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US20110293701 |
MULTIVALENT SYNTHETIC NANOCARRIER VACCINES
The invention relates, at least in part, to compositions comprising populations of synthetic nanocarriers that comprise different sets of antigens as well as related methods. |
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US20110287085 |
LIPOSOMAL CURCUMIN FOR TREATMENT OF CANCER
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of... |
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US20140328937 |
Drug Delivery Systems and Use Thereof
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such... |
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US20130209570 |
DRUG DELIVERY SYSTEMS AND USE THEREOF
The invention provides a microsphere formulation for the sustained delivery of an aptamer, for example, an anti-Vascular Endothelial Growth Factor aptamer, to a preselected locus in a mammal, such... |
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US20140294986 |
Microsphere Drug Delivery System for Sustained Intraocular Release
Disclosed are biodegradable microspheres between 40 μm and 200 μm in diameter that are effectively retained in the anterior chamber of the eye without producing hyperemia. The microspheres... |
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US20140314865 |
Vaccine Nanotechnology
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune... |
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US20130287857 |
Vaccine Nanotechnology
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune... |
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US20140065233 |
INJECTABLE MICROSPHERES FOR DERMAL AUGMENTATION AND TISSUE BULKING
The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions... |
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US20130323316 |
INJECTABLE MICROSPHERES FOR DERMAL AUGMENTATION AND TISSUE BULKING
The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions... |
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US20140193508 |
SURFACE BINDING OF NANOPARTICLE BASED DRUG DELIVERY TO TISSUE
Microparticles and nanoparticles and compositions thereof are provided. The microparticles and nanoparticles and compositions may be used for the treatment of musculoskeletal disease, such as... |
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US20140037749 |
Delivery Scaffolds and Related Methods of Use
The present invention relates to delivery systems. In particular, the present invention provides microporous scaffolds having thereon agents (e.g., extracellular matrix proteins, exendin-4) and... |
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US20150216810 |
CONTROLLED RELEASE HYDROCODONE FORMULATIONS
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt... |
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US20110217384 |
Modified Release Dosage Forms of Skeletal Muscle Relaxants
A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion... |
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US20150004243 |
OIL-IN-WATER METHOD FOR MAKING POLYMERIC IMPLANTS CONTAINING A HYPOTENSIVE LIPID
Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the subconjunctival space, in facilitating... |
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US20150196516 |
PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
Pharmaceutical formulations are described for use in the treatment of pulmonary arterial hypertension (PAH). The formulations comprise polymeric nanoparticles encapsulated within crosslinked... |
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US20130323177 |
TUMOR-TARGETING GAS-GENERATING NANOPARTICLE, METHOD FOR PREPARING THE SAME, AND TUMOR-TARGETING NANOPARTICLE FOR DRUG DELIVERY USING THE SAME
A tumor-targeting gas-generating nanoparticle, a method for preparing same and a tumor-targeting nanoparticle for drug delivery using same relate to a tumor-targeting gas-generating nanoparticle... |
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US20100303923 |
Endotoxin adsorbent for the prevention and treatment of autoimmune diseases
It is believed that the abnormal absorption of endotoxin present in the gastrointestinal tract relates to the pathogenesis of autoimmune diseases such as rheumatoid arthritis. In an animal model... |
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US20110008453 |
Stable Corticosteroid Nanoparticulate Formulations And Methods For The Making And Use Thereof
Disclosed are stable corticosteroid nanoparticulate formulations, methods of making and therapeutic uses thereof. |
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US20140314867 |
VITAMIN K2 MICROSPHERES
A vitamin K2 microsphere. The microsphere includes a poly(lactide-co-glycolide) acid (PLGA) particle, in which the Mw of PLGA is between 1000 and 300000, and the molar ratio between the lactide... |
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US20140099382 |
TREATMENT USING DANTROLENE
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH)... |
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US20110020427 |
Method Of Treating Malignant Solid Tumors Using Transcatheter Arterial Chemoembolization (TACE)
This invention is directed to methods of treating solid tumor cancers, particularly refractory cancers by administration of two pluralities of microparticles, one comprising drug-carrying... |
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US20150044296 |
COMBINATION THERAPY TO IMPROVE JOINT, TENDON, AND LIGAMENT HEALING
The present invention is directed to kit, drug combinations and methods for promoting endogenous bone marrow (BM)-derived vasculogenic progenitor cell (PC) mobilization, sensitization of such... |
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US20110081422 |
PROLONGED RELEASE OF LOCAL ANESTHETICS USING MICROPARTICLES AND SURGERY APPLICATIONS
Methods and compositions for providing long term pain relief in, for example, surgery recovery, including injecting a composition comprising a plurality of microparticles having different sizes... |
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US20110091564 |
INJECTABLE HOLLOW TISSUE FILLER
The present invention comprises a plurality of injectable hollow particulate fillers suspended in a biocompatible fluid carrier to significantly improve the clumping resistance and injectability... |
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US20150157762 |
METHOD FOR BONE FORMATION BY ADMINISTERING POLY(LACTIC-CO-GLYCOLIC ACID) CROSS-LINKED ALENDRONATE
A method for bone regeneration which comprises administering a short term release composition into a bone area of a subject in need thereof, wherein the composition comprises a... |
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US20140314868 |
PROSTAGLANDIN AND PROSTAMIDE DRUG DELIVERY SYSTEMS AND INTRAOCULAR THERAPEUTIC USES THEREOF
