110182825 METHODS AND DEVICES FOR ASSESSMENT OF MITOCHONDRIAL FUNCTION  
Mitochondrial function is measured. Repetitive or continuous measurements are performed of prompt red fluorescence, emerging from the skin due to PpIX build up, and/or delayed fluorescence of...
US20110091390 WATER SOLUBLE TETRAPYROLLIC PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY  
A tetrapyrollic photosensitizer compound having at least one pendant —CH2CH2CON(CH2CON(CH2COOH)2)2 or —N(CH2COOH)2 group or esters thereof said tetrapyrollic compound being a chlorin,...
US20150071862 FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES  
Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the...
US20120064012 Uniform Fluorescent Microspheres with Hydrophobic Surfaces  
Fluorescent microspheres for the measurement of blood flow are provided. The microspheres are substantially uniform in diameter and have a hydrophobic surface, which allows them to circulate more...
US20110091373 PAA NANOPARTICLES FOR ENHANCEMENT OF TUMOR IMAGING  
A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and an imaging agent and methods for making and using same.
US20140154186 BACTERIOCHLORIN IMIDES  
Compound of Formula I: are described, along with compositions containing the same and methods of use thereof.
US20130195758 PAA NANOPLATFORMS CONTAINING FLUOROPHORES AND TARGETED MOIETIES COVALENTLY LINKED AND PHOTOSENSITIZER POST-LOADED  
A PAA nanoparticle containing a covalently linked fluorescent dye and a post-loaded tetrapyrrolic photosensitizer.
US20120020893 Intravascular Imaging Device and Uses Thereof  
The invention is directed to a probe-type imaging device useful to visualize interior surfaces, e.g., the lumen of blood vessels. Specifically, the probe-type device is particularly useful for...
US20090041672 Drug for Treating or Diagnosing Vascular Lesion in the Skin or the Subcutaneous Soft Tissue Caused by Light Irradiation  
A novel drug for treating a vascular lesion in the skin or the subcutaneous soft tissue caused by light irradiation which is efficacious in treating a vascular lesion in the deep part of the skin...
US20140147380 GUANYLYLCYCLASE C LIGANDS  
Guanylin cyclase C compound of the inventions are disclosed. Conjugated compounds comprising guanylin cyclase C compound of the inventions conjugated to detectable or therapeutic moieties are...
US20100303732 DIAGNOSTIC SUBSTANCES FOR OPTICAL IMAGING TESTING ON THE BASIS OF NANOPARTICULAR FORMULATIONS  
The present invention relates to the provision of nanoparticular formulations comprising a PEG-alkyl block copolymer and a near infrared fluorescent dye, the preparation of these nanoparticular...
US20140294735 POLYMER-TYPE FLUORESCENT MOLECULE PROBE  
The present invention provides a fluorescent molecular probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic treatment,...
US20100247447 DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS  
Compositions comprising microaggregates containing hydrophobic drugs, as well as methods for their production, are described. Such microaggregates may include micelle structures or combinations...
US20150132230 PROTEASE ASSAY  
The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell....
US20110293531 Porphyrazine Optical and Dual Optical/MR Contrast and Therapeutic Agents  
Porphyrazines capable of localizing in a tumor of a mammal are disclosed. The porphyrazines are used in methods of imaging a tumor and in methods of treating tumors, either alone or in combination...
US20090117053 LOCAL DELIVERY OF 5-AMINOLEVULINIC-ACID BASED COMPOUNDS TO TISSUES AND ORGANS FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES  
In accordance with an aspect of the present invention, a 5-aminolevulinic-acid-based compound (ALA-based compound) is delivered locally to a tissue or organ within a subject's body. In another...
US20100239506 METHODS FOR DETECTION AND DETERMINATION OF VITAMIN C BY LUMINESCENCE  
The present invention provides a method for detection or determination of vitamin C by luminescence that employs a redox-responsive fluorogenic probe consisting of porphyrin or phthalocyanine with...
US20110319808 ANTIMICROBIAL COMPOSITION  
A composition for use on skin and wounds, comprising a photo-catalyst which is capable of preferentially staining biofilms the composition being for use in the diagnosis and treatment of biofilms...
