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US20160193299 MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS  
The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed...
US20160250153 NOVEL METHODS  
The present invention relates to the field of methods for providing components of pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to...
US20160058716 PHARMACEUTICAL FORMULATION CONTAINING GELLING AGENT  
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically...
US20090148517 MELT-EXTRUSION MULTIPARTICULATES  
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
US20070196478 ANTIVIRAL COMPOSITIONS  
The present invention is concerned with pharmaceutical compositions of antiviral compounds which can be administered to a mammal, in particular a human, suffering from a viral infection. These...
US20160143844 Drug Delivery Systems and Use Thereof  
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such...
US20140328937 Drug Delivery Systems and Use Thereof  
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such...
US20140065234 POLYMERSOMES, LIPOSOMES, AND OTHER SPECIES ASSOCIATED WITH FLUIDIC DROPLETS  
The present invention relates generally to vesicles such as liposomes, colloidosomes, and polymersomes, as well as techniques for making and using such vesicles. In some cases, the vesicles may be...
US20130209570 DRUG DELIVERY SYSTEMS AND USE THEREOF  
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such...
US20100221352 PHARMACEUTICAL COMPOSITION FOR THE ONCE-A-DAY ORAL ADMINISTRATION OF TROSPIUM CHLORIDE  
A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
US20080317854 PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED SOLID DOSAGE FORM  
The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a binder with a breaking...
US20080311182 MULTISTAGE DELIVERY OF ACTIVE AGENTS  
Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage...
US20080050450 Active Agent Formulations, Methods of Making, and Methods of Use  
Active agent compositions comprising active agent particles having an effective average particle size of less than 2000 nm, wherein the compositions comprise a particle sequestrant are disclosed....
US20150328160 REHYDRATABLE PHARMACEUTICAL PRODUCT  
A pharmaceutical product comprising lyophilised polymer matrix including a biologically active compound, of particular utility for embolisation, having improved rehydration properties is packaged...
US20140030352 NANODISPERSION  
The present invention provides a nanodispersion comprising nanoparticles having a mean size less than 300 nm dispersed in a vehicle comprising a water miscible solvent and water, said...
US20110293701 MULTIVALENT SYNTHETIC NANOCARRIER VACCINES  
The invention relates, at least in part, to compositions comprising populations of synthetic nanocarriers that comprise different sets of antigens as well as related methods.
US20100297252 NANOPARTICULATE MELOXICAM FORMULATIONS  
The present invention is directed to nanoparticulate compositions comprising meloxicam particles having an effective average particle size of less than about 2000 nm.
US20090232901 POLYMERIC MICROSPHERES  
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell...
US20090087487 Paliperidone sustained release formulation  
The present invention provides sustained release dosage forms comprising Paliperidone and processes for preparing the same.
US20090074830 ANTI-ANGIOGENIC COMPOSITIONS AND METHODS OF USE  
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic...
US20090004262 Nanoparticulate formulations and methods for the making and use therof  
The present invention is directed to size-stabilized drug nanoparticulate compositions and methods of preparation thereof.
US20070196491 DRUG DELIVERY SYSTEMS COMPRISING WEAKLY BASIC DRUGS AND ORGANIC ACIDS  
A pharmaceutical dosage form such as a capsule, a conventional or orally disintegrating tablet capable of delivering a nitrogen (N)-containing therapeutic agent having a pKa in the range of from...
US20100247668 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE  
Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms...
US20100247606 INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OCULAR CONDITIONS  
Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to...
US20100221356 PHARMACEUTICAL COMPOSITION FOR ONCE A DAY ADMINISTRATION OF TROSPIUM CHLORIDE  
A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
US20100203153 SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS USING THE SAME  
The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method...
US20090081309 Stabilized Oral Suspension Formulation  
Orally deliverable pharmaceutical compositions are provided comprising a drug of tow water solubility suspended in an aqueous liquid vehicle comprising a wetting agent, a thixotropic thickening...
US20160354320 DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME  
The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such...
