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US20140178438 INDIVIDUALIZED VACCINES FOR CANCER  
The present invention relates to the provision of vaccines which are specific for a patient's tumor and are potentially useful for immunotherapy of the primary tumor as well as tumor metastases....
US20150093416 AUTOLOGOUS TUMOR VACCINES AND METHODS  
Autologous anti-cancer vaccines and methods of manufacture and treatment are provided, including expansion of individual patient-derived tumor cells in an immune-compromised animal(s) to attain,...
US20130156813 BIOMARKERS FOR PROSTATE CANCER AND METHODS FOR THEIR DETECTION  
The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient...
US20110150935 TARGETED TREATMENT FOR PATIENTS WITH ESTROGEN RECEPTOR NEGATIVE AND PROGESTERONE RECEPTOR NEGATIVE BREAST CANCERS  
Treatments for estrogen receptor and progesterone receptor negative breast cancer or estrogen receptor, progesterone receptor and c-erbB2 negative (triple negative) breast cancer are provided.
US20130309271 Method for Producing a Vaccine for the Treatment of Cancer  
The present invention discloses a method for producing a haptenized vaccine from a tissue biopsy. The method includes obtaining a tissue biopsy, isolating the cells, irradiating the cells,...
US20150132285 Proteinase-engineered Cancer Vaccine Induces Immune Responses to Prevent Cancer and to Systemically Kill Cancer Cells  
The present invention provides a method of making a proteinase-engineered cancer vaccine for treating a cancer patient, especially for cancer patient at advanced/metastatic stage. The cancer...
US20130177595 NANO-VEHICLE DERIVED FROM TUMOR TISSUE, AND CANCER VACCINE USING SAME  
The present invention relates to a cancer vaccine, and specifically, to a pharmaceutical composition for treating cancer containing a nano-vehicle derived from tumor tissue, and a method for...
US20110212090 Combinatorial Analysis and Repair  
A method for the repair of a unit, by specific diagnosis of the undesired state, and its appropriate repair, using said specific diagnosis as a means to repair in an appropriate way said unit. The...
US20120034242 CYTOKINE-EXPRESSING CELLULAR VACCINE COMBINATIONS  
The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a...
US20120195928 VACCINES AND METHODS FOR USING THE SAME  
Compositions comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with one or more of CTACK protein, TECK protein, MEC protein and functional fragments...
US20110110979 METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES  
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus...
US20110070268 Method  
Methods for characterisation of patients as responders or non-responders to therapy based on differential expression of one or more genes are provided. Gene expression profiles, microarrays...
US20110236314 METHOD OF DETECTION AND DIAGNOSIS OF ORAL AND NASOPHARYNGEAL CANCERS  
The present invention relates to cancer and in particular to oral and nasopharyngeal cancers. In particular, the present invention relates to a method of detection and diagnosis of oral squamous...
US20150218649 BIOMARKER ASSOCIATED WITH RISK OF MELANOMA REOCCURRENCE  
The present invention provides a method of predicting the risk of reoccurrence of melanoma in a patient from whom melanoma tissue was previously removed which comprises the following: a. obtaining...
US20110274723 CANCER IMMUNOTHERAPY AND METHOD OF TREATMENT  
The instant disclosure relates to methods for treating a cancer patient with an active immunotherapeutic, wherein the methods include assessing a patient's pre-existing immunoreactivity to at...
US20130045180 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20120195852 VACCINES, IMMUNOTHERAPEUTICS AND METHODS FOR USING THE SAME  
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines,...
US20130064857 METHODS AND MATERIALS FOR MAKING AND USING VACCINES  
This document relates to methods and materials for making and using vaccines. For example, vaccine preparations (e.g., whole cell vaccines and cell lysate vaccines) that can be used to treat...
US20100310469 VACCINE IMMUNOTHERAPY FOR IMMUNE SUPPRESSED PATIENTS  
A method of immunotherapy to treat cancer or a synergistic anti-cancer treatment by administering an effective amount of natural cytokine mixture (NCM), an effective amount of cyclophosphamide...
US20140030296 VACCINE ADJUVANT  
A method for enhancing a vaccine therapy effect by a vaccine composition. The method including a step of implanting β-tricalcium phosphate in an inside of a body of a subject, and a step of...
US20120100102 CANCER VACCINE  
We disclose a vaccine comprising a pappalysin and vaccine compositions comprising a pappalysin.
US20150139946 DETECTING MUTATIONS IN DISEASE OVER TIME  
Provided is a method for monitoring a gene mutation associated with a cancer in a patient over time. Also provided is a method of selecting and/or applying treatment or therapy for a subject.
US20110229502 Ablative immunotherapy  
The invention disclosed herein relates generally to immunotherapy and, more specifically, to the use of immunotherapy for treating tumors and pathogen infected tissues by first priming patients...
US20140227286 Annexin A2 as Immunological Target  
AnnexinA2 (ANXA2), a member of the Annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by the post-vaccination sera of patients...
US20110293608 ANNEXIN A2 AS IMMUNOLOGICAL TARGET  
AnnexinA2 (ANXA2), a member of the Annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by the post-vaccination sera of patients...
