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US20130115286 |
ORAL ADMINISTRATION FORMS FOR CONTROLLED RELEASE OF RIFAMPICIN FOR THE TREATMENT OF BACTERIAL INFECTIONS AND INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT
Oral administration forms are described for the controlled release of an antibiotic selected from the group consisting of rifampicin, rifabutin, rifapentine, rifalazil and mixtures thereof, for... |
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US20140030348 |
DOSAGE FORMS FOR ORAL ADMINISTRATION AND METHODS OF TREATMENT USING THE SAME
The invention relates to dosage forms that provide prolonged therapy. In particular, the invention relates to dosage forms including various pluralities of drug-containing resin particles. The... |
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US20120128771 |
TIMED, PULSATILE RELEASE SYSTEMS
A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve target PK (pharmacokinetics) profiles... |
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US20120027845 |
Adenovirus AD36 E4 ORF1 Protein For Prevention and Treatment of Non-Alcoholic Fatty Liver Disease
This invention generally relates to methods for treating or preventing the symptoms of non-alcoholic fatty liver disease, methods for reducing excessive fat from the liver, methods of improving... |
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US20120251623 |
METHOD OF ADMINISTERING AN ACTIVE INGREDIENT USING A CHEWABLE ORAL DOSAGE FROM COMPRISING TEXTURE MASKED PARTICLES
In one aspect, the present invention features a method of administering an active ingredient, said method comprising chewing an oral dosage form comprising a texture masked particle, said texture... |
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US20120263794 |
TREATMENT OF EYE DISEASES USING ENCAPSULATED CELLS ENCODING AND SECRETING A NEUROPROTECTIVE FACTOR AND/OR AN ANTI-ANGIOGENIC FACTOR
The present application refers to cells, e.g. mesenchymal stem cells or mesenchymal stromal cells, or any further suitable cell, encoding and secreting a neuroprotective factor, an anti-angiogenic... |
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US20140328933 |
NOVEL FORMULATIONS AND METHODS
Nanoparticles comprising VIP and their use in treating, e.g. pulmonary hypertension. Such nanoparticles provide improved delivery of VIP and allow for acute treatment and optionally for sustained... |
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US20140322341 |
NOVEL HEMOSTATIC PATCH AND USES THEREOF
Disclosed herein is a novel hemostatic patch that may be used to control and/or arrest bleeding in patients. The patch offers an effective but also minimally invasive way to control and/or arrest... |
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US20130280325 |
COMPRESSED SOLID DOSAGE FORMS
This invention relates to compressed solid oral dosage form able to contain a high load of active pharmaceutical ingredient, showing a controlled release profile, and consisting of individual... |
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US20140370111 |
PROTEIN DELIVERY FROM STEM CELL MICROCARRIERS
Disclosed are methods and compositions of microbead carriers for delivery of cells and other biologically active substances to diseased or damaged tissue in a subject in need thereof. |
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US20120064168 |
METHODS OF TREATMENT USING A GASTRIC RETAINED GABEPENTIN DOSAGE
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. |
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US20130243868 |
NOVEL FORMULATIONS
Nanoparticles comprising T3 and their use in treating, e.g., cardiac conditions, for example cardiac arrest, are provided. Such nanoparticles provide improved delivery of T3 and allow for acute... |
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US20150050336 |
Taste Masking System For Non-Plasticizing Drugs
The present invention relates to taste masking system, taste masked formulations, dosage forms made from those formulations and methods of making those formulations that involve dissolving or... |
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US20110165256 |
COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPLASIA
In accordance with the present invention, there are provided methods for treating hyperplasia in a subject in need thereof. In another aspect of the invention, there are provided methods for... |
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US20110256228 |
Solid Forms for Tissue Repair Background of the Invention
This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair. |
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US20120076735 |
Nanoparticles for Extravascular Administration
Disclosed are drug delivery systems and methods for extravascular administration of drug, vaccine, and/or diagnostic agents, for use in research and medical applications. |
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US20120207842 |
MULTIPARTICULATE L-MENTHOL FORMULATIONS AND RELATED METHODS
