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US20110305777 |
DIMERIC IAP ANTAGONISTS
Smac mimetics that inhibit IAPs. |
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US20150110897 |
Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to... |
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US20150185219 |
Biomarker SPAG5
There has been a recent shift in cancer therapy from one size fits all to a personalized and tailored treatment for individual patients to increase efficiency and avoid unnecessary toxicity. This... |
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US20140186468 |
DIAGNOSING SUBSETS OF TRIPLE-NEGATIVE BREAST CANCER
The present invention provides a unique combination of biomarkers that identify triple-negative breast cancer (TNBC) patient subpopulations. Such subpopulations will have differential responses to... |
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US20140170241 |
COILED COIL HELIX CRISTAE MORPHOLOGY 1 (CHCM1) TUMOR MARKER AND CANCER THERAPEUTIC TARGET
Methods for diagnosing and treating a cancer or a tumor in a patient are provided. The methods can comprise the steps of obtaining a biological sample from the patient and analyzing the sample for... |
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US20120201747 |
System and Method for Diagnosis and Treatment
This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy... |
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US20150225800 |
METHODS AND ASSAYS FOR TREATMENT OF BLADDER CANCER
The technology described herein relates to methods of prognosing and treating bladder cancer. |
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US20140363522 |
Compositions and Methods for Treating and/or Preventing Cancer by Inhibiting Fatty Acid Binding Proteins
The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins. |
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US20110287110 |
COMBINATION CANCER TREATMENT
Described herein are methods of inhibiting the proliferation of cancer cells and methods of treating cancer, by administering a combination of a copper chelator and a platinum-based chemotherapeutic. |
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US20130121912 |
MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central... |
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US20120171306 |
THERAPEUTIC TREATMENT OF CANCER AND DYSPLASIA OF THE CERVIX OR VAGINA USING ESTROGEN ANTAGONISTS
A method for treatment of cervical or vaginal cancer and their associated dysplasia, including the steps of identifying a human cervical or vaginal cancer and/or dysplasia patient, administering... |
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US20120100134 |
GENETIC VARIANTS IN ANGIOGENESIS PATHWAY ASSOCIATED WITH CLINICAL OUTCOME
The invention provides methods for determining the clinical outcomes for treatment with various treatment regimens available to cancer patients based on genotypes of the patients for genetic... |
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US20150211009 |
MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central... |
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US20140186264 |
EXTRACELLULAR VESICLE-ASSOCIATED PROTEIN MARKERS OF CANCER
Extracellular vesicle-associated protein biomarkers for use in diagnosing and staging carcinomas, e.g., lung and ovarian cancers. |
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US20150139946 |
DETECTING MUTATIONS IN DISEASE OVER TIME
Provided is a method for monitoring a gene mutation associated with a cancer in a patient over time. Also provided is a method of selecting and/or applying treatment or therapy for a subject. |
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US20110286937 |
SYNTHETIC GLYCOLIPID-CONTAINING LIPOSOME
The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present... |
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US20110117078 |
Methods for the Treatment of Cancers
Methods for the treatment of cancers involving dysregulation of thromboxane receptor β (TP-β) are provided, including in certain aspects methods for diagnosing such cancers. Specific cancers... |
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US20110171323 |
METHODS AND KITS TO PREDICT PROGNOSTIC AND THERAPEUTIC OUTCOME IN SMALL CELL LUNG CANCER
Disclosed herein are methods used in the identification of cancer patients likely or unlikely to respond to systemic chemotherapy, methods of treating cancer patients based upon the... |
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US20150140123 |
Protein expression analyses for identifying genotoxic compounds
The invention relates to a method for screening compounds with (pro-)genotoxic activity by providing a system being capable of expressing a panel of defined proteins, incubating at least a portion... |
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US20140227284 |
SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER
Described herein are compounds, compositions and methods for treatment of cancer. Also described are methods and uses for identifying subject with cancer that are suitable for treatment with the... |
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US20130236567 |
GENE EXPRESSION SIGNATURE AS A PREDICTOR OF CHEMOTHERAPEUTIC RESPONSE IN BREAST CANCER
Disclosed are methods and compositions for determining and/or predicting a response to a therapy, especially a cancer therapy, including chemotherapy. Specifically, the disclosure provides... |
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US20120230952 |
DETECTION OF BLADDER CANCER
Provided are methods for detecting bladder cancer in a subject. In some aspects, methylation of one or more of MYO3A, CA10, NKX6-2, SOX11, DBC1, NPTX2, and/or A2BP1 in DNA sediment from a urine... |
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US20120034318 |
DIAGNOSTIC METHOD USING PALB2
The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also... |
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US20120070502 |
METHODS OF TREATING CANCER
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an... |
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US20110052672 |
TREATMENTS OF DISEASE OR DISORDERS USING NANOPARTICLES FOR FOCUSED HYPERTHERMIA TO INCREASE THERAPY EFFICACY
Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of... |
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US20110171228 |
Methods and Compositions Relating to the Regulation of Apoptosis by MUC1 and BH3-Containing Proapoptotic Proteins
