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US20120301540 METHOD OF TREATMENT FOR BLADDER DYSFUNCTION  
Liposomes are used for intravesical drug delivery, especially delivery of botulinum toxin (BoNT) to help improve lower urinary tract symptoms by decreasing bladder irritation and frequency. The...
US20110206731 BOTULINUM TOXIN THERAPY FOR SKIN DISORDERS  
Methods for treating skin disorders by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a skin disorder.
US20140350483 Injections  
A syringe containing a compressible porous matrix, which compressible porous matrix has in it a pharmaceutical in a soluble glass, Methods of producing and using the syringe, and compressible...
US20120251576 Treatment of Nasal and Sinus Disorders  
Disclosed herein are compositions and methods for treating nasal and sinus conditions, and symptoms thereof, with botulinum toxin (BoNT).
US20110142882 Control of blood flow in skin, subcutaneous tissue and muscle by botulinum toxin, snare protein mediating substances, and alpha adrenergic agents by either injection of transdermal delivery systems  
Methods for controlling abnormal blood flow in disease states by the selective alteration of the components of microvascular flow using Botulinum A Toxin, other SNARE protein mediating agents,...
US20110052636 METHOD FOR TREATING PREMATURE EJACULATION WITH A BOTULINUM NEUROTOXIN  
Methods for prolongation of climax time in a patient in need thereof are presented, as are methods for treating premature ejaculation by local administration of a Clostridial neurotoxin, such a...
US20130273120 METHODS AND COMPOSITIONS FOR INTRANASAL DELIVERY  
Provided herein are methods for generating dry vaccine powder formulations. Dry vaccine powder formulations can be used for intranasal delivery. Also provided are methods for stimulating local...
US20130129781 METHODS AND COMPOSITIONS FOR INTRANASAL DELIVERY  
Provided herein are methods for generating dry vaccine powder formulations. Dry vaccine powder formulations can be used for intranasal delivery. Also provided are methods for stimulating local...
US20110038892 COMPLEXING SYSTEM  
The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from...
US20120225094 Treatment of Sleep Disordered Breathing with Neurotoxin  
Disclosed herein are compositions of neurotoxins and methods of their use for the treatment of sleep disordered breathing. In one embodiment of the present invention, a method of treating sleep...
US20120039940 METHODS FOR TREATING UTERINE DISORDERS  
A method for treating uterine disorders, including hyperplasic, hypertonic, cystic and/or neoplastic uterine gland tissue by local administration of a botulinum toxin to or to the vicinity of the...
US20100278867 Use of botulinum toxin for the treatment of chronic facial pain  
The present invention includes a method of treating pain caused by neuralgia comprising administering botulinum toxin to an afflicted area of a patient. The pain may be caused by trigeminal...
US20110076305 EXTRACELLULAR MATRIX MATERIALS AS VACCINE ADJUVANTS FOR DISEASES ASSOCIATED WITH INFECTIOUS PATHOGENS OR TOXINS  
Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases...
US20120207809 Method and system for effecting changes in pigmented tissue  
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are...
US20130315957 METHOD OF TREATING VERTIGO  
The invention is a method for reducing the symptoms of vertigo. The method is performed by delivering a therapeutically effective amount of presynaptic neurotoxin, such as Botulinum Toxin A, in a...
US20110038893 THERAPEUTIC USE OF AT LEAST ONE BOTULINUM NEUROTOXIN IN THE TREATMENT OF PAIN ASSOCIATED WITH DIABETIC NEUROPATHY  
The present invention relates to at least one botulinum neurotoxin for treatment of prevention of pain associated with diabetic neuropathy wherein said botulinum neurotoxin is prepared for local...
US20120093827 TREATMENT OF AUTOIMMUNE DISORDERS WITH A NEUROTOXIN  
Methods of treating one or more autoimmune disorders include a step of administering a Clostridial neurotoxin, such as a botulinum toxin, to a patient that has an autoimmune disorder. In one...
US20140370056 Mucosal Vaccine Using Cationic Nanogel  
A mucosal vaccine for the prevention or treatment of microbial infections is described that is capable of inducing vaccine antigen-specific immune responses in an organism without the addition of...
US20110280909 METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE  
Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are...
US20120231034 USE OF BOTULINUM NEUROTOXIN TO TREAT SUBSTANCE ADDICTIONS  
The present invention provides methods for treating a substance addiction- related behavior in a patient with a substance addiction, comprising the step of locally administering a therapeutically...
US20120315297 Treatment of Psychological Trauma  
The present specification discloses methods of treating a psychological trauma in an individual using botulinum toxins and/or a Targeted Exocytosis Modulator, and compositions thereof.
US20100303756 Methods of Treating Urogenital-Neurological Disorders Using Interleukin Retargeted Endopepidases  
The present specification discloses TVEMPs, compositions comprising such toxins and methods of treating urogenital-neurological disorders in a mammal using such TVEMPs and compositions.
US20120237548 PHARMACEUTICAL COMPOSITIONS CONTAINING BOTULINUM NEUROTOXIN  
This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides....
US20110280908 MULTIMERIC PROTEIN TOXINS TO TARGET CELLS HAVING MULTIPLE IDENTIFYING CHARACTERISTICS  
The present invention provides compositions comprising modified bacterial toxins and methods for using the modified bacterial toxins for targeting particular cell populations and for treating...
US20100266638 HEADACHE TREATMENT METHOD  
Herein disclosed are methods for treating headache, such as a chronic migraine for example, by administration of botulinum toxin to fixed specific locations of a patient at a fixed amount, as well...
