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US20150050359 |
DECELLULARISATION OF TISSUE MATRICES FOR BLADDER IMPLANTATION
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is... |
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US20150018966 |
DECELLULARISATION OF TISSUE MATRICES FOR BLADDER IMPLANTATION
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is... |
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US20150238537 |
Method and System for Treatment of Cardiovascular Disorders
Methods for treating a cardiovascular disorder comprising administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue... |
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US20150238536 |
Method and System for Treatment of Cardiovascular Disorders
Methods for treating a cardiovascular disorder comprising administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue... |
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US20140088339 |
Method and System for Treatment of Cardiovascular Disorders
Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular... |
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US20140335046 |
Compositions, Methods and Systems for Regenerative Cosmetics
A method of inducing or promoting hair growth on the scalp of a subject, comprising the steps of (i) providing an ECM composition including at least one ECM material, (ii) administering inciting... |
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US20150110754 |
High Resolution Allele Identification
Provided herein are methods for accurately determining the alleles present at a locus that is broadly applicable to any locus, including highly polymorphic loci such as HLA loci, BGA loci and HV... |
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US20110262498 |
Biologic Scaffold for Prevention of Pulmonary Fibrosis
Provided herein are methods of preventing, lessening or treating pulmonary fibrosis in a subject. The methods comprise delivering an amount of a powdered extracellular matrix (ECM)-derived... |
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US20140112890 |
INTRAOPERATIVE AND BLOOD DERIVED ADHESIVES
The invention features the production of an amine-reactive proteoglycan, specifically chondroitin sulfate or hyaluronic acid. This material can be provided in powder (solid) or liquid form and... |
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US20150164959 |
Compositions and Methods for Preventing Cardiac Arrhythmia
Disclosed herein are compositions and methods for treating or preventing cardiac arrhythmia in a subject. |
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US20140220095 |
Methods for Localized Modification of Tissue Products
Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a cross-linking... |
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US20120226218 |
EXTRACELLULAR MATRIX MATERIAL CREATED USING NON-THERMAL IRREVERSIBLE ELECTROPORATION
Extracellular matrix material is disclosed which is created by subjecting a target area to non-thermal irreversible electroporation (NTIRE) with a pulsed electrical field to kill cells in the... |
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US20150257786 |
Devices and Methods for Tissue Transplant and Regeneration
Devices and methods for transplanting tissue for the purpose of regeneration, for treating a patient having injured myocardial tissue, and/or for improving cardiac function through cell regrowth.... |
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US20140242184 |
Compositions for Regenerating Defective or Absent Myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an... |
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US20130129834 |
Compositions for Regenerating Defective or Absent Myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an... |
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US20130129833 |
Compositions for Regenerating Defective or Absent Myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an... |
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US20140271778 |
ENCAPSULATED KIDNEY TISSUE
Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said... |
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US20090142409 |
Extracellular Matrix Compositions for Tissue Regeneration
The invention is compositions of extracellular matrix that comprise mammalian extracellular matrix from two or more tissue sources in a mammal. The invention also includes methods of using these... |
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US20090130221 |
DECELLULARISATION OF TISSUE MATRICES FOR BLADDER IMPLANTATION
The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is... |
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US20050003017 |
Hypotensive and hypertensive properties of renomedullar extracts
Hypotensive and Hypertensive Activities from the Renal Medulla The present invention relates to novel hypotensive and hypertensive extracts obtainable from the renal medulla, methods for the... |
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US20140134264 |
USE OF MICROVESICLES (MVs) DERIVED FROM STEM CELLS FOR PREPARING A MEDICAMENT FOR ENDO/EPITHELIAL REGENERATION OF DAMAGED OR INJURED TISSUES OR ORGANS, AND RELATED TO IN VITRO OR IN VIVO METHODS
The invention relates to the use of microvesicles (MVs) derived from stem cells for preparing a medicament for the endo/epithelial regeneration of damaged tissues or organs and/or for inhibiting... |
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US20090186006 |
PLACENTAL VASCULAR LOBULE STEM CELLS
The present invention provides isolated populations of stem and progenitor cells from fetal vascular lobules of the placenta. The isolated populations of stem and progenitor cells of the invention... |
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US20120225056 |
METHODS AND COMPOSITIONS FOR TREATING COMPLEMENT-ASSOCIATED DISORDERS
The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and use of the compositions in methods for treating or preventing complement-associated... |
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US20080193554 |
Surgical Membrane
The invention relates to methods of processing amniotic membrane to generate a substantially ‘growth factor free’ membrane (GFF-membrane), and to methods of processing GFF-membrane to generate... |
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US20080260831 |
