Matches 1 - 50 out of 113 1 2 3 >


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US20150079003 Methods and Compositions for Cancer Diagnosis  
The present invention provides reagents and methods for detecting cancer precancerous lesions in a patient.
US20120109045 Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules  
The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical...
US20130101521 METHODS DEVICES AND SYSTEMS OF PREPARING TARGETED MICROBUBBLE SHELLS  
Targeted microbubbles are generated by post-labeling buried ligand microbubbles. According to embodiments, buried ligand microbubbles are created with steric brushes protecting functionalized...
US20120034170 Nanobubbles Useful As An Ultrasonic Contrast Agent For The Lymphatic System  
A composition is provided accompanying nanoparticles having diameters in the range of about 100 to 800 nanometers with hollow cores and outer shells with mechanical properties such that they...
US20110165088 NANOBUBBLES USEFUL AS AN ULTRASONIC CONTRAST AGENT FOR LYMPHATIC SYSTEM  
A composition is provided accompanying nonoparticles having diameters in the range of about 100 to 800 nanometers with hollow cores and outer shells with mechanical properties such that they...
US20130156706 TARGETED GAS-FILLED MICROVESICLES  
Gas-filled microvesicles associated with a polypeptide comprising a sequence of amino acids, said sequence exhibiting binding affinity for selectins, particularly p-selectin. The gas-filled...
US20130101520 ULTRASOUND CONTRAST AGENTS AND METHODS OF MAKING AND USING THEM  
The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents.
US20120093732 ULTRASOUND CONTRAST AGENTS AND METHODS OF MAKING AND USING THEM  
The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents.
US20140363381 METHOD, COMPOUNDS AND PREPARATIONS FOR THE IDENTIFICATION OF SENTINEL LYMPH NODES  
The present invention relates to methods for the identification of a sentinel lymph node and to compounds and preparations used in said methods.
US20140257100 Porphyrin Microbubbles  
The present invention relates to a microbubble comprising a monolayer of porphyrin-phospholipid conjugate, said microbubble having encapsulated therein, and to the use of said microbubble in...
US20130183234 Compositions Useful for Target, Detection, Imaging and Treatment, and Methods of Production and Use Thereof  
Compositions useful for target detection, imaging and treatment, as well as methods of production and use thereof, are disclosed herein.
US20140147390 STABILIZED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS  
A stabilized nanobubble can include a membrane that defines at least one internal void, which includes at least one gas. The membrane can include at least one lipid and at least one nonionic...
US20110150778 Assembly of Gas-Filled Microvesicle With Active Component For Contrast Imaging  
Assembly comprising a gas-filled microvesicle and a structural entity which is capable to associate through an electrostatic interaction to the outer surface of said microvesicle (microvesicle...
US20070286809 OXYGEN THERAPY WITH ULTRASOUND  
A treatment is described for delivering oxygen to tissue, especially hypoxic tissue. A medium saturated with gas is delivered to the tissue. Dissolved gas is transferred from the medium to the...
US20140205545 MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS  
The invention provides compositions and methods for therapeutic and diagnostic applications.
US20060263302 Systemic oxygenation via gastric perfusion with perfluorocarbon (PFC)  
The present invention is based on the discovery that an increase in systemic oxygenation can be achieved by gastric perfusion of an oxygenated liquid, e.g., perfluorocarbon. Accordingly, the...
US20130129635 POLYMERIZED SHELL LIPID MICROBUBBLES AND USES THEREOF  
The present invention relates to the fabrication and use of microbubbles. In some embodiments, the invention provides for the fabrication and use of polymerized shell lipid microbubbles (PSMs)....
US20140140934 LIVER TUMOR-TARGETING ULTRASOUND CONTRAST AGENT AND METHOD FOR PREPARING THE SAME  
Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be...
US20140288421 GAS VESICLE ULTRASOUND CONTRAST AGENTS AND METHODS OF USING THE SAME  
Provided are ultrasound imaging methods that include administering to a subject a contrast agent that includes a plurality of collapsible gas vesicles, obtaining ultrasound data of a target site...