Enteric coated multiparticulate formulations that use L-menthol as an active ingredient are disclosed. In one embodiment, the multiparticulate formulation comprises a plurality of particulates... |
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US20120225122 |
Abuse-Resistant Formulations
This disclosure relates to a sustained-release oral dosage form for once-a-day administration comprising a matrix containing a viscosity modifier and coated granules containing hydromorphone. The... |
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US20110244051 |
PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF OVERACTIVE BLADDER
Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof;... |
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US20130129829 |
Encapsulation and Controlled Release of Small Molecules for Intracellular Delivery Using Thermally Responsive Nanocapsules
In accordance with certain embodiments of the present disclosure, a method for intracellular delivery of small molecules is provided. The method includes encapsulation of small molecules in a... |
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US20130039990 |
INJECTABLE, LOAD-BEARING CELL/MICROBEAD/CALCIUM PHOSPHATE BONE PASTE FOR BONE TISSUE ENGINEERING
The invention provides injectable, stem cell-containing calcium phosphate bone pastes for bone tissue engineering and methods of making and using the same. |
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US20130266660 |
ALCOHOL-RESISTANT METOPROLOL-CONTAINING EXTENDED-RELEASE ORAL DOSAGE FORMS
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing metoprolol or a pharmaceutically... |
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US20130089599 |
NANO-ENCAPSULATED THERAPEUTICS FOR CONTROLLED TREATMENT OF INFECTION AND OTHER DISEASES
This invention relates to a method to provide immediate, direct and controlled time release of an effective amount of therapeutics to a wound site for a prolonged period. The pharmaceutical... |
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US20110206771 |
Encapsulated functional fine particle composition capable of spraying and preparation method thereof
Provided is an encapsulated functional fine particle composition capable of spraying that is useful for hemostasis and wound protection and allows a patient to treat the wound by oneself.... |
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US20120263788 |
CONTROLLED RELEASE HYDROCODONE FORMULATIONS
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof,... |
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US20150030683 |
FORMULATIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF PRE-MCI AND/OR PRE-ALZHEIMER'S CONDITIONS
In certain embodiments the methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's... |
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US20120308656 |
SUGAR-COATED PREPARATION AND PRODUCTION METHOD FOR THE SAME
A method is provided for producing a sugar-coated preparation including a solid composition containing a pharmacologically active ingredient and a sugar coating layer. The method comprises a step... |
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US20130330279 |
NANOPARTICLE MEDIATED GENE THERAPY, DIAGNOSTIC PRODUCTS AND THERAPEUTIC PRODUCTS FOR BREAST CANCER
The present disclosure provides compositions and methods of treating Breast Cancer. Disclosed is a nanoparticle paired to at least one of W genetic materials that suppress key regulators of fat... |
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US20130245357 |
Magnetic Nanoparticle Formulations, Methods for Making Such Formulations, and Methods for their Use
The present invention provides derivatized magnetic nanoparticles, methods for making such nanoparticles, and methods for their use. |
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US20140349850 |
Coated Dehydrated Microorganisms with Enhanced Stability and Viability
The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of... |
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US20130337070 |
Coated Nanoparticle Therapy for Skin Cancer
Disclosed herein are compositions useful as therapy and prevention of skin neoplasms, namely melanoma. Also disclosed herein are methods of using polymer-coated cerium nanoparticles as therapy... |
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US20110223256 |
Method For Stabilizing Flavonoid Aqueous Dispersion
A method for suspending microparticulated water insoluble bioactive compound in a beverage by incorporating solubilized or dispersed microparticulated compound and at least one dispersion... |
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US20110045063 |
PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF
The present invention provides, among other things, compositions and methods suitable for the treatment of hyperphosphatemia based on phosphate-binding magnesium salts. In some embodiments, the... |
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US20130156858 |
Formulations Preserving Bioactivity and Methods of Their Preparation
