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US20140023705 DOSAGE FORMS FOR ORAL ADMINISTRATION AND METHODS OF TREATMENT USING THE SAME  
The invention relates to dosage forms that provide prolonged therapy. In particular, the invention relates to dosage forms including various pluralities of drug-containing resin particles. The...
US20130022545 DRUG DELIVERY SYSTEM FOR TREATMENT OF LIVER CANCER BASED ON INTERVENTIONAL INJECTION OF TEMPERATURE AND pH-SENSITIVE HYDROGEL  
A drug delivery system for the treatment of liver cancer that is based on interventional injection of a temperature and pH-sensitive hydrogel is provided. The drug delivery system is composed of a...
US20140328933 NOVEL FORMULATIONS AND METHODS  
Nanoparticles comprising VIP and their use in treating, e.g. pulmonary hypertension. Such nanoparticles provide improved delivery of VIP and allow for acute treatment and optionally for sustained...
US20110097406 METHODS AND COMPOSITIONS FOR RETAINING ECM MATERIALS IN HYDROGELS  
The present invention provides cell-laden and/or extracellular matrix material laden hydrogels for use in tissue engineering and methods for producing such hydrogels. In some particular...
US20130243868 NOVEL FORMULATIONS  
Nanoparticles comprising T3 and their use in treating, e.g., cardiac conditions, for example cardiac arrest, are provided. Such nanoparticles provide improved delivery of T3 and allow for acute...
US20120258162 CONTROLLED DELIVERY OF MOLECULES FROM A BIOINTERFACE  
Disclosed are methods and apparatuses for delivery of bioactive molecules. The drug delivery systems include an implantable medical device which significantly reduces or suppresses adverse...
US20110123592 Biomaterials  
The invention relates to a biomaterial having a latent form of a growth factor immobilised thereon, and to a method of producing the biomaterial, comprising immobilising the latent form of the...
US20120093722 SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM  
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active...
US20140363371 TELODENDRIMERS WITH ENHANCED DRUG DELIVERY  
The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include...
US20110318297 SINGLE PROTEIN NANOCAPSULES FOR PROTEIN DELIVERY WITH LONG-TERM EFFECT  
A protein nanocapsule having a single-protein core and a thin polymer shell anchored covalently to the protein core.
US20120020911 MATRIX COMPOSED OF A NATURALLY-OCCURRING PROTEIN BACKBONE CROSS LINKED BY A SYNTHETIC POLYMER AND METHODS OF GENERATING AND USING SAME  
The present invention relates to biodegradable scaffolds composed of a naturally-occurring protein backbone cross-linked by a synthetic polymer. Specifically, the present invention provides...
US20130052154 Compositions and Methods for the Treatment of Lung Inflammation  
Compositions and methods for the treatment of inflammation are provided.
US20140161762 DRUG DELIVERY OF TEMOZOLOMIDE FOR SYSTEMIC BASED TREATMENT OF CANCER  
The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a...
US20120328555 DRUG DELIVERY OF TEMOZOLOMIDE FOR SYSTEMIC BASED TREATMENT OF CANCER  
The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a...
US20100330025 Surface Independent, Surface-Modifying, Multifunctional Coatings and Applications Thereof  
The invention provides surface treatments that reduce or eliminate marine biofouling of various surfaces. A surface that is to be subjected to a marine environment can be treated with a mPEG-DOPA....
US20150010491 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY  
A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the...
US20140120053 POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY  
A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the...
US20110038828 MATRIX COMPOSED OF A NATURALLY-OCCURRING PROTEIN BACKBONE CROSS LINKED BY A SYNTHETIC POLYMER AND METHODS OF GENERATING AND USING SAME  
A method of treating a disorder characterized by tissue damage is provided. The method comprising providing to a subject in need-thereof a composition which comprises a synthetic polymer attached...
US20120070391 COSMETIC COMPOSITION COMPRISING AN AQUEOUS DISPERSION OF POLYSILOXANE/POLYUREA AND A SILANE, COSMETIC TREATMENT PROCESS AND KIT THEREFOR  
The present invention relates to a cosmetic composition comprising an aqueous dispersion of polysiloxane/polyurea copolymer and a silane, and to a cosmetic treatment process using said composition.
US20130243696 Compositions and Methods for the Treatment of Traumatic Brain Injury  
Compositions and methods for the inhibition and/or prevention of traumatic brain injury and the symptoms associated with it are provided.
US20130273122 Immobilised Biological Entities  
There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an anti-coagulant entity capable of...
US20130129664 Cancer Therapy Via Selective Uptake of Specialized Nanoparticles in Cancer Cells  
Disclosed herein are polymer/fullerene nanoparticles that have selective uptake into cancer cells, and which, upon being taken into the cancer cells induce apoptosis. Induction of apoptosis can be...
US20140314866 MATERIALS AND METHODS FOR MODULATING IMMUNE RESPONSES  
The present invention provides nanoparticle-coupled tolerogenic Treg cell therapy for treatment of immune and/or autoimmune disorders. In certain specific embodiments, the present invention can be...
US20100098654 TREATMENT OF NEUROBLASTOMA WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN  
The present invention relates to methods of treatment of neuroblastoma. The present invention includes administering polymeric prodrugs of 7-ethyl-10-hydroxycamptothecin to patients in need thereof.
US20110262381 FORMULATION FOR TREATMENT OF VAGINAL DRYNESS  
The present invention is directed to a composition for treating vaginal dryness and lack of lubrication comprising: a poloxamer component; a phospholipid component; an optional oil component; and...