This invention relates to regulation of cell signaling, cell growth, and more particularly to the regulation of cancer or immune cell growth. The invention provides methods of inhibiting... |
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US20140079813 |
Genes Associated With Post Relapse Survival And Uses Thereof
Provided are methods, systems and kits for predicting post-relapse survival of a cancer patient and for identifying cancer genes predictive of the post-relapse survival of the patient. Values... |
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US20110142917 |
COMPOSITIONS AND METHODS FOR TREATMENT OF EAR DISORDERS
The present invention relates to pharmaceutical compositions useful for topical, non-invasive delivery of an oligonucleotide to the ear and to methods for the treatment of an ear disorder,... |
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US20110311651 |
CARDENOLIDES FOR THE TREATMENT OF OCULAR CANCER
The instant invention provides methods of using a class of compounds known as cardenolides in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides... |
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US20140234295 |
ISOFLAVONOID COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in... |
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US20120207809 |
Method and system for effecting changes in pigmented tissue
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are... |
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US20110118528 |
Methods and Nutritional Formulations to Increase the Efficacy and Reduce the Side Effects of Cancer Treatment
The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides... |
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US20120321552 |
Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or... |
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US20110104050 |
Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or... |
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US20120237502 |
METHOD FOR TREATING BREAST CANCER AND OVARIAN CANCER
The present invention relates to a method for the prevention or treatment of certain breast cancers or ovarian cancer comprising administering to a patient in need thereof of a therapeutically... |
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US20110076343 |
Multiple Myeloma Treatments
Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided. |
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US20150072021 |
Methods and Kits for Predicting Outcome and Methods and Kits for Treating Breast Cancer with Radiation Therapy
The application describes methods and kits for screening subjects with breast cancer to determine if the breast cancer will be responsive to a post-mastectomy breast cancer therapy including... |
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US20150259751 |
MOLECULAR SIGNATURE FOR AGGRESSIVE SQUAMOUS CELL CARCINOMAS OF THE HEAD AND NECK
The present invention encompasses methods of classifying HNSCC tumors, such as OSCC tumors, as aggressive or, alternatively, indolent. |
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US20110059074 |
Knowledge-Based Proliferation Signatures and Methods of Use
The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a... |
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US20110033461 |
Combination Therapy for the Treatment of Cancer
Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed. |
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US20120323163 |
METHODS OF USING DUAL-EFFECT LIPOSOME IN THERAPY
The invention provides a method for treating target in need of such a treatments in a subject, comprising (a) administering a liposome containing a photosensitizer and a drug to a subject and (b)... |
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US20130122063 |
Nanotubes as Mitochondrial Uncouplers
A method of uncoupling mitochondria in a subject including administering nanotubes to the subject in a therapeutically effective amount, wherein the nanotubes are self-rectifying is provided. A... |
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US20130202717 |
MATERIALS AND METHODS FOR DIAGNOSING AND PREDICTING THE COURSE OF PROSTATE CANCER
Expression of Forkhead-box protein A1 (FOXA1), a transcription factor important for the normal development of the prostate gland is thought to be controlled by steroid hormones and GATA-3.... |
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US20110262560 |
Pigmented Emulsion Makeup Compositions With Gemstones
A pigmented emulsion composition comprising a water phase, an oil phase, and a plurality of gemstones in particulate form, and a method for providing a glow to the skin and ameliorating the... |
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US20120082736 |
Small-molecule TNF modulator to reduce the side effects of chemotherapy and radiotherapy
Cancer patients treated by chemotherapy and/or radiotherapy often suffer serious side effects. Currently, there is only one FDA approved and used as both a chemoprotector and a radioprotector,... |
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US20110044906 |
Methods for the Treatment, the Prognostic Assessment and the Staging of Non-Small Cell Lung Cancer
The present invention relates to methods for the treatment, the prognosis and the diagnosis of non-small cell lung cancer. |
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US20140328944 |
USE OF CTBP1 siRNA FOR THE TREATMENT OF GASTRIC CANCER
This invention encompasses a novel composition comprising silenced CTBP-1 combined with a compound selected from among 5-FU, Cisplatin and Epirubicin. The invention further relates to a method of... |
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US20110280963 |
COMBINATION THERAPY FOR THE TREATMENT OF CANCER
The present invention provides methods of sensitizing lung cancer cells to cisplatin and inhibiting the growth of lung cancer tumors by employing a modified eIF-4E antisense oligonucleotide and... |
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US20120141603 |
METHODS AND COMPOSITIONS FOR LUNG CANCER PROGNOSIS
Disclosed herein are methods and materials for prognosing survival of lung cancer patients, the methods comprising the detection of gains and losses of minimal common regions and/or genes... |
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US20110311629 |
NON-ADHESIVE ELASTIC GELATIN MATRICES
The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix... |