Matches 1 - 38 out of 38


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US20110286937 SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME  
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present...
US20130230457 Thermosensitive Nanoparticle Formulations and Method of Making The Same  
The present invention relates to a formulation of thermosensitive liposomes, and more specifically to a formulation of liposomes comprising phospholipids and a surface active agent, wherein the...
US20070196284 Liposomal assembly for therapeutic and/or diagnostic use  
Composition for diagnostic or therapeutic use which comprises an assembly comprising an active agent. The assembly comprises a liposome and a plurality of micellar components associated thereto,...
US20110274625 Liposomal Composition for Convection-Enhanced Delivery to the Central Nervous Centre  
Convection-enhanced delivery (CED) is used as a method to deliver a direct infusion of therapeutic agents to the central nervous centre thus circumventing the blood-blood barrier. A non-PEGylated...
US20120141381 Methods For Loading Contrast Agents Into A Liposome  
The invention comprises compositions and methods for loading both magnetic resonance contrast agents and therapeutic agents into liposomes, such as low temperature sensitive liposomes (LTSLs). In...
US20140178296 TUMOR-TARGETED NANODELIVERY SYSTEMS TO IMPROVE EARLY MRI DETECTION OF CANCER  
The present invention is in the fields of drug delivery, cancer treatment and diagnosis and pharmaceuticals. This invention provides a method of making antibody- or antibody fragment-targeted...
US20130183234 Compositions Useful for Target, Detection, Imaging and Treatment, and Methods of Production and Use Thereof  
Compositions useful for target detection, imaging and treatment, as well as methods of production and use thereof, are disclosed herein.
US20140186268 Oxide Ferrimagnetics with Spinel Structure Nanoparticles and Iron Oxide Nanoparticles, Biocompatible Aqueous Colloidal Systems Comprising Nanoparticles, Ferriliposomes, and Uses Thereof  
The present invention relates to methods for producing oxide ferrimagnetics with spinel structure and iron oxide nanoparticles by soft mechanochemical synthesis using inorganic salt hydrates,...
US20140161733 BIOMARKER-TARGETING CONTRAST AGENTS AND THEIR USE IN MAGNETIC RESONANCE IMAGING FOR DETECTION OF ATHEROSCLEROTIC PLAQUE  
A composition comprising: a liposome having a bilayer structure, a gadofullerene having a high relaxivity, and an amphiphilic receptor ligand. In the composition, the gadofullerene is embedded in...
US20120100079 STIMULI-RESPONSIVE CARRIERS FOR MPI-GUIDED DRUG DELIVERY  
The present invention relates to a composition comprising a shell structure forming a cavity, wherein said shell structure comprises a drug and wherein said composition is associated with at least...
US20130011339 NANOPARTICLE COMPOSITIONS COMPRISING A LIPID BILAYER AND ASSOCIATED METHODS  
Bilayer-nanoparticle compositions comprising a nanoparticle core and a lipid bilayer disposed around the exterior surface of the nanoparticle core are provided. In some embodiments, these...
US20150064115 NEUROPHILIC NANOPARTICLES  
Novel liposomal nanoparticle that has been engineered to be particularly useful for the delivery of compounds to cells found in the peripheral nervous system, and to endothelial cells that form...
US20140044647 MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND USE THEREOF  
The present invention relates to a microvesicle that is derived from nucleated mammalian cells, which are smaller than the nucleated cells. The microvesicles of the present invention can be used...
US20150182627 LIPOSOME INCLUDING ACTIVE INGREDIENT AND IMAGING AGENT AND USE THEREOF  
A stimulus-sensitive liposome with a lipid bilayer comprising a first imaging agent, and an active ingredient and second imaging agent in an interior space defined by the lipid bilayer; a...
US20070036727 Adducts between magnetic resonance shift reagents and substrates containing exchangeable protons for "cest" applications  
Disclosed are CEST paramagnetic agents comprising a substrate (SH) containing mobile protons bonded to a para-magnetic chelate (SR) containing a metal selected from iron (11) (high-spin...
US20100158817 T1 MRI TRACKABLE DRUG DELIVERY PARTICLES, USES AND METHODS THEREOF  
The current invention discloses a drug delivery system allowing monitoring of spatial position and drug release, as well as methods and uses thereof. More particularly, the drug delivery system...
US20070189973 Contrast medium comprising liposomes containing hydrophobic chelate compound  
A liposome containing a hydrophobic chelate compound as a membrane component, and an MRI contrast medium containing the liposome for use in imaging of, preferably, a vascular disease. An MRI...
US20090214441 Lipophilic Chelates and Their Use in Imaging  
The invention relates to chelate compounds which can be used in MRI, the chelates being intended to be conveyed by lipophilic transporters, such as lipid nanoparticles or liposomes. The invention...
