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US20110182995 MEDICAL AND DENTAL BIOMATERIAL AND METHOD OF USE FOR THE SAME  
The embodiments herein provide a dental and medical biomaterial and its use for sealing and/or filling the tooth and bone cavities. In the embodiments herein, the calcium salt, calcium oxide,...
US20120282300 PROTEIN BIOMATERIALS AND BIOCOACERVATES AND METHODS OF MAKING AND USING THEREOF  
The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention...
US20150252415 ARID1B AND NEUROBLASTOMA  
Neuroblastomas are tumors of peripheral sympathetic neurons and are the most common solid tumor in children. We performed whole-genome sequencing (6 cases), exome sequencing (16 cases),...
US20120282217 FOOT AND MOUTH DISEASE VIRUS (FMDV) CONSENSUS PROTEINS, CODING SEQUENCES THEREFOR AND VACCINES MADE THEREFROM  
Provided herein is a nucleic acid comprising consensus amino acid sequence of foot-and-mouth disease FMDV VP1-4 coat proteins of FMDV subtypes A, Asia 1, C, O, SAT1, SAT2, and SAT3 as well as...
US20110195103 COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION CONTAINING PSEUDOALTEROMONAS FERMENT EXTRACT  
Cosmetic or dermopharmaceutical compositions containing Pseudoalteromonas ferment extract for the treatment and/or care of the skin, scalp and/or nails, preferably to improve the barrier function...
US20110097367 MONOLITHIC IN-SITU CROSS-LINKED ALGINATE IMPLANTS  
A method of making and using a monolithic alginate implant is described. The implant is formed by providing an uncrosslinked, highly pure and high molecular weight alginate solution and injecting...
US20120328561 METHOD FOR TREATMENT OF INFLAMMATORY GASTROINTESTINAL DISORDERS  
Providing a new method of treating inflammatory gastrointestinal disorders and a food product for the prevention or improvement of inflammatory gastrointestinal disorders. Prevention or treatment...
US20110038832 METHOD FOR TREATMENT OF MACULAR DEGENERATION USING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOISOINDOLINE-1,3-DIONE  
Provided herein are methods of treating macular degeneration, which comprises administering to a patient in need thereof a therapeutically effective amount of...
US20140234252 Composition and Methods for the Treatment of Degenerative Retinal Conditions  
The present invention is directed to compositions and methods for the treatment of degenerative retinal conditions. According to a general aspect, the present invention is directed to inflammatory...
US20140308239 CHIMERIC CYTOKINE FORMULATIONS FOR OCULAR DELIVERY  
Featured herein are vehicle formulations and formulations containing a chimeric cytokine designed for e.g., ocular delivery.
US20110206759 CCR7 LIGAND DELIVERY AND CO-DELIVERY IN IMMUNOTHERAPY  
Chemokines may be administered to a patient for immunotolerization. Chemokines include CCL19 and CCL21. Materials and methods for accomplishing tolerization and described.
US20140099270 Method of Use and Preparation of HSA Fusion Protein Composition for Skincare  
The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and...
US20150218649 BIOMARKER ASSOCIATED WITH RISK OF MELANOMA REOCCURRENCE  
The present invention provides a method of predicting the risk of reoccurrence of melanoma in a patient from whom melanoma tissue was previously removed which comprises the following: a. obtaining...
US20140010781 SIRNA AGAINST CBL-B AND OPTIONALLY IL-2 AND IL-12 FOR USE IN THE TREATMENT OF CANCER  
The invention relates to a method for the immune activation of NK cells by the reduction or inhibition of the Cbl-b function in said cells. This stimulates the congenital immune system and thus...
US20120244115 TREATING NON-HEMATOPOIETIC CANCER WITH INTERLEUKIN 6  
Use of IL-6 for treating non-hematopoietic cancers, e.g., gp130-negative cancers. Also disclosed is a method for identifying a cancer patient suitable for the IL-6 treatment.
US20120009143 TREATING NON-HEMATOPOIETIC CANCER WITH INTERLEUKIN 6  
Use of IL-6 for treating non-hematopoietic cancers, e.g., gp130-negative cancers. Also disclosed is a method for identifying a cancer patient suitable for the IL-6 treatment.
US20140093476 METHODS FOR TREATING PAIN  
Methods of treating pain by delivery of anti-inflammatory cytokines, proinflammatory cytokine antagonists, and agents that act to reduce or prevent proinflammatory cytokine actions, to the nervous...
US20130045180 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20120195852 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20140314711 IL-22 POLYPEPTIDES AND IL-22 Fc FUSION PROTEINS AND METHODS OF USE  
The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment...
US20140142718 FLEXIBLE TISSUE MATRIX AND METHODS FOR JOINT REPAIR  
A synthetic, flexible tissue matrix and methods for repairing hyaline cartilage defects in a joint using the flexible tissue matrix are described. The flexible tissue matrix includes a high...
US20130129670 MACROPHAGE ACTIVATING FACTOR FOR USE IN THE TREATMENT OF CHRONIC FATIGUE SYNDROME (CFS) AND CFS-RELATED DISEASES AND DISORDERS  
The present invention relates to Macrophage Activating Factors such as GcMAF and compositions thereof, for use in the treatment of a patient suffering from CFS/ME and/or XMRV infection.
US20100310469 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS  
A method of immunotherapy to treat cancer or a synergistic anti-cancer treatment by administering an effective amount of natural cytokine mixture (NCM), an effective amount of cyclophosphamide...
US20140341843 PURIFIED PROTEINS  
The present invention provides methods and compositions for the preparation and delivery of chimeric cytokine proteins, including cell cultures, methods of purification and purified compositions.
