Matches 1 - 50 out of 64 1 2 >


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US20090136465 Therapeutic Gene-Switch Constructs and Bioreactors for the Expression of Biotherapeutic Molecules, and Uses Thereof  
The present invention relates to methods and compositions for treating, ameliorating or preventing a disease or disorder in a subject by introducing into cells of the subject a therapeutic gene...
US20070134293 Devices and methods for the delivery of blood clotting materials to bleeding wounds  
An apparatus for promoting the clotting of blood comprises a receptacle, at least a portion of which is defined by a mesh having openings therein, and particles of clay retained in the receptacle....
US20060195176 Coated implantable medical device  
Bioactive-coated medical devices are provided, including coated vascular stents. The medical device coating can include a coating layer posited over at least a portion of the medical device...
US20050079201 Implants with functionalized carbon surfaces  
The invention relates to a method of producing medical implants having functionalized surfaces by providing a medical implant with at least one carbon-based layer on at least one part of the...
US20160213812 BIODEGRADABLE POLYMER AND TISSUE COMBINATIONS  
A biodegradable bioprosthesis can include a biodegradable tissue and a biodegradable polymer combined with the biodegradable tissue. The biodegradable tissue can be non-crosslinked tissue, EDC...
US20080166391 Zero-order prolonged release coaxial implants  
A coaxial implant has been developed using entirely biodegradable polymeric materials. As referred to herein, a coaxial implant is a device having a core containing drug, surrounded by a...
US20080075833 Rate-reducing membrane for release of an agent  
A membrane that reduces the rate at which a therapeutic substance is released from an implantable medical device, such as a stent, is disclosed.
US20050004558 Flexible vascular inducing implants  
Implants and associated delivery systems for promoting angiogenesis in ischemic tissue are provided. The implants may be delivered percutaneously, thoracically or surgically and are particularly...
US20070026039 Composite self-cohered web materials  
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
US20110027188 Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers  
An implantable medical device is disclosed having a plurality of smaller particles contained in a plurality of larger particles and configured to be released from the larger particles when the...
US20050070989 Medical devices having porous layers and methods for making the same  
The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices...
US20050060044 Methods and devices for maintaining patency of surgically created channels in a body organ  
This is directed to methods and devices suited for maintaining an opening in a wall of a body organ for an extended period. More particularly devices and methods are directed maintaining patency...
US20090238855 LAMINATE SHEET ARTICLES FOR TISSUE REGENERATION  
The invention is to articles of extracellular matrix. The articles comprise one or more sheets of mammalian extracellular matrix laminated together. A single sheet can be folded over and laminated...
US20070269483 Method and apparatus for installation of dental implant  
An organ derived from genetic material is inserted in a patient's body. Genetic material is inserted at a selected site in the body to grow an organ.
US20080286332 Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties  
The present invention relates to implantable medical devices coated with phosphoryl choline acrylate polymer topcoat layer, an acrylate copolymer layer containing a therapeutic agent, and their...
US20070026040 Composite self-cohered web materials  
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
US20050100580 Hydrophilic coated medical device  
A medical device comprises a main body, a therapeutic agent and a radiation-curable hydrophilic coating. The hydrophilic coating allows for easy insertion of medical devices, which may include...
US20170157294 OPTIMIZATION OF ALGINATE ENCAPSULATION OF ISLETS FOR TRANSPLANTATION  
Apparatus is provided, including a plurality of islets, and a hydrogel configured to macroencapsulate the plurality of islets. The hydrogel is implantable in a subcapsular space (21) of a kidney...
US20070243227 Coatings for surgical staplers  
A material with a first state and a second state is applied to a surgical stapler. The stapler is applied to tissue in a surgical field while the material is in the first state. Subsequently, the...
US20110086083 IMPLANT DEVICES FOR MODULATING BIOACTIVE AGENT RELEASE PROFILES  
Described herein are implant devices comprising at least one exposed biodegradable inner core surface, the inner core being surrounding partially by a membrane sheath which comprises a...
US20090287072 POLYMER COMPOSITIONS, COATINGS AND DEVICES, AND METHODS OF MAKING AND USING THE SAME  
The disclosure provides for a biocompatible, thromboresistant coating including a chalcogenide compound that induces nitric oxide formation; and a biocompatible matrix incorporating the...
US20060062826 Process for the production of sustained release drug delivery devices  
Disclosed is an improved sustained release drug delivery device and method of producing such device. The device comprises a drug core in an impermeable cup or impermeable coating layer that is...
US20050118229 Implantable drug delivery device for sustained release of therapeutic agent  
An implantable drug-delivery device that utilizes a nanopore diffusion membrane in combination with a microporous hydration membrane for achieving long-term, zero-order release of a therapeutic...
US20100255059 Artificial micro-gland  
A micro-scale artificial gland is disclosed in the form of an independent unit for promoting biological activity. The artificial gland includes cells formed in a membrane enclosing a reservoir....
US20070116736 Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury  
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to...
US20060029639 Biodegradable substrate, prosthetic material for tissue regeneration, and cultured tissue  
A biodegradable substrate usable as a prosthetic material (i.e., for tissue regeneration) facilitates the invasion of cells into a substrate and has a thick structure similar to woven fabrics. The...
