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US20150125401 SMALL MAGNETITE THERAPEUTICS AND METHODS OF USE THEREOF  
The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
US20130245357 Magnetic Nanoparticle Formulations, Methods for Making Such Formulations, and Methods for their Use  
The present invention provides derivatized magnetic nanoparticles, methods for making such nanoparticles, and methods for their use.
US20130149539 TUNED MULTIFUNCTIONAL MAGNETIC NANOPARTICLES FOR BIOMEDICINE  
Magnetic nanoparticles and related devices and methods are described. Compositions and methods can include magnetic nanoparticles having a narrow size distribution for use in diagnostics and...
US20140161734 HYDROPHILIC NANOPARTICLES SURFACE-MODIFIED WITH MONOSACCHARIDE PHOSPHATE OR MONOSACCHARIDE PHOSPHATE DERIVATIVES, ITS COLLOIDAL SOLUTION AND USE THEREOF  
Disclosed are a composition including hydrophilic nanoparticles that have a monosaccharide-phosphate or a derivative thereof adhered to the surface thereof, a colloidal solution of the composition...
US20130030282 SYNTHESIS AND CHARACTERIZATION OF NEAR IR FLUORESCENT MAGNETIC AND NON-MAGNETIC ALBUMIN NANOPARTICLES FOR BIOMEDICAL APPLICATIONS  
The present invention discloses Near Infrared (NIR) fluorescent albumin nanoparticles having a structure selected from a core structure or a core-shell structure. Also disclosed are a process of...
US20140241996 THERAPEUTIC NANOPARTICLES AND METHODS OF USE THEREOF  
Provided herein are therapeutic nanoparticles having a diameter of between 10 nm to 30 nm, and containing a polymer coating, and a nucleic acid containing a sequence complementary to a sequence...
US20130045161 METHODS AND COMPOSITIONS FOR TARGETED IMAGING  
A new approach to targeting imaging agents to macrophage-rich sites of interest is disclosed. Compositions of the invention are rHDL and HDL-like liposomal compositions, protein constituents of...
US20150065858 CORE-SATELLITE NANOCOMPOSITES FOR MRI AND PHOTOTHERMAL THERAPY  
The present invention provides methods, compositions, systems, and kits comprising core-satellite nanocomposites useful for photothermal and/or MRI applications (e.g., tumor treatment and/or...
US20110085987 FOLIC ACID-MEDIATED MAGNETIC NANOPARTICLE CLUSTERS FOR COMBINED TARGETING, DIAGNOSIS, AND THERAPY APPLICATIONS  
The preparation method of the magnetic nanoparticle (MNP) includes steps of: (a) reacting folic acid (FA) with Pluronic F127 (PF127) to form FA-PF127; (b) reacting poly(acrylic acid) (PAA) with...
US20130121927 DETECTION, MEASUREMENT, AND IMAGING OF CELLS SUCH AS CANCER AND OTHER BIOLOGIC SUBSTANCES USING TARGETED NANOPARTICLES AND MAGNETIC PROPERTIES THEREOF  
The present invention provides methods and apparatuses for detecting, measuring, or locating cells or substances present in even very low concentrations in vivo in subjects, using targeted...
US20140170078 MAGNETIC RESONANCE IMAGING T2 CONTRAST MEDIUM FOR CELL CONTRASTING, AND METHOD FOR MANUFACTURING SAME  
The invention relates to a magnetic resonance imaging T2 contrast medium (agent) for cell contrasting, and to a method for manufacturing the same. The magnetic resonance imaging T2 contrast agent...
US20110059025 IN VIVO IMAGING  
The present invention provides an imaging method for obtaining an image of a patient by means of a contrast agent wherein the method comprises subjecting the patient to an imaging method for which...
US20120269737 POLYMER COATED FERRITE FINE PARTICLES AND METHOD FOR PREPARING POLYMER COATED FERRITE FINE PARTICLES  
[Object] To provide a polymer coated ferrite fine particles being possible to control a particle size uniformly while having high aqueous dispersibility and preferred biomolecule immobilization...
US20140314679 Hypoosmotic Solutions for Lymph Node Detection  
Provided are compositions for rapid detection of lymph nodes. The compositions include magnetic particles, such as iron oxide, and a solute present in an amount that results in a hypoosomotic...
US20120004531 Innately Multimodal Nanoparticles  
A gold-coated iron oxide nanoparticle, method of making thereof, and method of using thereof is disclosed. The nanoparticle is substantially toxin free (making it clinically applicable), easily...
US20150258224 LOADABLE POLYMERIC PARTICLES FOR ENHANCED IMAGING IN CLINICAL APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME  
Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives thereof which may be present throughout...
