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US20130317590 Stent And Delivery System With Reduced Chemical Degradation  
Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.
US20110257726 SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION  
Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The...
US20100310622 DRY EYE TREATMENT BY PUNCTA PLUGS  
A punctal plug and method of treating dry eyes are provided. The punctal plug has two or three layer structure and contains at least one drug, for treating conditions such as dry eyes contained in...
US20150174153 CHITOSAN HYDROGEL FOR REPAIRING NERVE TISSUE  
The present invention relates to chitosan hydrogel microparticles of a median size d50 comprised between 1 and 500 μm (obtained from a number distribution), the chitosan having a degree of...
US20100316686 Osteosynthesis with nano-silver  
The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus...
US20150231208 Treatment of Allodynia, Hyperalgsia, Spontaneous Pain, and Phantom Pain  
The present invention relates to use of Cometin in a method of treatment of allodynia, hyperalgesia, spontaneous pain and/or phantom pain. In a preferred embodiment the disorder to be treated is...
US20140271766 METHODS AND DEVICE FOR TREATING OPIOID ADDICTION  
The invention described herein solves the challenges encountered in providing a safe, efficacious, and satisfactory option for the treatment of opioid addiction. Methods and devices of the...
US20140328892 USE OF ALFIMEPRASE IN THE TREATMENT OF THROMBOSIS  
Methods for treatment of arterial or venous thrombosis in patients undergoing an endovascular intervention or a surgical procedure, and more particularly, administering alfimeprase directly into...
US20150258241 INJECTABLE ALLOPLASTIC IMPLANTS AND METHODS OF USE THEREOF  
Described herein are injectable alloplastic implant compositions that are particularly useful for soft tissue defect augmentation. The compositions include microparticles, such as...
US20140030307 NEW COMBINATION COMPRISING N-ACETYL-L-CYSTEINE AND ITS USE  
A combination of N-acetyl-L-cysteine, selenium in the form of selenomethionine and melatonin, and a medical product or pharmaceutical composition comprising such combination, useful for the...
US20130224276 COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS  
Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or...
US20110129513 COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS  
Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or...
US20130071462 Drug Delivery Systems and Applications  
Certain embodiments of the invention include medical materials and methods comprising a biodegradable hydrophilic hydrogel comprising dispersed lipophilic particles that comprise a therapeutic...
US20110123591 TUMORICIDAL, BACTERICIDAL, OR VIRICIDAL MACROPHAGE ACTIVATION  
The activation of macrophages and methods for treating cancer, bacterial pathogens and viral pathogens are disclosed. In particular, Gc protein is converted to Gc-macrophage activating factor...
US20110165215 COHESIVE OSTEOGENIC PUTTY AND MATERIALS THEREFOR  
Described is an implantable medical material comprising a malleable, cohesive, shape-retaining putty including mineral particles, insoluble collagen fibers and soluble collagen. The medical...
US20150004205 BIOMATERIALS HAVING NANOSCALE LAYERS AND COATINGS  
The invention generally relates to surfaces having a protein-resistant hydrogel layer and methods for preparing a protein-resistant hydrogel layer on a surface. The protein-resistant hydrogel...
US20140308331 INTERPOLYMER NETWORK DELIVERY SYSTEM  
This invention relates to compositions and applications for an interpolymer network delivery system containing iodine.
US20140178448 CONTINUOUS CULTURING DEVICE  
A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold...
US20120114734 NANOSTRUCTURE SURFACE COATED MEDICAL IMPLANTS AND METHODS OF USING THE SAME  
Compositions including a surface or film comprising nanofibers, nanotubes or microwells comprising a bioactive agent for elution to the surrounding tissue upon placement of the composition in a...
US20140271765 METHODS AND DEVICE FOR TREATING OPIOID ADDICTION  
The invention described herein solves the challenges encountered in providing a safe, efficacious, and satisfactory option for the treatment of opioid addiction. Methods and devices of the...
US20110014260 SYSTEM AND METHOD FOR LIVER CELL CULTURE AND MATURATION  
The present invention relates to systems and methods for maturation, proliferation and maintenance of function in cells presenting hepatocyte characteristics and differentiated from stem cells....
US20140356407 BIODEGRADABLE SUPPORTING DEVICE  
A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of...
US20110223231 FRAGMENTED POLYMERIC COMPOSITIONS AND METHODS FOR THEIR USE  
Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and...
US20150079145 PROTEIN STABILIZATION FORMULATIONS  
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including...
US20150010607 LIQUEFACTION OF BONE MATRIX  
The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The...
US20110159069 Medical Implants and Methods of Making Medical Implants  
A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane...
US20110070283 Coating For Implantable Devices And A Method Of Forming The Same  
Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active...
US20110293685 SCAFFOLDS FOR TISSUE ENGINEERING AND REGENERATIVE MEDICINE  
The methods and compositions described herein relate to novel 3-dimensional porous scaffolds useful for tissue re-generation, enhancement, or tissue repair. Electrospinning or other methods are...