US20150030657 SMOOTH MUSCLE CELL CONSTRUCTS  
The present invention relates to the regeneration, reconstruction, augmentation or replacement of luminal organs or tissue structures in a subject in need using scaffolds seeded with autologous or...
US20090035350 Polymers for implantable devices exhibiting shape-memory effects  
The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed...
US20070231364 Biocompatible Membrane and Process for Producing the Same  
The present invention provides a biocompatible membrane which has a configuration that conforms well to an affected part and can be used in fields such as dentistry, oral surgery, orthopedics,...
US20070134292 Synthetic, bioabsorbable polymer materials and implants  
The invention relates to synthetic, bioabsorbable polymer materials and implants, like fibres, sutures, meshes and other tissue management, wound closure or tissue engineering devices, which...
US20100310627 Xenotransplant for Stroke Therapy  
Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.
US20140248328 Methods of treating amniotic membranes using supercritical fluids and compositions and apparatuses prepared therefrom  
A method of sterilizing compositions prepared from amniotic membrane tissues may include harvesting placental tissue, separation of amniotic membrane tissue, and treatment of the amniotic membrane...
US20140255462 Xenotransplant Compositions and Methods of Stroke Therapy  
Disclosed are implant compositions and methods for treatment of neurological diseases of the central nervous system of a mammal.
US20070213835 PLASTIC IMPLANT IMPREGNATED WITH AN ANTIBIOTIC  
A plastic device containing an effective amount of an antibiotic to minimize bacterial and/or fungal infection at the site of implantation is disclosed.
US20070087032 Composition of cartilage therapeutic agents and its application  
A cartilage therapeutic composition is developed for clinical transplantation into articulatio genu (knee joints) or ankle joints. It has clinical significance for symptomatic cartilage defects of...
US20150024024 Cell Lines That Produce Prostaglandin F2 Alpha (PGF2A) And Uses Thereof  
Cells and cell lines that are genetically modified to express the hCox-2 enzyme, which results in the upregulation of prostaglandin F2 alpha (PGF2a) on the cells have been obtained. Encapsulated...
US20100196439 Angiogenesis Mechanism and Method, and Implantable Device  
Various methods and devices are provided for providing therapy to a living body. In one embodiment, an implanted permeable container has living cells provided therein, and various nutrients and/or...
US20160058911 MULTI-STEP METHOD FOR FABRICATING TISSUE ENGINEERING BONE  
A multi-step method for fabricating a tissue engineering bone comprises the following steps: (1) scaffold repair and pre-vascularization: fabricating a tissue engineering bone scaffold at a bone...
US20090269389 ARPE-19 as a Platform Cell Line for Encapsulated Cell-Based Delivery  
ARPE-19 cells were evaluated as a platform cell line for encapsulated and unencapsulated cell-based delivery technology. ARPE-19 cells were found to be hardy (the cell line is viable under...
US20160067390 METHODS FOR IN VIVO AND IN VITRO USE OF GRAPHENE AND OTHER TWO-DIMENSIONAL MATERIALS  
Two-dimensional materials, particularly graphene-based materials, having a plurality of apertures thereon can be formed into enclosures for various substances and introduced to an environment,...
US20110045055 MEDICAL DEVICES CONTAINING THERAPEUTIC AGENTS  
According to one aspect of the invention, implantable or insertable medical devices are provided which can delay release of one or more therapeutic agents for a predetermined time after...
US20070067045 Systems and methods for skin wrinkle removal  
An implant is disclosed that reduces wrinkles. The implant may be in the shape of a cylinder with a constant or a varying cross-section and length. The implant contains a gel that has limited flow...
US20160296670 BONE SEMI-PERMEABLE DEVICE  
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
US20100316690 Modular assembly of tissue engineered constructs  
Scaleable, vascularised tissue constructs that are composed of a multiplicity of cell containing, discrete and separable modules, methods of fabricating same and uses thereof. The tissue construct...
US20100203101 BIO-MEMBRANE FOR TISSUE REGENERATION  
A bio-membrane with angiogenic activity for implant in tissue regeneration and repair, including bone reconstruction and the repair of skin and soft tissue lesions is described, essentially...
US20100260816 INDUCTION OF IMMUNOLOGICAL TOLERANCE  
A method of creating tolerance to transplanted cells, tissue, or organs without the need for continuous immunosuppression. A tolerizing dose of a cell or tissue within a membrane structure is...
US20070154518 Photoactive biocompatible coating composition  
The present invention discloses a biocompatible coating composition that can be photo crosslinked when exposed to long wavelength ultraviolet light. The biocompatible coating composition comprises...
US20090010991 Nasal Passage Stent  
A drug coated nasal stent implant that provides filtration of environmental pollutants and airborne allergens from inhaled air regulating the air before it is ingested into the remainder of the...
US20060034886 Bonded fiber structures for use in controlling fluid flow  
A flow control element is provided for use in selectively controlling the flow of a liquid through an annular conduit. The flow control element comprises a self-sustaining, three dimensional...
US20050222688 Transmural concentric multilayer ingrowth matrix within well-defined porosity  
A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of...

Matches 1 - 50 out of 64 1 2 >