US20120164180 Cancer Vaccines and Therapeutic Methods  
Compositions and methods of producing improved cancer vaccines are described. In addition, methods of identifying tumor associated antigens are also described.
US20130189301 Ablative immunotherapy  
The disclosure herein relates generally to immunotherapy and, more specifically, to the use of immunotherapy for treating tumors and pathogen infected tissues. The immunotherapy relates to first...
US20110033376 Treatment of Melanoma  
There is described dexanabinol, or a derivative thereof, for the treatment of melanoma. There is also described a method of treating a patient suffering from melanoma.
US20130287857 Vaccine Nanotechnology  
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune...
US20110171211 HEAT SHOCK PROTEIN GP96 VACCINATION AND METHODS OF USING SAME  
The invention provides a tumor cell genetically modified to express a nucleic acid encoding a secreted form of a heat shock protein (hsp) gp96 polypeptide. The invention also provides a method of...
US20150203919 METHODS FOR PREDICTING THE SURVIVAL TIME AND TREATMENT RESPONSIVENESS OF A PATIENT SUFFERING FROM A SOLID CANCER WITH A SIGNATURE OF AT LEAST 7 GENES  
The present invention relates to a method for predicting the survival time of a patient suffering from a solid cancer comprising i) determining in a tumor sample obtained from the patient the gene...
US20120039943 FACTORS  
A method for determining a prognosis for benefit for a cancer patient receiving immunotherapy treatment involving (a) measuring a level of platelets and haemoglobin in a sample from the cancer...
US20120164099 USE OF HUMAN PROSTATE CELL LINES IN CANCER TREATMENT  
This invention is concerned with agents for the treatment of primary, metastatic and residual cancer in mammals (including humans) by inducing the immune system of the mammal or human afflicted...
US20130295043 VACCINATION IN ELDERLY PATIENTS  
The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in an elderly patient preferably exhibiting an age of at...
US20140341974 Liposomal Vaccine Adjuvants and Methods of Making and Using Same  
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidicholine (DPPC), dipalmitoyl phosphatidylglycerol (DPPG), dioleoyl...
US20120030780 TARGETING OF SALL4 FOR THE TREATMENT AND DIAGNOSIS OF PROLIFERATIVE DISORDERS ASSOCIATED WITH MYELODYSPLASTIC SYNDROME (MDS)  
The present invention discloses nucleic acids, proteins, and antibodies for SALL4 (including isoforms SALL4A, SALL4B, and SALL4C), a zinc finger transcriptional factor. Further, methods are...
US20110027322 TUMOR VACCINE, A METHOD FOR PRODUCING A TUMOR VACCINE AND A METHOD FOR CARRYING OUT ANTITUMOR IMMUNOTHERAPY  
The group of inventions relates to medical engineering, in particular to the immunotherapy of cancer patients. The inventive tumor vaccine based on surface tumor antigens comprises a mixture of...
US20150152402 METHOD OF PRODUCING RECOMBINANT PROTEINS WITH MANNOSE-TERMINATED N-GLYCANS  
We describe a method of expressing a recombinant protein comprising mannose-terminated N-glycans from a host cell, the method comprising: (a) introducing a nucleic acid encoding a recombinant...
US20140205635 DETECTION OF PRAME GENE EXPRESSION IN CANCER  
The present invention relates to PRAME specific primers and probes, diagnostic kits and methods. The invention further relates to treatment of specific populations of cancer patients suffering...
US20140065100 Compositions and Methods for Cancer Immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
US20110250171 Compositions and Methods for Cancer Immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
US20110159043 ALLOGENEIC VACCINE AND METHODS TO SYNTHESIZE SAME  
This invention provides a retroviral vector comprising (a) a 3′LTR; and (b) an insert having (i) a promoter, (ii) a sequence encoding an immunomolecule selected from the group consisting of...
US20140105934 METHOD FOR ENHANCING IMMUNE RESPONSE IN THE TREATMENT OF INFECTIOUS AND MALIGNANT DISEASES  
The present invention pertains to a new approach for the treatment of infectious and malignant diseases. The present invention provides new DNA and protein vaccines for the treatment of infectious...
US20130115245 Vaccine for Tumor Immunotherapy  
The present invention relates to a vaccine comprising dendritic cells and bacterial ghosts for tumor immunotherapy.
US20100330105 Anticancer Combination Therapies  
Methods for treating or preventing hyperproliferating diseases, e.g., cancer, are described. A method may comprise administering to a subject in need thereof a therapeutically effective amount of...
US20130039908 PROGNOSTIC MARKERS AND METHODS FOR PROSTATE CANCER  
The present invention relates to methods and compositions for the diagnosis, prognosis and treatment of neoplastic disorders. Some embodiments include methods, compositions, and kits for the...
US20140341970 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT  
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant...
US20140193459 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT  
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant...
US20140037691 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT  
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant...
US20130224233 IMMUNOTHERAPEUTIC METHOD FOR TREATING PROSTATE CANCER  
The invention relates to treatment of prostate cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a portion of a prostatic...