US20070065463 Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions  
The invention is directed to topical formulations and methods of treating a migraines and/or cluster headaches, muscle sprains, muscle spasms, spasticity, tension headaches, tension related...
US20130022543 Method for Treating and Confirming Diagnosis of Exertional Compartment Syndrome  
Described is a method of treating chronic compartment syndrome in a muscle of a mammal, particularly exertional compartment syndrome. The method includes introducing an effective amount of a...
US20120114697 TREATMENT OF HOLOCRINE GLAND DYSFUNCTION WITH CLOSTRIDIA NEUROTOXINS  
Methods of using clostridial toxins and other biological agents to control holocrine gland dysfunction in humans is provided. In preferred embodiments the methods provide beneficial effects in humans.
US20120263781 METHODS AND COMPOSITIONS FOR TREATING RHINITIS  
Improved efficacy in treatment of rhinitis with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for administration of the botulinum toxin. The liposomes are...
US20120189572 VACCINES TARGETING CELLULAR DEATH RECEPTORS  
The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells...
US20130344106 Methods and Compositions for Improving Immune Response by a Nutraceutical Antioxidant  
The present invention provides a new means of restoring the immune system in aging and immunocompromised individuals using an antioxidant nutraceutical. The nutraceutical stimulates the aging...
US20110293663 Pharmaceutical botulinum toxin compositions  
Botulinum toxin, a well know systemic poison, produces favorable therapeutic effect by virtue of regionally attaching to nerves within the myoneural junction and possibly other tissues in a target...
US20110200639 Botulinum toxin treatments of Depression  
Methods for preventing or treating depression including a depression mediated by the thalamus. Depression, including a thalamically mediated depression, can be treated by peripheral administration...
US20110184330 INACTIVATION OF SMOOTH MUSCLE TISSUE  
Treatment and procedures for treating bodily conduits involves deactivating, killing, or otherwise treating smooth muscle tissue of the conduit.
US20150132302 Vaccine and uses thereof  
The present disclosure provides immunogenic compositions, such as vaccines, including DNA vaccines, and uses thereof, e.g., to suppress or prevent an immune response and/or to treat or prevent an...
US20130189307 METHOD OF TREATING DEPRESSION  
Methods are disclosed herein for treating depression in the subject. A method includes the use of Botulinum toxin to cause paralysis of a facial muscle, such as the depressor anguli oris,...
US20150140033 C. PERFRINGENS ALPHA TOXOID VACCINE  
The present invention describes vaccines that comprise C. perfringens Type alpha toxoids, antigenic fragments thereof, inactivated antigenic fragments of C. perfringens Type alpha toxins, or any...
US20140234422 Vaccine Composition With Aluminium Hydroxide Nanoparticles  
A vaccine composition comprising at least one antigen and one adjuvant, characterized in that the adjuvant comprises sterile-filterable nanoparticles comprising pseudo-boehmite and polyacrylate.
US20120107361 Albumin-Free Botulinum Toxin Formulations  
This invention relates to botulinum toxin formulations that are stabilized without the use of any proteinaceous excipients. The invention also relates to methods of preparing and using such...
US20100330123 ALBUMIN-FREE BOTULINUM TOXIN FORMULATIONS  
This invention relates to botulinum toxin formulations that are stabilized without the use of any proteinaceous excipients. The invention also relates to methods of preparing and using such...
US20070259001 Cosmetic use of botulinum toxin for the treatment of eyebrow and forehead ptosis, and unwanted eyebrow expression  
A method of temporarily elevating the eyebrow position and softening undesirable glabellar muscle activity to affect a more desirable appearance. In a broad aspect the invention comprises...
US20120251574 Endopeptidase and Neurotoxin Combination Treatment of Multiple Medical Conditions  
The present specification discloses Clostridial neurotoxins and TEMs, compositions comprising such Clostridial neurotoxins and TEMs, methods of treating a multiple medical disorder in an...
US20110243991 PROCESS FOR PRODUCTION OF VACCINES  
The invention relates to a process for the production of a vaccine against bacterial pathogens which produce an AB toxin, like Clostridium, comprising (a) culturing the pathogen under conditions...
US20110177116 Methods of Immunizing Pregnant Heifers at Three Months of Gestation  
The present invention discloses methods for protecting newborn calves against neonatal diarrhea by vaccinating pregnant cows and/or pregnant heifers, while minimizing the number of separate...
US20130183344 RECOMBINANT VACCINE AGAINST CLOSTRIDIUM PERFRINGENS INFECTION AND EPSILON TOXIN INTOXICATION  
The present invention relates to generation and high level expression of recombinant non-toxic of epsilon toxin of Clostridium perfringens as a recombinant vaccine against Clostridium perfringens...
US20080057084 Methods for selecting headache patients responsive to botulinum toxin therapy  
A method for treating a headache by selecting a patient determined to be responsive to administration of a botulinum neurotoxin for treatment of a headache by determining that the patient has or...
US20150030612 IMMUNIZATION AGAINST CLOSTRIDIUM DIFFICILE DISEASE  
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile...
US20130177592 IMMUNIZATION AGAINST CLOSTRIDIUM DIFFICILE DISEASE  
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile...
US20100028385 TREATMENT OF EXCESS CERUMEN SECRETION  
Presently descibed are methods useful in treating outer ear conditions generally associated with the secretion of cerumen. The methods comprise the step of locally administering a therapeutically...
US20070020294 Use of botulinum toxin for treatment of articular pathologies  
Use of botulinum toxin to obtain a product intended to be administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip,...
Matches 1 - 50 out of 249 1 2 3 4 5 >