Biocompatible, bioerodible implants and microspheres include latanoprost and a biodegradable polymer effective, when placed intraocular (such as into the subtenon space) to treat glaucoma. |
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US20110129541 |
SUSPENSION DELIVERY SYSTEM FOR THE SUSTAINED AND CONTROLLED LOCAL RELEASE OF PHARMACEUTICALS
The invention relates to a novel suspension delivery system for the sustained and controlled release of pharmaceuticals. Methods of preparation and use are also disclosed. |
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US20100329982 |
PARTICLES WITH INDUCIBLE CHANGE OF SHAPE
The invention relates to particles which exhibit a stimulable shape change and allow control of their uptake in active cells. The particles can be used as carrier systems for bioactive molecules... |
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US20110008456 |
Controlled Release Corticosteroid Compositions and Methods for the Treatment of Otic Disorders
Disclosed herein are compositions and methods for the treatment of otic disorders with steroid, NSAID, and/or adenosine triphosphatase (“ATPase”) modulator agents. In these methods, the steroidal,... |
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US20100297251 |
ENCAPSULATED PARTICLES FOR ENTERIC RELEASE
The present invention provides a system for delivery of an enteric coated active agent generally resistant to disintegration in an neutral environment having one or more active agents encapsulated... |
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US20150017250 |
TAMPER-RESISTANT DOSAGE FORM CONTAINING ETHYLENE-VINYL ACETATE POLYMER
The invention relates to a tamper-resistant, oral pharmaceutical dosage form comprising a pharmacologically active ingredient having psychotropic action and an ethylene-vinyl acetate (EVA) polymer... |
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US20130295191 |
Stable Formulations for Lyophilizing Therapeutic Particles
The present disclosure generally relates to lyophilized pharmaceutical compositions comprising polymeric nanoparticles which, upon reconstitution, have low levels of greater than 10 micron size... |
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US20140302159 |
Cosmetic composition comprising a superabsorbent polymer and a lamellar or platelet-shaped matting mineral filler
The present invention relates to a composition for topical application, comprising at least one aqueous phase, at least one superabsorbent polymer and at least one lamellar or platelet-shaped... |
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US20080175921 |
Colloidal formulation of long-acting insulin and its preparation
The invention relates to injectable long-acting insulin formulations for the treatment of type I and II diabetes in humans and animals. The main objective of the invention is to provide a... |
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US20130280338 |
TAMPER RESISTANT AND DOSE-DUMPING RESISTANT PHARMACEUTICAL DOSAGE FORM
A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected... |
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US20140314866 |
MATERIALS AND METHODS FOR MODULATING IMMUNE RESPONSES
The present invention provides nanoparticle-coupled tolerogenic Treg cell therapy for treatment of immune and/or autoimmune disorders. In certain specific embodiments, the present invention can be... |
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US20110151015 |
IMMUNOMODULATOR PARTICLES AND METHODS OF TREATING
A method of stimulating an immune response in a subject including administering a micrometer-sized particle coupled with an antigen to the subject, wherein increasing the aspect ratio of the... |
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US20100297252 |
NANOPARTICULATE MELOXICAM FORMULATIONS
The present invention is directed to nanoparticulate compositions comprising meloxicam particles having an effective average particle size of less than about 2000 nm. |
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US20130323317 |
INJECTABLE AND SWELLABLE MICROSPHERES FOR TISSUE BULKING
The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The... |
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US20100323026 |
SUSTAINED RELEASE PREPARATION FOR TISSUE REGENERATION THERAPY
The object of the present invention is to provide a microsphere which has a slow-release period of from about two weeks to about four weeks following administration, enables a higher content of a... |
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US20110135744 |
Nanoparticle Based Therapy for Dispersing Mucin
There are provided compositions and methods to disperse mucin and/or actin using nanoparticles wherein the average diameter of the nanoparticles is less than about 1000 nm. |
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US20110059183 |
WATER-INSOLUBLE MEDICINE
A method of producing water-insoluble anti-cancer drug in the form of particulates, the method including preparing a water-insoluble anti-cancer drug having at least one multiple bond in the... |
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US20110052712 |
Sprayable Polymers As Adhesion Barriers
A formulation for generating an adhesion barrier that includes a plurality of particles or a dry powder that is made of a polymer combination of at least one biodegradable polymer and at least one... |
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US20110150971 |
ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier... |
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US20110150970 |
ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier... |
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US20110150969 |
ABUSE RESISTANT DRUGS, METHOD OF USE AND METHOD OF MAKING
An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier... |
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US20130251817 |
CANCER CELL TARGETING USING NANOPARTICLES
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of... |
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US20130251816 |
CANCER CELL TARGETING USING NANOPARTICLES
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of... |
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US20150132399 |
COMPOSITION AND METHOD FOR SULFATED NON-ANTICOAGULANT LOW MOLECULAR WEIGHT HEPARINS IN CANCER AND TUMOR METASTASIS
A nanoformulation that includes nanoparticles. Each nanoparticle includes a shell in which a glycosaminoglycan (GAG is encapsulated. The GAG is ionically or covalently bonded to the shell. The GAG... |
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US20140335193 |
CONTROLLED-RELEASE INJECTABLE MICROPARTICLE
The invention relates to a controlled-release injectable microparticle comprising a polyvinyl alcohol polymer and one or more hormones, in particular progesterone. Said microparticle induces... |