A pharmaceutical composition comprising an alginate hydrogel core where a bioactive agent is entrapped. The water content of the hydrogel is at least 10% of equilibrium water content. The beads... |
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US20070264326 |
Anti-misuse oral microparticle medicinal formulation
The field of the present invention is that of solid microparticulate analgesic oral medicines. The invention is that of providing novel analgesic medicines which allow at the same time the... |
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US20110052713 |
REPAIRING DAMAGED NERVOUS SYSTEM TISSUE WITH NANOPARTICLES
The present application relates to reduction of acrolein-mediated cell death following neural insult. According to at least one embodiment, chitosan is utilized as a membrane fusogen to restore... |
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US20120328704 |
POWDER COMPOSITIONS FOR INHALATION
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also... |
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US20120315336 |
INJECTABLE NANOPARTICULATE OLANZAPINE FORMULATIONS
Described are injectable formulations of particulate olanzapine that produce a prolonged duration of action upon administration, and methods of making and using such formulations. The injectable... |
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US20150258070 |
Oral Dosage Forms of Bendamustine and Therapeutic Use Thereof
In the present invention there is provided a pharmaceutical composition for oral administration which comprises bendamustine or a pharmaceutically acceptable, ester, salt or solvate thereof as an... |
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US20120231084 |
GALENIC FORM SUITABLE FOR ABSORBING, IN A SPECIFIC MANNER, THE UNDESIRABLE MOLECULES IN THE DIGESTIVE TRACT
The present invention relates to a galenic form comprising particles capable of specifically adsorbing the undesirable molecules present in the digestive tract, to the method for preparing same... |
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US20110206772 |
POLYSACCHARIDE COMPOSITION AND METHODS OF ISOLATION OF THE EMULSION STABILIZING CATIONIC POLYELECTROLYTIC POLYSACCHARIDE
The present invention relates to purification and use of a novel emulsion stabilizing polysaccharide. In particular, a polyelectrolyte exopolysaccharide with high molecular weight comprising a... |
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US20120015039 |
SUSTAINED RELEASE OF NUTRIENTS IN VIVO
Nutritional compositions delivered in vivo in a time controlled manner sustainable over long periods of time, provide enhancing athletic performance, increased hand/eye coordination and... |
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US20130189368 |
NANOPARTICULATE COMPOSITION CONTAINING ANTIBIOTICS FOR INTRAMAMMARY ADMINISTRATION IN ANIMALS
The present invention relates to the development of two types of polymer nanocapsules to encapsulate cloxacillin benzathine, an antimicrobial drug. More specifically, this invention relates to a... |
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US20110027174 |
NANOTUBES FOR CANCER THERAPY AND DIAGNOSTICS
The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT),... |
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US20120058192 |
SUNSCREEN COMPOSITIONS
Sunscreen compositions containing a discontinuous oil phase dispersed in a continuous water phase, at least 10% by weight of an organic UV-filter, a water-insoluble, C2-C8, liquid silicone, a... |
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US20130230595 |
Methods of Using Multilayer Magnetic Micelle Compositions
Provided herein is a method of transfecting a brain cell of a subject with a polynucleotide comprising systemically administering to the subject a composition comprising a micelle having a... |
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US20120277517 |
Formulation and Methods for Enhanced Interventional Image-Guided Therapy of Cancer
An embodiment in accordance with the present invention provides a thermo-chemoembolization formulation and method for enhanced interventional image-guided therapy for cancer. The T-C formulation... |
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US20150030684 |
IRRIGATION RESISTANT COMPOSITIONS FOR REGENERATION OF HARD TISSUES AND METHODS AND KITS OF USING THE SAME
An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers is described. Also,... |
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US20140377365 |
SUSTAINED-RELEASE FORMULATION OF ROTIGOTINE
Provided herein are methods and compositions for producing formulations systemic delivery of dopamine agonists via the oral inhalation route. Specifically, provided herein are methods and... |
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US20150231269 |
DELIVERY OF THERAPEUTIC COMPOUNDS WITH IRON OXIDE NANOPARTICLES
The present invention relates to the field of drug delivery, in particular the delivery of unmodified cargo molecules (such as doxorubicin and Taxol®) using iron oxide nanoparticles as therapeutic... |