US20120114564 MRI T1 CONTRASTING AGENT COMPRISING MANGANESE OXIDE NANOPARTICLE  
The present invention relates to the use of and method for using MnO nanoparticles as MRI T1 contrasting agents which reduces T1 of tissue. More specifically, the present invention is directed to...
US20120282186 TEMPLATED NANOCONJUGATES  
The present disclosure is directed to compositions comprising templated nanoconjugates and methods of their use.
US20100310474 PROTEIN CAGES FOR THE DELIVERY OF MEDICAL IMAGING AND THERAPEUTIC AGENTS  
The present invention is directed to novel compositions and methods utilizing delivery agents comprising protein cages, medical imaging agents and therapeutic agents.
US20150079006 IRON OXIDE NANOCOMPOSITE, MAGNETIC RESONANCE IMAGING T2 CONTRAST MEDIUM COMPRISING SAME, AND METHOD FOR MANUFACTURING SAME  
The present invention relates to iron oxide nanocomposite, magnetic resonance imaging T2 contrast medium comprising same, and method for manufacturing same. More particularly, the present...
US20140023594 MRI CONTRAST AGENT FOR LYMPHOGRAPHY BASED ON IRON OXIDE NANOPARTICLES AND METHOD FOR IMAGING LYMPH NODE USING THE SAME  
Provided are a contrast agent for contrast imaging lymph node, which includes iron oxide nanoparticles dispersed and stabilized in an aqueous medium by a mussel adhesive protein-mimetic copolymer,...
US20110129417 ADMINISTRABLE COMPOSITIONS  
The present invention relates to a composition suitable for administration to a subject, the composition comprising pharmacologically acceptable particulate material dispersed throughout a...
US20150132231 SURFACE FUNCTIONALIZATION OF SUPERPARAMAGNETIC NANOPARTICLES FOR BIOLOGICAL ENCAPSIDATION  
Method and compositions are provided that relate to superparamagnetic nanoparticles, including IONP with small diameter and high transverse relaxivity, that are stable in an aqueous environment....
US20130330280 Aqueous Method of Making Magnetic Iron Oxide Nanoparticles  
The invention discloses an aqueous method of making polymer coated superparamagnetic nanoparticles. Nanoparticles made by the method are included in the invention.
US20130323182 METHOD OF PREPARING IRON OXIDE NANOPARTICLES COATED WITH HYDROPHILIC MATERIAL, AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT USING THE SAME  
The present invention relates to a method of preparing biocompatible iron oxide nanoparticles by coating iron oxide nanoparticles having improved magnetism via annealing treatment using salt...
US20130183249 Stimulus Sensitive Magnetic Nanocomposite Using Pyrene Polymer, and Contrast Medium Composition Containing the Nanocomposite  
Provided are a stimuli-sensitive magnetic nanocomposite using a pyrene-conjugated polymer and a method of preparing the same. Particularly, the stimuli-sensitive magnetic nanocomposite includes...
US20120134932 Manganese-Oxo Clusters as Contrast Agents for Magnetic Resonance Imaging  
Nanoparticles for use as magnetic resonance imaging contrast agents are described. The nanoparticles are made up of a polymeric support and a manganese-oxo or manganses-iron-oxo cluster having...
US20140369939 COMPOSITIONS FOR DETECTING ANALYTES BY MAGNETIC RESONANCE IMAGING  
Injectable compositions for the MRI detection of an analyte selected from the group consisting of reactive oxygen species, proteases and enzymes, comprising a) a matrix material based on a...
US20050031544 Receptor mediated nanoscale copolymer assemblies for diagnostic imaging and therapeutic management of hyperlipidemia and infectious diseases  
This invention relates to a method and system for improving diagnostic imaging and/or delivering therapeutically active agents for control of hyperlipidemia and infectious diseases (bacterial or...
US20130164223 IRON OXIDE NANOCAPSULES, METHOD OF MANUFACTURING THE SAME, AND MRI CONTRAST AGENT USING THE SAME  
Provided are iron oxide nanocapsules for an MRI contrast agent having high contrast, in which a plurality of iron oxide nanoparticles having a hydrophobic ligand attached thereto are encapsulated...
US20130344004 MATRIX METALLOPROTEASE TARGETING NUCLEIC ACIDS  
A reporter conjugate for non-invasive detection (e.g., imaging) of matrix metalloprotease (MMP) gene expression in vivo is disclosed. The conjugate includes a targeting nucleic acid linked to a...
US20100166669 METHODS OF IMAGING INFLAMMATION IN PANCREATIC ISLETS  
Described are non-invasive methods for imaging pancreatic inflammation in living mammals using Magnetic Nanoparticle Probes (MNPs).
US20090035223 BIOMIMETIC IRON-OXIDE-CONTAINING LIPOPROTEIN AND RELATED MATERIALS  
An engineered lipoprotein including (a) a core particle or a plurality of core particles, each core particle has (i) an inner part comprising a hydrophilic active agent and a hydrophilic portion...