US20150023908 SKIN CREAM  
The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising exosomes and cell culture medium...
US20120100102 CANCER VACCINE  
We disclose a vaccine comprising a pappalysin and vaccine compositions comprising a pappalysin.
US20140186264 EXTRACELLULAR VESICLE-ASSOCIATED PROTEIN MARKERS OF CANCER  
Extracellular vesicle-associated protein biomarkers for use in diagnosing and staging carcinomas, e.g., lung and ovarian cancers.
US20150125384 MODULAR NANODEVICES FOR SMART ADAPTABLE VACCINES  
Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric...
US20110027221 Skincare Composition Comprising HSA Fusion Protein, Preparation Method And Uses Thereof  
The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and...
US20130195794 CANCER VACCINE  
The disclosure relates to a vaccine including at least one adjuvant useful in the prevention and treatment of blood cancers, for example lymphoma, leukaemia or myeloma.
US20120225029 Skin Cream  
The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising cell culture medium conditioned by cells...
US20140178331 METHOD OF TREATING CEREBRAL HEMORRHAGE AND SUBARACHNOID HEMORRHAGE COMPRISING ADMINISTERING METAL CHELATORS TO THE UPPER ONE-THIRD OF THE NASAL CAVITY  
Methods for preconditioning and/or providing neuroprotection to the animal central nervous system against the effects of cerebral hemorrhage and subarachnoid hemorrhage. Therapeutic agents are...
US20110212136 Nanosphere/Microsphere Delivery System for the Treatment of Spinal Cord Injury  
A formulation including injectable biodegradable nanospheres and/or microspheres as a delivery system for chondroitinase ABC (cABC) or a functional derivative of cABC to treat acute and chronic...
US20140112884 COMPOSITION AND METHOD FOR TREATING CANCER  
Pharmaceutical compositions useful as vaccines are described containing a purified surface or excreted protein qualitatively or quantitatively associated with a type of cancer, at least one...
US20120282216 Composition and Method for Treating Cancer  
Pharmaceutical compositions useful as vaccines are described containing a purified surface or excreted protein qualitatively or quantitatively associated with a type of cancer, at least one...
US20140377221 BIOMARKERS AND COMBINATION THERAPIES USING ONCOLYTIC VIRUS AND IMMUNOMODULATION  
The invention disclosed herein describes biomarkers useful for prognosis, selection and monitoring of oncolytic virus therapy for patients with various types of cancer. In particular, the present...
US20140044676 USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS  
Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or...
US20120251488 USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS  
Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or...
US20110177024 USE OF TRUNCATED CYSTEINE IL28 AND IL29 MUTANTS TO TREAT CANCERS AND AUTOIMMUNE DISORDERS  
Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or...
US20130243723 VACCINE IMMUNOTHERAPY  
A composition for treating cancer, including synergistic amounts of a primary cell-derived biologic having the cytokines IL-1, IL-2, IL-6, IL-8, TNF-α, and IFN-γ, and a cancer vaccine having at...
US20120064035 VACCINE IMMUNOTHERAPY  
A composition for treating cancer, including synergistic amounts of a primary cell-derived biologic having the cytokines IL-1, IL-2, IL-6, IL-8, TNF-α, and IFN-γ, and a cancer vaccine having at...
US20120263794 TREATMENT OF EYE DISEASES USING ENCAPSULATED CELLS ENCODING AND SECRETING A NEUROPROTECTIVE FACTOR AND/OR AN ANTI-ANGIOGENIC FACTOR  
The present application refers to cells, e.g. mesenchymal stem cells or mesenchymal stromal cells, or any further suitable cell, encoding and secreting a neuroprotective factor, an anti-angiogenic...
US20130236418 Immunomodulatory Methods and Systems for Treatment and/or Prevention of Aneurysms  
Immunomodulatory agents, T cell, compositions, methods and systems for treating and/or preventing an aneurysm and/or a condition associated thereto in an individual.
US20140205647 METHOD FOR TREATING DEFECTIVE DURA MATER  
Disclosed are an artificial dura mater and manufacturing method thereof. The artificial dura mater includes electrospun layers prepared by electrostatic spinning, at least one of which is a...
US20150203919 METHODS FOR PREDICTING THE SURVIVAL TIME AND TREATMENT RESPONSIVENESS OF A PATIENT SUFFERING FROM A SOLID CANCER WITH A SIGNATURE OF AT LEAST 7 GENES  
The present invention relates to a method for predicting the survival time of a patient suffering from a solid cancer comprising i) determining in a tumor sample obtained from the patient the gene...
US20120164099 USE OF HUMAN PROSTATE CELL LINES IN CANCER TREATMENT  
This invention is concerned with agents for the treatment of primary, metastatic and residual cancer in mammals (including humans) by inducing the immune system of the mammal or human afflicted...
US20130295043 VACCINATION IN ELDERLY PATIENTS  
The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in an elderly patient preferably exhibiting an age of at...
US20150023912 COMBINATIONS OF ALBUMIN-BASED DRUG DELIVERY SYSTEMS  
The present invention relates to a composition comprising at least two different albumin-based drug delivery systems, as well as to a pharmaceutical composition comprising said composition.
US20140044673 Classifying Skin Lesions Using Mass Spectrometry Proteomic Approach  
The present invention provides for a mass spectrometry proteomic approach to distinguishing Spitz nevi from Spitzoid malignant melanoma. Histology directed mass spectral profiling allows for...
US20100310502 Method of treating local infections in mammals  
An effective method is provided for local treatment against localized microbial infection, including abscesses, in skin and soft tissue and elsewhere in mammalian organs. The method employs...