US20140050689 TISSUE GRAFTED WITH A BIODEGRADABLE POLYMER  
Novel implantable tissue fixation methods and compositions are disclosed. Methods and compositions of tissue, fixed using polymeric and/or variable length crosslinks, and di- or polymercapto...
US20120076836 POLYION COMPLEX OF DOUBLE-STRANDED RIBONUCLEIC ACID  
Provided are a delivery system that is useful in delivering a double-stranded ribonucleic acid that functions in gene silencing in glomeruli, particularly in mesangial cells and the like, to the...
US20120027814 Polymeric Fibers Having Tissue Reactive Members  
A method for bonding a polymeric fiber to tissue is provided which includes providing a polymeric fiber having a plurality of tissue reactive members linked to a surface of the fiber via a...
US20140348754 Method of Delivering Therapeutics and Imaging Agents to the Brain by Nanoparticles that Cross the Blood Brain Barrier  
Described herein are methods of delivering a nanoparticle to the brain of a subject by administering to the subject a nanoparticle having a nanoparticle core and a targeting agent. A variety of...
US20110135700 IN SITU BULKING COMPOSITION  
The present invention relates to a hydrated, biocompatible tissue-augmentation compound and methodology for its implantation into mammalian tissue. The tissue-augmentation compound is comprised...
US20150125531 ACTIVE SELF-HEALING BIOMATERIAL SYSTEM  
Methods and compositions are provided that load and encapsulate an agent, such as a protein, in a porous self-healing polymer. A delivery system includes a porous self-healing polymer, an ionic...
US20140205542 Perfusive Organ Hemostasis  
Disclosed are compositions, methods and kits to control bleeding through the use of an internal occluder based on polymeric solutions, including use of reverse thermosensitive polymers in...
US20150209440 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE  
Particles and conjugates for delivering nucleic acid agents. Compositions containing the particles, the conjugates, or both. Methods of using the particles, the conjugates, and the compositions.
US20120258068 SCAFFOLDS FORMED FROM POLYMER-PROTEIN CONJUGATES, METHODS OF GENERATING SAME AND USES THEREOF  
Conjugates are provided herein which comprise a protein attached to at least two polymeric moieties, at least one of which exhibits reverse thermal gelation. The conjugates are suitable for being...
US20150132399 COMPOSITION AND METHOD FOR SULFATED NON-ANTICOAGULANT LOW MOLECULAR WEIGHT HEPARINS IN CANCER AND TUMOR METASTASIS  
A nanoformulation that includes nanoparticles. Each nanoparticle includes a shell in which a glycosaminoglycan (GAG is encapsulated. The GAG is ionically or covalently bonded to the shell. The GAG...
US20110250162 DISINFECTING AND DETOXIFYING META-ARAMID PARTICLES  
Porous, permeable particles of meta-aramid can be chlorinated or brominated to produce antimicrobial and detoxifying particles for use in applications such as, but not limited to, nonwoven webs,...
US20110206634 COMPOSITE MATERIAL FOR TISSUE REPAIR  
The present disclosure provides a biocompatible composite and method for its use in repairing tissue defects, including defects in cartilage. The biocompatible composite includes a fibrous...
US20140193356 Compositions Comprising Citrate And Applications Thereof  
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype...
US20150010490 ANTI-ADHESION POLYMER COMPOSITION CAPABLE OF SUPPORTING GROWTH FACTOR  
The present invention relates to an anti-adhesion polymer composition capable of supporting growth factor, which effectively exhibits anti-adhesion function and, at the same time, has an excellent...
US20110135736 Compositions and Methods for Producing Vascular Occlusion using a Solid-phase Platelet Binding Agent  
The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or...
US20110206753 NANOPARTICULATE COPPER COMPOUNDS  
The present invention relates to processes for the preparation of surface-modified nanoparticulate copper compounds and of aqueous suspensions which comprise surface-modified nanoparticulate...
US20140348896 Hydrophobic Tissue Adhesives  
Pre-polymers for use as tissue sealants and adhesives, and methods of making and using thereof are provided. The pre-polymers have flow characteristics such that they can be applied through a...
US20140065093 Compositions For Achieving A Therapeutic Effect In An Anatomical Structure  
Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect.
US20130028856 Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions  
Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and...
US20120171153 Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions  
Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and...
US20110059010 DUAL PHASE DRUG RELEASE SYSTEM  
The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure (I): wherein each occurrence of M is independently a...
US20140341996 Nanoengineering of Functionalized Polymers and Its Manufacturing and Formulation Methods for Personalized Cancer Therapies  
Nanoengineering of inert polymers to develop functionalized sulfonated polymers to harness the power of Alternate complement system to stimulate and amplify cytotoxic potentials of classical and...
US20110200655 Systems and methods that kill infectious agents (bacteria) without the use of a systemic anti-biotic  
A medical product is provided that is selected from at least one of, nasal cannulas, oxygen masks, wound dressings, bandages, band aids, catheters, endotrachial tubes, condoms, surgical and other...
US20110212048 POLYMALIC ACID-BASED MULTIFUNCTIONAL DRUG DELIVERY SYSTEM  
A structured drug system that is useful for delivering a drug payload to a specific tissue or cell type is disclosed. The system is based on purified polymalic acid. This polymer isolated from...
US20070286883 STRUCTURING HYDROGELS  
The present invention relates to a method for the preparation of a surface structured bulk hydrogel bearing a topographic and chemical pattern, comprising the steps of: (i) providing a primary...

Matches 1 - 50 out of 314 1 2 3 4 5 6 7 >