US20130142729 Anti-CD74 Immunoconjugates and Methods of Use  
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more...
US20130129636 Novel Liposome Nanoparticles for Tumor Magnetic Resonance Imaging  
The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium(III)2-{4,7-bis-carboxymethyl-10-[(N,N-distearyla midomethyl-N′-amido-methyl]-1,4,7,10-tetra-azacyclododec-1-y l}-ac...
US20080014150 Compositions and method for treating precancerous virus infection and prevention of cancer  
An anti-cancer composition having biocompatible materials, which can selectively exploit chemical variations between normal cells and cancer cells to inhibit or prevent the proliferation of...
US20100111876 USE OF METAL NANOPARTICLES IN THE DIAGNOSIS OF ALZHEIMER'S DISEASE  
The invention relates to the use of metal nanoparticles for the preparation of a composition for diagnosing Alzheimer's disease by MRI.
US20090142273 Activatable cest MRI agent  
A chemical exchange saturation transfer (CEST) contrast agent is provided. One embodiment includes a ligand and a functional group linked to the ligand. The functional group has a hydrogen...
US20070140973 CONTRAST AGENTS FOR MYOCARDIUM PERFUSION IMAGING  
The present invention is directed, in part, to compounds and methods for diagnostic imaging, comprising administering to a patient a contrast agent which has an overall negative charge.
US20090022668 Mri contrast agents endowed with concentration independent responsiveness  
The present invention relates to a method for the in vivo, ex vivo, or in vitro determination of physical or chemical parameters of diagnostic interest by use of a slow tumbling paramagnetic agent...
US20050112065 Remote detection of substance delivery to cells  
The present invention provides for the development of endocytosis-sensitive probes, and a remote method for measuring cellular endocytosis. These probes are based on the reduced water permeability...
US20140086846 CONTRAST ENHANCEMENT AGENTS AND METHOD OF USE THEREOF  
A contrast agent composition and a method of diagnostic imaging are provided. The composition comprises a pharmaceutically acceptable carrier and a metal-complex comprising a ligand having...
US20090274630 RED BLOOD CELL-DERIVED VESICLES AS A NANOPARTICLE DRUG DELIVERY SYSTEM  
Red blood cell-derived vesicles (RDV) as a nanoparticle drug delivery system. The RDV are smaller than one micrometer, capable of encapsulating and delivering an exogenous substance into cells....
US20100061938 MRI TRACKABLE DRUG DELIVERY PARTICLES, USES AND METHODS THEREOF  
The current invention discloses a drug delivery system allowing monitoring of spatial position and drug release, as well as methods and uses thereof. More particularly, the drug delivery system...
US20100254913 NON-SPHERICAL CONTRAST AGENTS FOR CEST MRI BASED ON BULK MAGNETIC SUSCEPTIBILITY EFFECT  
In magnetic resonance imaging (MRI) based on chemical exchange-dependent saturation transfer (CEST), a novel carrier for CEST contrast agents is provided. The carrier is non-spherical and...
US20070292354 Contrast Agents Encapsulating Systems for Cest Imaging  
The present invention concerns a contrast agent compound for CEST imaging wherein said contrast agent comprises a proton pool encapsulating system that contains a pool of water mobile shifted protons.
US20090191131 USE OF PARTICULATE CONTRAST AGENTS IN DIAGNOSTIC IMAGING FOR STUDYING PHYSIOLOGICAL PARAMATERS  
The present invention relates to a method of imaging of an animate human or non-human animal body, which method comprises: administering parenterally to said body a particulate material comprising...
US20090311194 METHODS AND COMPOSITIONS FOR THE PRODUCTION AND USE OF MAGNETOSOMES  
Methods and compositions for using magnetosomes as cellular contrast agents and markers for magnetic resonance imaging are provided. Certain methods involve synthesizing magnetosomes in a cell as...
US20170080111 MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES  
Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The...
US20160136306 SYSTEMS AND METHODS OF DETECTING INTERSTITIAL CYSTITIS  
The invention provides systems and methods for providing a diagnostic examination to a patient, including, but not limited to a determination of the permeability of a patients' body cavity.
US20160101197 MRI Imaging of Amyloid Plaque Using Liposomes  
Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The...
US20160038616 METHOD OF MONITORING THE RELEASE FROM LIPOSOMES OF A PRODUCT OF INTEREST USING SUPERPARAMAGNETIC NANOPARTICLES  
The present application relates to a method of monitoring the membrane permeabilization of liposome and the incidental release of a compound of interest.
US20160022842 FORMATION AND USES OF EUROPIUM  
An MRI contrast composition includes a liposome and a europium metal complex disposed within the liposome. The europium metal complex includes a europium metal ion and a multi-dentate ligand...

Matches 1 - 38 out of 38