US20110236454 INJECTABLE DRUG DELIVERY FORMULATION  
The invention provides an injectable formulation that includes an active agent; a biocompatible solvent system, crosslinkable polymers such as polysaccharides; and crosslinking agents; wherein the...
US20150125505 REDUCTION OF IMPLANT INFECTION VIA TUNABLE STIMULATION OF LOCALIZED ADAPTIVE IMMUNE RESPONSE  
Compositions, implantation devices and methods for stimulating an immune response to infection are discussed. In some examples, the compositions, implantation devices or methods of regulating the...
US20110287080 COATING II  
The invention relates to a coating composition for an implantable medical device, a method of coating a medical device and a device coated with the composition.
US20120015020 BIODEGRADABLE DRUG OR OTHER ACTIVE DELIVERY SYSTEM  
A nonwoven fabric has been developed as a delivery system for drugs or other actives which includes biodegradable and biocompatible fibers with plant virus nanoparticles. The plant virus...
US20140271472 METHODS AND DEVICES FOR LUNG VOLUME REDUCTION WITH EXTRACELLULAR MATRIX MATERIAL  
Lung volume reduction by isolating a target lung portion from the rest of the lung with a mass of extracellular matrix (“ECM”) material. The procedure can be performed by locating a tube within...
US20140086971 DRUG-ELUTING ROTATIONAL SPUN COATINGS AND METHODS OF USE  
Drug-eluting rotational spun coatings that include one or more therapeutic agents may be used to coat a medical device. The medical devices include, for example, balloon catheters, vascular grafts...
US20110014267 BIOSYNTHETIC CARTILAGINOUS MATRIX AND METHODS FOR THEIR PRODUCTION  
An isolated, acellular biosynthetic cartilaginous matrix substantially devoid of synthetic biodegradable scaffold structure is provided. Through a method with the steps of a) contacting in vitro a...
US20140341963 Device for the Treatment of Bone Conditions  
A composition comprising at least one substance coated with an agent wherein the agent forms a liquid impermeable but gas permeable layer surrounding the said substance and preventing the passage...
US20150182559 Compositions for Repair of Defects in Tissues, and Methods of Making the Same  
Tissue repair compositions, particularly bone repair compositions, containing (a) bone fragments and (b) homogenized connective tissue, and methods for making the same are provided. Some of the...
US20110045044 COMPOSITIONS FOR REPAIR OF DEFECTS IN TISSUES, AND METHODS OF MAKING THE SAME  
Tissue repair compositions, particularly bone repair compositions, containing (a) bone fragments and (b) homogenized connective tissue, and methods for making the same are provided. Some of the...
US20140079752 Injectable, Pore-Forming Hydrogels for Materials-Based Cell Therapies  
The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the...
US20150024020 DRUG DELIVERY SYSTEM AND METHOD OF MANUFACTURING THEREOF  
An apparatus and method provides a drug layer formed on a surface region of a medical device, the drug layer comprised of a drug deposition and a carbonized or densified layer formed from the drug...
US20110135707 POLYHYDROXYALKANOATES FOR IN VIVO APPLICATIONS  
Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or...
US20110142905 COATED TABLETS WITH REMAINING DEGRADATION SURFACE OVER THE TIME  
The present invention relates to a pharmaceutical composition for controlled delivery of at least one active ingredient into an aqueous phase, said pharmaceutical composition comprising: a tablet,...
US20120021038 COATING COMPOSITION  
A wound spacer device comprising multiple beads connected by non-absorbable suture material is disclosed. The device can be applied, for example, by a first responder to an injured individual, or...
US20150238660 Porous Biomaterial  
A synthetic osteoinductive porous biomaterial is provided comprising: a network of interconnected micropores, wherein the microporosity is 23% by volume or more; wherein the surface free energy of...
US20110054615 POROUS BIOMATERIAL  
A synthetic osteoinductive porous biomaterial is provided comprising: a network of interconnected micropores, wherein the microporosity is 23% by volume or more; wherein the surface free energy of...
US20110142901 SUSTAINED RELEASE COMPOSITION  
A sustained release apparatus including at least one sustained release mini-implant or pellet; the or each mini-implant or pellet including: a sustained release support material; and a...
US20130136784 METHODS FOR DELIVERY OF MEDICATION USING DISSOLVABLE DEVICES  
A method utilizing a dissolvable device for the internal delivery of medication and more particularly to the use of fibers or non-woven fabrics made of a safe polymer material incorporating a...
US20110262515 FENESTRATED WOUND REPAIR SCAFFOLD  
Fenestrated wound repair scaffolds and methods for forming scaffolds involve dispersing human collagen having a preserved amount of native constituents in solution, depositing the human collagen...
US20110002972 NEUROENDOCRINE FACTORS FOR TREATMENT OF DEGENERATIVE DISEASES  
The present invention is related to the use of a repellent factor and/or polypeptide for manufacturing of a pharmaceutical composition for treating a disease such as a degenerative disease in...
US20140056962 DRUG DELIVERY SYSTEM  
The subject invention provides a drug delivery system comprising at least one compartment comprising (i) a drug-loaded thermoplastic polymer core layer, (ii) a drug-loaded thermoplastic polymer...