Extracellular Matrix-Derived Gels and Related Methods
Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as... |
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US20140342007 |
METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue... |
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US20140227364 |
METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue... |
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US20110083201 |
COMPOSITIONS FOR AND METHODS OF GRAZYME B INHIBITION
The present invention is related to the discovery that serpina3n, a secreted protein, binds to and inhibits granzyme B activity. The invention thus provides cells that include a polynucleotide... |
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US20150196679 |
HEMOSTATIC DEVICE
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site. |
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US20150037416 |
HEMOSTATIC DEVICE
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site. |
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US20130243738 |
SOLUBILIZATION OF ANTIGEN COMPONENTS FOR REMOVAL FROM TISSUES
The present invention relates to methods for removing antigens from tissues by sequentially destabilizing and/or depolymerizing cytoskeletal components and removing and/or reducing water-soluble... |
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US20090297622 |
SEPARATION AND FORMULATION OF BIOACTIVE FRACTION AND SUBFRACTION FROM CAMEL URINE WORK AS ANTICANCER AGENT
A pharmaceutical composition includes an effective amount of bio-active fraction PMF or subfraction PMFK obtained from the lyophilized camel urine or cow urine which coded in publications with... |
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US20130236453 |
Methods and Compositions for Modulating Acute Graft-versus-Host Disease using miR-155 Specific Inhibitors
Methods and compositions for treating or preventing acute graft-versus-host disease (aGVHD) in a subject using miR-155 specific inhibitors are described. |
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US20100221310 |
MEDICAL PRODUCTS INCLUDING MODIFIED EXTRACELLULAR MATRIX MATERIALS
Described, in certain aspects, are medical products comprised of uniquely prepared remodelable extracellular matrix (ECM) materials retaining at least a portion of their native bioactivity. Also... |
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US20150209478 |
Articles for Tissue Regeneration with Biodegradable Polymer
The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said... |
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US20080254139 |
METHODS AND COMPOSITIONS TO TREAT OVARIAN CANCER
The invention is a method of treating ovarian cancer by contacting a post-surgical site of an ovarian cancer patient with a composition or a sheet article comprising extracellular matrix to... |
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US20170160278 |
IgG Subtyping Assay for Identifying Transplantable Tissue Samples
The disclosure relates to methods for assessing the suitability of a tissue obtained from a vertebrate (e.g., human) donor for grafting to a recipient, such as another vertebrate of the same... |
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US20160129153 |
METHODS OF MANUFACTURING BIOACTIVE GELS FROM EXTRACELLULAR MATRIX MATERIAL
The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue... |
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US20160089477 |
POROUS FOAMS DERIVED FROM EXTRACELLULAR MATRIX, POROUS FOAM ECM MEDICAL DEVICES, AND METHODS OF USE AND MAKING THEREOF
The invention disclosed herein is directed to a porous wound healing foam composition that is made from an extracellular matrix of a mammal, method of making, and method of using. |
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US20160054336 |
METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal... |
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US20160051731 |
HYBRID GEL COMPRISING PARTICULATE DECELLULARIZED TISSUE
A hybrid gel comprising a particulate decellularized tissue (obtained by pulverizing animal-derived biological tissues that are decellularized (decellularized biological tissues)), fibrinogen and... |
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US20160030487 |
METHODS FOR SELECTION OF AGE-APPROPRIATE TISSUES
Methods of producing tissue matrices are provided. The methods can comprise selection of collagen-based tissues from animals based on desired mechanical and/or biologic properties relating to the... |
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US20160022868 |
Tissue Prostheses for Repairing, Reconstructing and Replacing Damaged or Diseased Biological Structures and Associated Tissue
Non-antigenic, resilient, bioremodelable, biocompatible tissue prostheses that can be engineered into a variety of shapes and used to repair, augment, reconstruct or replace damaged or diseased... |
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US20150366913 |
Biologic Scaffold For Prevention of Pulmonary Fibrosis
Provided herein are methods of preventing, lessening or treating pulmonary fibrosis in a subject. The methods comprise delivering an amount of a powdered extracellular matrix (ECM)-derived... |
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US20150359939 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device... |
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US20150359938 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device... |
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US20150359937 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device... |
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US20150359936 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device... |
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US20150359935 |
Extracellular Matrix Encasement Structures and Methods
A bioremodelable encasement structure comprising a pouch formed from at least one sheet of bioremodelable material, the pouch including an internal region that is configured to receive a device... |
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US20150359934 |
Articles for Tissue Regeneration with Biodegradable Polymer
The invention is also directed to particulate articles comprising extracellular matrix components that are encased in a biodegradable polymer composition. Methods of for treating damaged tissue... |