US20120308485 PROCESS FOR THE PREPARATON OF NOVEL PORPHYRIN DERIVATIVES AND THEIR USE AS PDT AGENTS AND FLUORESCENCE PROBES  
The present invention provides novel porphyrin derivatives represented by the general formula 1 and/or pharmaceutically acceptable derivatives thereof as NIR sensitizers for photodynamic...
US20150202331 Sulfonic Esters of Metal Oxides and Methods of Their Use  
The present disclosure is directed to sulfonic esters of metal oxides including those of formulas I and II:
US20140286875 OXYGEN SENSORS  
Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
US20090016965 INTERNAL IMAGE ANTIBODIES FOR OPTICAL IMAGING AND THERAPY  
Methods using internal image antibodies for photodiagnosis and/or phototherapy. The internal image antibodies are conjugated with a photoactive molecule such as a dye or photosensitizer, to target...
US20140255317 PREPARATION COMPRISING HEXOSE-6-PHOSPHATE-MODIFIED CHOLESTEROL DERIVATIVE  
Provided is a compound represented by the general formula (1) (where: G represents a hexose-6-phosphate residue; and L represents a divalent linker group).
US20090297456 SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS  
Porphyrinic compounds that contain solubilizing groups are described, along with methods of making and using the same and compositions comprising such compounds. Examples of such compounds include...
US20150238773 WATER SOLUBLE ANIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND THEIR USES  
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or...
US20110117029 WATER-SOLUBLE ANIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND THEIR USES  
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (Bchls) containing at least one, preferably two or three, negatively charged groups and/or...
US20120232463 DE NOVO SYNTHESIS OF BACTERIOCHLORINS  
A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be...
US20110177007 Dithienopyrrole Dyes for Imaging and Therapy  
The invention provides optical agents, including compositions, preparations and formulations, and methods of using and making optical agents. Optical agents of the present invention include dyes,...
US20110177006 Dithienofuran Dyes for Imaging and Therapy  
The invention provides optical agents, including compositions, preparations and formulations, and methods of using and making optical agents. Optical agents of the present invention include dyes,...
US20070128116 MULTIFUNCTIONAL CORE FOR MOLECULAR IMAGING AND TARGETED DELIVERY OF MACROMOLECULES AND DRUGS  
In the broadest sense an inventive conjugate includes a macrocyclic scaffold moiety incorporating at least one nitrogen atom. Through linkages to the ring, nitrogen atoms are bonded to at least...
US20170145035 SYNTHESIS AND COMPOSITION OF PHOTODYNAMIC THERAPEUTIC AGENTS FOR THE TARGETED TREATMENT OF CANCER  
The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria...
US20170014532 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF  
The present invention provides various fluorescent conjugated polymers with a BODIPY-based backbone. The invention also provides methods of using the polymers of the invention, such as for imaging...
US20160374601 OXYGEN SENSORS  
Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
US20160235865 PROSTATE-SPECIFIC MEMBRANE ANTIGEN-TARGETED PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY  
Urea-based photosensitizers, which target prostate-specific membrane antigen (PSMA) for imaging and targeted therapy of PSMA-expressing tumors and cancers are disclosed.
US20160220703 DIAGNOSING AND TREATING CANCER  
The invention relates to compositions and methods for diagnosing as well as treating cancer diseases associated with choline kinase (ChoK). Specifically, the invention relates to a composition...
US20160176886 BACTERIOCHLORIN IMIDES  
Compound of Formula I: are described, along with compositions containing the same and methods of use thereof.
US20160031909 PORPHYRAZINE OPTICAL AND DUAL OPTICAL/ MR CONTRAST AND THERAPEUTIC AGENTS  
Porphyrazines capable of localizing in a tumor of a mammal are disclosed. The porphyrazines are used in methods of imaging a tumor and in methods of treating tumors, either alone or in combination...
US20150343084 THERAPEUTIC AND DIAGNOSTIC PROBES  
The present invention provides compositions and methods of use of nanoparticle-based probes for in vivo imaging and therapy. The probes can be used to track diseased target cells by non-invasive...
US20150315202 CHLORIN DERIVATIVE USEFUL IN PHOTODYNAMIC THERAPY AND DIAGNOSIS  
The present invention relates to chlorin e4 sodium and a process for its preparation. Chlorin e4 sodium is suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic...

Matches 1 - 41 out of 41