US20130195766 ULTRAFINE NANOPARTICLES COMPRISING A FUNCTIONALIZED POLYORGANOSILOXANE MATRIX AND INCLUDING METAL COMPLEXES; METHOD FOR OBTAINING SAME AND USES THEREOF IN MEDICAL IMAGING AND/OR THERAPY  
The invention relates to novel biocompatible hybrid nanoparticles of very small size, useful in particular for diagnostics and/or therapy. The purpose of the invention is to offer novel...
US20090041674 TARGETED IRON OXIDE NANPARTICLES  
Iron oxide nanoparticles comprising functional groups of the formula —X—NH2 on the outer surface of said nanoparticles, wherein X is selected from O, NR, NH or S, where R is C1-7 alkyl and...
US20150224212 FERRITIN-BASED TUMOR TARGETING AGENT, AND IMAGING AND TREATMENT METHODS  
An MRI contrast material includes tumor-targeting metal-loaded ferritin nanoparticles constructed with genetically modified ferritin coupled to a target-specific agent. Ferritin derived from...
US20150071863 LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF  
The invention relates to compositions of DOTA derivative compounds, lanthanoid-DOTA derivative molecular complex, and lanthanoid-complex encapsulated solid lipid particles or capsules, and methods...
US20120294809 LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF  
The invention relates to compositions of DOTA derivative compounds, lanthanoid-DOTA derivative molecular complex, and lanthanoid-complex encapsulated solid lipid particles or capsules, and methods...
US20120020894 Production of Targeted MRI Probes by Biocompatible Coupling of Macromolecules with Charged Nanoparticles  
The present invention relates to the production of marker particles, which are especially useful for target-specific molecular magnetic resonance imaging (MRI), using charged iron oxide...
US20150093335 CELL-TARGETED MAGNETIC NANO-MATERIAL AND BIOMEDICAL USES THEREOF  
Disclosed are a cell-targeted nano-material and biomedical uses thereof. The magnetic nano-material can bind with specificity to iron protein receptors having high expression on the surface of...
US20100015060 Magnetic Nanoparticles for the Application in Hyperthermia, Preparation Thereof and Use in Constructs Having a Pharmacological Application  
There are described nanoparticles of magnetic metal oxides employable in constructs consisting in polymer particles possibly also incorporating pharmacologically active substances.
US20140050670 MULTIFUNCTIONAL NANOPARTICLES  
The invention provides a nanoparticle for delivery of therapeutic agents, comprising a polymeric nanosphere and one or more detection agents, said detection agents for use in detecting the...
US20110212032 POLYMER PARTICLES FOR NIR/MR BIMODAL MOLECULAR IMAGING AND METHOD FOR PREPARING THE SAME  
The present invention relates to polymer particles showing magnetic properties and fluorescent properties simultaneously and a preparation method thereof More specifically, relates to polymer...
US20130261710 BLOCK COPOLYMER (BCP) ENCAPSULATED NANOPARTICLES AND METHODS OF USE THEREOF  
This invention provides block copolymer (BCP) encapsulated nanoparticles. The BCP-encapsulated nanoparticles are used in methods for targeting a tumor, in methods of imaging a tumor and in methods...
US20150258222 Magnetic Nanoparticles  
A magnetic nanoparticle includes a magnetic core and a superparamagnetic outer shell, in which the outer shell enhances magnetic properties of the nanoparticle. The enhanced magnetic properties of...
US20150004103 Tumorspecific PET/MR(T1), PET/MR(T2) and PET/CT contrast agent  
New types of nanoparticle-based dual-modality positron emission tomography/magnetic resonance imaging (PET/MRI) and positron emission tomography/computed tomography (PET/CT) tumorspecific contrast...
US20100254914 NANOWORMS FOR IN VIVO TUMOR TARGETING  
The disclosure provides elongated nanostructures useful for biological imaging and measurement. More particularly the disclosure provides nanoworms having an increased bioavailability compared to...
US20070286810 Nanoparticles comprising lanthanide chelates  
The invention concerns a method for preparing a particle comprising a lanthanide chelate, comprising polymerizing a lanthanide chelate derivative with one or more monomers, wherein the lanthanide...
US20080241073 Polymeric Micelle Type Mri Imaging Agent  
A contrast agent for magnetic resonance imaging which stably circulates in the blood for a long period and which targets solid tumors, with which clear images of cancers may be obtained is...
US20090155169 Glyco-molecular imaging method for grade classification of liver fibrosis and its glyco-molecular imaging agent thereof  
The invention discloses one glyco-molecular imaging method for grade classification of liver fibrosis and its glyco-molecular imaging agent. The agent combining with glyco-molecular imaging method...

Matches 1 - 50 out of 104 1 2 3 >