US20130022551 DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS  
Provided herein are novel compositions comprising DEspR-specific antagonists and agonists, and methods of their use in a variety of therapeutic applications. The compositions comprising the...
US20150202335 TARGETED MOLECULAR IMAGING PROBE AND METHOD FOR IN VIVO MOLECULAR IMAGING  
Disclosed is a targeted molecular imaging probe consisting of a signal component, a component with a targeted affinity to Cx43 and a linker. The biochemical variation characteristic of connexin43...
US20060013772 Method and device to recover diagnostic and therapeutic agents  
The invention relates to a method and device for recovering therapeutic and diagnostic agents from the venous outflow of a tissue or organ. A method for recovering an agent includes inserting a...
US20150023881 CONTRAST AGENT FOR COMBINED PHOTOACOUSTIC AND ULTRASOUND IMAGING  
A microbubble is used as a multi-modality contrast agent for photoacoustic imaging and ultrasound imaging. A method of preparing improved microbubbles that are used as a multi-modality contrast...
US20110300078 ISOLATION OF MICROBUBBLES OF SELECTED SIZE RANGE FROM POLYDISPERSE MICROBUBBLES  
In one aspect of the disclosed subject matter, a method for isolating target microbubbles having a predetermined size range from polydisperse microbubbles is disclosed. The method includes...
US20050013780 Hollow microspheres with controlled fragility for medical use  
A composition for ultrasonic imaging is described having a microparticle population of controlled fragility. A method of using such composition for imaging a fluid filled cavity, vessel or tissue...
US20100008863 TARGETING AND THERAPEUTIC COMPOUNDS AND GAS-FILLED MICROVESICLES COMPRISING SAID COMPOUNDS  
New targeting or therapeutic compounds which can be incorporated into a composition of gas-filled microvesicles. The invention further relates to gas-filled microvesicles for diagnostic and/or...
US20080269668 Medical Microbubble Generation  
Medical apparatus and processes controllably generate medically useful micro or nano bubbles of medically desirable and controllably selectable size, size distribution, homogeneity and...
US20050180922 Block co-polymer worm micelles and methods of use therefor  
Provided are worm-like micelles, capable of encapsulating at least one encapsulant, wherein each worm-like micelle comprises one or more wholly synthetic, polymeric, super-amphiphilic molecules...
US20070269381 ULTRASOUND CONTRAST AGENT DOSAGE FORMULATION  
Clinical studies have been conducted and specific dosage formulations developed using polymeric microparticles having incorporated therein perfluorocarbon gases that provide significantly enhanced...
US20150250903 MOLECULAR IMAGING CONTRAST AGENTS AND USES THEREOF  
Compositions and methods for molecular imaging of selectins are disclosed. Specifically, compositions comprising medical imaging contrast-producing agents associated with the extracellular domain...
US20100158813 MICROBUBBLES AS DRUG DELIVERY DEVICE  
A method of making PVA microbubbles including a functionalisation step in which PVA polymeric chains are functionalised at their ends with aldehyde groups, and a subsequent cross-linking step, in...
US20100196284 Ultrasound Imaging with Targeted Microbubbles  
Compositions and methods for detecting various disorders with targeted microbubbles are disclosed. Specifically, microbubbles comprising glycoprotein Ib (GPIb), ligands for VCAM-1, and ligands for...
US20120148502 Carbohydrate-Mediated Tumor Targeting  
Tumors can be selectively targeted via compounds provided herein according to the formula, or a pharmaceutically acceptable salt thereof, wherein RA and RB are as defined herein. Tumors can be...
US20050025710 Reconstitutable formulation and aqueous suspension of gas-filled microvesicles for diagnostic imaging  
The invention relates to a formulation comprising a dry material (e.g. lyophilised or spray dried) comprising at least one film forming surfactant and a gas or a gas mixture usable in diagnostic...
US20100158815 Biological Cell Tracking With Ultrasound  
This invention addresses the clinical problem of how to optimize biological cell based therapies, such as stem cell therapy. Currently, cell therapies administered by intravenous, intra-arterial,...