US20100272822 NANOCELL DRUG DELIVERY SYSTEM  
Nanocells allow the sequential delivery of two different therapeutic agents with different modes of action or different pharmacokinetics. A nanocell is formed by encapsulating a nanocore with a...
US20100247669 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE  
Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms...
US20100196437 MEDICAL DEVICES HAVING A SURFACE INCLUDING A BIOLOGICALLY ACTIVE AGENT THEREIN  
The present invention provides a medical device, and methods of preparing and using a medical device. The medical device has a surface including a biologically active agent therein. The methods...
US20100104654 PROSTAGLANDIN AND PROSTAMIDE DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF  
Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma.
US20100074957 INTRAOCULAR FORMULATION  
Biodegradable therapeutic agent incorporating microspheres formulated in a high viscosity carrier suitable for intraocular administration to treat an ocular condition. The formulation can also be...
US20080069857 Compositions And Methods For Inhibiting Adhesions  
The present invention provides compositions and methods for inhibiting adhesions. The methods involve administering solutions containing hydrogel precursors such as polysaccharide derivatives,...
US20150037429 Controlled Release Microparticles  
Formulations for controlled, sustained release of biologically active agents for the treatment of ocular disorders have been developed. These formulations are based on solid microparticles formed...
US20110033553 Embolization  
A composition includes a plurality of particles. At least some of the plurality of particles include cross-linked polyvinyl alcohol and have a diameter of about 500 microns or less. The particles...
US20080292714 BONE TARGETING OF DEGRADABLE DRUG FILLED NANOPARTICLES  
This invention provides a method of modifying a cellular response in a mammal. The method comprises administering to the mammal an effective amount of biodegradable nanoparticles, each of said...
US20080145439 NANOPARTICLE DRUG FORMULATIONS  
A suspension of nanoparticles in a liquid medium provides a mechanism for delivery of gacyclidine base or other drug that is substantially insoluble in the liquid medium.
US20160346382 CARBOHYDRATE-MODIFIED PARTICLES AND PARTICULATE FORMULATIONS FOR MODULATING AN IMMUNE RESPONSE  
Disclosed are compositions, kits, and methods for modulating an immune response. The compositions and kits include and the methods utilize carbohydrate-modified particles having an immune...
US20160089336 Octreotide depot formulation with constantly high exposure levels  
The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and two different linear...
US20140099263 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE  
Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms...
US20130337078 PARTICULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS  
Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo...
US20090148527 INTRAOCULAR FORMULATION  
Biodegradable therapeutic agent incorporating microspheres formulated in a high viscosity carrier suitable for intraocular administration to treat an ocular condition. The formulation can also be...
US20090004283 Sustained Release Formulation Comprising Octreotide and Two or More Polylactide-Co-Glycolide Polymers  
The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and two or more different...
US20080279954 Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network  
A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the...
US20140348936 GASTRORETENTIVE CONTROLLED RELEASE VEHICLES THAT INCLUDE ETHYLENE COPOLYMERS, ETHYL CELLULOSES, AND/OR THERMOPLASTIC POLYURETHANES  
Gastroretentive controlled release vehicles may, in some embodiments, (1) comprise a polymeric matrix and agents for the treatment, prevention, and/or mitigation of a disease and/or side effect...
US20110064821 ENCAPSULATION OF BIOLOGICALLY ACTIVE AGENTS  
The present invention provides methods of encapsulating biologically active agents such as proteins in particulate carriers such as nanoparticles. Also provided are methods of delivery of proteins...
US20100098772 DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING NEOVASCULARIZATION  
Anti-angiogenesis compositions, and methods of using such compositions, useful for intraocular to treat neovascularization. The compositions can have viscosities at about 25° C. of at least about...
US20090053318 Forming Embolic Particles  
Methods of making polymer particles, as well as related particles, compositions, and methods are disclosed.
US20080181965 Loaded latex optical molecular imaging probes  
The present invention relates to a loaded latex particle comprising a latex material made from a mixture represented by formula (X)m-(Y)n-(Z)o-(W)p, wherein Y is at least one monomer with at least...

Matches 1 - 50 out of 220 1 2 3 4 5 >