US20080095716 Use in the Medical, Diagnostic and Phlebological Field of a Mixture of Sterile and Physiologically Acceptable Purposes  
The present invention relates to a mixture of sterile and apyrogenic gases based on CO2 and O2 suitable for producing microbubbles which can be used in the medical, phlebological and diagnostic...
US20070183976 Composition for ultrasound therapy and pharmaceutical liquid composition containing the same  
The present invention provides pharmaceutical liquid compositions, comprising a liquid, a prodrug, and a large quantity of microbubbles formed by a gas dispersed in the liquid, the microbubbles...
US20070071685 Gas-filled microvesicle assembly for contrast imaging  
Assembly comprising a gas-filled microvesicle and a structural entity which is capable to associate through an electrostatic interaction to the outer surface of said microvesicle (microvesicle...
US20140377186 MICROBUBBLE ULTRASOUND CONTRAST AGENT FOR EXTERNAL USE  
A microbubble ultrasound contrast agent for external use is provided. The microbubble ultrasound contrast agent applied externally can safely and efficiently enhance the permeation and absorption...
US20140276363 Sonochemical Induction of ABCA1 Expression and Compositions Therefor  
The present invention provides compositions useful for transfecting cells (e.g., liver cells) to express ABCA1. The compositions described herein comprise a pharmaceutically acceptable aqueous...
US20080181853 NANOBUBBLES USEFUL AS AN ULTRASONIC CONTRAST AGENT FOR THE LYMPHATIC SYSTEM  
A composition is provided accompanying nanoparticles having diameters in the range of about 100 to 800 nanometers with hollow cores and outer shells with mechanical properties such that they...
US20080008658 Contrast Agent Formulations for the Visualization of the Lymphatic System  
The present invention relates to the field of diagnostic imaging and provides compositions of ultrasound contrast agents, particularly gas-filled microvesicles suspensions, in combination with...
US20080279783 ISOLATED NANOCAPSULE POPULATIONS AND SURFACTANT-STABILIZED MICROCAPSULES AND NANOCAPSULES FOR DIAGNOSTIC IMAGING AND DRUG DELIVERY AND METHODS FOR THEIR PRODUCTION  
A method for producing surfactant-stabilized microcapsules or nanocapsules including the steps of (a) preparing a suspension comprising a non-ionic sorbitan detergent and a salt in phosphate...
US20090162293 METHODS AND COMPOSITIONS FOR ULTRASOUND IMAGING OF APOPTOSIS  
In some aspects, there are provided compositions and kits including annexin coupled to ultrasound contrast particles as well as methods utilizing these particles for diagnosis and treatment of...
US20130101522 Ultrasound Contrast Agents And Process For The Preparation Thereof  
Injectable aqueous suspension of microbubbles filled with a biocompatible gas and a method of preparation thereof. At least 10% of the total volume of gas contained in the microbubbles is...
US20110236320 Ultrasound Contrast Agents And Process For The Preparation Thereof  
Injectable aqueous suspension of microbubbles filled with a biocompatible gas and a method of preparation thereof. At least 10% of the total volume of gas contained in the microbubbles is...
US20090087384 MEDICINE AND METHOD FOR TREATMENT OF PROSTATE CANCER  
The invention concerns a medicine for treatment of prostate cancer and a corresponding treatment method. The medicine can be supplied to a prostate tumor through the bloodstream, contains an...
US20130266518 Methods and Compositions for Using Bleomycin-Derivatized Microbubbles  
Methods and compositions for using tumor targeting compounds bound to microbubbles to facilitate drug delivery and diagnostic imaging at tumor sites.
US20110293530 Methods and Compositions for Using Bleomycin-Derivatized Microbubbles  
Methods and compositions for using tumor targeting compounds bound to microbubbles to facilitate drug delivery and diagnostic imaging at tumor sites.
US20150125399 PREPARATION METHOD OF ORGANIC MICROBUBBLE COMPLEX PARTICLE, ORGANIC MICROBUBBLE COMPLEX PARTICLE, AND ULTRASOUND CONTRAST AGENT  
This disclosure relates to a method for preparing organic microbubble complex particles including sonicating an aqueous solution including a graphene compound and an amphiphilic material in the...

Matches 1 - 50 out of 113 1 2 3 >